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The map label for this gene is appC [H]

Identifier: 153935216

GI number: 153935216

Start: 1314601

End: 1315449

Strand: Reverse

Name: appC [H]

Synonym: CLC_1266

Alternate gene names: 153935216

Gene position: 1315449-1314601 (Counterclockwise)

Preceding gene: 153936678

Following gene: 153937045

Centisome position: 34.98

GC content: 28.5

Gene sequence:

>849_bases
TTGTTTTTAAATGAAAGACTTAAACTAAATTTAAAAATACAATTTAAAGAAAATAAATTAGGATATATATCTTTATCTAT
AATTTTAATATTAGTTCTTTTCTCAACCTTCTCTTTCTTGTCTCCTTATGACCCTAACAAAATAGATTTATCTAACAAAT
TAGCTAATCCTAGTTTAAAACATTTATTTGGTACTGATGAAATGGGAAGAGATTATTTTACTCGATCTTTATACGGTGGA
AGAGCTTCTTTAATGGTAGGTTTTATATCTATGATTATATCCACAACTCTAGGAACTATTGTAGGAACCTTTAGTGGTTA
TATAGGTGGAAAAATAGATAATATAATAATGAGAACCATAGATATATTAATGTGTATCCCAACCTTTTTTCTTATACTTA
TAATTAATGCCTACTTAAAACCTGGTATAGAAAATATAATAATTATTATTGGATTATTCGGTTGGATGGACATAGCTAGA
ATAGTTAGAGCTCAAACTCTTTCGTTAAAAGAAAGAGAATATGTACTATGTTCAAAGGCTTTAGGTGCTCCTAACAATAG
AATTATTTTTAAACATATAATTCCAAATGTTATCCCCTCTGTAATGGTAGCCTCCACCATAAATATTGCATCTGCTATTC
TTACAGAGTCATCCCTTAGTTTTCTAGGCTTAGGAGTTAGAGCACCTAATTCATCTTGGGGTAGTATGCTACAAAATGCT
CAAGGTTTTATTTCATCATCACCCTACTTAGCTATATTTCCTGGACTTTTTATACTTTTTACAGTTTTAAACTTTAATAT
ATTAGGAGATATTTTTGCCACTGCATTTGATTCTAAAGCTAATAAATAA

Upstream 100 bases:

>100_bases
CTATGTTAACTTCTGTTTTACTTATAATAGGTAACCTTTTAGCAGACATATGTTATAGCTTAATAGATCCTAGAATTAAA
GAGTTAGGTAGGTGATAAAT

Downstream 100 bases:

>100_bases
TGCTCCTTTAAAAATAAACCATTATATACGATAAAAGTACTGTATATATTTAATGGTTTATTTTCATTTATATTAACTAT
ACAGTAAATTGTTGACAAAC

Product: putative oligopeptide ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MFLNERLKLNLKIQFKENKLGYISLSIILILVLFSTFSFLSPYDPNKIDLSNKLANPSLKHLFGTDEMGRDYFTRSLYGG
RASLMVGFISMIISTTLGTIVGTFSGYIGGKIDNIIMRTIDILMCIPTFFLILIINAYLKPGIENIIIIIGLFGWMDIAR
IVRAQTLSLKEREYVLCSKALGAPNNRIIFKHIIPNVIPSVMVASTINIASAILTESSLSFLGLGVRAPNSSWGSMLQNA
QGFISSSPYLAIFPGLFILFTVLNFNILGDIFATAFDSKANK

Sequences:

>Translated_282_residues
MFLNERLKLNLKIQFKENKLGYISLSIILILVLFSTFSFLSPYDPNKIDLSNKLANPSLKHLFGTDEMGRDYFTRSLYGG
RASLMVGFISMIISTTLGTIVGTFSGYIGGKIDNIIMRTIDILMCIPTFFLILIINAYLKPGIENIIIIIGLFGWMDIAR
IVRAQTLSLKEREYVLCSKALGAPNNRIIFKHIIPNVIPSVMVASTINIASAILTESSLSFLGLGVRAPNSSWGSMLQNA
QGFISSSPYLAIFPGLFILFTVLNFNILGDIFATAFDSKANK
>Mature_282_residues
MFLNERLKLNLKIQFKENKLGYISLSIILILVLFSTFSFLSPYDPNKIDLSNKLANPSLKHLFGTDEMGRDYFTRSLYGG
RASLMVGFISMIISTTLGTIVGTFSGYIGGKIDNIIMRTIDILMCIPTFFLILIINAYLKPGIENIIIIIGLFGWMDIAR
IVRAQTLSLKEREYVLCSKALGAPNNRIIFKHIIPNVIPSVMVASTINIASAILTESSLSFLGLGVRAPNSSWGSMLQNA
QGFISSSPYLAIFPGLFILFTVLNFNILGDIFATAFDSKANK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=268, Percent_Identity=36.5671641791045, Blast_Score=198, Evalue=3e-52,
Organism=Escherichia coli, GI1787760, Length=268, Percent_Identity=36.5671641791045, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1789889, Length=242, Percent_Identity=38.4297520661157, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1787498, Length=273, Percent_Identity=37.3626373626374, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1789964, Length=275, Percent_Identity=36.3636363636364, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1788505, Length=223, Percent_Identity=33.1838565022422, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1787549, Length=238, Percent_Identity=28.5714285714286, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31185; Mature: 31185

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLNERLKLNLKIQFKENKLGYISLSIILILVLFSTFSFLSPYDPNKIDLSNKLANPSLK
CCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHH
HLFGTDEMGRDYFTRSLYGGRASLMVGFISMIISTTLGTIVGTFSGYIGGKIDNIIMRTI
HHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DILMCIPTFFLILIINAYLKPGIENIIIIIGLFGWMDIARIVRAQTLSLKEREYVLCSKA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGAPNNRIIFKHIIPNVIPSVMVASTINIASAILTESSLSFLGLGVRAPNSSWGSMLQNA
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEEECCCCHHHHHHHHH
QGFISSSPYLAIFPGLFILFTVLNFNILGDIFATAFDSKANK
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFLNERLKLNLKIQFKENKLGYISLSIILILVLFSTFSFLSPYDPNKIDLSNKLANPSLK
CCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHH
HLFGTDEMGRDYFTRSLYGGRASLMVGFISMIISTTLGTIVGTFSGYIGGKIDNIIMRTI
HHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DILMCIPTFFLILIINAYLKPGIENIIIIIGLFGWMDIARIVRAQTLSLKEREYVLCSKA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGAPNNRIIFKHIIPNVIPSVMVASTINIASAILTESSLSFLGLGVRAPNSSWGSMLQNA
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEEECCCCHHHHHHHHH
QGFISSSPYLAIFPGLFILFTVLNFNILGDIFATAFDSKANK
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]