Click here to switch to the map view.

The map label for this gene is yqeF [C]

Identifier: 154245950

GI number: 154245950

Start: 2262963

End: 2264093

Strand: Direct

Name: yqeF [C]

Synonym: Xaut_2007

Alternate gene names: 154245950

Gene position: 2262963-2264093 (Clockwise)

Preceding gene: 154245949

Following gene: 154245951

Centisome position: 42.63

GC content: 74.98

Gene sequence:

>1131_bases
ATGACCGGCGTCGCCCTTCTGGCCGCCAGGCGCACGGCGGTGGTGCCGCGCGGCGGCGCCTTCCGCGACATGGAGCCCTT
CGCCCTGGCGGCGGCCCTGATCGGACCCATCCTCGCCGAGGCCGGCATAGCTGCGGCCGCAGTGGACGAGGTGATTCTCG
GCAATGCCCTGTCCGGCGGGGGCAATGTGGCGCGGGTGGCGGCGCTCGCCGCCGGCCTGCCCCAGCACGTCCCGGCGCTG
ACGCTGGACACCCAATGCTGTTCGGGCCTCGACGCCATCCGCATGGGCGCGGCCCGCATTGCTGCGGGGGAGGCGCGCTA
TGTGCTCGCCGGGGGCGTGGAAAGCTTCAGCCGCGCCCCGCTGCGCGCCCATCGTCCGCGCAACAAGGACGAGGCGCCGG
CCTTCTACCGCCAGCCCGCTTTCACCCCCTGGCCGGAGCGCGAGCCGGACCTTGCCGCCGCAGCGGCGGAACTGGCCCGC
GCCGAGGGCATCCCCCGGCCGGCACAGGAGGCCTTTGCGATGGAAAGCCATCGCCGTGCGCTGGCTCTCCCGCCGCCGGA
CGGCGAGATCGTGCCGGTGATTGGCGTGGCCACGGACCCGTTCGCGCGGGTCCTGTCCCCGGCCTTGCTGGCCCGCCTGC
CGGTGATCGCGGGGGACGCGGCCTTCGGGGTCACCGCCGCCACCACGGCGGTGGAGGCGGATGCGGCGGCCATGGTGCTG
CTCGGGCCGGGTGGGGCAGGGCCTGTTCAAGTGCTGGGCGCCCTGGCGCGGGGCGGAGATCCGTTGATGCCGGCGCTGGC
GCCGGTGCCGGCGGTGGAGGCCCTGTGCGGGCGGCTCGGCCTTCATGCGCGCGACATGGAACATGTGGAACTGATGGAGG
CCTATGCCGCCCAGGCCCTCGCCGGCATCGGGCGCCTTGGCCTTGATCCGGCGCGGGTGAATGCGCAGGGCGGCGCGCTC
GCCCGGGGCCATCCCATCGGGGCTTCGGGGGCGGTGCTGGCGGTTCGGGCCTTCCAACGGCTGCGGGCTGCGGGCGGCCG
GGCGCTGGTGGCCATCGCCGGGGCGGGCGGCATCGCCAGCGCCATGGTGCTATCCGGGAAAGACGAAACCCTCCCGCCGT
GGCAGGATTGA

Upstream 100 bases:

>100_bases
GGCTTTATGCGCGGGTCGCCCGCTGGCCGCTGACGGCCTCCGGCAAGACCGATTTTGCCGCCGTCGCCCGCCTGTGGCCG
CACGATTGCGAGCTGATCCC

Downstream 100 bases:

>100_bases
AAGATGAGATCTGGACAGGATTCCGGCGGCGGCAAGATCGCGCGACCGGACACCGCTGGCCCTGCCGGGCCGCCGGCCGC
CGTTTCGGCCGCGGGGCAGG

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MTGVALLAARRTAVVPRGGAFRDMEPFALAAALIGPILAEAGIAAAAVDEVILGNALSGGGNVARVAALAAGLPQHVPAL
TLDTQCCSGLDAIRMGAARIAAGEARYVLAGGVESFSRAPLRAHRPRNKDEAPAFYRQPAFTPWPEREPDLAAAAAELAR
AEGIPRPAQEAFAMESHRRALALPPPDGEIVPVIGVATDPFARVLSPALLARLPVIAGDAAFGVTAATTAVEADAAAMVL
LGPGGAGPVQVLGALARGGDPLMPALAPVPAVEALCGRLGLHARDMEHVELMEAYAAQALAGIGRLGLDPARVNAQGGAL
ARGHPIGASGAVLAVRAFQRLRAAGGRALVAIAGAGGIASAMVLSGKDETLPPWQD

Sequences:

>Translated_376_residues
MTGVALLAARRTAVVPRGGAFRDMEPFALAAALIGPILAEAGIAAAAVDEVILGNALSGGGNVARVAALAAGLPQHVPAL
TLDTQCCSGLDAIRMGAARIAAGEARYVLAGGVESFSRAPLRAHRPRNKDEAPAFYRQPAFTPWPEREPDLAAAAAELAR
AEGIPRPAQEAFAMESHRRALALPPPDGEIVPVIGVATDPFARVLSPALLARLPVIAGDAAFGVTAATTAVEADAAAMVL
LGPGGAGPVQVLGALARGGDPLMPALAPVPAVEALCGRLGLHARDMEHVELMEAYAAQALAGIGRLGLDPARVNAQGGAL
ARGHPIGASGAVLAVRAFQRLRAAGGRALVAIAGAGGIASAMVLSGKDETLPPWQD
>Mature_375_residues
TGVALLAARRTAVVPRGGAFRDMEPFALAAALIGPILAEAGIAAAAVDEVILGNALSGGGNVARVAALAAGLPQHVPALT
LDTQCCSGLDAIRMGAARIAAGEARYVLAGGVESFSRAPLRAHRPRNKDEAPAFYRQPAFTPWPEREPDLAAAAAELARA
EGIPRPAQEAFAMESHRRALALPPPDGEIVPVIGVATDPFARVLSPALLARLPVIAGDAAFGVTAATTAVEADAAAMVLL
GPGGAGPVQVLGALARGGDPLMPALAPVPAVEALCGRLGLHARDMEHVELMEAYAAQALAGIGRLGLDPARVNAQGGALA
RGHPIGASGAVLAVRAFQRLRAAGGRALVAIAGAGGIASAMVLSGKDETLPPWQD

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI167614485, Length=384, Percent_Identity=30.9895833333333, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI148539872, Length=392, Percent_Identity=31.1224489795918, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI4557237, Length=386, Percent_Identity=29.7927461139896, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4504327, Length=420, Percent_Identity=28.5714285714286, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI4501853, Length=396, Percent_Identity=28.2828282828283, Blast_Score=105, Evalue=6e-23,
Organism=Escherichia coli, GI87082165, Length=389, Percent_Identity=33.9331619537275, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1787663, Length=404, Percent_Identity=35.8910891089109, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI48994986, Length=394, Percent_Identity=33.756345177665, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788554, Length=393, Percent_Identity=33.587786259542, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788683, Length=407, Percent_Identity=26.5356265356265, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17535921, Length=385, Percent_Identity=29.6103896103896, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI25147385, Length=361, Percent_Identity=30.4709141274238, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI133906874, Length=388, Percent_Identity=29.639175257732, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17551802, Length=422, Percent_Identity=27.4881516587678, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17535917, Length=350, Percent_Identity=27.7142857142857, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325229, Length=353, Percent_Identity=32.5779036827195, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6322031, Length=371, Percent_Identity=29.9191374663073, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24655093, Length=389, Percent_Identity=34.7043701799486, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24640423, Length=387, Percent_Identity=31.5245478036176, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI17648125, Length=388, Percent_Identity=30.1546391752577, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17137578, Length=427, Percent_Identity=28.1030444964871, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 37833; Mature: 37702

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00737 THIOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGVALLAARRTAVVPRGGAFRDMEPFALAAALIGPILAEAGIAAAAVDEVILGNALSGG
CCCHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCC
GNVARVAALAAGLPQHVPALTLDTQCCSGLDAIRMGAARIAAGEARYVLAGGVESFSRAP
CCHHHHHHHHHCCHHHCCEEEECHHHHCCHHHHHHHHHHHCCCCCEEEEECCHHHHHCCC
LRAHRPRNKDEAPAFYRQPAFTPWPEREPDLAAAAAELARAEGIPRPAQEAFAMESHRRA
CHHCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCE
LALPPPDGEIVPVIGVATDPFARVLSPALLARLPVIAGDAAFGVTAATTAVEADAAAMVL
EECCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEECCCHHCHHHHHHHEECCCEEEEE
LGPGGAGPVQVLGALARGGDPLMPALAPVPAVEALCGRLGLHARDMEHVELMEAYAAQAL
ECCCCCCHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
AGIGRLGLDPARVNAQGGALARGHPIGASGAVLAVRAFQRLRAAGGRALVAIAGAGGIAS
HHHHHCCCCHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
AMVLSGKDETLPPWQD
HHEECCCCCCCCCCCC
>Mature Secondary Structure 
TGVALLAARRTAVVPRGGAFRDMEPFALAAALIGPILAEAGIAAAAVDEVILGNALSGG
CCHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCC
GNVARVAALAAGLPQHVPALTLDTQCCSGLDAIRMGAARIAAGEARYVLAGGVESFSRAP
CCHHHHHHHHHCCHHHCCEEEECHHHHCCHHHHHHHHHHHCCCCCEEEEECCHHHHHCCC
LRAHRPRNKDEAPAFYRQPAFTPWPEREPDLAAAAAELARAEGIPRPAQEAFAMESHRRA
CHHCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCE
LALPPPDGEIVPVIGVATDPFARVLSPALLARLPVIAGDAAFGVTAATTAVEADAAAMVL
EECCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEECCCHHCHHHHHHHEECCCEEEEE
LGPGGAGPVQVLGALARGGDPLMPALAPVPAVEALCGRLGLHARDMEHVELMEAYAAQAL
ECCCCCCHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
AGIGRLGLDPARVNAQGGALARGHPIGASGAVLAVRAFQRLRAAGGRALVAIAGAGGIAS
HHHHHCCCCHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
AMVLSGKDETLPPWQD
HHEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA