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The map label for this gene is pgsA [H]

Identifier: 154246287

GI number: 154246287

Start: 2620684

End: 2621325

Strand: Direct

Name: pgsA [H]

Synonym: Xaut_2345

Alternate gene names: 154246287

Gene position: 2620684-2621325 (Clockwise)

Preceding gene: 154246286

Following gene: 154246288

Centisome position: 49.36

GC content: 69.0

Gene sequence:

>642_bases
ATGGCAGAGGCAGCGACCCGTTCCCCCACCTCATCCGCGCCCGAACGGGGCGGGCGGGGCCATGCGCTTTCGCTGCCGAA
TATCCTTACCTATTCGCGCTGCGTGGCGGTGCCGCTGGTGGCGGCCTGCCTGTTCTGGTCGGACATCCTGGAAGGCGGCG
CGGTGCTGCGCTGGGTGGCGCTGGCGCTCTACATCGCCGCCGCCATTACCGACTTCTTCGACGGCTATCTTGCCCGCGCG
TGGTCGCAGCAATCGGCCATCGGGCGGATGCTGGACCCCATCGCCGACAAGCTGCTGGTCTCCACCTGCCTGCTCATGCT
GGCGTCCGACGGCACCATCCGCGGCTGGTCCCTGTGGGCGGCCATCGTCATCCTGTGCCGGGAGATCCTGGTGTCCGGCC
TGCGCGAGTTCCTGGCCGAGCTGAGGGTTTCGGTGCCGGTGTCGCGCCTCGCCAAGTGGAAGACCACGCTCCAACTCGTC
GCCGTGGGCGTGCTCATCACCGGGCCGGCGGGGGAGAGCGTGCTGCCGGGGGTGAACCTCATCGGGCTCACGCTGCTGTG
GGTGTCGGCGGTGCTCACGCTGTACACGGGCTATGATTATTTCCGGGCCGGCGCCCGCCACCTGGTGGAGGACGAGCGGT
GA

Upstream 100 bases:

>100_bases
ACGGAGGCTTCCGCCTGCCGCCCGCGCAGCCTAAATAGAAGCCGTCCACCTCCCTCGGGATGTGAACGCACAGGCGGCAT
CCGACCGACGAAGAGACCCG

Downstream 100 bases:

>100_bases
AGATCCTGTATTTCGCCTGGCTGCGCGAGCGCGTCGGGCTCGCGGAGGAAGAGGTGGCGCCGCCCGCCGAGGTGGCCACC
GTGGCCGATCTCGCGCGTTG

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MAEAATRSPTSSAPERGGRGHALSLPNILTYSRCVAVPLVAACLFWSDILEGGAVLRWVALALYIAAAITDFFDGYLARA
WSQQSAIGRMLDPIADKLLVSTCLLMLASDGTIRGWSLWAAIVILCREILVSGLREFLAELRVSVPVSRLAKWKTTLQLV
AVGVLITGPAGESVLPGVNLIGLTLLWVSAVLTLYTGYDYFRAGARHLVEDER

Sequences:

>Translated_213_residues
MAEAATRSPTSSAPERGGRGHALSLPNILTYSRCVAVPLVAACLFWSDILEGGAVLRWVALALYIAAAITDFFDGYLARA
WSQQSAIGRMLDPIADKLLVSTCLLMLASDGTIRGWSLWAAIVILCREILVSGLREFLAELRVSVPVSRLAKWKTTLQLV
AVGVLITGPAGESVLPGVNLIGLTLLWVSAVLTLYTGYDYFRAGARHLVEDER
>Mature_212_residues
AEAATRSPTSSAPERGGRGHALSLPNILTYSRCVAVPLVAACLFWSDILEGGAVLRWVALALYIAAAITDFFDGYLARAW
SQQSAIGRMLDPIADKLLVSTCLLMLASDGTIRGWSLWAAIVILCREILVSGLREFLAELRVSVPVSRLAKWKTTLQLVA
VGVLITGPAGESVLPGVNLIGLTLLWVSAVLTLYTGYDYFRAGARHLVEDER

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=195, Percent_Identity=34.8717948717949, Blast_Score=100, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71984838, Length=208, Percent_Identity=26.9230769230769, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71984834, Length=208, Percent_Identity=26.9230769230769, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320059, Length=182, Percent_Identity=29.1208791208791, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22972; Mature: 22841

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEAATRSPTSSAPERGGRGHALSLPNILTYSRCVAVPLVAACLFWSDILEGGAVLRWVA
CCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LALYIAAAITDFFDGYLARAWSQQSAIGRMLDPIADKLLVSTCLLMLASDGTIRGWSLWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AIVILCREILVSGLREFLAELRVSVPVSRLAKWKTTLQLVAVGVLITGPAGESVLPGVNL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHH
IGLTLLWVSAVLTLYTGYDYFRAGARHLVEDER
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AEAATRSPTSSAPERGGRGHALSLPNILTYSRCVAVPLVAACLFWSDILEGGAVLRWVA
CCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LALYIAAAITDFFDGYLARAWSQQSAIGRMLDPIADKLLVSTCLLMLASDGTIRGWSLWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AIVILCREILVSGLREFLAELRVSVPVSRLAKWKTTLQLVAVGVLITGPAGESVLPGVNL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHH
IGLTLLWVSAVLTLYTGYDYFRAGARHLVEDER
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA