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The map label for this gene is acpS

Identifier: 154247802

GI number: 154247802

Start: 4298687

End: 4299094

Strand: Direct

Name: acpS

Synonym: Xaut_3879

Alternate gene names: 154247802

Gene position: 4298687-4299094 (Clockwise)

Preceding gene: 154247801

Following gene: 154247803

Centisome position: 80.97

GC content: 68.63

Gene sequence:

>408_bases
ATGATCATCGGCATCGGCTCGGACTTCTCGGACGCCCGGCGCATCGCCCGCTCCATCGAGCGGTTCGGCGACCGGTTCCT
CGACCGGGTGTTCACGCCTGGAGAGCGGCGCAAGGCGGATCAGCGCAAGCTGCGCGCCGAGACCTACGCCAAGCGCTTTG
CTGCCAAGGAAGCCTGCTCCAAGGCGCTGGGCACCGGCCTCAGCCACGGCGTGTTCTGGCGCGACATGGAGGTGGTGAAC
CTGCCGTCCGGCCAGCCGACCCTGATGCTCACCGGAGGCGCCGCCCGCCGCCTCGCCGCGCTGGTGCCGGACGGCTATGA
GCCGCACATCCATCTGTCCCTTACCGACGAGGGGCCGCTGACAGCGGCCTATGTGATCATATCGGCGGTACCCAAGACGG
GCGTGTGA

Upstream 100 bases:

>100_bases
TCATCGGCGAGGCCATTTTCGTGGGGCTCGACCAGGCCATTGCGCGCATGAGGGCGGCCATCGCGGCGGGCCGGGCCGCC
GTCGGGGACGGCGCGGCGGC

Downstream 100 bases:

>100_bases
CCCAGCGGGAGGCGCCGGGACGTGCGTTGCCGGGAGCCGACGAAGCCTCTATAGGGGCCATCAAGCGACCTTGGCCCTGT
GGACACGGGCGCCGATCCGG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MIIGIGSDFSDARRIARSIERFGDRFLDRVFTPGERRKADQRKLRAETYAKRFAAKEACSKALGTGLSHGVFWRDMEVVN
LPSGQPTLMLTGGAARRLAALVPDGYEPHIHLSLTDEGPLTAAYVIISAVPKTGV

Sequences:

>Translated_135_residues
MIIGIGSDFSDARRIARSIERFGDRFLDRVFTPGERRKADQRKLRAETYAKRFAAKEACSKALGTGLSHGVFWRDMEVVN
LPSGQPTLMLTGGAARRLAALVPDGYEPHIHLSLTDEGPLTAAYVIISAVPKTGV
>Mature_135_residues
MIIGIGSDFSDARRIARSIERFGDRFLDRVFTPGERRKADQRKLRAETYAKRFAAKEACSKALGTGLSHGVFWRDMEVVN
LPSGQPTLMLTGGAARRLAALVPDGYEPHIHLSLTDEGPLTAAYVIISAVPKTGV

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=128, Percent_Identity=35.9375, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_XANP2 (A7IM60)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001418760.1
- ProteinModelPortal:   A7IM60
- SMR:   A7IM60
- STRING:   A7IM60
- GeneID:   5421464
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_3879
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- ProtClustDB:   PRK00070
- BioCyc:   XAUT78245:XAUT_3879-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14756; Mature: 14756

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGIGSDFSDARRIARSIERFGDRFLDRVFTPGERRKADQRKLRAETYAKRFAAKEACS
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGLSHGVFWRDMEVVNLPSGQPTLMLTGGAARRLAALVPDGYEPHIHLSLTDEGPL
HHHHCCCCCCEEECCEEEEECCCCCCEEEEECCHHHHHHHHCCCCCCCEEEEEECCCCCH
TAAYVIISAVPKTGV
HHHHHHHHHCCCCCC
>Mature Secondary Structure
MIIGIGSDFSDARRIARSIERFGDRFLDRVFTPGERRKADQRKLRAETYAKRFAAKEACS
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGLSHGVFWRDMEVVNLPSGQPTLMLTGGAARRLAALVPDGYEPHIHLSLTDEGPL
HHHHCCCCCCEEECCEEEEECCCCCCEEEEECCHHHHHHHHCCCCCCCEEEEEECCCCCH
TAAYVIISAVPKTGV
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA