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The map label for this gene is rlmH

Identifier: 154246004

GI number: 154246004

Start: 2320004

End: 2320486

Strand: Direct

Name: rlmH

Synonym: Xaut_2061

Alternate gene names: 154246004

Gene position: 2320004-2320486 (Clockwise)

Preceding gene: 154246003

Following gene: 154246005

Centisome position: 43.7

GC content: 72.88

Gene sequence:

>483_bases
GTGCGCCTCGTCCTCGCCTGTGTCGGCCGGCTGAAAGCCGGGGCCGAGCGCGACCTCGTCACGCGCTATGTGGATCGCAT
CCGTCCCGCCGGACGTCCCTTGGGCCTCGGCCCCTGCGACATGATCGAAATTCCGGAATCCGCCGCCCGCCGTGCCGAGG
ACCGCATGGCGGAGGAGGGCGCGGCGCTGCTTGCGGCCCTGCCCGCCGGCGCGGGGCTGATCGCGCTCGACCCGCGCGGG
CGCCAGCTCTCCAGCGAGGATTTCGCGACGCGCATGGCGGCCCAGCGCGACGGCGGCCTGCCGGCGCTTGCCTTCATCAT
CGGCGGCGCGGACGGGCTCGCCGACGCGGTGCGGGACAAGGCAGCGCTCATGGTCGCCTACGGCACCGCCACCTTTCCCC
ACCAACTGGTGCGGGTGATGCTGGCGGAGCAGATCTACCGCGCCGTCACCATCCTTGCGGGCCATCCTTACCACCGGGCG
TGA

Upstream 100 bases:

>100_bases
CCACGTCTTCCAGCCCGAGGTCCGCAGCTTCTACAACATCGAGAAGATGTGGTCCGGGACGCGCCCCTGATGCGTTCCGG
GTCGGCTTGCTGAGAGCTGC

Downstream 100 bases:

>100_bases
GGCGATGGCGGCCCGCCTGCATTGACATCGGCGCCTTCGCCCCTTATCACGCCGGCTCGATCCAGCAACACGGTGTCGAA
ACGGGCCGCGCGGAAACGCG

Product: rRNA large subunit methyltransferase

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MRLVLACVGRLKAGAERDLVTRYVDRIRPAGRPLGLGPCDMIEIPESAARRAEDRMAEEGAALLAALPAGAGLIALDPRG
RQLSSEDFATRMAAQRDGGLPALAFIIGGADGLADAVRDKAALMVAYGTATFPHQLVRVMLAEQIYRAVTILAGHPYHRA

Sequences:

>Translated_160_residues
MRLVLACVGRLKAGAERDLVTRYVDRIRPAGRPLGLGPCDMIEIPESAARRAEDRMAEEGAALLAALPAGAGLIALDPRG
RQLSSEDFATRMAAQRDGGLPALAFIIGGADGLADAVRDKAALMVAYGTATFPHQLVRVMLAEQIYRAVTILAGHPYHRA
>Mature_160_residues
MRLVLACVGRLKAGAERDLVTRYVDRIRPAGRPLGLGPCDMIEIPESAARRAEDRMAEEGAALLAALPAGAGLIALDPRG
RQLSSEDFATRMAAQRDGGLPALAFIIGGADGLADAVRDKAALMVAYGTATFPHQLVRVMLAEQIYRAVTILAGHPYHRA

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=165, Percent_Identity=32.1212121212121, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_XANP2 (A7IH12)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001416962.1
- ProteinModelPortal:   A7IH12
- SMR:   A7IH12
- STRING:   A7IH12
- GeneID:   5423033
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_2061
- eggNOG:   COG1576
- HOGENOM:   HBG622807
- OMA:   ILSGHPY
- ProtClustDB:   PRK00103
- BioCyc:   XAUT78245:XAUT_2061-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 16986; Mature: 16986

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVLACVGRLKAGAERDLVTRYVDRIRPAGRPLGLGPCDMIEIPESAARRAEDRMAEEG
CHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHH
AALLAALPAGAGLIALDPRGRQLSSEDFATRMAAQRDGGLPALAFIIGGADGLADAVRDK
HHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEHHHHCCCHHHHHHHHHH
AALMVAYGTATFPHQLVRVMLAEQIYRAVTILAGHPYHRA
HHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRLVLACVGRLKAGAERDLVTRYVDRIRPAGRPLGLGPCDMIEIPESAARRAEDRMAEEG
CHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHH
AALLAALPAGAGLIALDPRGRQLSSEDFATRMAAQRDGGLPALAFIIGGADGLADAVRDK
HHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEHHHHCCCHHHHHHHHHH
AALMVAYGTATFPHQLVRVMLAEQIYRAVTILAGHPYHRA
HHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA