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The map label for this gene is nuoG [C]

Identifier: 153935257

GI number: 153935257

Start: 1898579

End: 1900312

Strand: Reverse

Name: nuoG [C]

Synonym: CLC_1790

Alternate gene names: 153935257

Gene position: 1900312-1898579 (Counterclockwise)

Preceding gene: 153936195

Following gene: 153937826

Centisome position: 50.53

GC content: 33.16

Gene sequence:

>1734_bases
ATGAGTTTAGTAACTTTAAATATAAATGGTAAAGATCTTAAAGTAGAAAATGGAACTACTATATTAGATGCAGCAAAACT
TTTAAATATAAATATACCAACTCTATGTAATTTTCATCTTAATGATAATAAAACAGAAAATAAACCTGGTTCCTGTAGGG
TCTGTGTAGTAGAAGTAGAAGGGAGAAAAAACTTAGCGCCAGCATGTTGTACCCCTGTAGGGGAAGGAATGATAGTAAAA
ACTAATTCCATAAGGGCTATAAAAGCTAGAAGAGCTATAGTAGAATTACTTTTATCTGATCATCCAAAAGACTGTTTGCT
TTGTGAGAAAAATACAAAATGTGAGCTACAAAAATTAGCTGCAGATATGGGTATAAGAGAAATGAAATATCAAGGTGATG
TTTCAATGTATCCTATAGATATTTCTAGCTATTCCATAGTTAGGGATATGGATAAATGTATACTTTGTAGAAGATGCATA
ACTATATGTAATGAAGTTCAAACTGTAGGAACCCTATCTGCTATTGGAAGAGGTTTTGAAACTGTAGTAGCACCAGCCTT
TTCTGAAGCTATAAAAAATACTAATTGTACTTTCTGTGGACAATGTGTTTCTGTCTGTCCAACTGGGGCTTTAACAGAAG
TAAATAATACAAGTAAAGTTTGGGATGCTCTATCACAAAAGGATAAAATTGTTATTGTACAAACAGCTCCAGCTATTAGA
GCTGCTTTAGGTGAAGAATTTGGATTAGAACCTGGAACAACTGTTACAGGAAAAATGGTAGCGGCTCTTCGTCAATTAGG
ATTCAGTAAAGTTTTTGATACAGATTTTGCAGCAGACTTGACTATTATGGAGGAAGCTTCAGAATTTATTCATAGATTAG
AACATGGCGGAACACTTCCAATGCTTACAAGTTGTTGTCCAGGATGGATAAAATTCTTTGAACACAACTTTAATGATTTA
ATGGATATACCATCTAGTTGTAAATCACCTCAGCAAATGTTTGGAGCTATAGCTAAAAGTTATTTAGCAGAAAAAATGAA
GGTAGATCCTAAAGATATTATAGTAGTATCTGTAATGCCTTGTCTTGCTAAAAAGTATGAGGCAAAAAGAGAAGAAATGA
AGAGAAATGGAATCCCTGATGTTGATATTGTTATAAGTACAAGAGAATTAGCTAAAATGATAGTAGAAGCGGGTATAGAT
TTTAATTCTCTACAGGAGGAAGAATTTGATAATCCCCTAGGTGAATCTACAGGGGCTTCAGTAATTTTTGGAACTACCGG
CGGTGTTATGGAAGCGGCTTTAAGAACTGCCTATGAATGGGTTACTAAAGGTACTTTAAAAGATGTAGAATTTATAGAAG
TTCGCGGTGAAGATGGTATAAGAGAAGCTACAGTAAACATAAAGGATACAGAGGTTAAAGTAGCTATAGCTAGTGGATTA
GGTAATGCTAGAAAGCTTTTAAATGATATAAGAAATGGAAAGTCTAAATATCATATGATCGAAATCATGGCGTGTCCATC
AGGATGTGTAGATGGTGGTGGTCAACCTTATATCTATGGAGATACAAATATATTGAAAAAAAGAACAGAAGCCCTATATA
AAGAAGATAGTAATAAAGAAATAAGGAAGTCTCACGAAAATCCATATATAAAGAAACTTTATGAAGAATATTTAGGTAAA
CCTTATGGTGAAAAAGCTCATGAACTTCTTCATACTAAATATAGAGTTAGATAA

Upstream 100 bases:

>100_bases
CATTTTATAAATCAAGAAAAATGTATTAAATGTGGAAATTGTTATAGCGCTTGTCCAGTTGGGGCTATTATAAAGAAATA
GGAAGAAAGAGGTGAATAAA

Downstream 100 bases:

>100_bases
CATGAAATAAACACAAATTTTCCTATTAATATACACCAAATAAAACCAGTATCAGTATGGTTTGAAACTATAATCAGTTA
TAAGTTTAAAGTAATTTCAT

Product: [Fe] hydrogenase

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 577; Mature: 576

Protein sequence:

>577_residues
MSLVTLNINGKDLKVENGTTILDAAKLLNINIPTLCNFHLNDNKTENKPGSCRVCVVEVEGRKNLAPACCTPVGEGMIVK
TNSIRAIKARRAIVELLLSDHPKDCLLCEKNTKCELQKLAADMGIREMKYQGDVSMYPIDISSYSIVRDMDKCILCRRCI
TICNEVQTVGTLSAIGRGFETVVAPAFSEAIKNTNCTFCGQCVSVCPTGALTEVNNTSKVWDALSQKDKIVIVQTAPAIR
AALGEEFGLEPGTTVTGKMVAALRQLGFSKVFDTDFAADLTIMEEASEFIHRLEHGGTLPMLTSCCPGWIKFFEHNFNDL
MDIPSSCKSPQQMFGAIAKSYLAEKMKVDPKDIIVVSVMPCLAKKYEAKREEMKRNGIPDVDIVISTRELAKMIVEAGID
FNSLQEEEFDNPLGESTGASVIFGTTGGVMEAALRTAYEWVTKGTLKDVEFIEVRGEDGIREATVNIKDTEVKVAIASGL
GNARKLLNDIRNGKSKYHMIEIMACPSGCVDGGGQPYIYGDTNILKKRTEALYKEDSNKEIRKSHENPYIKKLYEEYLGK
PYGEKAHELLHTKYRVR

Sequences:

>Translated_577_residues
MSLVTLNINGKDLKVENGTTILDAAKLLNINIPTLCNFHLNDNKTENKPGSCRVCVVEVEGRKNLAPACCTPVGEGMIVK
TNSIRAIKARRAIVELLLSDHPKDCLLCEKNTKCELQKLAADMGIREMKYQGDVSMYPIDISSYSIVRDMDKCILCRRCI
TICNEVQTVGTLSAIGRGFETVVAPAFSEAIKNTNCTFCGQCVSVCPTGALTEVNNTSKVWDALSQKDKIVIVQTAPAIR
AALGEEFGLEPGTTVTGKMVAALRQLGFSKVFDTDFAADLTIMEEASEFIHRLEHGGTLPMLTSCCPGWIKFFEHNFNDL
MDIPSSCKSPQQMFGAIAKSYLAEKMKVDPKDIIVVSVMPCLAKKYEAKREEMKRNGIPDVDIVISTRELAKMIVEAGID
FNSLQEEEFDNPLGESTGASVIFGTTGGVMEAALRTAYEWVTKGTLKDVEFIEVRGEDGIREATVNIKDTEVKVAIASGL
GNARKLLNDIRNGKSKYHMIEIMACPSGCVDGGGQPYIYGDTNILKKRTEALYKEDSNKEIRKSHENPYIKKLYEEYLGK
PYGEKAHELLHTKYRVR
>Mature_576_residues
SLVTLNINGKDLKVENGTTILDAAKLLNINIPTLCNFHLNDNKTENKPGSCRVCVVEVEGRKNLAPACCTPVGEGMIVKT
NSIRAIKARRAIVELLLSDHPKDCLLCEKNTKCELQKLAADMGIREMKYQGDVSMYPIDISSYSIVRDMDKCILCRRCIT
ICNEVQTVGTLSAIGRGFETVVAPAFSEAIKNTNCTFCGQCVSVCPTGALTEVNNTSKVWDALSQKDKIVIVQTAPAIRA
ALGEEFGLEPGTTVTGKMVAALRQLGFSKVFDTDFAADLTIMEEASEFIHRLEHGGTLPMLTSCCPGWIKFFEHNFNDLM
DIPSSCKSPQQMFGAIAKSYLAEKMKVDPKDIIVVSVMPCLAKKYEAKREEMKRNGIPDVDIVISTRELAKMIVEAGIDF
NSLQEEEFDNPLGESTGASVIFGTTGGVMEAALRTAYEWVTKGTLKDVEFIEVRGEDGIREATVNIKDTEVKVAIASGLG
NARKLLNDIRNGKSKYHMIEIMACPSGCVDGGGQPYIYGDTNILKKRTEALYKEDSNKEIRKSHENPYIKKLYEEYLGKP
YGEKAHELLHTKYRVR

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI11968051, Length=402, Percent_Identity=29.8507462686567, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI6912524, Length=402, Percent_Identity=28.1094527363184, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI134284357, Length=363, Percent_Identity=28.9256198347107, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI84452151, Length=363, Percent_Identity=28.9256198347107, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI14165461, Length=450, Percent_Identity=26.8888888888889, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI33519475, Length=224, Percent_Identity=30.3571428571429, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI145693161, Length=246, Percent_Identity=26.0162601626016, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71995015, Length=403, Percent_Identity=31.2655086848635, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17565758, Length=225, Percent_Identity=32.4444444444444, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI32566231, Length=225, Percent_Identity=31.5555555555556, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI193209088, Length=229, Percent_Identity=32.3144104803493, Blast_Score=114, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324089, Length=394, Percent_Identity=25.3807106598985, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI116007470, Length=373, Percent_Identity=31.3672922252011, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI116007466, Length=373, Percent_Identity=31.3672922252011, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI116007464, Length=373, Percent_Identity=31.3672922252011, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI116007468, Length=373, Percent_Identity=31.3672922252011, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI116007462, Length=287, Percent_Identity=33.4494773519164, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24640559, Length=205, Percent_Identity=33.6585365853659, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24640557, Length=205, Percent_Identity=33.6585365853659, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 63695; Mature: 63564

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVTLNINGKDLKVENGTTILDAAKLLNINIPTLCNFHLNDNKTENKPGSCRVCVVEVE
CEEEEEEECCCEEEECCCCCCEEHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEC
GRKNLAPACCTPVGEGMIVKTNSIRAIKARRAIVELLLSDHPKDCLLCEKNTKCELQKLA
CCCCCCCHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHH
ADMGIREMKYQGDVSMYPIDISSYSIVRDMDKCILCRRCITICNEVQTVGTLSAIGRGFE
HHCCHHHHEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
TVVAPAFSEAIKNTNCTFCGQCVSVCPTGALTEVNNTSKVWDALSQKDKIVIVQTAPAIR
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCHHHH
AALGEEFGLEPGTTVTGKMVAALRQLGFSKVFDTDFAADLTIMEEASEFIHRLEHGGTLP
HHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCH
MLTSCCPGWIKFFEHNFNDLMDIPSSCKSPQQMFGAIAKSYLAEKMKVDPKDIIVVSVMP
HHHHCCHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEHHHH
CLAKKYEAKREEMKRNGIPDVDIVISTRELAKMIVEAGIDFNSLQEEEFDNPLGESTGAS
HHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCHHHCCHHHCCCCCCCCCCCE
VIFGTTGGVMEAALRTAYEWVTKGTLKDVEFIEVRGEDGIREATVNIKDTEVKVAIASGL
EEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEECCEEEEEEECCC
GNARKLLNDIRNGKSKYHMIEIMACPSGCVDGGGQPYIYGDTNILKKRTEALYKEDSNKE
CHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCHH
IRKSHENPYIKKLYEEYLGKPYGEKAHELLHTKYRVR
HHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLVTLNINGKDLKVENGTTILDAAKLLNINIPTLCNFHLNDNKTENKPGSCRVCVVEVE
EEEEEEECCCEEEECCCCCCEEHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEC
GRKNLAPACCTPVGEGMIVKTNSIRAIKARRAIVELLLSDHPKDCLLCEKNTKCELQKLA
CCCCCCCHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHH
ADMGIREMKYQGDVSMYPIDISSYSIVRDMDKCILCRRCITICNEVQTVGTLSAIGRGFE
HHCCHHHHEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
TVVAPAFSEAIKNTNCTFCGQCVSVCPTGALTEVNNTSKVWDALSQKDKIVIVQTAPAIR
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCHHHH
AALGEEFGLEPGTTVTGKMVAALRQLGFSKVFDTDFAADLTIMEEASEFIHRLEHGGTLP
HHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCH
MLTSCCPGWIKFFEHNFNDLMDIPSSCKSPQQMFGAIAKSYLAEKMKVDPKDIIVVSVMP
HHHHCCHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEHHHH
CLAKKYEAKREEMKRNGIPDVDIVISTRELAKMIVEAGIDFNSLQEEEFDNPLGESTGAS
HHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCHHHCCHHHCCCCCCCCCCCE
VIFGTTGGVMEAALRTAYEWVTKGTLKDVEFIEVRGEDGIREATVNIKDTEVKVAIASGL
EEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEECCEEEEEEECCC
GNARKLLNDIRNGKSKYHMIEIMACPSGCVDGGGQPYIYGDTNILKKRTEALYKEDSNKE
CHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCHH
IRKSHENPYIKKLYEEYLGKPYGEKAHELLHTKYRVR
HHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]