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The map label for this gene is tktB [C]

Identifier: 154245985

GI number: 154245985

Start: 2300186

End: 2301121

Strand: Reverse

Name: tktB [C]

Synonym: Xaut_2042

Alternate gene names: 154245985

Gene position: 2301121-2300186 (Counterclockwise)

Preceding gene: 154245986

Following gene: 154245984

Centisome position: 43.34

GC content: 69.02

Gene sequence:

>936_bases
GTGAGCTGCCGGTCCCGAGGACCGCCCAGACAGAGAGCCTTCATGAGCGCAGCCGAACGCACCCTGCCCCACGACGCGCG
GCACGCGTCCAATTTCCGTCCCACCGCCGAGACCCTTGCCCTGTTGCGGGAGAAGGCGCGCTTCGTGCGGCTGGAGACCA
TCCGGCTGATCGAGGTGGCGAAGGTCGGCCACTACAGCTCGGTGTTCTCCGCCGCCGAGATCTTCGCCGCCCTCTATTAC
GACGTGATGGACATCACCCACGGCGACCCGCGCCGGCCGGACCGCGACCGCTTCCTGATGGGCAAGGGCCACGCCGCCGT
GGGCCTGTTCCCCATCCTCGCCGAGCTCGGCTACATCGACCGCGAGACGCTGGACAACTACACCCGCCTCGGCAATCCGC
TGGGCGACCACCCGGACATGCGCAAGGTGCCCGGCATCGACTTCTCCTCCGGCTCCATCGGCCACGCCCTGTCAGCCGGC
CTCGGCATGGCGCTGGGCGGGCGGATGCAGGACCGCGCCTTCAACGTCTTCGTCATGCTCGGCGACGGCGAGATGCAGGA
GGGCCAGGTGTGGGAGGCGGCCATCTCGGCGGCCCACCACAAGGCCTCGAACCTCGTCGCCATCGTCGATCGCAACGGCT
TCCAGCTCGACGGGGCGGTGGACGACGTGATGGGCATCGAGCCGCTGGACGAGAAATGGCGCGCCTTCGGCTGGGAGGTC
CACACCGTGGACGGCCACGACCTCGACGCCCTCACCACCCTCCTCCGGCAGGTGAAGGCGGATGAGGGGCGCACCCGGCC
CTGCTGCATCATCGCCCGCACCCTGAAGGGCAAGGGCGTCTCCTACATGGAGACCGAACCCGGCTGGCACCTCGGCTATC
TCGACCCCTCGGACGCCGCCCGCGCCGTCGAGGAAATCATGAACCGCACCATCTGA

Upstream 100 bases:

>100_bases
CCGCTAGCCACACTCCTTGATAGATGATATATCATATTTTATTGAATCGGAGCCGATGCCGCCCCCCTCATCCGCGCCGC
TCCCGCGGGGCATGAGGGCG

Downstream 100 bases:

>100_bases
GCCTAGGACACGCCTTTCATGAACCGGCCCCTTTCACCCAATTCCTGGCAATACCGCGAGCTGAACGCCAAGACCCCCGG
CCTCAGCCACCTCTCCGACG

Product: transketolase domain-containing protein

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSCRSRGPPRQRAFMSAAERTLPHDARHASNFRPTAETLALLREKARFVRLETIRLIEVAKVGHYSSVFSAAEIFAALYY
DVMDITHGDPRRPDRDRFLMGKGHAAVGLFPILAELGYIDRETLDNYTRLGNPLGDHPDMRKVPGIDFSSGSIGHALSAG
LGMALGGRMQDRAFNVFVMLGDGEMQEGQVWEAAISAAHHKASNLVAIVDRNGFQLDGAVDDVMGIEPLDEKWRAFGWEV
HTVDGHDLDALTTLLRQVKADEGRTRPCCIIARTLKGKGVSYMETEPGWHLGYLDPSDAARAVEEIMNRTI

Sequences:

>Translated_311_residues
MSCRSRGPPRQRAFMSAAERTLPHDARHASNFRPTAETLALLREKARFVRLETIRLIEVAKVGHYSSVFSAAEIFAALYY
DVMDITHGDPRRPDRDRFLMGKGHAAVGLFPILAELGYIDRETLDNYTRLGNPLGDHPDMRKVPGIDFSSGSIGHALSAG
LGMALGGRMQDRAFNVFVMLGDGEMQEGQVWEAAISAAHHKASNLVAIVDRNGFQLDGAVDDVMGIEPLDEKWRAFGWEV
HTVDGHDLDALTTLLRQVKADEGRTRPCCIIARTLKGKGVSYMETEPGWHLGYLDPSDAARAVEEIMNRTI
>Mature_310_residues
SCRSRGPPRQRAFMSAAERTLPHDARHASNFRPTAETLALLREKARFVRLETIRLIEVAKVGHYSSVFSAAEIFAALYYD
VMDITHGDPRRPDRDRFLMGKGHAAVGLFPILAELGYIDRETLDNYTRLGNPLGDHPDMRKVPGIDFSSGSIGHALSAGL
GMALGGRMQDRAFNVFVMLGDGEMQEGQVWEAAISAAHHKASNLVAIVDRNGFQLDGAVDDVMGIEPLDEKWRAFGWEVH
TVDGHDLDALTTLLRQVKADEGRTRPCCIIARTLKGKGVSYMETEPGWHLGYLDPSDAARAVEEIMNRTI

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=284, Percent_Identity=35.5633802816901, Blast_Score=184, Evalue=8e-47,
Organism=Homo sapiens, GI205277463, Length=281, Percent_Identity=35.5871886120996, Blast_Score=174, Evalue=8e-44,
Organism=Homo sapiens, GI4507521, Length=281, Percent_Identity=35.5871886120996, Blast_Score=174, Evalue=8e-44,
Organism=Homo sapiens, GI225637459, Length=280, Percent_Identity=29.6428571428571, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI225637461, Length=280, Percent_Identity=28.9285714285714, Blast_Score=121, Evalue=6e-28,
Organism=Homo sapiens, GI225637463, Length=237, Percent_Identity=28.6919831223629, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI1788808, Length=249, Percent_Identity=28.1124497991968, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI48994911, Length=249, Percent_Identity=26.5060240963855, Blast_Score=102, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17539652, Length=250, Percent_Identity=36.4, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6325331, Length=246, Percent_Identity=30.0813008130081, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319593, Length=242, Percent_Identity=26.8595041322314, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI45551847, Length=262, Percent_Identity=33.587786259542, Blast_Score=150, Evalue=8e-37,
Organism=Drosophila melanogaster, GI45550715, Length=262, Percent_Identity=33.587786259542, Blast_Score=150, Evalue=8e-37,
Organism=Drosophila melanogaster, GI24666278, Length=265, Percent_Identity=33.5849056603774, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24645119, Length=216, Percent_Identity=33.3333333333333, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 34413; Mature: 34281

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCRSRGPPRQRAFMSAAERTLPHDARHASNFRPTAETLALLREKARFVRLETIRLIEVA
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KVGHYSSVFSAAEIFAALYYDVMDITHGDPRRPDRDRFLMGKGHAAVGLFPILAELGYID
HCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCC
RETLDNYTRLGNPLGDHPDMRKVPGIDFSSGSIGHALSAGLGMALGGRMQDRAFNVFVML
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEE
GDGEMQEGQVWEAAISAAHHKASNLVAIVDRNGFQLDGAVDDVMGIEPLDEKWRAFGWEV
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEECCCHHHHCCCCCHHHHHHHHCCEE
HTVDGHDLDALTTLLRQVKADEGRTRPCCIIARTLKGKGVSYMETEPGWHLGYLDPSDAA
EEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEECCCCEEECCCCHHHHH
RAVEEIMNRTI
HHHHHHHHCCC
>Mature Secondary Structure 
SCRSRGPPRQRAFMSAAERTLPHDARHASNFRPTAETLALLREKARFVRLETIRLIEVA
CCCCCCCHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KVGHYSSVFSAAEIFAALYYDVMDITHGDPRRPDRDRFLMGKGHAAVGLFPILAELGYID
HCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCC
RETLDNYTRLGNPLGDHPDMRKVPGIDFSSGSIGHALSAGLGMALGGRMQDRAFNVFVML
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEE
GDGEMQEGQVWEAAISAAHHKASNLVAIVDRNGFQLDGAVDDVMGIEPLDEKWRAFGWEV
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEECCCHHHHCCCCCHHHHHHHHCCEE
HTVDGHDLDALTTLLRQVKADEGRTRPCCIIARTLKGKGVSYMETEPGWHLGYLDPSDAA
EEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEECCCCEEECCCCHHHHH
RAVEEIMNRTI
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]