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The map label for this gene is queC

Identifier: 153936103

GI number: 153936103

Start: 1660613

End: 1661272

Strand: Direct

Name: queC

Synonym: CLC_1589

Alternate gene names: 153936103

Gene position: 1660613-1661272 (Clockwise)

Preceding gene: 153935134

Following gene: 153937363

Centisome position: 44.16

GC content: 29.7

Gene sequence:

>660_bases
ATGAATAAGGAAAAAGCAATAGTAGTATTTAGTGGTGGACAAGATAGTACAACCTGTTTGTTTTGGGCAAAGAAAAAATA
TAAAGAAGTTATAGCAGTATCCTTTGATTATAATCAAAAACATAAATTAGAGTTAGACTGTGCAAAGGATATATGTAAAA
AATATAATATTGAACATCATATTTTAGATTTAAATTTGTTAAATCAATTAGCACCAAATTCACTAACTAGGCAGGATATA
ACTGTTGATAAAAGCGCACCTAAAGAAGGGGTGCCTAATTCCTTTGTAGATGGAAGAAATTTATTGTTTTTAAGCTTTGT
CGCAGTATTTGCAAAACAAAAAGGAATAAACACTATTATAACTGGTGTGTCACAGAGTGATTTTAGTGGATATCCAGATT
GTAGAGATGTATTTATAAAATCTTTAAATGTTACATTAAATTTAGCTATGGATTATGAATTTGAAATAATTACACCACTA
ATGTGGATCAATAAAGCAGAAACGTGGAAAATGGCTTATGATTTAGGGGTTCTTGATATCGTTAAAGAAGAAACCTTAAC
ATGCTACAATGGAATAAAAGCAGATGGATGTGGGGAATGTCCAGCTTGTAAATTAAGAAAAAAGGGATATTGGGAGTTTG
AAAAAGAGTATTTAAAATAG

Upstream 100 bases:

>100_bases
AACAGTTTATATAAAGAGAGTGTATTAAAGAAGCATAACTATAACAAAGATTTTTGTAGATTGTAGGATGATAATAAAAT
AATAAAGGGATGTGTAGTAG

Downstream 100 bases:

>100_bases
TAATTTTATATGTGTTGCTTGAGCAATACCTCCTTTTTATATTTCGTATTTAGTTTTTGTAAATTTTGTCGATAATTTAA
TATTAGAAGTATGAAATATT

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MNKEKAIVVFSGGQDSTTCLFWAKKKYKEVIAVSFDYNQKHKLELDCAKDICKKYNIEHHILDLNLLNQLAPNSLTRQDI
TVDKSAPKEGVPNSFVDGRNLLFLSFVAVFAKQKGINTIITGVSQSDFSGYPDCRDVFIKSLNVTLNLAMDYEFEIITPL
MWINKAETWKMAYDLGVLDIVKEETLTCYNGIKADGCGECPACKLRKKGYWEFEKEYLK

Sequences:

>Translated_219_residues
MNKEKAIVVFSGGQDSTTCLFWAKKKYKEVIAVSFDYNQKHKLELDCAKDICKKYNIEHHILDLNLLNQLAPNSLTRQDI
TVDKSAPKEGVPNSFVDGRNLLFLSFVAVFAKQKGINTIITGVSQSDFSGYPDCRDVFIKSLNVTLNLAMDYEFEIITPL
MWINKAETWKMAYDLGVLDIVKEETLTCYNGIKADGCGECPACKLRKKGYWEFEKEYLK
>Mature_219_residues
MNKEKAIVVFSGGQDSTTCLFWAKKKYKEVIAVSFDYNQKHKLELDCAKDICKKYNIEHHILDLNLLNQLAPNSLTRQDI
TVDKSAPKEGVPNSFVDGRNLLFLSFVAVFAKQKGINTIITGVSQSDFSGYPDCRDVFIKSLNVTLNLAMDYEFEIITPL
MWINKAETWKMAYDLGVLDIVKEETLTCYNGIKADGCGECPACKLRKKGYWEFEKEYLK

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=210, Percent_Identity=55.2380952380952, Blast_Score=239, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_CLOB1 (A7FU68)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001383901.1
- ProteinModelPortal:   A7FU68
- SMR:   A7FU68
- STRING:   A7FU68
- GeneID:   5397474
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_1578
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- ProtClustDB:   CLSK883558
- BioCyc:   CBOT441770:CLB_1578-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 24950; Mature: 24950

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKEKAIVVFSGGQDSTTCLFWAKKKYKEVIAVSFDYNQKHKLELDCAKDICKKYNIEHH
CCCCCEEEEEECCCCCEEEEEEEHHHCCEEEEEEECCCCCEEEEHHHHHHHHHHCCCCCE
ILDLNLLNQLAPNSLTRQDITVDKSAPKEGVPNSFVDGRNLLFLSFVAVFAKQKGINTII
EEHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
TGVSQSDFSGYPDCRDVFIKSLNVTLNLAMDYEFEIITPLMWINKAETWKMAYDLGVLDI
ECCCCCCCCCCCCHHHHHHHHCCEEEEEEEECCEEEECHHHHCCCCCCEEEEHHCCHHHH
VKEETLTCYNGIKADGCGECPACKLRKKGYWEFEKEYLK
HHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCHHHHHHCC
>Mature Secondary Structure
MNKEKAIVVFSGGQDSTTCLFWAKKKYKEVIAVSFDYNQKHKLELDCAKDICKKYNIEHH
CCCCCEEEEEECCCCCEEEEEEEHHHCCEEEEEEECCCCCEEEEHHHHHHHHHHCCCCCE
ILDLNLLNQLAPNSLTRQDITVDKSAPKEGVPNSFVDGRNLLFLSFVAVFAKQKGINTII
EEHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
TGVSQSDFSGYPDCRDVFIKSLNVTLNLAMDYEFEIITPLMWINKAETWKMAYDLGVLDI
ECCCCCCCCCCCCHHHHHHHHCCEEEEEEEECCEEEECHHHHCCCCCCEEEEHHCCHHHH
VKEETLTCYNGIKADGCGECPACKLRKKGYWEFEKEYLK
HHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA