| Definition | Xanthobacter autotrophicus Py2 chromosome, complete genome. |
|---|---|
| Accession | NC_009720 |
| Length | 5,308,934 |
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The map label for this gene is hppA
Identifier: 154248117
GI number: 154248117
Start: 4645587
End: 4647728
Strand: Direct
Name: hppA
Synonym: Xaut_4197
Alternate gene names: 154248117
Gene position: 4645587-4647728 (Clockwise)
Preceding gene: 154248116
Following gene: 154248119
Centisome position: 87.51
GC content: 67.74
Gene sequence:
>2142_bases ATGTTGGCACTGGTGTTGATCATCGCCTGCGGCCTGCTGGCCGTGGCGTACGGCGTATGGGCCATCCGCGAACTCATGGC CGCGGATCCCGGTACCGCGCGGATGCAGGAAATCGCAGCCGCCATCGCGGAAGGGGCGCAGGCCTATCTGAAGCGCCAAT ACACCACCATCGGCGTGGTGGGCGTCGTCATCTTCGTTCTCGTGGGGGTGTTCCTCGGCTGGCTGGTGGCGGTGGGCTTC GCCGTCGGGGCGATCCTGTCGGCGCTGGCCGGCTTCATCGGCATGAACGTGTCGGTCCGCGCCAACGTGCGCACCGCGCA GGCGGCGACCCTGTCGCTGGCCGGCGGCCTCGATCTCGCGTTCAAGGCCGGGGCGGTCACCGGCCTGCTGGTGGCGGGCC TCGCCCTCCTCGGGGTCACGGTCTATTTCCTCGTGCTCACCCAGATCCTCGGCTTTGCCGGCAACAGCCGCACGGTGGTG GATGCGCTGGTGGCGCTGGGCTTCGGCGCCTCGCTCATCTCCATCTTTGCCCGTCTCGGCGGTGGCATCTTCACCAAGGG CGCCGACGTGGGCGGCGATCTCGTGGGCAAGGTGGAAGCCGGAATTCCGGAGGATGACCCGCGCAACCCGGCCACCATCG CCGACAACGTGGGCGACAATGTCGGCGACTGCGCCGGCATGGCCGCCGACCTGTTCGAGACCTATGCGGTGACCGTGGTG GCCACCATGGTGCTCGCCGCCATCTTCTTCGCTGCCGCGCCGGCGTCGCTCGCCACCATGATGGTCTATCCGCTGGCCAT CGGCGGGGCGTGCATCATCACCTCCATCGCCGGCACCTTCTTCGTGCGGCTCGGGGCCAATTCCTCGATCATGGGAGCGC TCTACAAGGGCCTCATGGCGACAGCGGGCTTCTCCATCATCGCGCTAGCTGCGGTGACGTGGCTTTTGCCCGGCTTCGGC CCCATCGCCGGGGCGGACTTCACCGGCACCAGCCTGTTCCTGTGCGGCCTCGTGGGCCTCGCGGTGACCGGCGCCATCGT GGTGATCACCGAATATTACACCGGCACCGGCTATCGCCCGGTGGTGTCCATCGCCCAGGCCTCGGTGACCGGGCACGGCA CCAACATCATCCAGGGCCTTGCCGTCTCGTTGGAATCCACGGCACTGCCGACGCTGGTCATCATCGCCGGCATCCTGTTC GCCTATGGCCTCGCCGGCCTGTTCGGCATCGCCATCGCCGCCACCACCATGCTGGCGCTGGCCGGCATGATCGTGGCGCT GGACGCCTTCGGCCCGGTCACGGACAACGCCGGCGGCATCGCCGAGATGGCCGGCCTGCCCAAGGAGGTGCGCCAGTCCA CCGACGCGCTGGACGCGGTGGGCAACACCACCAAAGCTGTCACCAAGGGCTATGCCATCGGCTCCGCCGGCCTCGGCGCG CTTGTGTTGTTCGCCGCCTACAGCCAGGACCTGAAGTACTTCATCGCCCAGGCGGGGCAGGGCACCTACTTCTATGGCGT GACCCCCAACTTCTCGCTTGAGAACCCCTATGTGGTGGTGGGCCTGCTGTTTGGCGGCCTGCTGCCGTTCCTGTTCGCCG CCATGGGCATGACGGCGGTGGGCCGGGCCGCTGGCGCCATCGTGGAGGAGGTGCGCCGGCAGTTCCGCGAGAAGCCGGGC ATCATGGCCGGCACCGAGAAGCCGGATTATTCCCGCGCCGTGGACATGCTGACCAAGGCGGCCATCAAGGAGATGATCAT CCCCTCCCTGCTGCCGGTGCTGTCGCCCATTGTCTGCTACTTCGTCATCTACTTCGTGGCGGGCGGCGGCGCGGCGGGGA AATCCGCCGCCTTCTCGGCGGTGGGCGCCATGCTGCTGGGCGTGATCGTGACCGGCCTCTTCGTCGCCATCTCCATGACC TCGGGCGGCGGCGCCTGGGACAATGCCAAGAAGTCGTTCGAGGACGGTTTCGTGGACAAGGACGGCGTGCGCCACATGAA GGGCTCGGAGGCCCACAAGGCCTCGGTGACCGGCGACACCGTGGGCGACCCCTACAAGGACACGGCGGGCCCCGCCGTGA ACCCCATGATCAAGATCACCAACATCGTGGCGCTGCTGCTACTGGCGGTGCTGGGGCATTGA
Upstream 100 bases:
>100_bases CTGCGACAGTTTGCCCGGACGCCCCTTGCCGTGGCGCACGGCACCGCTCACACTCGCCCCATAAAAGAATACAGGCAGGA AACGAAAAAGGGTGGGAGTG
Downstream 100 bases:
>100_bases GGGAAGACGCCGGCGGGCCAGACCTGCCCGCCGGCACCCCTATTTCCCGTCGCCGAAATCCACCACCTCGTTGTTCAGGG GCAGCGCGTCCTGCCTGGGG
Product: membrane-bound proton-translocating pyrophosphatase
Products: NA
Alternate protein names: Membrane-bound proton-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; H(+)-PPase [H]
Number of amino acids: Translated: 713; Mature: 713
Protein sequence:
>713_residues MLALVLIIACGLLAVAYGVWAIRELMAADPGTARMQEIAAAIAEGAQAYLKRQYTTIGVVGVVIFVLVGVFLGWLVAVGF AVGAILSALAGFIGMNVSVRANVRTAQAATLSLAGGLDLAFKAGAVTGLLVAGLALLGVTVYFLVLTQILGFAGNSRTVV DALVALGFGASLISIFARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVV ATMVLAAIFFAAAPASLATMMVYPLAIGGACIITSIAGTFFVRLGANSSIMGALYKGLMATAGFSIIALAAVTWLLPGFG PIAGADFTGTSLFLCGLVGLAVTGAIVVITEYYTGTGYRPVVSIAQASVTGHGTNIIQGLAVSLESTALPTLVIIAGILF AYGLAGLFGIAIAATTMLALAGMIVALDAFGPVTDNAGGIAEMAGLPKEVRQSTDALDAVGNTTKAVTKGYAIGSAGLGA LVLFAAYSQDLKYFIAQAGQGTYFYGVTPNFSLENPYVVVGLLFGGLLPFLFAAMGMTAVGRAAGAIVEEVRRQFREKPG IMAGTEKPDYSRAVDMLTKAAIKEMIIPSLLPVLSPIVCYFVIYFVAGGGAAGKSAAFSAVGAMLLGVIVTGLFVAISMT SGGGAWDNAKKSFEDGFVDKDGVRHMKGSEAHKASVTGDTVGDPYKDTAGPAVNPMIKITNIVALLLLAVLGH
Sequences:
>Translated_713_residues MLALVLIIACGLLAVAYGVWAIRELMAADPGTARMQEIAAAIAEGAQAYLKRQYTTIGVVGVVIFVLVGVFLGWLVAVGF AVGAILSALAGFIGMNVSVRANVRTAQAATLSLAGGLDLAFKAGAVTGLLVAGLALLGVTVYFLVLTQILGFAGNSRTVV DALVALGFGASLISIFARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVV ATMVLAAIFFAAAPASLATMMVYPLAIGGACIITSIAGTFFVRLGANSSIMGALYKGLMATAGFSIIALAAVTWLLPGFG PIAGADFTGTSLFLCGLVGLAVTGAIVVITEYYTGTGYRPVVSIAQASVTGHGTNIIQGLAVSLESTALPTLVIIAGILF AYGLAGLFGIAIAATTMLALAGMIVALDAFGPVTDNAGGIAEMAGLPKEVRQSTDALDAVGNTTKAVTKGYAIGSAGLGA LVLFAAYSQDLKYFIAQAGQGTYFYGVTPNFSLENPYVVVGLLFGGLLPFLFAAMGMTAVGRAAGAIVEEVRRQFREKPG IMAGTEKPDYSRAVDMLTKAAIKEMIIPSLLPVLSPIVCYFVIYFVAGGGAAGKSAAFSAVGAMLLGVIVTGLFVAISMT SGGGAWDNAKKSFEDGFVDKDGVRHMKGSEAHKASVTGDTVGDPYKDTAGPAVNPMIKITNIVALLLLAVLGH >Mature_713_residues MLALVLIIACGLLAVAYGVWAIRELMAADPGTARMQEIAAAIAEGAQAYLKRQYTTIGVVGVVIFVLVGVFLGWLVAVGF AVGAILSALAGFIGMNVSVRANVRTAQAATLSLAGGLDLAFKAGAVTGLLVAGLALLGVTVYFLVLTQILGFAGNSRTVV DALVALGFGASLISIFARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVV ATMVLAAIFFAAAPASLATMMVYPLAIGGACIITSIAGTFFVRLGANSSIMGALYKGLMATAGFSIIALAAVTWLLPGFG PIAGADFTGTSLFLCGLVGLAVTGAIVVITEYYTGTGYRPVVSIAQASVTGHGTNIIQGLAVSLESTALPTLVIIAGILF AYGLAGLFGIAIAATTMLALAGMIVALDAFGPVTDNAGGIAEMAGLPKEVRQSTDALDAVGNTTKAVTKGYAIGSAGLGA LVLFAAYSQDLKYFIAQAGQGTYFYGVTPNFSLENPYVVVGLLFGGLLPFLFAAMGMTAVGRAAGAIVEEVRRQFREKPG IMAGTEKPDYSRAVDMLTKAAIKEMIIPSLLPVLSPIVCYFVIYFVAGGGAAGKSAAFSAVGAMLLGVIVTGLFVAISMT SGGGAWDNAKKSFEDGFVDKDGVRHMKGSEAHKASVTGDTVGDPYKDTAGPAVNPMIKITNIVALLLLAVLGH
Specific function: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force [H]
COG id: COG3808
COG function: function code C; Inorganic pyrophosphatase
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004131 [H]
Pfam domain/function: PF03030 H_PPase [H]
EC number: =3.6.1.1 [H]
Molecular weight: Translated: 72336; Mature: 72336
Theoretical pI: Translated: 5.27; Mature: 5.27
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLALVLIIACGLLAVAYGVWAIRELMAADPGTARMQEIAAAIAEGAQAYLKRQYTTIGVV CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH GVVIFVLVGVFLGWLVAVGFAVGAILSALAGFIGMNVSVRANVRTAQAATLSLAGGLDLA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCHH FKAGAVTGLLVAGLALLGVTVYFLVLTQILGFAGNSRTVVDALVALGFGASLISIFARLG HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHC GGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVV CCEEECCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH ATMVLAAIFFAAAPASLATMMVYPLAIGGACIITSIAGTFFVRLGANSSIMGALYKGLMA HHHHHHHHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHH TAGFSIIALAAVTWLLPGFGPIAGADFTGTSLFLCGLVGLAVTGAIVVITEYYTGTGYRP HCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEHHCCCCCHH VVSIAQASVTGHGTNIIQGLAVSLESTALPTLVIIAGILFAYGLAGLFGIAIAATTMLAL HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH AGMIVALDAFGPVTDNAGGIAEMAGLPKEVRQSTDALDAVGNTTKAVTKGYAIGSAGLGA HHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHH LVLFAAYSQDLKYFIAQAGQGTYFYGVTPNFSLENPYVVVGLLFGGLLPFLFAAMGMTAV HHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH GRAAGAIVEEVRRQFREKPGIMAGTEKPDYSRAVDMLTKAAIKEMIIPSLLPVLSPIVCY HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH FVIYFVAGGGAAGKSAAFSAVGAMLLGVIVTGLFVAISMTSGGGAWDNAKKSFEDGFVDK HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCC DGVRHMKGSEAHKASVTGDTVGDPYKDTAGPAVNPMIKITNIVALLLLAVLGH CCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC >Mature Secondary Structure MLALVLIIACGLLAVAYGVWAIRELMAADPGTARMQEIAAAIAEGAQAYLKRQYTTIGVV CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH GVVIFVLVGVFLGWLVAVGFAVGAILSALAGFIGMNVSVRANVRTAQAATLSLAGGLDLA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCHH FKAGAVTGLLVAGLALLGVTVYFLVLTQILGFAGNSRTVVDALVALGFGASLISIFARLG HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHC GGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVV CCEEECCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH ATMVLAAIFFAAAPASLATMMVYPLAIGGACIITSIAGTFFVRLGANSSIMGALYKGLMA HHHHHHHHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHH TAGFSIIALAAVTWLLPGFGPIAGADFTGTSLFLCGLVGLAVTGAIVVITEYYTGTGYRP HCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEHHCCCCCHH VVSIAQASVTGHGTNIIQGLAVSLESTALPTLVIIAGILFAYGLAGLFGIAIAATTMLAL HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH AGMIVALDAFGPVTDNAGGIAEMAGLPKEVRQSTDALDAVGNTTKAVTKGYAIGSAGLGA HHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHH LVLFAAYSQDLKYFIAQAGQGTYFYGVTPNFSLENPYVVVGLLFGGLLPFLFAAMGMTAV HHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH GRAAGAIVEEVRRQFREKPGIMAGTEKPDYSRAVDMLTKAAIKEMIIPSLLPVLSPIVCY HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH FVIYFVAGGGAAGKSAAFSAVGAMLLGVIVTGLFVAISMTSGGGAWDNAKKSFEDGFVDK HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCC DGVRHMKGSEAHKASVTGDTVGDPYKDTAGPAVNPMIKITNIVALLLLAVLGH CCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 12597275 [H]