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The map label for this gene is yfmM [H]

Identifier: 153937826

GI number: 153937826

Start: 1896661

End: 1898217

Strand: Reverse

Name: yfmM [H]

Synonym: CLC_1789

Alternate gene names: 153937826

Gene position: 1898217-1896661 (Counterclockwise)

Preceding gene: 153935257

Following gene: 153936305

Centisome position: 50.48

GC content: 32.05

Gene sequence:

>1557_bases
ATGAGTATATTAACCGTTAAGGATATTAGCCATGGATTTGGAGACAGAGCTATTTTTGAGGAAGTATCCTTTAGACTTTT
AAAGGGAGAGCATGTAGGACTTATTGGAGCTAATGGAGAGGGTAAGTCTACATTTATGAATATAATAACAGGAAAACTAA
TGCCAGATGAGGGGAAAATTCAATGGGCAAAGGATGTAAGAGTAGGCTACATGGATCAGCATTTAAATCTTACAAAGGGA
AAAACCATTAGAGAAGTTTTGAGGGAAGCCTTTGACTATTTATTTAATCTTGAAAAAGAAATGAATGATTTATACACGAA
AATGGGAGAGGTATCCCAGGAAGAAATGGAAAAAATGCTAAATAGAACAGCTACTATACAGGATATGTTAGATCATAATG
ATTTTTACATAATAGATGCTAAAATAGAGGAAATAGCAAGGGGACTTGGTATTGCTGACATAGGTTTGGATAAGGATGTA
TCAGATTTATCTGGAGGACAAAGAACAAAAATACTTCTAGCAAAACTCCTTTTAGAAAATCCAGATATATTACTTTTAGA
TGAGCCTACAAACTATTTAGACGAAGATCACATAGATTGGCTTAAAAATTATCTTAAAAACTACGAAAATGCCTTTATAT
TAATATCCCATGATATACCATTTTTAAATGAGGTAATAAATTTAATTTATCATGTAGAAAATAAAAGACTTACTCGGTAC
GTAGGGGATTATAATGAATTTAGAAGAGTTTATGAGGAAAATAAGAAACGACTAGAGGCGGCCTATGAAAGGCAACAGGC
AGAAATATCAAAACTAGAAGATTTTATAGCCAAAAATAAAGCAAGAGTTTCCACCGTAGGTATGGCAAGATCTAGACAAA
AAAAATTAGATAAAATAGATAAAATAGAACTTACAAAAGAAAAACCAAAGCCAGAATTTAATTTTAAACAGGCTAGAGCT
TCTGGAAAAGTTATATTTGAAACTAAAGATTTAGTTATAGGCTATGATTCACCTTTAACAAAACCTTTAAATATAAAAAT
GGAAAGAGGACAAAAGGTAGCCTTAGTAGGAGCCAATGGTCTTGGAAAAACTACATTACTAAAAAGTTTATTAGGAGCTA
TAAAACCATTGGAAGGGGATGTTACGCTAGGTGATTATCAATACATAGGATATTTTGAGCAAGAAGAAAGAGAATCTAAT
TATAATACCTGTATAGAAGAAGTGTGGAAAGAGTTCCCTGTATTTACTCAATACGAAATAAGATCTGCCCTAGCAAAATG
TGGATTAACTACGAAGCAATTAGAATCTAAAATAGTAGTGCTGTCCGGTGGAGAAGCAGCAAAGGTAAGGCTTTGTAAAA
TACTAAATAGAGAAACCAATATACTAATATTAGACGAACCTACTAACCACTTAGATGTGGAAGCCAAAGAAGAATTAAAA
AGAGCATTAAGAGAATATAAAGGTTCTATACTTTTAGTTTGCCACGAAAAAGAATTTTATGAAGATATAGTAACAGAAAC
TTGGAATTGTGAAAGTTGGACTACAAAGATTGTGTAA

Upstream 100 bases:

>100_bases
TAAAAAGAAACTAAATTTATATTTTAAATAAATTATTGACAAGGCTTTATTTATAAATTAAAGTTTATTTTAGATTATAT
TTTCAGGAGGACTTTTACAT

Downstream 100 bases:

>100_bases
TATTATAATTGTTTTCACATAAATTATTGTAAATTAATTATATAAATTTGTAATAAAGTACATATTAATGTATAATTTAA
TTATATTAACAATAATTTTA

Product: drug resistance ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MSILTVKDISHGFGDRAIFEEVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLMPDEGKIQWAKDVRVGYMDQHLNLTKG
KTIREVLREAFDYLFNLEKEMNDLYTKMGEVSQEEMEKMLNRTATIQDMLDHNDFYIIDAKIEEIARGLGIADIGLDKDV
SDLSGGQRTKILLAKLLLENPDILLLDEPTNYLDEDHIDWLKNYLKNYENAFILISHDIPFLNEVINLIYHVENKRLTRY
VGDYNEFRRVYEENKKRLEAAYERQQAEISKLEDFIAKNKARVSTVGMARSRQKKLDKIDKIELTKEKPKPEFNFKQARA
SGKVIFETKDLVIGYDSPLTKPLNIKMERGQKVALVGANGLGKTTLLKSLLGAIKPLEGDVTLGDYQYIGYFEQEERESN
YNTCIEEVWKEFPVFTQYEIRSALAKCGLTTKQLESKIVVLSGGEAAKVRLCKILNRETNILILDEPTNHLDVEAKEELK
RALREYKGSILLVCHEKEFYEDIVTETWNCESWTTKIV

Sequences:

>Translated_518_residues
MSILTVKDISHGFGDRAIFEEVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLMPDEGKIQWAKDVRVGYMDQHLNLTKG
KTIREVLREAFDYLFNLEKEMNDLYTKMGEVSQEEMEKMLNRTATIQDMLDHNDFYIIDAKIEEIARGLGIADIGLDKDV
SDLSGGQRTKILLAKLLLENPDILLLDEPTNYLDEDHIDWLKNYLKNYENAFILISHDIPFLNEVINLIYHVENKRLTRY
VGDYNEFRRVYEENKKRLEAAYERQQAEISKLEDFIAKNKARVSTVGMARSRQKKLDKIDKIELTKEKPKPEFNFKQARA
SGKVIFETKDLVIGYDSPLTKPLNIKMERGQKVALVGANGLGKTTLLKSLLGAIKPLEGDVTLGDYQYIGYFEQEERESN
YNTCIEEVWKEFPVFTQYEIRSALAKCGLTTKQLESKIVVLSGGEAAKVRLCKILNRETNILILDEPTNHLDVEAKEELK
RALREYKGSILLVCHEKEFYEDIVTETWNCESWTTKIV
>Mature_517_residues
SILTVKDISHGFGDRAIFEEVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLMPDEGKIQWAKDVRVGYMDQHLNLTKGK
TIREVLREAFDYLFNLEKEMNDLYTKMGEVSQEEMEKMLNRTATIQDMLDHNDFYIIDAKIEEIARGLGIADIGLDKDVS
DLSGGQRTKILLAKLLLENPDILLLDEPTNYLDEDHIDWLKNYLKNYENAFILISHDIPFLNEVINLIYHVENKRLTRYV
GDYNEFRRVYEENKKRLEAAYERQQAEISKLEDFIAKNKARVSTVGMARSRQKKLDKIDKIELTKEKPKPEFNFKQARAS
GKVIFETKDLVIGYDSPLTKPLNIKMERGQKVALVGANGLGKTTLLKSLLGAIKPLEGDVTLGDYQYIGYFEQEERESNY
NTCIEEVWKEFPVFTQYEIRSALAKCGLTTKQLESKIVVLSGGEAAKVRLCKILNRETNILILDEPTNHLDVEAKEELKR
ALREYKGSILLVCHEKEFYEDIVTETWNCESWTTKIV

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=509, Percent_Identity=28.6836935166994, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI27881506, Length=517, Percent_Identity=29.2069632495164, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI10947135, Length=518, Percent_Identity=29.3436293436293, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI10947137, Length=517, Percent_Identity=29.2069632495164, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI69354671, Length=518, Percent_Identity=29.3436293436293, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI90421313, Length=198, Percent_Identity=26.2626262626263, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI27262624, Length=212, Percent_Identity=26.4150943396226, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI27262626, Length=212, Percent_Identity=26.4150943396226, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1787041, Length=510, Percent_Identity=34.1176470588235, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1789751, Length=489, Percent_Identity=29.038854805726, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1787182, Length=524, Percent_Identity=31.2977099236641, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI2367384, Length=500, Percent_Identity=29, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI1789891, Length=278, Percent_Identity=25.5395683453237, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788165, Length=257, Percent_Identity=26.0700389105058, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87081782, Length=534, Percent_Identity=23.7827715355805, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788225, Length=191, Percent_Identity=28.7958115183246, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI48994943, Length=232, Percent_Identity=28.8793103448276, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789991, Length=505, Percent_Identity=23.1683168316832, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87081834, Length=206, Percent_Identity=22.8155339805825, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788506, Length=253, Percent_Identity=24.5059288537549, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788761, Length=178, Percent_Identity=29.2134831460674, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI48994883, Length=265, Percent_Identity=24.5283018867925, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=523, Percent_Identity=28.4894837476099, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17555318, Length=517, Percent_Identity=27.852998065764, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17553372, Length=511, Percent_Identity=30.1369863013699, Blast_Score=197, Evalue=9e-51,
Organism=Saccharomyces cerevisiae, GI6321121, Length=529, Percent_Identity=32.3251417769376, Blast_Score=245, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6320874, Length=523, Percent_Identity=28.2982791586998, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6325030, Length=399, Percent_Identity=26.8170426065163, Blast_Score=117, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6324314, Length=388, Percent_Identity=25.2577319587629, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6323278, Length=387, Percent_Identity=26.6149870801034, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24666836, Length=523, Percent_Identity=29.2543021032505, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI24641342, Length=508, Percent_Identity=28.740157480315, Blast_Score=202, Evalue=4e-52,
Organism=Drosophila melanogaster, GI24642252, Length=520, Percent_Identity=29.4230769230769, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI18859989, Length=520, Percent_Identity=29.4230769230769, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI24661270, Length=483, Percent_Identity=23.6024844720497, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355589, Length=483, Percent_Identity=23.6024844720497, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 59562; Mature: 59431

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILTVKDISHGFGDRAIFEEVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLMPDEGKI
CCEEEEEHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCE
QWAKDVRVGYMDQHLNLTKGKTIREVLREAFDYLFNLEKEMNDLYTKMGEVSQEEMEKML
EEECCCEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NRTATIQDMLDHNDFYIIDAKIEEIARGLGIADIGLDKDVSDLSGGQRTKILLAKLLLEN
HHHHHHHHHHCCCCEEEEECHHHHHHHCCCEEECCCCCCHHHCCCCCHHHHHHHHHHHCC
PDILLLDEPTNYLDEDHIDWLKNYLKNYENAFILISHDIPFLNEVINLIYHVENKRLTRY
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHH
VGDYNEFRRVYEENKKRLEAAYERQQAEISKLEDFIAKNKARVSTVGMARSRQKKLDKID
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KIELTKEKPKPEFNFKQARASGKVIFETKDLVIGYDSPLTKPLNIKMERGQKVALVGANG
CEEECCCCCCCCCCHHHHCCCCCEEEEECCEEEECCCCCCCCCEEEECCCCEEEEEECCC
LGKTTLLKSLLGAIKPLEGDVTLGDYQYIGYFEQEERESNYNTCIEEVWKEFPVFTQYEI
CCHHHHHHHHHHHCCCCCCCEEECCEEEECCCHHHHHCCHHHHHHHHHHHHCCCCCHHHH
RSALAKCGLTTKQLESKIVVLSGGEAAKVRLCKILNRETNILILDEPTNHLDVEAKEELK
HHHHHHCCCCHHHHCCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHH
RALREYKGSILLVCHEKEFYEDIVTETWNCESWTTKIV
HHHHHHCCCEEEEECCHHHHHHHHHCCCCCCCCEEECC
>Mature Secondary Structure 
SILTVKDISHGFGDRAIFEEVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLMPDEGKI
CEEEEEHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCE
QWAKDVRVGYMDQHLNLTKGKTIREVLREAFDYLFNLEKEMNDLYTKMGEVSQEEMEKML
EEECCCEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NRTATIQDMLDHNDFYIIDAKIEEIARGLGIADIGLDKDVSDLSGGQRTKILLAKLLLEN
HHHHHHHHHHCCCCEEEEECHHHHHHHCCCEEECCCCCCHHHCCCCCHHHHHHHHHHHCC
PDILLLDEPTNYLDEDHIDWLKNYLKNYENAFILISHDIPFLNEVINLIYHVENKRLTRY
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHH
VGDYNEFRRVYEENKKRLEAAYERQQAEISKLEDFIAKNKARVSTVGMARSRQKKLDKID
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KIELTKEKPKPEFNFKQARASGKVIFETKDLVIGYDSPLTKPLNIKMERGQKVALVGANG
CEEECCCCCCCCCCHHHHCCCCCEEEEECCEEEECCCCCCCCCEEEECCCCEEEEEECCC
LGKTTLLKSLLGAIKPLEGDVTLGDYQYIGYFEQEERESNYNTCIEEVWKEFPVFTQYEI
CCHHHHHHHHHHHCCCCCCCEEECCEEEECCCHHHHHCCHHHHHHHHHHHHCCCCCHHHH
RSALAKCGLTTKQLESKIVVLSGGEAAKVRLCKILNRETNILILDEPTNHLDVEAKEELK
HHHHHHCCCCHHHHCCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHH
RALREYKGSILLVCHEKEFYEDIVTETWNCESWTTKIV
HHHHHHCCCEEEEECCHHHHHHHHHCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]