Click here to switch to the map view.

The map label for this gene is dnaA [H]

Identifier: 154247623

GI number: 154247623

Start: 4099369

End: 4099956

Strand: Direct

Name: dnaA [H]

Synonym: Xaut_3697

Alternate gene names: 154247623

Gene position: 4099369-4099956 (Clockwise)

Preceding gene: 154247622

Following gene: 154247624

Centisome position: 77.22

GC content: 59.86

Gene sequence:

>588_bases
GTGAACATGCACATTAACCGGGAAGAACCTCAGAGGCAGCATCGGGAACACAAGCTGAGGCAAGAGCGTCTTGGCGGTAT
GGCGCGCCGGAAGGAATGGCTTCGTTTGCTCGATGAGCCCGCTGACGTTCCTGCCCCGACTCCCGCTCCCGTCCCCGTTG
CAGCTATCGCGCCCGCACCTGAGCCTGAGCCGGTATCCTACCATGATCACGGCTTCGACCTTCACGTCTCCGCATGGCGC
GAAGCTATGTGGGAAAAGCCGCAGGTCGATATGAGGCCGACGGTAGGCAAGATCATTGCCACGGTATGCGAGTTCTACGG
CATCCCGAAGGTCGAGTTGCTTGCTCACCGCCGCCTCAAGTCATTCGCGAAAGCGCGTCAGGTTGCGATGTACCTGTCGC
GGGAGCTTACGACGAAGTCTCTTCCTGTGATCGGGGCAGCAATTGGCGGCCGAGACCATACCACGATACTACACGGGGTC
GGAAAGATTTCGGCGGAGATTGAGACTAACGCGCGCCTCGCCTCCGAAGTCGAAACCATCCGCCTTAAGCTGATCGGAGG
CGACGATGCCGACGCCACAGGAGCTTGA

Upstream 100 bases:

>100_bases
ATCCCAATATCAAGGACGGCTTTGCCGCTACAGAGCCCAGCCGCTCTGTCCCGCTTCGCTCTCTTCCGGCCACTATCTTC
TCTTCTACGGGGGTGATGTC

Downstream 100 bases:

>100_bases
GAGCGCAGCCAAAGCTATCGAGGACGCATGGCGCCTTCTGGAGCGCGGCGAGAAGCTGAAGAAGTCAGCGAAGGACTACC
TCGGGCCTCGTGTCGTTGAT

Product: chromosomal replication initiator DnaA domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MNMHINREEPQRQHREHKLRQERLGGMARRKEWLRLLDEPADVPAPTPAPVPVAAIAPAPEPEPVSYHDHGFDLHVSAWR
EAMWEKPQVDMRPTVGKIIATVCEFYGIPKVELLAHRRLKSFAKARQVAMYLSRELTTKSLPVIGAAIGGRDHTTILHGV
GKISAEIETNARLASEVETIRLKLIGGDDADATGA

Sequences:

>Translated_195_residues
MNMHINREEPQRQHREHKLRQERLGGMARRKEWLRLLDEPADVPAPTPAPVPVAAIAPAPEPEPVSYHDHGFDLHVSAWR
EAMWEKPQVDMRPTVGKIIATVCEFYGIPKVELLAHRRLKSFAKARQVAMYLSRELTTKSLPVIGAAIGGRDHTTILHGV
GKISAEIETNARLASEVETIRLKLIGGDDADATGA
>Mature_195_residues
MNMHINREEPQRQHREHKLRQERLGGMARRKEWLRLLDEPADVPAPTPAPVPVAAIAPAPEPEPVSYHDHGFDLHVSAWR
EAMWEKPQVDMRPTVGKIIATVCEFYGIPKVELLAHRRLKSFAKARQVAMYLSRELTTKSLPVIGAAIGGRDHTTILHGV
GKISAEIETNARLASEVETIRLKLIGGDDADATGA

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=70, Percent_Identity=54.2857142857143, Blast_Score=78, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 21694; Mature: 21694

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMHINREEPQRQHREHKLRQERLGGMARRKEWLRLLDEPADVPAPTPAPVPVAAIAPAP
CCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCC
EPEPVSYHDHGFDLHVSAWREAMWEKPQVDMRPTVGKIIATVCEFYGIPKVELLAHRRLK
CCCCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
SFAKARQVAMYLSRELTTKSLPVIGAAIGGRDHTTILHGVGKISAEIETNARLASEVETI
HHHHHHHHHHHHHHHHHHCCCCCEEHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHEEE
RLKLIGGDDADATGA
EEEEECCCCCCCCCC
>Mature Secondary Structure
MNMHINREEPQRQHREHKLRQERLGGMARRKEWLRLLDEPADVPAPTPAPVPVAAIAPAP
CCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCC
EPEPVSYHDHGFDLHVSAWREAMWEKPQVDMRPTVGKIIATVCEFYGIPKVELLAHRRLK
CCCCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
SFAKARQVAMYLSRELTTKSLPVIGAAIGGRDHTTILHGVGKISAEIETNARLASEVETI
HHHHHHHHHHHHHHHHHHCCCCCEEHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHEEE
RLKLIGGDDADATGA
EEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA