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The map label for this gene is ppnK

Identifier: 153935423

GI number: 153935423

Start: 1935697

End: 1936542

Strand: Reverse

Name: ppnK

Synonym: CLC_1823

Alternate gene names: 153935423

Gene position: 1936542-1935697 (Counterclockwise)

Preceding gene: 153936268

Following gene: 153936006

Centisome position: 51.5

GC content: 29.67

Gene sequence:

>846_bases
ATGAAAAATATTGGTATAAATATAAATACAGATAAGGATATAAGTAGAAACATTTTAGACAAAATTTTTCAGTATATACA
TGAGGAATGTAGTGAAGCTAAAATAAAGGTTTTTTATGATTCTAAAGGTTTAGATAATGAAGAAAGTAGAGCATTAGATG
CGGTCATGGTACTAGGAGGAGATGGTACTATTTTAGGTACTGCTAGAGCCTTAGCCAAATATGATGTCCCTATATTTGGA
ATAAATAGAGGGCATTTAGGTTTTTTAGCAGAGATAGAGCTAGAAGACTGTAAAAAGGCTATAAAAAATCTATTTAAAGG
TCAATATAAAATAGAGGATAGAATAATGCTAAAATGTGACTTAAAGGGAATAGACAAGAAAGATGATTTTTTAGCATTAA
ATGATATAGTGCTTACAAAAGGAAATTTATCACGAATAGTAAAATATAGCATATATGTAGATGATGTATGGTATACAACT
TTTGTAGCAGATGGAGTCATTGTAGCTACGCCTACGGGATCTACAGCCTACTCTTTATCTGCAGGAGGACCAATAGTATA
TCCAGATCTAGATGTATTAGAGATTGCGCCAATTTGTCCTCACTCTTTAGGAATTAGACCCATATTGCTAAATGGCAATA
GTAAAATTAATATAAGGGTTTTAAAAAAATATGAGGATCCTGTACTTACTATCGATGGTCAAAGATATAAGAAAGTAACA
GTAAATGAGGTTACCATAAGTAAATCTGAATATAAATGTAGACTTATAAAATTTAAAGATAAGGATTATTTTAAAATATT
AAGAACTAAAATATCTTATAGATCTAGAGAATGTGAAGGTGAATAA

Upstream 100 bases:

>100_bases
TATATATGACAAAAAATAAAGGGGTAAATAGTGATTTTCAAGATGACTATGTAGATTATATAGTAAATAAAGCTCATAAT
AATTTGAATGGTGATAAATA

Downstream 100 bases:

>100_bases
TATGAAAGTTTCAAGACATGCTAAAATTTTAGAAATAATAAATTCTAAAGATATAGATACCCAAGAGGAACTAGCAGAAG
AATTAAAGAAAATGGGAATG

Product: ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKNIGININTDKDISRNILDKIFQYIHEECSEAKIKVFYDSKGLDNEESRALDAVMVLGGDGTILGTARALAKYDVPIFG
INRGHLGFLAEIELEDCKKAIKNLFKGQYKIEDRIMLKCDLKGIDKKDDFLALNDIVLTKGNLSRIVKYSIYVDDVWYTT
FVADGVIVATPTGSTAYSLSAGGPIVYPDLDVLEIAPICPHSLGIRPILLNGNSKINIRVLKKYEDPVLTIDGQRYKKVT
VNEVTISKSEYKCRLIKFKDKDYFKILRTKISYRSRECEGE

Sequences:

>Translated_281_residues
MKNIGININTDKDISRNILDKIFQYIHEECSEAKIKVFYDSKGLDNEESRALDAVMVLGGDGTILGTARALAKYDVPIFG
INRGHLGFLAEIELEDCKKAIKNLFKGQYKIEDRIMLKCDLKGIDKKDDFLALNDIVLTKGNLSRIVKYSIYVDDVWYTT
FVADGVIVATPTGSTAYSLSAGGPIVYPDLDVLEIAPICPHSLGIRPILLNGNSKINIRVLKKYEDPVLTIDGQRYKKVT
VNEVTISKSEYKCRLIKFKDKDYFKILRTKISYRSRECEGE
>Mature_281_residues
MKNIGININTDKDISRNILDKIFQYIHEECSEAKIKVFYDSKGLDNEESRALDAVMVLGGDGTILGTARALAKYDVPIFG
INRGHLGFLAEIELEDCKKAIKNLFKGQYKIEDRIMLKCDLKGIDKKDDFLALNDIVLTKGNLSRIVKYSIYVDDVWYTT
FVADGVIVATPTGSTAYSLSAGGPIVYPDLDVLEIAPICPHSLGIRPILLNGNSKINIRVLKKYEDPVLTIDGQRYKKVT
VNEVTISKSEYKCRLIKFKDKDYFKILRTKISYRSRECEGE

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family

Homologues:

Organism=Homo sapiens, GI55743112, Length=260, Percent_Identity=26.9230769230769, Blast_Score=91, Evalue=9e-19,
Organism=Escherichia coli, GI1788968, Length=271, Percent_Identity=33.9483394833948, Blast_Score=181, Evalue=6e-47,
Organism=Saccharomyces cerevisiae, GI6320794, Length=266, Percent_Identity=30.8270676691729, Blast_Score=135, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6325068, Length=265, Percent_Identity=32.4528301886792, Blast_Score=131, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6322509, Length=267, Percent_Identity=28.8389513108614, Blast_Score=124, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28573828, Length=267, Percent_Identity=26.9662921348315, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573832, Length=267, Percent_Identity=26.9662921348315, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573830, Length=267, Percent_Identity=26.9662921348315, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI161077047, Length=267, Percent_Identity=26.9662921348315, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573826, Length=267, Percent_Identity=26.9662921348315, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20129957, Length=311, Percent_Identity=23.4726688102894, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24653422, Length=311, Percent_Identity=23.4726688102894, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281363323, Length=311, Percent_Identity=23.4726688102894, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281363321, Length=311, Percent_Identity=23.4726688102894, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24653424, Length=311, Percent_Identity=23.4726688102894, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPNK_CLOB1 (A7FUT5)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001384138.1
- ProteinModelPortal:   A7FUT5
- SMR:   A7FUT5
- STRING:   A7FUT5
- GeneID:   5396379
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_1816
- eggNOG:   COG0061
- HOGENOM:   HBG713904
- OMA:   LNEMVLH
- ProtClustDB:   CLSK961137
- BioCyc:   CBOT441770:CLB_1816-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00361
- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504
- Gene3D:   G3DSA:2.60.200.30
- Gene3D:   G3DSA:3.40.50.10330
- PANTHER:   PTHR20275

Pfam domain/function: PF01513 NAD_kinase; SSF111331 ATP-NAD_kinase_PpnK-typ

EC number: =2.7.1.23

Molecular weight: Translated: 31690; Mature: 31690

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIGININTDKDISRNILDKIFQYIHEECSEAKIKVFYDSKGLDNEESRALDAVMVLGG
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCEEEEEEECC
DGTILGTARALAKYDVPIFGINRGHLGFLAEIELEDCKKAIKNLFKGQYKIEDRIMLKCD
CCEEEEHHHHHHHCCCEEEEECCCCEEEEEEEEHHHHHHHHHHHHCCCEEECCEEEEEEE
LKGIDKKDDFLALNDIVLTKGNLSRIVKYSIYVDDVWYTTFVADGVIVATPTGSTAYSLS
CCCCCCCCCEEEEEEEEEECCCHHEEEEEEEEEECCEEEEEHHCCEEEEECCCCCEEEEC
AGGPIVYPDLDVLEIAPICPHSLGIRPILLNGNSKINIRVLKKYEDPVLTIDGQRYKKVT
CCCCEEECCCCCEEECCCCCCCCCCEEEEECCCCEEEEEEEEECCCCEEEECCCCEEEEE
VNEVTISKSEYKCRLIKFKDKDYFKILRTKISYRSRECEGE
EEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKNIGININTDKDISRNILDKIFQYIHEECSEAKIKVFYDSKGLDNEESRALDAVMVLGG
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCEEEEEEECC
DGTILGTARALAKYDVPIFGINRGHLGFLAEIELEDCKKAIKNLFKGQYKIEDRIMLKCD
CCEEEEHHHHHHHCCCEEEEECCCCEEEEEEEEHHHHHHHHHHHHCCCEEECCEEEEEEE
LKGIDKKDDFLALNDIVLTKGNLSRIVKYSIYVDDVWYTTFVADGVIVATPTGSTAYSLS
CCCCCCCCCEEEEEEEEEECCCHHEEEEEEEEEECCEEEEEHHCCEEEEECCCCCEEEEC
AGGPIVYPDLDVLEIAPICPHSLGIRPILLNGNSKINIRVLKKYEDPVLTIDGQRYKKVT
CCCCEEECCCCCEEECCCCCCCCCCEEEEECCCCEEEEEEEEECCCCEEEECCCCEEEEE
VNEVTISKSEYKCRLIKFKDKDYFKILRTKISYRSRECEGE
EEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA