Click here to switch to the map view.

The map label for this gene is alsR [H]

Identifier: 154244561

GI number: 154244561

Start: 678728

End: 679645

Strand: Reverse

Name: alsR [H]

Synonym: Xaut_0606

Alternate gene names: 154244561

Gene position: 679645-678728 (Counterclockwise)

Preceding gene: 154244562

Following gene: 154244549

Centisome position: 12.8

GC content: 55.88

Gene sequence:

>918_bases
ATGAATAATAATCCGCCAAAAACCTCCGGGAGCATGAGACATTTACGTCATTTTATCACCGCTGCAGAGGCAGGAAGCCT
TCGGCGCGCTGCGGAGGTGCTGGGTTTGCAGGAATCGACGGTCAGCCGATCGGTGCGAGACCTGGAGGATCAGCTCGGGG
CCTCGTTATTTCTCCGGCACCCCAGTGGTGTGACTCTTACGTTGGCAGGACAATGCTTTCTTCACCGCGCACGTCAGGCA
CTTGTGCAACTTCAGAAAGGCTGGGAAGAGGTCGCGGCAATTGGACGTTCGGAAAACGGGATCTTAAGGATAGGCATTTT
CTCAACCCTGGCTTCTGGTTTTATGGGAGATCTGTTTCGCGCGTATGATGTACATCATTCAAGCGTACATATCGAATTTG
TTGACGCCGAGGCCAATGAACACGCTGCCTCCATTCGGAGCTTTGACATCGACGCGGCATTCGTCATCGGTCGATTCCAG
TGGGCGGAATGCGACTCTCTTCATCTTTGGACCGAGACGGTCTTTATCGCCTTTCCGGAAGGCCATCCATTGACTCGCAA
TGAAGAGGTCACATGGCAGGATCTCGTTGATGAGAGATTTCTTGTGCGGATCGAAGGTTCAGGGGGCGAGGTGCGGGAAT
ATCTCAGAAGGCGCTTAGCTGTTCTCGGGCGTCGCCCGCTCATCAATGCACAACGGATAGGCCGCTCCAGCTTGTTGGGA
CTTGTGGCGTCGGGGCGCGGGGTGGCGCCCGCCACCCAGTCTGAAACCGTGATCTCGGTCCCAGGTGTCGTCTACCGTCC
TATCGCGGGCGAAACTCTACCCTTCTCGGTGCTCTTCTCGCGACGAAACGACAATCCCGCATTTCGGGCGCTGCTCAGTC
TTGCTCGAAGCATGGCTCAGCACTCGGATCGAAGCTGA

Upstream 100 bases:

>100_bases
GAAATAATATAATTAAAGTGATAAAATTATACGCGAATCGCGTGGAAAACAGGGATATGTAAAATTATATTATATAGTAA
TTTTTGTGGATGTCTGATCA

Downstream 100 bases:

>100_bases
CTGAAATGAAAAACACAATGCTTCACCGGGCTGCGCGACGTACTCTCATAAAGCCGCGGTCCGTCACAATGAAGCGCTCC
AGCATGGGCACGATCAGCTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNNNPPKTSGSMRHLRHFITAAEAGSLRRAAEVLGLQESTVSRSVRDLEDQLGASLFLRHPSGVTLTLAGQCFLHRARQA
LVQLQKGWEEVAAIGRSENGILRIGIFSTLASGFMGDLFRAYDVHHSSVHIEFVDAEANEHAASIRSFDIDAAFVIGRFQ
WAECDSLHLWTETVFIAFPEGHPLTRNEEVTWQDLVDERFLVRIEGSGGEVREYLRRRLAVLGRRPLINAQRIGRSSLLG
LVASGRGVAPATQSETVISVPGVVYRPIAGETLPFSVLFSRRNDNPAFRALLSLARSMAQHSDRS

Sequences:

>Translated_305_residues
MNNNPPKTSGSMRHLRHFITAAEAGSLRRAAEVLGLQESTVSRSVRDLEDQLGASLFLRHPSGVTLTLAGQCFLHRARQA
LVQLQKGWEEVAAIGRSENGILRIGIFSTLASGFMGDLFRAYDVHHSSVHIEFVDAEANEHAASIRSFDIDAAFVIGRFQ
WAECDSLHLWTETVFIAFPEGHPLTRNEEVTWQDLVDERFLVRIEGSGGEVREYLRRRLAVLGRRPLINAQRIGRSSLLG
LVASGRGVAPATQSETVISVPGVVYRPIAGETLPFSVLFSRRNDNPAFRALLSLARSMAQHSDRS
>Mature_305_residues
MNNNPPKTSGSMRHLRHFITAAEAGSLRRAAEVLGLQESTVSRSVRDLEDQLGASLFLRHPSGVTLTLAGQCFLHRARQA
LVQLQKGWEEVAAIGRSENGILRIGIFSTLASGFMGDLFRAYDVHHSSVHIEFVDAEANEHAASIRSFDIDAAFVIGRFQ
WAECDSLHLWTETVFIAFPEGHPLTRNEEVTWQDLVDERFLVRIEGSGGEVREYLRRRLAVLGRRPLINAQRIGRSSLLG
LVASGRGVAPATQSETVISVPGVVYRPIAGETLPFSVLFSRRNDNPAFRALLSLARSMAQHSDRS

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788887, Length=287, Percent_Identity=26.1324041811847, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI2367136, Length=289, Percent_Identity=26.2975778546713, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI157672245, Length=190, Percent_Identity=27.3684210526316, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787879, Length=264, Percent_Identity=26.5151515151515, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI145693105, Length=273, Percent_Identity=22.3443223443223, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790399, Length=277, Percent_Identity=24.9097472924188, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081904, Length=200, Percent_Identity=27, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788748, Length=280, Percent_Identity=28.2142857142857, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787601, Length=177, Percent_Identity=25.9887005649718, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1789506, Length=172, Percent_Identity=29.0697674418605, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788481, Length=207, Percent_Identity=28.0193236714976, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786401, Length=120, Percent_Identity=30.8333333333333, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33736; Mature: 33736

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNPPKTSGSMRHLRHFITAAEAGSLRRAAEVLGLQESTVSRSVRDLEDQLGASLFLRH
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEC
PSGVTLTLAGQCFLHRARQALVQLQKGWEEVAAIGRSENGILRIGIFSTLASGFMGDLFR
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHH
AYDVHHSSVHIEFVDAEANEHAASIRSFDIDAAFVIGRFQWAECDSLHLWTETVFIAFPE
HHHCCCCEEEEEEEECCCCHHHHHHHHCCCCEEEEEECEEECCCCCEEEEEEEEEEEECC
GHPLTRNEEVTWQDLVDERFLVRIEGSGGEVREYLRRRLAVLGRRPLINAQRIGRSSLLG
CCCCCCCCCCCHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHH
LVASGRGVAPATQSETVISVPGVVYRPIAGETLPFSVLFSRRNDNPAFRALLSLARSMAQ
HHHCCCCCCCCCCCCEEEECCCEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
HSDRS
HCCCC
>Mature Secondary Structure
MNNNPPKTSGSMRHLRHFITAAEAGSLRRAAEVLGLQESTVSRSVRDLEDQLGASLFLRH
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEC
PSGVTLTLAGQCFLHRARQALVQLQKGWEEVAAIGRSENGILRIGIFSTLASGFMGDLFR
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHH
AYDVHHSSVHIEFVDAEANEHAASIRSFDIDAAFVIGRFQWAECDSLHLWTETVFIAFPE
HHHCCCCEEEEEEEECCCCHHHHHHHHCCCCEEEEEECEEECCCCCEEEEEEEEEEEECC
GHPLTRNEEVTWQDLVDERFLVRIEGSGGEVREYLRRRLAVLGRRPLINAQRIGRSSLLG
CCCCCCCCCCCHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHH
LVASGRGVAPATQSETVISVPGVVYRPIAGETLPFSVLFSRRNDNPAFRALLSLARSMAQ
HHHCCCCCCCCCCCCEEEECCCEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
HSDRS
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]