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The map label for this gene is obg

Identifier: 154245998

GI number: 154245998

Start: 2314070

End: 2315104

Strand: Direct

Name: obg

Synonym: Xaut_2055

Alternate gene names: 154245998

Gene position: 2314070-2315104 (Clockwise)

Preceding gene: 154245997

Following gene: 154245999

Centisome position: 43.59

GC content: 68.5

Gene sequence:

>1035_bases
ATGAAATTCCTCGATCAGGCCAAGGTCTATGTGCGCTCCGGCGACGGGGGGGCGGGTTGCGTCTCCTTCCGGCGCGAGAA
ATTCATCGAGTTCGGCGGTCCCGATGGCGGCGACGGCGGACGCGGCGGCGACGTGTGGATCGAGTGCGTGGATGGCCTCA
ACACGCTCATCGACTATCGCTACCAGCAGCATTTCAAGGCCAAGAAGGGCGACCACGGCAAGGGCGCCAACCGCACCGGC
GCCCGTGGCTCCGACGTGGTGCTGAGGGTGCCCGCCGGCACCCAGATCCTTGATGAGACGGAAGAGACGGTCCTTGCCGA
CCTCACCGAGGTGGGCCAGCGCATCAAGCTCTTGGAAGGCGGCAACGGCGGCTTCGGCAACGCCCAGTTCAAGACCTCGA
CCAACCAGGCCCCGCGCCGCGCCAATCCCGGCCTGGAAGGCCAGGAGCGGTGGATCTGGCTGCGCCTGAAGCTGATCGCC
GACGCCGGCCTCGTGGGCCTGCCCAATGCCGGCAAGTCCACCTTCCTCGCCGCTACCACCGCGGCCAAGCCCAAGATCGC
CGACTACCCCTTCACCACGCTGCATCCCGGCCTCGGGGTGGTGCGGGTGGACGGGCGCGAGTTCGTGCTCGCCGACATTC
CCGGCCTCATCGAGGGCGCGCACGAGGGGGTGGGCATCGGCGACCGCTTCCTCGGCCATGTGGAGCGCTGCCGGGCGCTG
CTGCATCTGGTGGACGGCACATCCGAGCACGCCGGCAAGGCCTACAAGACGGTGCGGGCCGAGCTTGCCGCCTATGGCAA
CGGCCTCGACGAGAAACCGGAGATCGTGGCCCTGTCCAAGGTGGATGCGCTCTCCCCCGAGCTGCTCAAGCAGCAGAAGG
AGCGCCTGAAGCGCGCCGCCAAGAAGACGCCGCTCTTGCTCTCGGCCCAGTCGGGGCAAGGGGTTCAGGAGGCGTTGCGC
CTGCTGCTTTCCGTGGTGGAAGAGGAGCGCGGCGCCGAGAAGGCGGAGGAACCGCGGGACGCCTGGCGGCCCTGA

Upstream 100 bases:

>100_bases
GTGCGCGCCAAGGTGTGCCACGCCAATGCCGAGCGCATCCTGAAGCTGTGAAGATGCGGCCGCCCTTGCGTTTGCGGCGC
CTCCCGTCTACCTCCAAGCC

Downstream 100 bases:

>100_bases
CGGGGTCGCGGCACCTCCCGGCGGGCTTGAACTTCGGCGACTCGATGGCCTATGCCGTCGCCGGGGCGCATGTCGCGCCG
CTTCTCTTCAAGGGGGATGA

Product: GTP-binding protein Obg/CgtA

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKFLDQAKVYVRSGDGGAGCVSFRREKFIEFGGPDGGDGGRGGDVWIECVDGLNTLIDYRYQQHFKAKKGDHGKGANRTG
ARGSDVVLRVPAGTQILDETEETVLADLTEVGQRIKLLEGGNGGFGNAQFKTSTNQAPRRANPGLEGQERWIWLRLKLIA
DAGLVGLPNAGKSTFLAATTAAKPKIADYPFTTLHPGLGVVRVDGREFVLADIPGLIEGAHEGVGIGDRFLGHVERCRAL
LHLVDGTSEHAGKAYKTVRAELAAYGNGLDEKPEIVALSKVDALSPELLKQQKERLKRAAKKTPLLLSAQSGQGVQEALR
LLLSVVEEERGAEKAEEPRDAWRP

Sequences:

>Translated_344_residues
MKFLDQAKVYVRSGDGGAGCVSFRREKFIEFGGPDGGDGGRGGDVWIECVDGLNTLIDYRYQQHFKAKKGDHGKGANRTG
ARGSDVVLRVPAGTQILDETEETVLADLTEVGQRIKLLEGGNGGFGNAQFKTSTNQAPRRANPGLEGQERWIWLRLKLIA
DAGLVGLPNAGKSTFLAATTAAKPKIADYPFTTLHPGLGVVRVDGREFVLADIPGLIEGAHEGVGIGDRFLGHVERCRAL
LHLVDGTSEHAGKAYKTVRAELAAYGNGLDEKPEIVALSKVDALSPELLKQQKERLKRAAKKTPLLLSAQSGQGVQEALR
LLLSVVEEERGAEKAEEPRDAWRP
>Mature_344_residues
MKFLDQAKVYVRSGDGGAGCVSFRREKFIEFGGPDGGDGGRGGDVWIECVDGLNTLIDYRYQQHFKAKKGDHGKGANRTG
ARGSDVVLRVPAGTQILDETEETVLADLTEVGQRIKLLEGGNGGFGNAQFKTSTNQAPRRANPGLEGQERWIWLRLKLIA
DAGLVGLPNAGKSTFLAATTAAKPKIADYPFTTLHPGLGVVRVDGREFVLADIPGLIEGAHEGVGIGDRFLGHVERCRAL
LHLVDGTSEHAGKAYKTVRAELAAYGNGLDEKPEIVALSKVDALSPELLKQQKERLKRAAKKTPLLLSAQSGQGVQEALR
LLLSVVEEERGAEKAEEPRDAWRP

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=321, Percent_Identity=40.1869158878505, Blast_Score=171, Evalue=7e-43,
Organism=Homo sapiens, GI111955139, Length=292, Percent_Identity=38.6986301369863, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI111955063, Length=126, Percent_Identity=45.2380952380952, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI4758796, Length=123, Percent_Identity=35.7723577235772, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI58761500, Length=98, Percent_Identity=35.7142857142857, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4557537, Length=117, Percent_Identity=34.1880341880342, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1789574, Length=346, Percent_Identity=47.6878612716763, Blast_Score=278, Evalue=4e-76,
Organism=Escherichia coli, GI1787454, Length=102, Percent_Identity=39.2156862745098, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=322, Percent_Identity=36.0248447204969, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17552324, Length=305, Percent_Identity=28.8524590163934, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17509631, Length=99, Percent_Identity=37.3737373737374, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17555344, Length=114, Percent_Identity=35.9649122807018, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71981008, Length=114, Percent_Identity=35.0877192982456, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=126, Percent_Identity=44.4444444444444, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6319281, Length=137, Percent_Identity=31.3868613138686, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321612, Length=113, Percent_Identity=36.283185840708, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20129375, Length=322, Percent_Identity=36.0248447204969, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24585318, Length=292, Percent_Identity=36.3013698630137, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24640873, Length=99, Percent_Identity=35.3535353535354, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640877, Length=99, Percent_Identity=35.3535353535354, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640875, Length=99, Percent_Identity=35.3535353535354, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17981711, Length=123, Percent_Identity=32.520325203252, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356473, Length=117, Percent_Identity=34.1880341880342, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_XANP2 (A7IH06)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001416956.1
- ProteinModelPortal:   A7IH06
- SMR:   A7IH06
- STRING:   A7IH06
- GeneID:   5423044
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_2055
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   ATCEHAG
- ProtClustDB:   PRK12299
- BioCyc:   XAUT78245:XAUT_2055-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 37065; Mature: 37065

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLDQAKVYVRSGDGGAGCVSFRREKFIEFGGPDGGDGGRGGDVWIECVDGLNTLIDYR
CCCHHCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YQQHFKAKKGDHGKGANRTGARGSDVVLRVPAGTQILDETEETVLADLTEVGQRIKLLEG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEEEEC
GNGGFGNAQFKTSTNQAPRRANPGLEGQERWIWLRLKLIADAGLVGLPNAGKSTFLAATT
CCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEECCCCCCCEEEEEEC
AAKPKIADYPFTTLHPGLGVVRVDGREFVLADIPGLIEGAHEGVGIGDRFLGHVERCRAL
CCCCCCCCCCCCEECCCCCEEEECCCEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHH
LHLVDGTSEHAGKAYKTVRAELAAYGNGLDEKPEIVALSKVDALSPELLKQQKERLKRAA
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECHHCCCCHHHHHHHHHHHHHHH
KKTPLLLSAQSGQGVQEALRLLLSVVEEERGAEKAEEPRDAWRP
HCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHCCCHHHCCC
>Mature Secondary Structure
MKFLDQAKVYVRSGDGGAGCVSFRREKFIEFGGPDGGDGGRGGDVWIECVDGLNTLIDYR
CCCHHCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YQQHFKAKKGDHGKGANRTGARGSDVVLRVPAGTQILDETEETVLADLTEVGQRIKLLEG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEEEEC
GNGGFGNAQFKTSTNQAPRRANPGLEGQERWIWLRLKLIADAGLVGLPNAGKSTFLAATT
CCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEECCCCCCCEEEEEEC
AAKPKIADYPFTTLHPGLGVVRVDGREFVLADIPGLIEGAHEGVGIGDRFLGHVERCRAL
CCCCCCCCCCCCEECCCCCEEEECCCEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHH
LHLVDGTSEHAGKAYKTVRAELAAYGNGLDEKPEIVALSKVDALSPELLKQQKERLKRAA
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECHHCCCCHHHHHHHHHHHHHHH
KKTPLLLSAQSGQGVQEALRLLLSVVEEERGAEKAEEPRDAWRP
HCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA