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The map label for this gene is ykpA [H]

Identifier: 153937184

GI number: 153937184

Start: 1811856

End: 1813436

Strand: Reverse

Name: ykpA [H]

Synonym: CLC_1717

Alternate gene names: 153937184

Gene position: 1813436-1811856 (Counterclockwise)

Preceding gene: 153936709

Following gene: 153935385

Centisome position: 48.22

GC content: 31.12

Gene sequence:

>1581_bases
TTGATTACAGTAACAAATTTAAGTTTAAGATATGGGGACAAAAAACTTTTTGAAGATGTAAACCTTAAATTTACACCTGG
TAACTGCTATGGTGTTATAGGTGCTAATGGCGCCGGCAAGAGTACCTTTTTAAAAATTTTATCTGGAGAAATAGAAGCTA
ATACTGGAGATGTATCTATACAGCCGGGAGTTAGAATGTCTATTTTAAAACAAGATCACTTTAAATACGATGAATTTCCT
GTTTTAGAAACAGTTATAATGGGAAATGAAAGACTTTATGAAATAATGAAAGAAAAAGATGCTATATATGCTAAAACTCC
TTTTACAGATGAAGATGGCATAAAAGCCTCTGAACTAGAGGGAGAATTTGCAGACTTAAACGGTTGGGAAGCGGAAGCAG
AAGCTTCATCCTTACTTCAAGGCTTAGGAATAGGCACAGAGCTTCACGAAAAAAATATGAAGGATTTATCCGGTAGCGAA
AAGGTAAAAGTATTACTAGCTCAGGCATTATTCGGTAATCCCGGAGTTCTTATACTAGATGAGCCTACTAACCACTTAGA
TATAAAATCTGTGAACTGGCTTGAAGAATTTTTAATAAATTTTGAAGGAACAGTTATTGTAGTATCCCATGATAGACATT
TCTTAAATAAAGTATGTACTCACATGGCAGATGTTGACTTTGGTAAAATTAAATTATATGTAGGAAACTATGATTTTTGG
TATGAATCTAGCCAATTAGCGCTTCAAATGGCTAAAGATCAAAACAAGAAAAAAGAAGAAAAAATAAAAGAGCTACAGGA
ATTCATTGCTCGTTTTAGTGCTAATGCATCTAAATCTAAGCAAGCCACTTCCCGTAAAAAATTATTAGATAAAATCGATT
TAGATAACATACAACCTTCTAGTAGAAAGTATCCTTACATAGCCTTTAAACCCGAAAGAAAAGTTGGTAATGATATATTA
AGAGTAGAGGGTTTAACTAAAACTATAGACGGAACAAAAATATTAGATAATATAAGCTTTATAATAGGTAAAGATGATAA
AATAGCTTTTGTAGGAGATGAATTATCTATAACTACTCTATTTAAAATAATATCTGGTGAATTAGAGCCAGATAGTGGTG
AATATAAATGGGGAATAACTATAACAAATGCTTATTTCCCAAAGGATAATTCCGAATACTTTAATGATGTAGATTTAAAT
TTAGTAGATTGGTTAAGACAATACTCCGAAGAAAAATCTGAAAGCTATCTACGTGGATTCTTAGGAAGGATGCTATTCTC
TGGTGAAGAGGCTTTAAAAGAGGTTAAAGTTCTATCTGGTGGAGAAAAAGTTAGATGTATGCTATCAAAAATGATGCTAA
ATAATGCTAATGTAATTATATTAGATCAACCAACTAACCACTTAGACCTAGAATCTATAACTGCACTAAATAATGGTTTA
ATGGACTATAAGAGTAACATATTATTTACTTCTCATGACCATCAATTTATACAAACTATAGCCAATAGAATTATAGAAGT
ATCTGAAGCAAAATTTGTTGATAAAAAGGTTACTTATGATGAATATTTAGAAAGCAAATAA

Upstream 100 bases:

>100_bases
TTGAAAAGTTTGAAAGATTAACAAATACCTTCTTTTTAAATGGCTTATTTTATGGTATAATGTCGCGAGAACATAAATTT
TAGTAAAGGATGGTATAGAC

Downstream 100 bases:

>100_bases
AAAACTATTTTGAAAATAAAAATCATAAAATCTAGAATGTATAACTAAATATATCAAAAACACTATCAATTTATTAAAAT
TTGATAGTGTTTATTTTTAA

Product: putative drug resistance ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MITVTNLSLRYGDKKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILSGEIEANTGDVSIQPGVRMSILKQDHFKYDEFP
VLETVIMGNERLYEIMKEKDAIYAKTPFTDEDGIKASELEGEFADLNGWEAEAEASSLLQGLGIGTELHEKNMKDLSGSE
KVKVLLAQALFGNPGVLILDEPTNHLDIKSVNWLEEFLINFEGTVIVVSHDRHFLNKVCTHMADVDFGKIKLYVGNYDFW
YESSQLALQMAKDQNKKKEEKIKELQEFIARFSANASKSKQATSRKKLLDKIDLDNIQPSSRKYPYIAFKPERKVGNDIL
RVEGLTKTIDGTKILDNISFIIGKDDKIAFVGDELSITTLFKIISGELEPDSGEYKWGITITNAYFPKDNSEYFNDVDLN
LVDWLRQYSEEKSESYLRGFLGRMLFSGEEALKEVKVLSGGEKVRCMLSKMMLNNANVIILDQPTNHLDLESITALNNGL
MDYKSNILFTSHDHQFIQTIANRIIEVSEAKFVDKKVTYDEYLESK

Sequences:

>Translated_526_residues
MITVTNLSLRYGDKKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILSGEIEANTGDVSIQPGVRMSILKQDHFKYDEFP
VLETVIMGNERLYEIMKEKDAIYAKTPFTDEDGIKASELEGEFADLNGWEAEAEASSLLQGLGIGTELHEKNMKDLSGSE
KVKVLLAQALFGNPGVLILDEPTNHLDIKSVNWLEEFLINFEGTVIVVSHDRHFLNKVCTHMADVDFGKIKLYVGNYDFW
YESSQLALQMAKDQNKKKEEKIKELQEFIARFSANASKSKQATSRKKLLDKIDLDNIQPSSRKYPYIAFKPERKVGNDIL
RVEGLTKTIDGTKILDNISFIIGKDDKIAFVGDELSITTLFKIISGELEPDSGEYKWGITITNAYFPKDNSEYFNDVDLN
LVDWLRQYSEEKSESYLRGFLGRMLFSGEEALKEVKVLSGGEKVRCMLSKMMLNNANVIILDQPTNHLDLESITALNNGL
MDYKSNILFTSHDHQFIQTIANRIIEVSEAKFVDKKVTYDEYLESK
>Mature_526_residues
MITVTNLSLRYGDKKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILSGEIEANTGDVSIQPGVRMSILKQDHFKYDEFP
VLETVIMGNERLYEIMKEKDAIYAKTPFTDEDGIKASELEGEFADLNGWEAEAEASSLLQGLGIGTELHEKNMKDLSGSE
KVKVLLAQALFGNPGVLILDEPTNHLDIKSVNWLEEFLINFEGTVIVVSHDRHFLNKVCTHMADVDFGKIKLYVGNYDFW
YESSQLALQMAKDQNKKKEEKIKELQEFIARFSANASKSKQATSRKKLLDKIDLDNIQPSSRKYPYIAFKPERKVGNDIL
RVEGLTKTIDGTKILDNISFIIGKDDKIAFVGDELSITTLFKIISGELEPDSGEYKWGITITNAYFPKDNSEYFNDVDLN
LVDWLRQYSEEKSESYLRGFLGRMLFSGEEALKEVKVLSGGEKVRCMLSKMMLNNANVIILDQPTNHLDLESITALNNGL
MDYKSNILFTSHDHQFIQTIANRIIEVSEAKFVDKKVTYDEYLESK

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=530, Percent_Identity=29.0566037735849, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI27881506, Length=539, Percent_Identity=31.7254174397032, Blast_Score=243, Evalue=4e-64,
Organism=Homo sapiens, GI10947137, Length=539, Percent_Identity=31.7254174397032, Blast_Score=243, Evalue=4e-64,
Organism=Homo sapiens, GI69354671, Length=533, Percent_Identity=28.1425891181989, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI10947135, Length=533, Percent_Identity=28.1425891181989, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI105990541, Length=204, Percent_Identity=27.4509803921569, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI1787041, Length=528, Percent_Identity=44.8863636363636, Blast_Score=498, Evalue=1e-142,
Organism=Escherichia coli, GI1789751, Length=517, Percent_Identity=31.7214700193424, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI2367384, Length=522, Percent_Identity=30.4597701149425, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1787182, Length=505, Percent_Identity=30.0990099009901, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI1787029, Length=246, Percent_Identity=24.7967479674797, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786398, Length=238, Percent_Identity=24.3697478991597, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786872, Length=245, Percent_Identity=26.9387755102041, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=519, Percent_Identity=30.635838150289, Blast_Score=225, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI17559834, Length=511, Percent_Identity=27.5929549902153, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17555318, Length=511, Percent_Identity=26.027397260274, Blast_Score=198, Evalue=7e-51,
Organism=Caenorhabditis elegans, GI17558664, Length=216, Percent_Identity=25.462962962963, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=520, Percent_Identity=31.9230769230769, Blast_Score=239, Evalue=9e-64,
Organism=Saccharomyces cerevisiae, GI6321121, Length=530, Percent_Identity=29.4339622641509, Blast_Score=221, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6325030, Length=248, Percent_Identity=30.6451612903226, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324314, Length=373, Percent_Identity=26.8096514745308, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6323278, Length=373, Percent_Identity=25.7372654155496, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24666836, Length=513, Percent_Identity=30.4093567251462, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24642252, Length=538, Percent_Identity=28.2527881040892, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI18859989, Length=538, Percent_Identity=28.2527881040892, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24641342, Length=518, Percent_Identity=29.5366795366795, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI116007184, Length=247, Percent_Identity=25.1012145748988, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221500365, Length=247, Percent_Identity=25.1012145748988, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 59494; Mature: 59494

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVTNLSLRYGDKKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILSGEIEANTGDVSI
CEEEEEEEEECCCHHHHHCCCEEECCCCEEEEEECCCCCHHHHHHHHCCCEECCCCCEEE
QPGVRMSILKQDHFKYDEFPVLETVIMGNERLYEIMKEKDAIYAKTPFTDEDGIKASELE
CCCCEEEHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCCCCCHHHCC
GEFADLNGWEAEAEASSLLQGLGIGTELHEKNMKDLSGSEKVKVLLAQALFGNPGVLILD
CCCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCHHHCCCCHHHHHHHHHHHCCCCCEEEEC
EPTNHLDIKSVNWLEEFLINFEGTVIVVSHDRHFLNKVCTHMADVDFGKIKLYVGNYDFW
CCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEE
YESSQLALQMAKDQNKKKEEKIKELQEFIARFSANASKSKQATSRKKLLDKIDLDNIQPS
ECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC
SRKYPYIAFKPERKVGNDILRVEGLTKTIDGTKILDNISFIIGKDDKIAFVGDELSITTL
CCCCCEEEECCCHHCCCCEEEECCCCCCCCCHHHHCCCEEEEECCCEEEEECCCCHHHHH
FKIISGELEPDSGEYKWGITITNAYFPKDNSEYFNDVDLNLVDWLRQYSEEKSESYLRGF
HHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LGRMLFSGEEALKEVKVLSGGEKVRCMLSKMMLNNANVIILDQPTNHLDLESITALNNGL
HHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCC
MDYKSNILFTSHDHQFIQTIANRIIEVSEAKFVDKKVTYDEYLESK
HHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MITVTNLSLRYGDKKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILSGEIEANTGDVSI
CEEEEEEEEECCCHHHHHCCCEEECCCCEEEEEECCCCCHHHHHHHHCCCEECCCCCEEE
QPGVRMSILKQDHFKYDEFPVLETVIMGNERLYEIMKEKDAIYAKTPFTDEDGIKASELE
CCCCEEEHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCCCCCHHHCC
GEFADLNGWEAEAEASSLLQGLGIGTELHEKNMKDLSGSEKVKVLLAQALFGNPGVLILD
CCCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCHHHCCCCHHHHHHHHHHHCCCCCEEEEC
EPTNHLDIKSVNWLEEFLINFEGTVIVVSHDRHFLNKVCTHMADVDFGKIKLYVGNYDFW
CCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEE
YESSQLALQMAKDQNKKKEEKIKELQEFIARFSANASKSKQATSRKKLLDKIDLDNIQPS
ECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC
SRKYPYIAFKPERKVGNDILRVEGLTKTIDGTKILDNISFIIGKDDKIAFVGDELSITTL
CCCCCEEEECCCHHCCCCEEEECCCCCCCCCHHHHCCCEEEEECCCEEEEECCCCHHHHH
FKIISGELEPDSGEYKWGITITNAYFPKDNSEYFNDVDLNLVDWLRQYSEEKSESYLRGF
HHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LGRMLFSGEEALKEVKVLSGGEKVRCMLSKMMLNNANVIILDQPTNHLDLESITALNNGL
HHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCC
MDYKSNILFTSHDHQFIQTIANRIIEVSEAKFVDKKVTYDEYLESK
HHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]