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The map label for this gene is syrD [H]

Identifier: 154246727

GI number: 154246727

Start: 3098758

End: 3100503

Strand: Reverse

Name: syrD [H]

Synonym: Xaut_2788

Alternate gene names: 154246727

Gene position: 3100503-3098758 (Counterclockwise)

Preceding gene: 154246731

Following gene: 154246726

Centisome position: 58.4

GC content: 70.1

Gene sequence:

>1746_bases
ATGGGCCCGTCACCCGCGCCCGTCGCCGCGGACGCTGCCAACGCCGCATCGCGGCCCCCGCAGGAGAGCGGCTTCTCGCT
TCTGGGCTTCGTGTTCGGGCAGAACCCGGTGGAATTCTCCACCGCCGTGGCCACCAGCCTGCTGAGCGGCGTCGCCGCTG
TCGCCCTGATCATCCTCATCAACATGGCGCTGGCCTCCGACGGGTCGGACCTTGCGACACTGGGCCTCGTCTTCGCGGCG
GTCGCGGTGGTGACGGTGGCGCTGCAGACGGCGTCCGGCATCCTGTTCGGCCGGCTCGGGCAAGAGGTGCTGGCCCGCCT
GCGCAGCCGCATCGCCGAGCGGGTGGAAGCCGCGCCCCTGCGCGCGGTGGAGCAGGTGGGGCCGGCGCGGCTGCAGGCCC
TCATCACCGACGATGTGTTCACCCTCGCCACCGTGGTGGTGCGGCTGCCGGTGCTGTTCACCAATGCCGTCGCCATCTCC
GGCTGCCTCTTCTATCTCGCCTGGCTGTCCCTGCCGCTGTTTGTCGGCGCGGCGGGGATGATGGCGCTGGGAGTTGCCGG
CTACATGCTGGTGGCGAGGCGGGCGCGACATCATCTGGAGCATGCGGGCGGGCGGCAGGACACGCTGTTTGCCCACCTGT
CGGCGCTGGTGCTCGGCACCAAAGAGCTGAAGCTCAACCGCGCCAAGGCCGAGGATTTCCGCACCCGCCATCTGGGCGCC
GCCATCGAGACCGTGCGGCGCGCTCGCACCCACGGCATCACCCTGCTGGCGCTCGGCTCCGCCTGGGGCAGCCTGATCGT
GTTCGGCTTCATCGGCCTCGTGCTGTTCGTGTTCACCGGCGGCGGCACGGTGGCCACCGGCTATGCGGTGGTGCTGCTGT
TCCTCATCGGGCCGCTCGCCGCCGTGATGGAGGACCTGCCCCGGCTGGCGGTCGCCCGCGTCGCCGGCCAGCGCCTTGCC
GAAACCGAGGCGGCCCTTGCCACCCGCGACACGGAGCCGGCCCCGCCCGCGCCGTTCGCGAGCCTCGCCTTCGAGGCCGT
CACCCACGCCTATTGGGACGAGCGGACGGCGGAGATGTTCCGCCTCGGCCCCGTGGACATCGCCTTCGCGCCGGGGGAAA
TCGTGTTTCTGGTGGGCGGCAACGGCTCCGGCAAGACCACCCTTGCCAAGCTCGTCACCGGCCTCTACGCGCCGGAGAGC
GGCACGGTGCGGCTCAATGGCGCCATCGTCGACGATACCAGCCGGAGCACGCAGCGCGCCCTGTTCTCAGCCGTGTTCGG
CGACTTCCACCTGTTCGAGAGCCTGATCGGCCTGTCAGGGGCGCCGGACCTCGACGCCCGCGCCAACCGGCTGATCTCGC
GGCTCGCCCTGACCCACAAGGTGAGCGTGGATGACGGGCACTTCTCCACCCGCGATCTCTCCACCGGCCAGCGCAAGCGC
CTCGCCCTCGTCGCCGCCGTGCTGGAGGACCGCCCCTTCCTGGTGTTCGACGAATGGGCGGCAGACCAGGACCCTGCCTT
CAAGGGCGTATTCTACCGCGAGCTGCTGCCGGAGCTGAAGGCGCTGGGCAAGAGCGTGCTCGTGATCTCCCACGACGACC
GCTATTTCGATTGCGGCGACCGCATCGTGCACATGGAGAACGGGCAGATCACCGGCGATGCGCGCACCGGCGCCGACGAT
GATGCGCGGCGCGAGGACCCTAAATTTCCCGAGCCCTCGTTCGTCTTCCAGTCGACCCCCATTTGA

Upstream 100 bases:

>100_bases
GTCCGGGCTCCAGACCTTAAGTTTGGAGGGCGATTCACCGCGCAAATTGATTCAATTTGCCGGGCTCGCGCTCCAAAGCC
ATCGAGGGAGCCGAACACAC

Downstream 100 bases:

>100_bases
GGCCCCCACTTACGGCCCGGCGCACCCACCCATCGGCAGGGCGCCGGCCATGATCCGCCCGGACGGGTGCGAAGGTTGCC
ATGGCATTCGATGACGAGAA

Product: cyclic peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 580

Protein sequence:

>581_residues
MGPSPAPVAADAANAASRPPQESGFSLLGFVFGQNPVEFSTAVATSLLSGVAAVALIILINMALASDGSDLATLGLVFAA
VAVVTVALQTASGILFGRLGQEVLARLRSRIAERVEAAPLRAVEQVGPARLQALITDDVFTLATVVVRLPVLFTNAVAIS
GCLFYLAWLSLPLFVGAAGMMALGVAGYMLVARRARHHLEHAGGRQDTLFAHLSALVLGTKELKLNRAKAEDFRTRHLGA
AIETVRRARTHGITLLALGSAWGSLIVFGFIGLVLFVFTGGGTVATGYAVVLLFLIGPLAAVMEDLPRLAVARVAGQRLA
ETEAALATRDTEPAPPAPFASLAFEAVTHAYWDERTAEMFRLGPVDIAFAPGEIVFLVGGNGSGKTTLAKLVTGLYAPES
GTVRLNGAIVDDTSRSTQRALFSAVFGDFHLFESLIGLSGAPDLDARANRLISRLALTHKVSVDDGHFSTRDLSTGQRKR
LALVAAVLEDRPFLVFDEWAADQDPAFKGVFYRELLPELKALGKSVLVISHDDRYFDCGDRIVHMENGQITGDARTGADD
DARREDPKFPEPSFVFQSTPI

Sequences:

>Translated_581_residues
MGPSPAPVAADAANAASRPPQESGFSLLGFVFGQNPVEFSTAVATSLLSGVAAVALIILINMALASDGSDLATLGLVFAA
VAVVTVALQTASGILFGRLGQEVLARLRSRIAERVEAAPLRAVEQVGPARLQALITDDVFTLATVVVRLPVLFTNAVAIS
GCLFYLAWLSLPLFVGAAGMMALGVAGYMLVARRARHHLEHAGGRQDTLFAHLSALVLGTKELKLNRAKAEDFRTRHLGA
AIETVRRARTHGITLLALGSAWGSLIVFGFIGLVLFVFTGGGTVATGYAVVLLFLIGPLAAVMEDLPRLAVARVAGQRLA
ETEAALATRDTEPAPPAPFASLAFEAVTHAYWDERTAEMFRLGPVDIAFAPGEIVFLVGGNGSGKTTLAKLVTGLYAPES
GTVRLNGAIVDDTSRSTQRALFSAVFGDFHLFESLIGLSGAPDLDARANRLISRLALTHKVSVDDGHFSTRDLSTGQRKR
LALVAAVLEDRPFLVFDEWAADQDPAFKGVFYRELLPELKALGKSVLVISHDDRYFDCGDRIVHMENGQITGDARTGADD
DARREDPKFPEPSFVFQSTPI
>Mature_580_residues
GPSPAPVAADAANAASRPPQESGFSLLGFVFGQNPVEFSTAVATSLLSGVAAVALIILINMALASDGSDLATLGLVFAAV
AVVTVALQTASGILFGRLGQEVLARLRSRIAERVEAAPLRAVEQVGPARLQALITDDVFTLATVVVRLPVLFTNAVAISG
CLFYLAWLSLPLFVGAAGMMALGVAGYMLVARRARHHLEHAGGRQDTLFAHLSALVLGTKELKLNRAKAEDFRTRHLGAA
IETVRRARTHGITLLALGSAWGSLIVFGFIGLVLFVFTGGGTVATGYAVVLLFLIGPLAAVMEDLPRLAVARVAGQRLAE
TEAALATRDTEPAPPAPFASLAFEAVTHAYWDERTAEMFRLGPVDIAFAPGEIVFLVGGNGSGKTTLAKLVTGLYAPESG
TVRLNGAIVDDTSRSTQRALFSAVFGDFHLFESLIGLSGAPDLDARANRLISRLALTHKVSVDDGHFSTRDLSTGQRKRL
ALVAAVLEDRPFLVFDEWAADQDPAFKGVFYRELLPELKALGKSVLVISHDDRYFDCGDRIVHMENGQITGDARTGADDD
ARREDPKFPEPSFVFQSTPI

Specific function: ATP-driven efflux pump necessary for the secretion of syringomycin. May specifically bind syringomycin and translocate it to the periplasmic space. SyrD is also required for full expression of the syrB gene [H]

COG id: COG4615

COG function: function code QP; ABC-type siderophore export system, fused ATPase and permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI42490749, Length=394, Percent_Identity=24.1116751269036, Blast_Score=66, Evalue=1e-10,
Organism=Escherichia coli, GI1788540, Length=552, Percent_Identity=35.8695652173913, Blast_Score=295, Evalue=8e-81,
Organism=Escherichia coli, GI1788225, Length=211, Percent_Identity=30.8056872037915, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787112, Length=418, Percent_Identity=25.1196172248804, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1786253, Length=169, Percent_Identity=30.1775147928994, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081834, Length=218, Percent_Identity=27.0642201834862, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789032, Length=223, Percent_Identity=28.2511210762332, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787029, Length=207, Percent_Identity=25.6038647342995, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1786654, Length=503, Percent_Identity=23.0616302186879, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787089, Length=208, Percent_Identity=29.3269230769231, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789873, Length=208, Percent_Identity=27.8846153846154, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787105, Length=199, Percent_Identity=26.6331658291457, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI87081782, Length=219, Percent_Identity=28.310502283105, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI48995001, Length=211, Percent_Identity=26.0663507109005, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786872, Length=207, Percent_Identity=28.5024154589372, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71996550, Length=174, Percent_Identity=31.6091954022989, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17565938, Length=229, Percent_Identity=27.0742358078603, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115535101, Length=223, Percent_Identity=28.6995515695067, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193208177, Length=340, Percent_Identity=25.2941176470588, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567265, Length=282, Percent_Identity=27.3049645390071, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24666092, Length=231, Percent_Identity=28.1385281385281, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641565, Length=234, Percent_Identity=29.4871794871795, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363262, Length=257, Percent_Identity=27.2373540856031, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24653245, Length=257, Percent_Identity=27.2373540856031, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593
- InterPro:   IPR005898 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 61721; Mature: 61590

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50893 ABC_TRANSPORTER_2 ; PS50929 ABC_TM1F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPSPAPVAADAANAASRPPQESGFSLLGFVFGQNPVEFSTAVATSLLSGVAAVALIILI
CCCCCCCCCCCCHHCCCCCCCCCCCCEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NMALASDGSDLATLGLVFAAVAVVTVALQTASGILFGRLGQEVLARLRSRIAERVEAAPL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAVEQVGPARLQALITDDVFTLATVVVRLPVLFTNAVAISGCLFYLAWLSLPLFVGAAGM
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MALGVAGYMLVARRARHHLEHAGGRQDTLFAHLSALVLGTKELKLNRAKAEDFRTRHLGA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
AIETVRRARTHGITLLALGSAWGSLIVFGFIGLVLFVFTGGGTVATGYAVVLLFLIGPLA
HHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AVMEDLPRLAVARVAGQRLAETEAALATRDTEPAPPAPFASLAFEAVTHAYWDERTAEMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RLGPVDIAFAPGEIVFLVGGNGSGKTTLAKLVTGLYAPESGTVRLNGAIVDDTSRSTQRA
CCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEECCEEECCCCHHHHHH
LFSAVFGDFHLFESLIGLSGAPDLDARANRLISRLALTHKVSVDDGHFSTRDLSTGQRKR
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHH
LALVAAVLEDRPFLVFDEWAADQDPAFKGVFYRELLPELKALGKSVLVISHDDRYFDCGD
HHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCC
RIVHMENGQITGDARTGADDDARREDPKFPEPSFVFQSTPI
EEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GPSPAPVAADAANAASRPPQESGFSLLGFVFGQNPVEFSTAVATSLLSGVAAVALIILI
CCCCCCCCCCCHHCCCCCCCCCCCCEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NMALASDGSDLATLGLVFAAVAVVTVALQTASGILFGRLGQEVLARLRSRIAERVEAAPL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAVEQVGPARLQALITDDVFTLATVVVRLPVLFTNAVAISGCLFYLAWLSLPLFVGAAGM
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MALGVAGYMLVARRARHHLEHAGGRQDTLFAHLSALVLGTKELKLNRAKAEDFRTRHLGA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
AIETVRRARTHGITLLALGSAWGSLIVFGFIGLVLFVFTGGGTVATGYAVVLLFLIGPLA
HHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AVMEDLPRLAVARVAGQRLAETEAALATRDTEPAPPAPFASLAFEAVTHAYWDERTAEMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RLGPVDIAFAPGEIVFLVGGNGSGKTTLAKLVTGLYAPESGTVRLNGAIVDDTSRSTQRA
CCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEECCEEECCCCHHHHHH
LFSAVFGDFHLFESLIGLSGAPDLDARANRLISRLALTHKVSVDDGHFSTRDLSTGQRKR
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHH
LALVAAVLEDRPFLVFDEWAADQDPAFKGVFYRELLPELKALGKSVLVISHDDRYFDCGD
HHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCC
RIVHMENGQITGDARTGADDDARREDPKFPEPSFVFQSTPI
EEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8231810 [H]