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The map label for this gene is hypE [H]

Identifier: 154246130

GI number: 154246130

Start: 2446339

End: 2447403

Strand: Direct

Name: hypE [H]

Synonym: Xaut_2187

Alternate gene names: 154246130

Gene position: 2446339-2447403 (Clockwise)

Preceding gene: 154246129

Following gene: 154246131

Centisome position: 46.08

GC content: 71.36

Gene sequence:

>1065_bases
ATGAACATCCCCGTCCTCCCCCCCACCCGGCGCCGGCCGCTGAGCCACAAGACCGTGACGCTCGCCCATGGCGGCGGCGG
CAGCGCCATGCGCGACCTCATCGACGACGTGTTCCTCGCCACCTTCTCCGGCGACGGCCGCGCCGCGCCCGAGGATCAGG
CCCGCTTCGACCTCGCCGCGCTGATGGCCCATGGCGACCGCCTCGCCTTCACCACCGACGGCTTCGTGGTGGACCCGCTG
TTCTTTCCCGGCGGCGACATCGGCAAGCTCGCGGTCTGCGGCACCGTGAATGACCTTGCGGTGGGCGGCGCGACGCCGAT
GGCGCTGTCCTGCGCCGTCATCATCGAGGAGGGCCTGCCGGTGGAGACCCTGCGGCAGGTGGCGGCCTCCATGGCTGAAA
CCGCGCGGGCGGCGGGCGTTGCCATCGCCACCGGCGATACCAAGGTGGTGGCGCGCGGGGCGTGCGACAAGCTCTTCATC
ACCACCACCGGCATCGGTGTGGTGCGCCGTGGGCTCGACGTGGGCATCGCCAGGGCGCGGCCCGGCGACGTGCTGCTGGT
GAACGGCCTTCTGGGCGACCACGGCGCCGCCATCCTGAATGCGCGGGGCGACCTTGCCCTTGAGACCGCCATCGAGAGCG
ATTGCGCGCCCCTGAACGGCCTCATCGACATACTGATCGCGGCCGCCCCCGGCATCCGCATGATGCGCGATGCCACCCGC
GGCGGCGTGGCGGCTGTGGTGAACGAACTGGCCGAGGCCAGCGCCGTGGGGGTGCGGCTGAAGGAGCTCAGCCTGCCCAT
GCGGGCCGAGGTGATGGGCTTCTGCGAGATCCTCGGCCTCGACCCGCTCTATCTTGCCAACGAGGGCAAGATCCTCGCCG
TGGTGCCGCCCGAGGAGGCCGACGCCGCGCTTGCGGCGCTGCGCGCCCATCCGCTGGGACGGGAGGCGGCCATCATCGGC
GAGGTCACGGCCCAGCGGCCCGGACGGGTGGTCATGCAAACGCGCTTCGGGGGAGAGCGCATCGTCGATATGCTGGTCGG
CGATCAATTGCCCCGCATCTGCTGA

Upstream 100 bases:

>100_bases
CCGGCTGCACCCCCGAGACGCCGCTGGGCGCGCTCATGGTGTCGTCCGAAGGCTCTTGCGCCGCCTATTACCAATATGGT
GGCGTGCGGGGAGAAGCCGC

Downstream 100 bases:

>100_bases
AACCTTCATTTGGGGAGAAGACTATGCGTTACACAGCCCGCACGGCCCTTGCCGTTGCAGCCTTTTCGGTCCTGCCGCAG
CTGGCCTTCGCCCATACGGG

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MNIPVLPPTRRRPLSHKTVTLAHGGGGSAMRDLIDDVFLATFSGDGRAAPEDQARFDLAALMAHGDRLAFTTDGFVVDPL
FFPGGDIGKLAVCGTVNDLAVGGATPMALSCAVIIEEGLPVETLRQVAASMAETARAAGVAIATGDTKVVARGACDKLFI
TTTGIGVVRRGLDVGIARARPGDVLLVNGLLGDHGAAILNARGDLALETAIESDCAPLNGLIDILIAAAPGIRMMRDATR
GGVAAVVNELAEASAVGVRLKELSLPMRAEVMGFCEILGLDPLYLANEGKILAVVPPEEADAALAALRAHPLGREAAIIG
EVTAQRPGRVVMQTRFGGERIVDMLVGDQLPRIC

Sequences:

>Translated_354_residues
MNIPVLPPTRRRPLSHKTVTLAHGGGGSAMRDLIDDVFLATFSGDGRAAPEDQARFDLAALMAHGDRLAFTTDGFVVDPL
FFPGGDIGKLAVCGTVNDLAVGGATPMALSCAVIIEEGLPVETLRQVAASMAETARAAGVAIATGDTKVVARGACDKLFI
TTTGIGVVRRGLDVGIARARPGDVLLVNGLLGDHGAAILNARGDLALETAIESDCAPLNGLIDILIAAAPGIRMMRDATR
GGVAAVVNELAEASAVGVRLKELSLPMRAEVMGFCEILGLDPLYLANEGKILAVVPPEEADAALAALRAHPLGREAAIIG
EVTAQRPGRVVMQTRFGGERIVDMLVGDQLPRIC
>Mature_354_residues
MNIPVLPPTRRRPLSHKTVTLAHGGGGSAMRDLIDDVFLATFSGDGRAAPEDQARFDLAALMAHGDRLAFTTDGFVVDPL
FFPGGDIGKLAVCGTVNDLAVGGATPMALSCAVIIEEGLPVETLRQVAASMAETARAAGVAIATGDTKVVARGACDKLFI
TTTGIGVVRRGLDVGIARARPGDVLLVNGLLGDHGAAILNARGDLALETAIESDCAPLNGLIDILIAAAPGIRMMRDATR
GGVAAVVNELAEASAVGVRLKELSLPMRAEVMGFCEILGLDPLYLANEGKILAVVPPEEADAALAALRAHPLGREAAIIG
EVTAQRPGRVVMQTRFGGERIVDMLVGDQLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=338, Percent_Identity=55.6213017751479, Blast_Score=353, Evalue=1e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36628; Mature: 36628

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIPVLPPTRRRPLSHKTVTLAHGGGGSAMRDLIDDVFLATFSGDGRAAPEDQARFDLAA
CCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHH
LMAHGDRLAFTTDGFVVDPLFFPGGDIGKLAVCGTVNDLAVGGATPMALSCAVIIEEGLP
HHHCCCEEEEEECCEEECCEECCCCCCCCEEEECCCHHHCCCCCCHHHHEEEEEEECCCC
VETLRQVAASMAETARAAGVAIATGDTKVVARGACDKLFITTTGIGVVRRGLDVGIARAR
HHHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCEEEEEECCHHHHHHCCCCCEECCC
PGDVLLVNGLLGDHGAAILNARGDLALETAIESDCAPLNGLIDILIAAAPGIRMMRDATR
CCCEEEEECCCCCCCCEEEECCCCEEEEHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHCC
GGVAAVVNELAEASAVGVRLKELSLPMRAEVMGFCEILGLDPLYLANEGKILAVVPPEEA
CCHHHHHHHHHHHHHHCEEHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCH
DAALAALRAHPLGREAAIIGEVTAQRPGRVVMQTRFGGERIVDMLVGDQLPRIC
HHHHHHHHCCCCCCCEEEEEHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNIPVLPPTRRRPLSHKTVTLAHGGGGSAMRDLIDDVFLATFSGDGRAAPEDQARFDLAA
CCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHH
LMAHGDRLAFTTDGFVVDPLFFPGGDIGKLAVCGTVNDLAVGGATPMALSCAVIIEEGLP
HHHCCCEEEEEECCEEECCEECCCCCCCCEEEECCCHHHCCCCCCHHHHEEEEEEECCCC
VETLRQVAASMAETARAAGVAIATGDTKVVARGACDKLFITTTGIGVVRRGLDVGIARAR
HHHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCEEEEEECCHHHHHHCCCCCEECCC
PGDVLLVNGLLGDHGAAILNARGDLALETAIESDCAPLNGLIDILIAAAPGIRMMRDATR
CCCEEEEECCCCCCCCEEEECCCCEEEEHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHCC
GGVAAVVNELAEASAVGVRLKELSLPMRAEVMGFCEILGLDPLYLANEGKILAVVPPEEA
CCHHHHHHHHHHHHHHCEEHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCH
DAALAALRAHPLGREAAIIGEVTAQRPGRVVMQTRFGGERIVDMLVGDQLPRIC
HHHHHHHHCCCCCCCEEEEEHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8497190 [H]