Click here to switch to the map view.

The map label for this gene is atpH

Identifier: 154246020

GI number: 154246020

Start: 2337258

End: 2337863

Strand: Direct

Name: atpH

Synonym: Xaut_2077

Alternate gene names: 154246020

Gene position: 2337258-2337863 (Clockwise)

Preceding gene: 154246019

Following gene: 154246021

Centisome position: 44.02

GC content: 64.19

Gene sequence:

>606_bases
ATGGCTGCGCAAGGCGCGCGGCATGGGCTGCAAGTTCGAGAGAGGTGCGGGGTGGCGGATACGATCGTGTCAGGCATGGC
GGGGCGCTACGCGACCGCGCTGTTCGAACTGGCGACAGAGGCCGGCGCCGTCGATTCCGTGAAGGCGGATCTCGATCGCT
TGTCGGCCCTTATTGCGGAGAGCGCGGATCTGGCGCGGCTGGTCAAAAGCCCGGTCTTTTCGGCCGAGGAGCAGCTGAAG
GCCATTTCGGCGGTACTTGATCAGGCGGGCATTTCCGGTCTCGCCGGAAATTTCGTGAGGCGGGTGGCGCAGAACCGTCG
CCTGTTCGCGTTGCCCCGCATGGTTGCCGACTATGCGTCCCTCGTCGCCGCCATGCGCGGTGAGACGACGGCGCAGGTCA
CGGTGCCGGCGCCCTTGAGCGATGCGCACTTCTTCGCGCTCAAGGACGCGTTGGCCCAGCAGACCGGCAAGGACGTGATT
CTCGACGTCACCGTCGATCCGTCCATCCTCGGTGGTCTCATCGTGAAGCTCGGCTCCCGCATGGTCGATGCCTCTCTCAA
GACCAAACTCAATTCTATCCGGCATGCGATGAAAGAGGTCCGCTGA

Upstream 100 bases:

>100_bases
CACTTCTGCCTGTGTTAGGCACACCGGGATTTCGAGAGGCGGGTTTAGCCCTCTCGCGGGGTCGCACTAGATTATTCCCA
ACAGATCAAGGGCTTGGGCA

Downstream 100 bases:

>100_bases
TGGACATTCGAGCCGCTGAAATCACCGCCATCCTCAAGGAGCAGATCCAGAACTTCGGCCAGGAGGCCGAGGTTTCCGAG
GTGGGTCAGGTTCTCTCCGT

Product: ATP synthase F1 subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MAAQGARHGLQVRERCGVADTIVSGMAGRYATALFELATEAGAVDSVKADLDRLSALIAESADLARLVKSPVFSAEEQLK
AISAVLDQAGISGLAGNFVRRVAQNRRLFALPRMVADYASLVAAMRGETTAQVTVPAPLSDAHFFALKDALAQQTGKDVI
LDVTVDPSILGGLIVKLGSRMVDASLKTKLNSIRHAMKEVR

Sequences:

>Translated_201_residues
MAAQGARHGLQVRERCGVADTIVSGMAGRYATALFELATEAGAVDSVKADLDRLSALIAESADLARLVKSPVFSAEEQLK
AISAVLDQAGISGLAGNFVRRVAQNRRLFALPRMVADYASLVAAMRGETTAQVTVPAPLSDAHFFALKDALAQQTGKDVI
LDVTVDPSILGGLIVKLGSRMVDASLKTKLNSIRHAMKEVR
>Mature_200_residues
AAQGARHGLQVRERCGVADTIVSGMAGRYATALFELATEAGAVDSVKADLDRLSALIAESADLARLVKSPVFSAEEQLKA
ISAVLDQAGISGLAGNFVRRVAQNRRLFALPRMVADYASLVAAMRGETTAQVTVPAPLSDAHFFALKDALAQQTGKDVIL
DVTVDPSILGGLIVKLGSRMVDASLKTKLNSIRHAMKEVR

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=180, Percent_Identity=32.2222222222222, Blast_Score=100, Evalue=9e-22,
Organism=Escherichia coli, GI1790173, Length=169, Percent_Identity=27.810650887574, Blast_Score=60, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71984710, Length=177, Percent_Identity=32.2033898305085, Blast_Score=104, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71984717, Length=177, Percent_Identity=32.2033898305085, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6320504, Length=180, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24647054, Length=171, Percent_Identity=33.9181286549708, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_XANP2 (A7IH28)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001416978.1
- ProteinModelPortal:   A7IH28
- SMR:   A7IH28
- STRING:   A7IH28
- GeneID:   5423183
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_2077
- eggNOG:   COG0712
- HOGENOM:   HBG668108
- OMA:   FIAICGE
- ProtClustDB:   CLSK979663
- BioCyc:   XAUT78245:XAUT_2077-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- InterPro:   IPR020781
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 21243; Mature: 21112

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAQGARHGLQVRERCGVADTIVSGMAGRYATALFELATEAGAVDSVKADLDRLSALIAE
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SADLARLVKSPVFSAEEQLKAISAVLDQAGISGLAGNFVRRVAQNRRLFALPRMVADYAS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LVAAMRGETTAQVTVPAPLSDAHFFALKDALAQQTGKDVILDVTVDPSILGGLIVKLGSR
HHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHH
MVDASLKTKLNSIRHAMKEVR
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AAQGARHGLQVRERCGVADTIVSGMAGRYATALFELATEAGAVDSVKADLDRLSALIAE
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SADLARLVKSPVFSAEEQLKAISAVLDQAGISGLAGNFVRRVAQNRRLFALPRMVADYAS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LVAAMRGETTAQVTVPAPLSDAHFFALKDALAQQTGKDVILDVTVDPSILGGLIVKLGSR
HHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHH
MVDASLKTKLNSIRHAMKEVR
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA