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The map label for this gene is 154247756

Identifier: 154247756

GI number: 154247756

Start: 4252690

End: 4253094

Strand: Direct

Name: 154247756

Synonym: Xaut_3833

Alternate gene names: NA

Gene position: 4252690-4253094 (Clockwise)

Preceding gene: 154247755

Following gene: 154247757

Centisome position: 80.1

GC content: 70.12

Gene sequence:

>405_bases
TTGGCCGGCAAGATCGCCTTCGATCACTGCGTGGTCCATGTGAGCGATTTCGCGCGCTCCAACGCCTTCTATGCGGCCGT
GCTGGGGGCCGAGGTGGTGCCGGCGGGGGCGGGCTTCGCCTATCGCTTCGGCGACCGCCAGCTGAACCTGCACGGGCCGG
GGGTGGACCCGGTTCCGGTGGCGCGACTACCGGTCCAGCCCGGCAACAGCGACCTGTGCTTCCGCTGGAGCGGGCCGATT
GCCGAGGCGGCGGCCCACCTTGCCGCCCATGGCATCACAGCGGAACTGGGCCCGGTGCCGCGCTTCGGCGCGCTGGGGCG
GGGCACCAGCCTCTATTTCCGCGATCCCGACGGATCGCTCCTGGAATTCATCTCCTATGACGACGCGCCGGGGGAGCAGC
CATGA

Upstream 100 bases:

>100_bases
AAGCGCGAGGCCTCCAAGGAACGCGACTGGGCGCGCGACAAGGCGCGCCTGATGCGCGACCGTGGCTGATCGGGCGGGGA
GCGGGCAAGGGGAGGGGGAG

Downstream 100 bases:

>100_bases
CCACCTATAACAGCCTGCCCGACAGCCTCCCCGCGCCGGAGGATGACGGTCACGCCGCCCACCTGCCGGGGCTGGAACTG
CCCATCATCCAGCTGCCGGC

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MAGKIAFDHCVVHVSDFARSNAFYAAVLGAEVVPAGAGFAYRFGDRQLNLHGPGVDPVPVARLPVQPGNSDLCFRWSGPI
AEAAAHLAAHGITAELGPVPRFGALGRGTSLYFRDPDGSLLEFISYDDAPGEQP

Sequences:

>Translated_134_residues
MAGKIAFDHCVVHVSDFARSNAFYAAVLGAEVVPAGAGFAYRFGDRQLNLHGPGVDPVPVARLPVQPGNSDLCFRWSGPI
AEAAAHLAAHGITAELGPVPRFGALGRGTSLYFRDPDGSLLEFISYDDAPGEQP
>Mature_133_residues
AGKIAFDHCVVHVSDFARSNAFYAAVLGAEVVPAGAGFAYRFGDRQLNLHGPGVDPVPVARLPVQPGNSDLCFRWSGPIA
EAAAHLAAHGITAELGPVPRFGALGRGTSLYFRDPDGSLLEFISYDDAPGEQP

Specific function: Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidogly

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI254039722, Length=121, Percent_Identity=41.3223140495868, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 14090; Mature: 13959

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGKIAFDHCVVHVSDFARSNAFYAAVLGAEVVPAGAGFAYRFGDRQLNLHGPGVDPVPV
CCCCEEHHHEEEEEHHHHCCCCEEEEEECCEEECCCCCEEEEECCCEEEEECCCCCCCCE
ARLPVQPGNSDLCFRWSGPIAEAAAHLAAHGITAELGPVPRFGALGRGTSLYFRDPDGSL
EEEECCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCE
LEFISYDDAPGEQP
EEEEECCCCCCCCC
>Mature Secondary Structure 
AGKIAFDHCVVHVSDFARSNAFYAAVLGAEVVPAGAGFAYRFGDRQLNLHGPGVDPVPV
CCCEEHHHEEEEEHHHHCCCCEEEEEECCEEECCCCCEEEEECCCEEEEECCCCCCCCE
ARLPVQPGNSDLCFRWSGPIAEAAAHLAAHGITAELGPVPRFGALGRGTSLYFRDPDGSL
EEEECCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCE
LEFISYDDAPGEQP
EEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]