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The map label for this gene is gpt [H]

Identifier: 156937028

GI number: 156937028

Start: 204061

End: 204654

Strand: Reverse

Name: gpt [H]

Synonym: Igni_0233

Alternate gene names: 156937028

Gene position: 204654-204061 (Counterclockwise)

Preceding gene: 156937029

Following gene: 156937027

Centisome position: 15.77

GC content: 57.07

Gene sequence:

>594_bases
ATGACTCGGAGGGTCAGGGGTAGGGCACAAACCCTCCCACTCCTCACGCTTGAGGGCCCCCGGATGTACGAAGTCGTGAG
TTGGGAAGAAGTCCACAAGATGAGTTTGGAGTTGGCAAAGGCGATCGGCGATTCGGTGGACGCAGTGGTGGGTCTCTTAA
GGGGAGGCTACGTCCCGGCCCACCTAATAGCAGATGCCTTGGGCTTGGAATTGTACGTCATGAGAATCAAGAGTTACAGA
GGGATAGGGAAGAAGGGCAAACCGGTCGTCACGCTGCCGCTCATTGGCAACGTGACGGACTTGAGAATCCTCTTAGTGGA
CGACGTGTGCGACTCCGGCGAGACCTTGAGCGTCGCTAAGAAGTTCCTCGAGGCTTACTCCCCCAAGTCAATAACTACCG
CAGTTTTGTTCAAAAAACCTCAGTGCTCGGAGGAGGTTGATCTCTGGGTCAAGGAGAGCGGGAACTGGATCGTCTTCCCG
TGGGACGCGTCTGAAACGCTCAGAGAGGACCCCAGCGTTAAGGGCGCCCTAGAGGAGGCCTTGGGGGTCGAGCTTGATAT
TCTGGGGGAAGGCGGAGGTTCCGGAGAGGCCTAG

Upstream 100 bases:

>100_bases
CTACGAAGCGCTCCTCAAATGATTTTTAAATAACGCGAGGGCCAGCCTACGGGGACCGGCCCTACCAAAGAGAACTCCGA
GGAGGCCGGTGCACCGGGCG

Downstream 100 bases:

>100_bases
GCACGCCTACGGCACCGACCCGGTGAGGCTGAGGGCCGCCGCTGCCTTAGCTTACGACGACTTTGTTAAAGGATGCACGA
TCTCCAGCTATTTCCCCGTA

Product: phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTRRVRGRAQTLPLLTLEGPRMYEVVSWEEVHKMSLELAKAIGDSVDAVVGLLRGGYVPAHLIADALGLELYVMRIKSYR
GIGKKGKPVVTLPLIGNVTDLRILLVDDVCDSGETLSVAKKFLEAYSPKSITTAVLFKKPQCSEEVDLWVKESGNWIVFP
WDASETLREDPSVKGALEEALGVELDILGEGGGSGEA

Sequences:

>Translated_197_residues
MTRRVRGRAQTLPLLTLEGPRMYEVVSWEEVHKMSLELAKAIGDSVDAVVGLLRGGYVPAHLIADALGLELYVMRIKSYR
GIGKKGKPVVTLPLIGNVTDLRILLVDDVCDSGETLSVAKKFLEAYSPKSITTAVLFKKPQCSEEVDLWVKESGNWIVFP
WDASETLREDPSVKGALEEALGVELDILGEGGGSGEA
>Mature_196_residues
TRRVRGRAQTLPLLTLEGPRMYEVVSWEEVHKMSLELAKAIGDSVDAVVGLLRGGYVPAHLIADALGLELYVMRIKSYRG
IGKKGKPVVTLPLIGNVTDLRILLVDDVCDSGETLSVAKKFLEAYSPKSITTAVLFKKPQCSEEVDLWVKESGNWIVFPW
DASETLREDPSVKGALEEALGVELDILGEGGGSGEA

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG2236

COG function: function code R; Predicted phosphoribosyltransferases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 21423; Mature: 21292

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRVRGRAQTLPLLTLEGPRMYEVVSWEEVHKMSLELAKAIGDSVDAVVGLLRGGYVPA
CCCCCCCCCCCCCEEEECCCCEEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHH
HLIADALGLELYVMRIKSYRGIGKKGKPVVTLPLIGNVTDLRILLVDDVCDSGETLSVAK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCHHHHHH
KFLEAYSPKSITTAVLFKKPQCSEEVDLWVKESGNWIVFPWDASETLREDPSVKGALEEA
HHHHHCCCCCCEEEEEEECCCCCCCCEEEEECCCCEEEEECCCHHHHHCCCCHHHHHHHH
LGVELDILGEGGGSGEA
HCCEEEEEECCCCCCCC
>Mature Secondary Structure 
TRRVRGRAQTLPLLTLEGPRMYEVVSWEEVHKMSLELAKAIGDSVDAVVGLLRGGYVPA
CCCCCCCCCCCCEEEECCCCEEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHH
HLIADALGLELYVMRIKSYRGIGKKGKPVVTLPLIGNVTDLRILLVDDVCDSGETLSVAK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCHHHHHH
KFLEAYSPKSITTAVLFKKPQCSEEVDLWVKESGNWIVFPWDASETLREDPSVKGALEEA
HHHHHCCCCCCEEEEEEECCCCCCCCEEEEECCCCEEEEECCCHHHHHCCCCHHHHHHHH
LGVELDILGEGGGSGEA
HCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA