Click here to switch to the map view.

The map label for this gene is zur [H]

Identifier: 154245832

GI number: 154245832

Start: 2127425

End: 2127952

Strand: Direct

Name: zur [H]

Synonym: Xaut_1888

Alternate gene names: 154245832

Gene position: 2127425-2127952 (Clockwise)

Preceding gene: 154245829

Following gene: 154245833

Centisome position: 40.07

GC content: 72.16

Gene sequence:

>528_bases
GTGACCCATTCTGGCGACCATCCTAGTGATCATGATCACGGCCAATGCGTGGCCGGCGCCCTGGCGCGCATGGAGAAGTG
CTGCGCGGAGAAAGGCCTGCGCCTGACGCCGCTGCGCCGTAGCGTCATGAAGGCGCTGGCCGAGACCCACGTGCCGCTCG
GCGCCTACGAGATCGTGGAGCGCCTGGCCGCCGGCGGCGAGCCGACGCCGCCCATGTCGGTCTACCGGGTGCTGGATTTC
CTGGTGGCCGAGGGGCTCGCCCACCGCATCGAGAGCCGCAACGCGTTCCTGGCCTGCGGCCATCCCCATGATGCCGAAGA
GGTGGTGGTGTTCCTCATCTGCGAACGCTGCGGCCTGACCAAGGAAGTGGCCTCCCACGCGGTCGGGCGCGACCTTGCCT
GGGCGGCGCGGGCCGCCGGCTTCGAGCCGCGCCAGCGGGTGCTGGAGGTGGCTGGCACCTGCGCCAGCTGCCGGGAAGCG
GCGTCCGCAGCCGCGCCGGGAGCGGCCGAGACGGCCGGCGCCGGTTGA

Upstream 100 bases:

>100_bases
GCAGATTGCAACGCTCCTCCCCGTGGCGCAACGCGACGTTGGATTGGATGTTGCATACCCGCGGATGGCAGGACGTGCGG
CGATGTACTAAATAGGAAGC

Downstream 100 bases:

>100_bases
CGCTCGCCGCCGCCCGGCCTACTCGAAACCCGTCCGTGCCCCCTCCCGCGCCGTATCAGGGCCGGACGTGCCGGTCGCGG
ACGTGTCTGCGTGCGGACGA

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MTHSGDHPSDHDHGQCVAGALARMEKCCAEKGLRLTPLRRSVMKALAETHVPLGAYEIVERLAAGGEPTPPMSVYRVLDF
LVAEGLAHRIESRNAFLACGHPHDAEEVVVFLICERCGLTKEVASHAVGRDLAWAARAAGFEPRQRVLEVAGTCASCREA
ASAAAPGAAETAGAG

Sequences:

>Translated_175_residues
MTHSGDHPSDHDHGQCVAGALARMEKCCAEKGLRLTPLRRSVMKALAETHVPLGAYEIVERLAAGGEPTPPMSVYRVLDF
LVAEGLAHRIESRNAFLACGHPHDAEEVVVFLICERCGLTKEVASHAVGRDLAWAARAAGFEPRQRVLEVAGTCASCREA
ASAAAPGAAETAGAG
>Mature_174_residues
THSGDHPSDHDHGQCVAGALARMEKCCAEKGLRLTPLRRSVMKALAETHVPLGAYEIVERLAAGGEPTPPMSVYRVLDFL
VAEGLAHRIESRNAFLACGHPHDAEEVVVFLICERCGLTKEVASHAVGRDLAWAARAAGFEPRQRVLEVAGTCASCREAA
SAAAPGAAETAGAG

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=146, Percent_Identity=33.5616438356164, Blast_Score=94, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18420; Mature: 18289

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHSGDHPSDHDHGQCVAGALARMEKCCAEKGLRLTPLRRSVMKALAETHVPLGAYEIVE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
RLAAGGEPTPPMSVYRVLDFLVAEGLAHRIESRNAFLACGHPHDAEEVVVFLICERCGLT
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCH
KEVASHAVGRDLAWAARAAGFEPRQRVLEVAGTCASCREAASAAAPGAAETAGAG
HHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
THSGDHPSDHDHGQCVAGALARMEKCCAEKGLRLTPLRRSVMKALAETHVPLGAYEIVE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
RLAAGGEPTPPMSVYRVLDFLVAEGLAHRIESRNAFLACGHPHDAEEVVVFLICERCGLT
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCH
KEVASHAVGRDLAWAARAAGFEPRQRVLEVAGTCASCREAASAAAPGAAETAGAG
HHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]