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The map label for this gene is trkH [H]

Identifier: 154244426

GI number: 154244426

Start: 512845

End: 514341

Strand: Reverse

Name: trkH [H]

Synonym: Xaut_0469

Alternate gene names: 154244426

Gene position: 514341-512845 (Counterclockwise)

Preceding gene: 154244427

Following gene: 154244411

Centisome position: 9.69

GC content: 67.94

Gene sequence:

>1497_bases
ATGCACGCCGCGCGCATCCCAACGGTGGAGGCCGAGGCCGTTTCGGTGCTCAGCCTGCGTCCGGTGGCGGCGACGCTCGG
CGTCCTCCTCGCCATCCTCGGCGTCGCCATGCTGGTGCCGGCGATAGTCGATTTCGCCACGCGCTCCGGCGGACAGGGCG
CCTTCGTCGGCGCCTCTGCCATCACCATCTTCGTCGGCGTGCTGCTGTGGATGAGCGGGCGCAGCCAGAAGGTCAGCAAG
CTCGACCTCCGGCAGGCCTTCCTCCTGACCTCGTCGGTCTGGGTGGTGCTGTCGCTGTTCGCGGCCCTGCCGCTCATGTG
GGGCCATTCCCGCCTCTCCTTTACCGCCGCCATGTTCGAGAGCATGTCCGGGCTCACCACCACCGGAGCCAGCGTGATGT
CGGGGCTGGACGCCATGTCGCCCGGCATCCTGTTGTGGCGGGCGCTGCTGCACTGGTTTGGCGGCATCGGCATCGTGGCC
ATCGCCATAGCGGTGCTGCCCATGCTGTCCATCGGCGGCATGCAGCTGTTCCGCACGGAATCCTCCGACAAGTCGGAGAA
GTTCCTGCCCCGCGCCGGCGCCATCGCCAAGCGCCTGCTCGTCGCCTATGTGCTGCTCACCGCCGTCTGCGCCGGCTTCT
ACCTGATGGCGGGGCTGAAGCCCTTCGATGCCGTCACCATCGCCATGTCCACCCTGTCGAGCGGCGGCTTCGCCAATTCG
GACTCATCGCTCACCGTGTTCGCCAAGCCCGCGGTGGACTATGTGGCCGTAGTCTTCATGCTCATGGCCGCCCTGCCCTT
CCCGCTCTATGTGCGCGCCCTGTCCGGTGACCCGTGGCGGATCTTCTCCAATCCGGAGGTGCGGCTGTTTCTCGCCATCG
TGGCGCTGTTCACCGGCCTCTCCTTCGTGCAGCTCACGGTCAGCGGCGTCGCCTCCGGCGAGACGGCGCTGCGCTGGGCG
CTGTTCACCGTCGCCTCGCTCATTTCCACCACCGGCTTCATGGCGGCGGACTACACCAACTGGGGCACCACCTCCGACGC
CATCTTCTTCGTTCTGATGTTTATCGGCGGCTGCACCGGCTCCACCTCCGGCGGCCTGAAGGCCCTGCGCCTCGCCATCA
CCGCCAAGGCCATCCGCCAGCACCTGAAGCGCATCTCGTTCCGCGCCGGGGTGTTCCCCCTGCGCTACGGCGGCGCGCCG
GTGGCGGACGACGTGGTGGCCTCGGTTCTGTCCTTCGTTTTCCTCTATCTGCTGGCCTTCTTCCTGTTCGGCGTCGCCCT
CAACATGCTGGGCCTCGACCTGAAGACCGCCTTCTCCGCCACCATCGCCTGCCTCGCCAACGTGGGGCCGGGGCTGGGGC
CGCTGGTGGGGCCGGCCTCCAACTACAGCGTCCTGCCGGATTCCGCCCTGTGGCTACTCACGGCGGCCATGCTGCTGGGG
CGGCTGGAGATCCTGACCGTGCTGGTGCTGTTCCTGCCGCGCTTCTGGGTGCGCTGA

Upstream 100 bases:

>100_bases
GACGTTCCCGGAAAATGCTCTATCTCGTTTGCGCATCGCATTTTTTGAACTAACCCGGCATCCACTTCGCTCGAAGACGC
ATTAGGGGAAGGGGGACGTC

Downstream 100 bases:

>100_bases
CGCGCCCTCGCAGCACTGCAGCCGCGCGCTCAAGCCCGCGCGGCGATTGAGCGAAGGCGCCTGGAAGCCCCGCGCGGCGC
TTGAGCGAAAGAACGCGGAA

Product: cation transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MHAARIPTVEAEAVSVLSLRPVAATLGVLLAILGVAMLVPAIVDFATRSGGQGAFVGASAITIFVGVLLWMSGRSQKVSK
LDLRQAFLLTSSVWVVLSLFAALPLMWGHSRLSFTAAMFESMSGLTTTGASVMSGLDAMSPGILLWRALLHWFGGIGIVA
IAIAVLPMLSIGGMQLFRTESSDKSEKFLPRAGAIAKRLLVAYVLLTAVCAGFYLMAGLKPFDAVTIAMSTLSSGGFANS
DSSLTVFAKPAVDYVAVVFMLMAALPFPLYVRALSGDPWRIFSNPEVRLFLAIVALFTGLSFVQLTVSGVASGETALRWA
LFTVASLISTTGFMAADYTNWGTTSDAIFFVLMFIGGCTGSTSGGLKALRLAITAKAIRQHLKRISFRAGVFPLRYGGAP
VADDVVASVLSFVFLYLLAFFLFGVALNMLGLDLKTAFSATIACLANVGPGLGPLVGPASNYSVLPDSALWLLTAAMLLG
RLEILTVLVLFLPRFWVR

Sequences:

>Translated_498_residues
MHAARIPTVEAEAVSVLSLRPVAATLGVLLAILGVAMLVPAIVDFATRSGGQGAFVGASAITIFVGVLLWMSGRSQKVSK
LDLRQAFLLTSSVWVVLSLFAALPLMWGHSRLSFTAAMFESMSGLTTTGASVMSGLDAMSPGILLWRALLHWFGGIGIVA
IAIAVLPMLSIGGMQLFRTESSDKSEKFLPRAGAIAKRLLVAYVLLTAVCAGFYLMAGLKPFDAVTIAMSTLSSGGFANS
DSSLTVFAKPAVDYVAVVFMLMAALPFPLYVRALSGDPWRIFSNPEVRLFLAIVALFTGLSFVQLTVSGVASGETALRWA
LFTVASLISTTGFMAADYTNWGTTSDAIFFVLMFIGGCTGSTSGGLKALRLAITAKAIRQHLKRISFRAGVFPLRYGGAP
VADDVVASVLSFVFLYLLAFFLFGVALNMLGLDLKTAFSATIACLANVGPGLGPLVGPASNYSVLPDSALWLLTAAMLLG
RLEILTVLVLFLPRFWVR
>Mature_498_residues
MHAARIPTVEAEAVSVLSLRPVAATLGVLLAILGVAMLVPAIVDFATRSGGQGAFVGASAITIFVGVLLWMSGRSQKVSK
LDLRQAFLLTSSVWVVLSLFAALPLMWGHSRLSFTAAMFESMSGLTTTGASVMSGLDAMSPGILLWRALLHWFGGIGIVA
IAIAVLPMLSIGGMQLFRTESSDKSEKFLPRAGAIAKRLLVAYVLLTAVCAGFYLMAGLKPFDAVTIAMSTLSSGGFANS
DSSLTVFAKPAVDYVAVVFMLMAALPFPLYVRALSGDPWRIFSNPEVRLFLAIVALFTGLSFVQLTVSGVASGETALRWA
LFTVASLISTTGFMAADYTNWGTTSDAIFFVLMFIGGCTGSTSGGLKALRLAITAKAIRQHLKRISFRAGVFPLRYGGAP
VADDVVASVLSFVFLYLLAFFLFGVALNMLGLDLKTAFSATIACLANVGPGLGPLVGPASNYSVLPDSALWLLTAAMLLG
RLEILTVLVLFLPRFWVR

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=485, Percent_Identity=35.0515463917526, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI1787626, Length=484, Percent_Identity=32.8512396694215, Blast_Score=240, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52654; Mature: 52654

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]