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The map label for this gene is lpsI [H]

Identifier: 154246291

GI number: 154246291

Start: 2623117

End: 2623830

Strand: Direct

Name: lpsI [H]

Synonym: Xaut_2349

Alternate gene names: 154246291

Gene position: 2623117-2623830 (Clockwise)

Preceding gene: 154246290

Following gene: 154246292

Centisome position: 49.41

GC content: 62.75

Gene sequence:

>714_bases
ATGCGACACAAGGTGTACCCGGACGCGAAAAGTGCCCTGGAGGGCGTCCTCGCCGACGGCATGATGATCATGGCCGGCGG
CTTCGGCCTCTGCGGCATCCCCGAGAACCTCATCGCCGCCATCCGCGACCTTGGCGCGAAGAACCTCACCTGCGTGTCCA
ACAATTGCGGTGTGGACGATTTCGGCCTCGGCATCCTCCTCGCCAACGGCCAGATCAAGAAGATGCTGTCGTCCTATGTG
GGCGAGAACAAGCTGTTCGAGAAGCTGTATCTCGCCGGCGAGCTGGAGCTGGAGTTCAACCCGCAGGGCACCCTGGCCGA
GCGCATCCGCGCCGGCGGCGCCGGCATTCCCGGCTTCTACACCAAGACCGGCTACGGCACGATCATCGCCGAGGGCAAGC
CCACCCGCGAGTTCAACGGCGAGCATTATGTGCTGGAGACGGGCCTGGTTGCGGACCTTTCCATCATCAAGGCGTGGAAG
GCCGACAAGGAAGGCAATCTCATCTACCGCAAGACCGCCCGGAACTTCAATCCGATGATGGCCACGGCCGGCAAGGTGAC
CATTGCCGAGGTTGAGGAGCTGGTGGAAATCGGCGATCTCGACCCGGACAGCATCCACACCCCCGGCATCTATGTGGACC
GCATCGTCGTCAGCAAAGGCGCCGAGAAGCGGATCGAGAAGGTGACCACCCGCAAGCGCGAAGAGGTGAAGTGA

Upstream 100 bases:

>100_bases
CCTGTGACGGCGCGGCGGCGCGCGATTCCGCTCGGTCCCGCTTCCGCTTGAGGGACCGGCCTCTTAAGGTCATCGAGGCG
CCAGCGCCGAGGAGGAAATG

Downstream 100 bases:

>100_bases
GATGGCCTGGACCCGTGACGAGATGGCGGCCCGCGCCGCCCAGCAGATCCGCGACGGCTTCTACGTCAACCTCGGCATCG
GCATCCCCACCCTGGTCGCC

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MRHKVYPDAKSALEGVLADGMMIMAGGFGLCGIPENLIAAIRDLGAKNLTCVSNNCGVDDFGLGILLANGQIKKMLSSYV
GENKLFEKLYLAGELELEFNPQGTLAERIRAGGAGIPGFYTKTGYGTIIAEGKPTREFNGEHYVLETGLVADLSIIKAWK
ADKEGNLIYRKTARNFNPMMATAGKVTIAEVEELVEIGDLDPDSIHTPGIYVDRIVVSKGAEKRIEKVTTRKREEVK

Sequences:

>Translated_237_residues
MRHKVYPDAKSALEGVLADGMMIMAGGFGLCGIPENLIAAIRDLGAKNLTCVSNNCGVDDFGLGILLANGQIKKMLSSYV
GENKLFEKLYLAGELELEFNPQGTLAERIRAGGAGIPGFYTKTGYGTIIAEGKPTREFNGEHYVLETGLVADLSIIKAWK
ADKEGNLIYRKTARNFNPMMATAGKVTIAEVEELVEIGDLDPDSIHTPGIYVDRIVVSKGAEKRIEKVTTRKREEVK
>Mature_237_residues
MRHKVYPDAKSALEGVLADGMMIMAGGFGLCGIPENLIAAIRDLGAKNLTCVSNNCGVDDFGLGILLANGQIKKMLSSYV
GENKLFEKLYLAGELELEFNPQGTLAERIRAGGAGIPGFYTKTGYGTIIAEGKPTREFNGEHYVLETGLVADLSIIKAWK
ADKEGNLIYRKTARNFNPMMATAGKVTIAEVEELVEIGDLDPDSIHTPGIYVDRIVVSKGAEKRIEKVTTRKREEVK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=250, Percent_Identity=54.8, Blast_Score=276, Evalue=8e-75,
Organism=Homo sapiens, GI11545841, Length=253, Percent_Identity=52.1739130434783, Blast_Score=256, Evalue=1e-68,
Organism=Escherichia coli, GI1788551, Length=205, Percent_Identity=44.8780487804878, Blast_Score=193, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17531517, Length=247, Percent_Identity=53.4412955465587, Blast_Score=256, Evalue=5e-69,
Organism=Drosophila melanogaster, GI21358325, Length=243, Percent_Identity=51.440329218107, Blast_Score=249, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24655794, Length=243, Percent_Identity=51.440329218107, Blast_Score=249, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25739; Mature: 25739

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHKVYPDAKSALEGVLADGMMIMAGGFGLCGIPENLIAAIRDLGAKNLTCVSNNCGVDD
CCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCC
FGLGILLANGQIKKMLSSYVGENKLFEKLYLAGELELEFNPQGTLAERIRAGGAGIPGFY
CCCEEEEECCHHHHHHHHHHCCHHHHHHHHHEEEEEEEECCCCHHHHHHHCCCCCCCCCE
TKTGYGTIIAEGKPTREFNGEHYVLETGLVADLSIIKAWKADKEGNLIYRKTARNFNPMM
ECCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHH
ATAGKVTIAEVEELVEIGDLDPDSIHTPGIYVDRIVVSKGAEKRIEKVTTRKREEVK
HCCCCEEHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRHKVYPDAKSALEGVLADGMMIMAGGFGLCGIPENLIAAIRDLGAKNLTCVSNNCGVDD
CCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCC
FGLGILLANGQIKKMLSSYVGENKLFEKLYLAGELELEFNPQGTLAERIRAGGAGIPGFY
CCCEEEEECCHHHHHHHHHHCCHHHHHHHHHEEEEEEEECCCCHHHHHHHCCCCCCCCCE
TKTGYGTIIAEGKPTREFNGEHYVLETGLVADLSIIKAWKADKEGNLIYRKTARNFNPMM
ECCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHH
ATAGKVTIAEVEELVEIGDLDPDSIHTPGIYVDRIVVSKGAEKRIEKVTTRKREEVK
HCCCCEEHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]