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The map label for this gene is pntB [H]

Identifier: 154245893

GI number: 154245893

Start: 2205076

End: 2206482

Strand: Direct

Name: pntB [H]

Synonym: Xaut_1950

Alternate gene names: 154245893

Gene position: 2205076-2206482 (Clockwise)

Preceding gene: 154245892

Following gene: 154245894

Centisome position: 41.54

GC content: 67.24

Gene sequence:

>1407_bases
ATGAACGCGAATTTCGCTGCCCTGCTCTACCTCGTTGCAGGCATCCTCTTCGTCCTCGCCCTGCGCGGCCTTTCCCATCC
CACCACCTCGCGGCAGGGCAACCTGTACGGCATGGTGGGCATGGCCATCGCCGTCCTCACCACGCTGGCGCTCTCGCCGC
CGTCGGACCTCGTCGGCTGGGTGCTGGTGCTGGCCGGCATCGGCATCGGCGGCGGTGTCGGCGCGGTGGTGGCCAAGCGC
ATCGCCATGACCCAGATGCCCCAGCTGGTCGCCGCCTTCCACTCGCTGGTGGGCATGGCTGCGGTGCTGGTGGCGGCCGC
CGCCCTCTACGCGCCGCGTGCTTTCGGCATCGGCGATCCCGGCCACCTCCACGGCGCCAGCCTGGTGGAAATGTCGCTGG
GCGTGGCCATCGGCGCCATCACCTTCACCGGCTCCATCATCGCCTTCGCCAAGCTCAACGGCAACATGAGCGGCAAGCCG
ATCATGCTGCCGTCGCGCCACCTCATCAATGCCGGCCTCGGCATCCTGCTGCTGGTCCTGATCATCGCCTTCGTGATCAC
CGGCTCGATCAAGCTGTTCTGGATCATCACCGTGGTCTCGCTCATCCTCGGCGGGCTGCTCATCATCCCCATCGGCGGCG
CGGACATGCCCGTCGTGGTGTCGATGCTGAACTCCTACTCGGGCTGGGCGGCGGCGGGCATCGGCTTCACCCTGGGCAAC
ACCGCGCTGATCATCACCGGCGCGCTGGTGGGCTCCTCGGGCGCCATCCTGTCCTACATCATGTGCAAGGGCATGAACCG
CTCCTTCATCTCCGTCATCCTCGGCGGCTTCGGCGGTGACGCCGCGGCGGCCGGCGGCGGGGCCCAGGCGGAAGCCCGCC
CGGTGAAGCAGGGCTCGGCGGACGACGCGGCCTACATCATGAAGAACGCCGAGAAGGTCATCATCGTGCCGGGCTACGGC
ATGGCGGTGGCTCAGGCCCAGCACGCCCTGCGCGAGATGGCCGACCTGCTGAAGGAGGAGGGCGTCGAGGTGAAGTACGC
CATCCATCCGGTGGCGGGCCGCATGCCGGGCCACATGAACGTGCTGCTGGCCGAGGCCCAGGTGCCCTACGACGAGGTGT
TCGAGCTGGAGGACATCAACTCCGAGTTCGCCCAGGCGGACGTGGCCTTCGTCATCGGCGCCAACGACGTGACCAACCCG
GCGGCCAAGACCGATCCGCAGTCGCCCATCTTCGGCATGCCGATCCTGGACGTCGAGAAGGCGAAGACCGTGCTCTTCAT
CAAGCGCGGCATGGCGGCGGGCTATGCCGGCGTGGAGAACGAGCTGTTCTTCAAGGACAACACCATGATGCTCTTCGGCG
ACGCCAAGAAGGTCACCGAAGAGGTGGTCAAGGCCTTCGGCCACTGA

Upstream 100 bases:

>100_bases
TTCGTCGCGCTCATCTTCGCCTCGGTGAACATATTCGGCGGGTTCCTCGTGACCAGCCGAATGCTCGCCATGTACTCCAA
GAAGAAGTGAGGCGGAGCAC

Downstream 100 bases:

>100_bases
CCTGAGGCGCTGCGGAACGCAGATCTTCAAAGAGCCGCGCGGCGTCAGCCGGGCGGCTCTTGTCATTTGCACACATGTGG
TGCCTTCCCCAGCTTGACTG

Product: NAD(P)(+) transhydrogenase

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MNANFAALLYLVAGILFVLALRGLSHPTTSRQGNLYGMVGMAIAVLTTLALSPPSDLVGWVLVLAGIGIGGGVGAVVAKR
IAMTQMPQLVAAFHSLVGMAAVLVAAAALYAPRAFGIGDPGHLHGASLVEMSLGVAIGAITFTGSIIAFAKLNGNMSGKP
IMLPSRHLINAGLGILLLVLIIAFVITGSIKLFWIITVVSLILGGLLIIPIGGADMPVVVSMLNSYSGWAAAGIGFTLGN
TALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGDAAAAGGGAQAEARPVKQGSADDAAYIMKNAEKVIIVPGYG
MAVAQAQHALREMADLLKEEGVEVKYAIHPVAGRMPGHMNVLLAEAQVPYDEVFELEDINSEFAQADVAFVIGANDVTNP
AAKTDPQSPIFGMPILDVEKAKTVLFIKRGMAAGYAGVENELFFKDNTMMLFGDAKKVTEEVVKAFGH

Sequences:

>Translated_468_residues
MNANFAALLYLVAGILFVLALRGLSHPTTSRQGNLYGMVGMAIAVLTTLALSPPSDLVGWVLVLAGIGIGGGVGAVVAKR
IAMTQMPQLVAAFHSLVGMAAVLVAAAALYAPRAFGIGDPGHLHGASLVEMSLGVAIGAITFTGSIIAFAKLNGNMSGKP
IMLPSRHLINAGLGILLLVLIIAFVITGSIKLFWIITVVSLILGGLLIIPIGGADMPVVVSMLNSYSGWAAAGIGFTLGN
TALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGDAAAAGGGAQAEARPVKQGSADDAAYIMKNAEKVIIVPGYG
MAVAQAQHALREMADLLKEEGVEVKYAIHPVAGRMPGHMNVLLAEAQVPYDEVFELEDINSEFAQADVAFVIGANDVTNP
AAKTDPQSPIFGMPILDVEKAKTVLFIKRGMAAGYAGVENELFFKDNTMMLFGDAKKVTEEVVKAFGH
>Mature_468_residues
MNANFAALLYLVAGILFVLALRGLSHPTTSRQGNLYGMVGMAIAVLTTLALSPPSDLVGWVLVLAGIGIGGGVGAVVAKR
IAMTQMPQLVAAFHSLVGMAAVLVAAAALYAPRAFGIGDPGHLHGASLVEMSLGVAIGAITFTGSIIAFAKLNGNMSGKP
IMLPSRHLINAGLGILLLVLIIAFVITGSIKLFWIITVVSLILGGLLIIPIGGADMPVVVSMLNSYSGWAAAGIGFTLGN
TALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGDAAAAGGGAQAEARPVKQGSADDAAYIMKNAEKVIIVPGYG
MAVAQAQHALREMADLLKEEGVEVKYAIHPVAGRMPGHMNVLLAEAQVPYDEVFELEDINSEFAQADVAFVIGANDVTNP
AAKTDPQSPIFGMPILDVEKAKTVLFIKRGMAAGYAGVENELFFKDNTMMLFGDAKKVTEEVVKAFGH

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=464, Percent_Identity=46.1206896551724, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI122939153, Length=464, Percent_Identity=46.1206896551724, Blast_Score=380, Evalue=1e-105,
Organism=Escherichia coli, GI1787886, Length=462, Percent_Identity=54.5454545454545, Blast_Score=478, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI17550456, Length=460, Percent_Identity=45.4347826086956, Blast_Score=362, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 48359; Mature: 48359

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNANFAALLYLVAGILFVLALRGLSHPTTSRQGNLYGMVGMAIAVLTTLALSPPSDLVGW
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
VLVLAGIGIGGGVGAVVAKRIAMTQMPQLVAAFHSLVGMAAVLVAAAALYAPRAFGIGDP
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GHLHGASLVEMSLGVAIGAITFTGSIIAFAKLNGNMSGKPIMLPSRHLINAGLGILLLVL
CCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEECCCHHHHHCCHHHHHHHH
IIAFVITGSIKLFWIITVVSLILGGLLIIPIGGADMPVVVSMLNSYSGWAAAGIGFTLGN
HHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCCCHHCCCEECCC
TALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGDAAAAGGGAQAEARPVKQGSA
CEEEEEEEHHCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
DDAAYIMKNAEKVIIVPGYGMAVAQAQHALREMADLLKEEGVEVKYAIHPVAGRMPGHMN
CCHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCE
VLLAEAQVPYDEVFELEDINSEFAQADVAFVIGANDVTNPAAKTDPQSPIFGMPILDVEK
EEEEECCCCHHHHHHHHHCCHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHH
AKTVLFIKRGMAAGYAGVENELFFKDNTMMLFGDAKKVTEEVVKAFGH
HHEEEEEECCCCCCCCCCCCCEEEECCEEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNANFAALLYLVAGILFVLALRGLSHPTTSRQGNLYGMVGMAIAVLTTLALSPPSDLVGW
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
VLVLAGIGIGGGVGAVVAKRIAMTQMPQLVAAFHSLVGMAAVLVAAAALYAPRAFGIGDP
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GHLHGASLVEMSLGVAIGAITFTGSIIAFAKLNGNMSGKPIMLPSRHLINAGLGILLLVL
CCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEECCCHHHHHCCHHHHHHHH
IIAFVITGSIKLFWIITVVSLILGGLLIIPIGGADMPVVVSMLNSYSGWAAAGIGFTLGN
HHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCCCHHCCCEECCC
TALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGDAAAAGGGAQAEARPVKQGSA
CEEEEEEEHHCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
DDAAYIMKNAEKVIIVPGYGMAVAQAQHALREMADLLKEEGVEVKYAIHPVAGRMPGHMN
CCHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCE
VLLAEAQVPYDEVFELEDINSEFAQADVAFVIGANDVTNPAAKTDPQSPIFGMPILDVEK
EEEEECCCCHHHHHHHHHCCHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHH
AKTVLFIKRGMAAGYAGVENELFFKDNTMMLFGDAKKVTEEVVKAFGH
HHEEEEEECCCCCCCCCCCCCEEEECCEEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]