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The map label for this gene is argG [H]

Identifier: 153952360

GI number: 153952360

Start: 1178567

End: 1179787

Strand: Direct

Name: argG [H]

Synonym: JJD26997_1334

Alternate gene names: 153952360

Gene position: 1178567-1179787 (Clockwise)

Preceding gene: 153951560

Following gene: 153951618

Centisome position: 63.88

GC content: 37.43

Gene sequence:

>1221_bases
ATGAAAAATGAAGTAAAAAAAGTAGTTTTAGCGTATTCTGGGGGGCTTGATACGAGTATTATTTTAAAATGGCTTCAAGA
TGAGTATAATTGTGAAGTTGTAACTTTTACAGCAGATATTGGTCAAGGCGAAGAACTCGAGCCTGCAAGAAAAAAAGCCC
TTTCTTTAGGCATAAAAGAAGAAAATATTTTCATTAAAGATTTAAGAGATGAATTTGTTAAAGATTATGTATTTCCTATG
TTTAGAGCCAATGCGATTTATGAAGGAGAGTATCTTTTAGGAACAAGTATAGCAAGACCACTTATAGCAAAAACTCAAGC
ACAAATCGCCCTGCAAACAGGTGCTGATGCGGTAAGTCATGGCGCCACAGGCAAAGGAAACGATCAAGTGCGTTTTGAAC
TTGGTTATCTTGCTTTTAACCCAGATTTAAAAATCATCGCTCCATGGCGTGAGTGGGATTTAAACAGCCGTGAAAAACTC
CTTGCTTATGCGCAAAAACACGGTATTGATATTTCTAAGAAAAAAGGGAAATCTCCTTATTCTATGGACGCAAATTTACT
TCATATTTCTTACGAAGGACTTGTTTTAGAAGATCCTGCACACGCACCTGAAGAAGATATGTGGAGATGGAGTAAAAGTC
CAAAAGACGCTCCACATGAAAGTGAAATTATAGAACTTGATTTCCAAAAAGGAGATTTAGTAGCGATAAATGGAGAAAAA
CTAAGTCCTGCAGGACTTTTAACCAAACTTAACGAACTAGGCTGCAAACACGGTATAGGACGCCTTGATATAGTAGAAAA
TCGCTATGTAGGAATGAAAAGCCGTGGTTGTTACGAAACTCCAGGCGGTACTATACTTTTAAAAGCACACAGAGCCCTTG
AAAGCATCACGCTTGATAGAGAAGCAGCACACTTAAAAGATGAACTCATGCCAAAATACGCGAGTTTAATTTACAATGGC
TATTGGTTCTCGCCTGAAAGAATGATGCTTCAAGCCTTAATCGATGAGTCTCAAATTCACGCCAATGGTAGAGTAAAACT
CGAGCTTTATAAAGGCAATGTAATGGTTATAGGACGCCAAAGTGCAAACGATAGCTTGTTTAATGCAGCTTATTGTACTT
TTGAAGAAGATGAAGTGTATAACCAAAAAGACGCAGCAGGCTTTATCAAGCTTAATGCTTTGCGTTTTATCATCGCAGGA
AAAAATGGAAGAAAATTTTAA

Upstream 100 bases:

>100_bases
TGCTTTATTTTTTAAGAAATATAGAAAGTAAAAACTTTTCTTTAATGAAATTTGGATACAATTTTACAATTTTCAAATCT
ATTTTAACAAAGGATATCTT

Downstream 100 bases:

>100_bases
TAAAGGAATAAAATGAAAGTATTATTAATCAAAGATGTAAAAGCACTTGGAAAAGCAGGAGAAATAAAAGAAGTAAAAGA
CGGCTACGGACAAAATTTCT

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MKNEVKKVVLAYSGGLDTSIILKWLQDEYNCEVVTFTADIGQGEELEPARKKALSLGIKEENIFIKDLRDEFVKDYVFPM
FRANAIYEGEYLLGTSIARPLIAKTQAQIALQTGADAVSHGATGKGNDQVRFELGYLAFNPDLKIIAPWREWDLNSREKL
LAYAQKHGIDISKKKGKSPYSMDANLLHISYEGLVLEDPAHAPEEDMWRWSKSPKDAPHESEIIELDFQKGDLVAINGEK
LSPAGLLTKLNELGCKHGIGRLDIVENRYVGMKSRGCYETPGGTILLKAHRALESITLDREAAHLKDELMPKYASLIYNG
YWFSPERMMLQALIDESQIHANGRVKLELYKGNVMVIGRQSANDSLFNAAYCTFEEDEVYNQKDAAGFIKLNALRFIIAG
KNGRKF

Sequences:

>Translated_406_residues
MKNEVKKVVLAYSGGLDTSIILKWLQDEYNCEVVTFTADIGQGEELEPARKKALSLGIKEENIFIKDLRDEFVKDYVFPM
FRANAIYEGEYLLGTSIARPLIAKTQAQIALQTGADAVSHGATGKGNDQVRFELGYLAFNPDLKIIAPWREWDLNSREKL
LAYAQKHGIDISKKKGKSPYSMDANLLHISYEGLVLEDPAHAPEEDMWRWSKSPKDAPHESEIIELDFQKGDLVAINGEK
LSPAGLLTKLNELGCKHGIGRLDIVENRYVGMKSRGCYETPGGTILLKAHRALESITLDREAAHLKDELMPKYASLIYNG
YWFSPERMMLQALIDESQIHANGRVKLELYKGNVMVIGRQSANDSLFNAAYCTFEEDEVYNQKDAAGFIKLNALRFIIAG
KNGRKF
>Mature_406_residues
MKNEVKKVVLAYSGGLDTSIILKWLQDEYNCEVVTFTADIGQGEELEPARKKALSLGIKEENIFIKDLRDEFVKDYVFPM
FRANAIYEGEYLLGTSIARPLIAKTQAQIALQTGADAVSHGATGKGNDQVRFELGYLAFNPDLKIIAPWREWDLNSREKL
LAYAQKHGIDISKKKGKSPYSMDANLLHISYEGLVLEDPAHAPEEDMWRWSKSPKDAPHESEIIELDFQKGDLVAINGEK
LSPAGLLTKLNELGCKHGIGRLDIVENRYVGMKSRGCYETPGGTILLKAHRALESITLDREAAHLKDELMPKYASLIYNG
YWFSPERMMLQALIDESQIHANGRVKLELYKGNVMVIGRQSANDSLFNAAYCTFEEDEVYNQKDAAGFIKLNALRFIIAG
KNGRKF

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=398, Percent_Identity=46.2311557788945, Blast_Score=340, Evalue=1e-93,
Organism=Homo sapiens, GI16950633, Length=398, Percent_Identity=46.2311557788945, Blast_Score=340, Evalue=1e-93,
Organism=Escherichia coli, GI1789563, Length=414, Percent_Identity=28.2608695652174, Blast_Score=124, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324514, Length=404, Percent_Identity=44.3069306930693, Blast_Score=345, Evalue=8e-96,
Organism=Drosophila melanogaster, GI21358151, Length=403, Percent_Identity=44.9131513647643, Blast_Score=339, Evalue=2e-93,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 45628; Mature: 45628

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNEVKKVVLAYSGGLDTSIILKWLQDEYNCEVVTFTADIGQGEELEPARKKALSLGIKE
CCCHHEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCC
ENIFIKDLRDEFVKDYVFPMFRANAIYEGEYLLGTSIARPLIAKTQAQIALQTGADAVSH
CCEEHHHHHHHHHHHHHHHHHHCCEEECCCEEECHHHHHHHHHHHHHEEEEECCCHHHHC
GATGKGNDQVRFELGYLAFNPDLKIIAPWREWDLNSREKLLAYAQKHGIDISKKKGKSPY
CCCCCCCCEEEEEEEEEEECCCEEEEECHHHCCCCCHHHHHHHHHHHCCCCHHHCCCCCC
SMDANLLHISYEGLVLEDPAHAPEEDMWRWSKSPKDAPHESEIIELDFQKGDLVAINGEK
CCCCEEEEEEECCEEEECCCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEECCCC
LSPAGLLTKLNELGCKHGIGRLDIVENRYVGMKSRGCYETPGGTILLKAHRALESITLDR
CCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEECCCCEEEEEEHHHHHHHHCCH
EAAHLKDELMPKYASLIYNGYWFSPERMMLQALIDESQIHANGRVKLELYKGNVMVIGRQ
HHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHCHHHCCCCCEEEEEEEECCEEEEECC
SANDSLFNAAYCTFEEDEVYNQKDAAGFIKLNALRFIIAGKNGRKF
CCCCCEEEEEEEEECHHHHCCCCCCCCEEEEEEEEEEEECCCCCCC
>Mature Secondary Structure
MKNEVKKVVLAYSGGLDTSIILKWLQDEYNCEVVTFTADIGQGEELEPARKKALSLGIKE
CCCHHEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCC
ENIFIKDLRDEFVKDYVFPMFRANAIYEGEYLLGTSIARPLIAKTQAQIALQTGADAVSH
CCEEHHHHHHHHHHHHHHHHHHCCEEECCCEEECHHHHHHHHHHHHHEEEEECCCHHHHC
GATGKGNDQVRFELGYLAFNPDLKIIAPWREWDLNSREKLLAYAQKHGIDISKKKGKSPY
CCCCCCCCEEEEEEEEEEECCCEEEEECHHHCCCCCHHHHHHHHHHHCCCCHHHCCCCCC
SMDANLLHISYEGLVLEDPAHAPEEDMWRWSKSPKDAPHESEIIELDFQKGDLVAINGEK
CCCCEEEEEEECCEEEECCCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEECCCC
LSPAGLLTKLNELGCKHGIGRLDIVENRYVGMKSRGCYETPGGTILLKAHRALESITLDR
CCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEECCCCEEEEEEHHHHHHHHCCH
EAAHLKDELMPKYASLIYNGYWFSPERMMLQALIDESQIHANGRVKLELYKGNVMVIGRQ
HHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHCHHHCCCCCEEEEEEEECCEEEEECC
SANDSLFNAAYCTFEEDEVYNQKDAAGFIKLNALRFIIAGKNGRKF
CCCCCEEEEEEEEECHHHHCCCCCCCCEEEEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA