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The map label for this gene is pelA

Identifier: 156937048

GI number: 156937048

Start: 219077

End: 220117

Strand: Reverse

Name: pelA

Synonym: Igni_0253

Alternate gene names: 156937048

Gene position: 220117-219077 (Counterclockwise)

Preceding gene: 156937049

Following gene: 156937047

Centisome position: 16.96

GC content: 60.81

Gene sequence:

>1041_bases
GTGCGAGTCTTAGAGGTCAACGAGTCTAAGGGGGAAGTCAAGGTAAGGGTGGAAGACGAGGAGGACGTGTGGATCTTACA
CAGCGCCTTGAGGCCCGGGGACTTGGTCCGGGCGAGGACCGCCAGGAGCGTGGCGGGGAGCTCCGGCAAGGAAAAGATAC
CCATGACGTTGACCATTAAGGTCACGGGCTCGGAGTTCCAAGCGTTCAGCAACGTATTGAGGGTCAAGGGGGTAGTCGTA
GAGGGGCCGGACAAGTTCGGCTTAATAGGCTCGCACCACGCGATAAAGGTCTACCCGGGGAAGGAGATAACCATAATTAG
GGAGAGGGGCCTCGCGCAGCTCTTGGAGAGGCTCAAGAAGGGGGAGGAGAGGAAGCCCCAAGTCCCGGTCCTCGCTGTGG
ACTACGACGAGTACTCCTTAGCGGTGGTCAGGGGACAAGGAATAGAGTGGGTCTTCGAGGGCTCCCTCAGGCTCCCGGGG
AAGGGGGACGAGGGCCGCGAGGCGGCGACCGAGAGGAAGATAAACGAGCTGGCGAAGAGGGTTTCTGAGGAGCTGAAGTT
AAGAAACCTCGACCACGTGGTAGTGGTGGGCCCCGGGTTCCTTAAGGACAAGGTCGCCCAACGCTTGTCCGAGGAAGGCT
TCAAGGTTAAGGTGGACAGCGCCTCCTCCGGGGGGAGGGCGGGCGTCTTAGAGGCGATAAGGAAGGGCTCCTTGAGGGGG
GTCGCGAAGGAGCTGGAGAGCATCAAAGCTCTCGAGGCCCTCGAGGAGTTCGTGAAACACGTCGCCCGGGGCGACGGGTA
CGCGCTCTACGGGGTCGACGACTGTATGACCGCCGCCCAAGCGAACGCGGTTAAAACCCTCATAATATCGGACGACCTCT
TGCACTCCCCCGACTTAGGGGAGAGGGCGGTGGAGTTGGTGGAGCTCGCGGAGAAGAAGGGCGCGGAAGTGATAATAGTG
CCCAAGGGGACCGAGGCTTGGGAGAGGCTGAGGCCCTTCGGCGACGTGGTGTGTTTGCTGCGCTTCCCCATTTCTCTATA
G

Upstream 100 bases:

>100_bases
ATCCCGGCGGCGGCCCCACCAAAGCCTCTCACGGCTTACATTCCTCGAGCGCCGCGTCCCAACGAATTAACTCTTCCCGG
AAGGCCCTCCGGGGTCCAAA

Downstream 100 bases:

>100_bases
GCTCCCCCTCGTCCCCGGAACCGGGAGAAGGCAGTGGGTAAGGTGCTATGCTTGACCCCGCCCAAGGGGCTGTGCGACGG
CTTGGTGGCTTCCTTGAACG

Product: translation factor pelota

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MRVLEVNESKGEVKVRVEDEEDVWILHSALRPGDLVRARTARSVAGSSGKEKIPMTLTIKVTGSEFQAFSNVLRVKGVVV
EGPDKFGLIGSHHAIKVYPGKEITIIRERGLAQLLERLKKGEERKPQVPVLAVDYDEYSLAVVRGQGIEWVFEGSLRLPG
KGDEGREAATERKINELAKRVSEELKLRNLDHVVVVGPGFLKDKVAQRLSEEGFKVKVDSASSGGRAGVLEAIRKGSLRG
VAKELESIKALEALEEFVKHVARGDGYALYGVDDCMTAAQANAVKTLIISDDLLHSPDLGERAVELVELAEKKGAEVIIV
PKGTEAWERLRPFGDVVCLLRFPISL

Sequences:

>Translated_346_residues
MRVLEVNESKGEVKVRVEDEEDVWILHSALRPGDLVRARTARSVAGSSGKEKIPMTLTIKVTGSEFQAFSNVLRVKGVVV
EGPDKFGLIGSHHAIKVYPGKEITIIRERGLAQLLERLKKGEERKPQVPVLAVDYDEYSLAVVRGQGIEWVFEGSLRLPG
KGDEGREAATERKINELAKRVSEELKLRNLDHVVVVGPGFLKDKVAQRLSEEGFKVKVDSASSGGRAGVLEAIRKGSLRG
VAKELESIKALEALEEFVKHVARGDGYALYGVDDCMTAAQANAVKTLIISDDLLHSPDLGERAVELVELAEKKGAEVIIV
PKGTEAWERLRPFGDVVCLLRFPISL
>Mature_346_residues
MRVLEVNESKGEVKVRVEDEEDVWILHSALRPGDLVRARTARSVAGSSGKEKIPMTLTIKVTGSEFQAFSNVLRVKGVVV
EGPDKFGLIGSHHAIKVYPGKEITIIRERGLAQLLERLKKGEERKPQVPVLAVDYDEYSLAVVRGQGIEWVFEGSLRLPG
KGDEGREAATERKINELAKRVSEELKLRNLDHVVVVGPGFLKDKVAQRLSEEGFKVKVDSASSGGRAGVLEAIRKGSLRG
VAKELESIKALEALEEFVKHVARGDGYALYGVDDCMTAAQANAVKTLIISDDLLHSPDLGERAVELVELAEKKGAEVIIV
PKGTEAWERLRPFGDVVCLLRFPISL

Specific function: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has end

COG id: COG1537

COG function: function code R; Predicted RNA-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic release factor 1 family. Pelota subfamily

Homologues:

Organism=Homo sapiens, GI31880783, Length=371, Percent_Identity=25.6064690026954, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17554648, Length=362, Percent_Identity=24.585635359116, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324327, Length=361, Percent_Identity=23.2686980609418, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI17136914, Length=364, Percent_Identity=24.7252747252747, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PELO_IGNH4 (A8A935)

Other databases:

- EMBL:   CP000816
- RefSeq:   YP_001434844.1
- ProteinModelPortal:   A8A935
- SMR:   A8A935
- STRING:   A8A935
- GeneID:   5561839
- GenomeReviews:   CP000816_GR
- KEGG:   iho:Igni_0253
- eggNOG:   arNOG04486
- HOGENOM:   HBG646058
- OMA:   MKLVRKD
- BioCyc:   IHOS453591:IGNI_0253-MONOMER
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_01853
- InterPro:   IPR005140
- InterPro:   IPR005141
- InterPro:   IPR005142
- InterPro:   IPR004405
- PANTHER:   PTHR10853
- TIGRFAMs:   TIGR00111

Pfam domain/function: PF03463 eRF1_1; PF03464 eRF1_2; PF03465 eRF1_3

EC number: NA

Molecular weight: Translated: 37928; Mature: 37928

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLEVNESKGEVKVRVEDEEDVWILHSALRPGDLVRARTARSVAGSSGKEKIPMTLTIK
CEEEEECCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEE
VTGSEFQAFSNVLRVKGVVVEGPDKFGLIGSHHAIKVYPGKEITIIRERGLAQLLERLKK
EECHHHHHHHHHHHHCEEEEECCCCCCCCCCCCEEEEECCCEEEEEHHCCHHHHHHHHHC
GEERKPQVPVLAVDYDEYSLAVVRGQGIEWVFEGSLRLPGKGDEGREAATERKINELAKR
CCCCCCCCCEEEEECCCEEEEEEECCCEEEEEECCEECCCCCCCCHHHHHHHHHHHHHHH
VSEELKLRNLDHVVVVGPGFLKDKVAQRLSEEGFKVKVDSASSGGRAGVLEAIRKGSLRG
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCHHH
VAKELESIKALEALEEFVKHVARGDGYALYGVDDCMTAAQANAVKTLIISDDLLHSPDLG
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCEEEEEEECCCCCCCCCH
ERAVELVELAEKKGAEVIIVPKGTEAWERLRPFGDVVCLLRFPISL
HHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MRVLEVNESKGEVKVRVEDEEDVWILHSALRPGDLVRARTARSVAGSSGKEKIPMTLTIK
CEEEEECCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEE
VTGSEFQAFSNVLRVKGVVVEGPDKFGLIGSHHAIKVYPGKEITIIRERGLAQLLERLKK
EECHHHHHHHHHHHHCEEEEECCCCCCCCCCCCEEEEECCCEEEEEHHCCHHHHHHHHHC
GEERKPQVPVLAVDYDEYSLAVVRGQGIEWVFEGSLRLPGKGDEGREAATERKINELAKR
CCCCCCCCCEEEEECCCEEEEEEECCCEEEEEECCEECCCCCCCCHHHHHHHHHHHHHHH
VSEELKLRNLDHVVVVGPGFLKDKVAQRLSEEGFKVKVDSASSGGRAGVLEAIRKGSLRG
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCHHH
VAKELESIKALEALEEFVKHVARGDGYALYGVDDCMTAAQANAVKTLIISDDLLHSPDLG
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCEEEEEEECCCCCCCCCH
ERAVELVELAEKKGAEVIIVPKGTEAWERLRPFGDVVCLLRFPISL
HHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA