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The map label for this gene is cycW [H]

Identifier: 154247777

GI number: 154247777

Start: 4272492

End: 4273163

Strand: Direct

Name: cycW [H]

Synonym: Xaut_3854

Alternate gene names: 154247777

Gene position: 4272492-4273163 (Clockwise)

Preceding gene: 154247776

Following gene: 154247782

Centisome position: 80.48

GC content: 73.51

Gene sequence:

>672_bases
ATGATGGCCGCCTTTTTCGCCATCGTGCGGCGCGACCTCGCCTTGTCCCTCGGCTCCGGCGGCGGGGCGGGGCTGGGGGT
GGTGTTCTTCCTCAGCGTGGTCACGGTGGTGCCGTTCGCGGTGGGGCCGGATCTGGTGCTGCTGGCGCGCATCGGCCCGG
CCATCCTGTGGATCGGCGCCTTGCTCGCGAGCCTCATCGGCCTGGAGCGCCTGTTCGCGTCCGATGCGGAGGACGGCTCG
CTGGATGCGCTCACCCTGTCCGCCCTGCCGCTGGAACTGGCGGCGGCGGCCAAGGGCCTGGCTCACTGGCTCGCCACCGG
CCTGCCGCTGGTGCTCGCCGCCCCGGTGCTGGCGCTGATGCTGAATCTGGAGCCCGCCGCCATCGGCGCGGTGGTGCTGA
CCCTGCTGGTGGGAACCCCCGCGGTCACCTTCCTCGGGCTCATCGGCGCGGCCTTTGCCGGCGCGTTCCGGCGCGGCGGG
CTGCTGATCGCGGTGCTGGTGATTCCCCTCGCCATTCCGGTGCTGATCTTCGCCGTATCGGCGACGCAGGCGGCGGTGGT
GGGGCCGGTGCCGTTCGGCACGCCGTTCCGCGTGCTGCTGGGGCTCACCCTGTTCGCGCTGGTGCTGGGGCCGGTGGCGG
CCGCCGCCGCGCTCAGGGCGGCGCGATCCTGA

Upstream 100 bases:

>100_bases
CCGGCGCCATCTCGCCCCCGCTCCCGCTTGCGGGGGAGGGCTGGGGAGGGGGCAACGGCAGAGAGGCCCGCACCACCTCC
ACCTTCAGGAGCCTTCGCCC

Downstream 100 bases:

>100_bases
GCGCCGACGGCTGCTGAGGCGCGGACCTATTCCGCCGCGGTGCTGAGGGCGGAAAGCTCGGCCTCCAGCGCCGCCACCTG
CTGGCGGGTGGCCTCGGTGG

Product: heme exporter protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycW [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MMAAFFAIVRRDLALSLGSGGGAGLGVVFFLSVVTVVPFAVGPDLVLLARIGPAILWIGALLASLIGLERLFASDAEDGS
LDALTLSALPLELAAAAKGLAHWLATGLPLVLAAPVLALMLNLEPAAIGAVVLTLLVGTPAVTFLGLIGAAFAGAFRRGG
LLIAVLVIPLAIPVLIFAVSATQAAVVGPVPFGTPFRVLLGLTLFALVLGPVAAAAALRAARS

Sequences:

>Translated_223_residues
MMAAFFAIVRRDLALSLGSGGGAGLGVVFFLSVVTVVPFAVGPDLVLLARIGPAILWIGALLASLIGLERLFASDAEDGS
LDALTLSALPLELAAAAKGLAHWLATGLPLVLAAPVLALMLNLEPAAIGAVVLTLLVGTPAVTFLGLIGAAFAGAFRRGG
LLIAVLVIPLAIPVLIFAVSATQAAVVGPVPFGTPFRVLLGLTLFALVLGPVAAAAALRAARS
>Mature_223_residues
MMAAFFAIVRRDLALSLGSGGGAGLGVVFFLSVVTVVPFAVGPDLVLLARIGPAILWIGALLASLIGLERLFASDAEDGS
LDALTLSALPLELAAAAKGLAHWLATGLPLVLAAPVLALMLNLEPAAIGAVVLTLLVGTPAVTFLGLIGAAFAGAFRRGG
LLIAVLVIPLAIPVLIFAVSATQAAVVGPVPFGTPFRVLLGLTLFALVLGPVAAAAALRAARS

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=215, Percent_Identity=43.2558139534884, Blast_Score=117, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 22252; Mature: 22252

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAAFFAIVRRDLALSLGSGGGAGLGVVFFLSVVTVVPFAVGPDLVLLARIGPAILWIGA
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LLASLIGLERLFASDAEDGSLDALTLSALPLELAAAAKGLAHWLATGLPLVLAAPVLALM
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LNLEPAAIGAVVLTLLVGTPAVTFLGLIGAAFAGAFRRGGLLIAVLVIPLAIPVLIFAVS
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ATQAAVVGPVPFGTPFRVLLGLTLFALVLGPVAAAAALRAARS
HHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMAAFFAIVRRDLALSLGSGGGAGLGVVFFLSVVTVVPFAVGPDLVLLARIGPAILWIGA
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LLASLIGLERLFASDAEDGSLDALTLSALPLELAAAAKGLAHWLATGLPLVLAAPVLALM
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LNLEPAAIGAVVLTLLVGTPAVTFLGLIGAAFAGAFRRGGLLIAVLVIPLAIPVLIFAVS
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ATQAAVVGPVPFGTPFRVLLGLTLFALVLGPVAAAAALRAARS
HHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]