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The map label for this gene is glcK [H]

Identifier: 153935077

GI number: 153935077

Start: 1706875

End: 1707822

Strand: Direct

Name: glcK [H]

Synonym: CLC_1631

Alternate gene names: 153935077

Gene position: 1706875-1707822 (Clockwise)

Preceding gene: 153935634

Following gene: 153936226

Centisome position: 45.39

GC content: 31.54

Gene sequence:

>948_bases
ATGAATAAAAAATATGTAGTGGGTGTTGATTTAGGGGGAACAAAGATTTATACAGCACTTGTGGATTTAGATGGAAATAT
AATAAAAGAAAAAAATGTTAAAACTGAAGCAAGCAAAGGAGAACTTGATGTATTATATAAAATAATAAATACTATTGATA
ATGTTATAGAAGGAGTAAACTTAGAGGAAATAAAGGCTATAGGAATAGGTTCACCAGGACCTTTAGATGCTAAAGAAGGT
ATAATAATTTCATCTTCAAATCTACCCTTTGAAAATTTTAGCTTAGTTCAACCTATAAAGGATAAATATAATATTCCAAC
ATACCTAGACAATGATGCTAATGTAGCTACTTTAGCTGAATTTATGTTTGGTAAAGGAAAAGGTACCCAGAACATGATAT
ACGTAACAGCAAGTACAGGCATTGGAGCAGGAGCTATAATAAATAGCAGAATATATAGAGGAAATACAGGAAATGCTTTA
GAAATAGGTCATACAACTGTTATGAAGGATGGACCGAACTGTGGTTGTGGTAATAAGGGTTGCGCAGAAAGTTTAGGTTC
TGGTACTGCCATTATGAAAAAGGCAAAAGAAGTTTGTAAAAATAATGGAGAGACATCTTTAAAAAAATATGATAATCTAA
CTGCAAAGGAAGTTTTTGAAGAAGCTAAAAAAGGAGATAAGCTTTCAAAAGAAGTACTAGAATTTTGCTTATCCTATTTA
GGTATAACTGTAGCCAATATAATAAATACTTTTGATCCAGAAATGGTTGTTATAGGCGGAGGAGTTATAAATGGTGGAGA
AATTGTTTGTGATATAATAAATAGAGAAGTGAAAAATAGATGCTGGAAAGCTATTAGAGATAATTGTAAAATAACAAAAG
CAAAGCTTGCAGGAAAAGCAGGGGTTCTAGGAGCTGCAGCCTTAGCTATAACTGAAAGTAAAAATTAA

Upstream 100 bases:

>100_bases
TTATTAGTATTATTAATAAATAAAAACTTATTAAATAATAGATTTTATAAGGATTAATATGAAGTTTTAAATTTATATTA
GTAATTATTGAGGTGATAAA

Downstream 100 bases:

>100_bases
TGTTCTAAATCTAGTATATATATTTAGTTGGCTTATATTCTTATAAAGTTATAGTTATTGCCAAGAATAAGAAATGAGTT
TATAACTATAAGTATTAGTT

Product: putative glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MNKKYVVGVDLGGTKIYTALVDLDGNIIKEKNVKTEASKGELDVLYKIINTIDNVIEGVNLEEIKAIGIGSPGPLDAKEG
IIISSSNLPFENFSLVQPIKDKYNIPTYLDNDANVATLAEFMFGKGKGTQNMIYVTASTGIGAGAIINSRIYRGNTGNAL
EIGHTTVMKDGPNCGCGNKGCAESLGSGTAIMKKAKEVCKNNGETSLKKYDNLTAKEVFEEAKKGDKLSKEVLEFCLSYL
GITVANIINTFDPEMVVIGGGVINGGEIVCDIINREVKNRCWKAIRDNCKITKAKLAGKAGVLGAAALAITESKN

Sequences:

>Translated_315_residues
MNKKYVVGVDLGGTKIYTALVDLDGNIIKEKNVKTEASKGELDVLYKIINTIDNVIEGVNLEEIKAIGIGSPGPLDAKEG
IIISSSNLPFENFSLVQPIKDKYNIPTYLDNDANVATLAEFMFGKGKGTQNMIYVTASTGIGAGAIINSRIYRGNTGNAL
EIGHTTVMKDGPNCGCGNKGCAESLGSGTAIMKKAKEVCKNNGETSLKKYDNLTAKEVFEEAKKGDKLSKEVLEFCLSYL
GITVANIINTFDPEMVVIGGGVINGGEIVCDIINREVKNRCWKAIRDNCKITKAKLAGKAGVLGAAALAITESKN
>Mature_315_residues
MNKKYVVGVDLGGTKIYTALVDLDGNIIKEKNVKTEASKGELDVLYKIINTIDNVIEGVNLEEIKAIGIGSPGPLDAKEG
IIISSSNLPFENFSLVQPIKDKYNIPTYLDNDANVATLAEFMFGKGKGTQNMIYVTASTGIGAGAIINSRIYRGNTGNAL
EIGHTTVMKDGPNCGCGNKGCAESLGSGTAIMKKAKEVCKNNGETSLKKYDNLTAKEVFEEAKKGDKLSKEVLEFCLSYL
GITVANIINTFDPEMVVIGGGVINGGEIVCDIINREVKNRCWKAIRDNCKITKAKLAGKAGVLGAAALAITESKN

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=281, Percent_Identity=32.0284697508897, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI298566325, Length=281, Percent_Identity=32.0284697508897, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI4885285, Length=281, Percent_Identity=32.0284697508897, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI190014632, Length=281, Percent_Identity=32.0284697508897, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI298566312, Length=134, Percent_Identity=29.8507462686567, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1786891, Length=307, Percent_Identity=30.9446254071661, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1787878, Length=298, Percent_Identity=26.8456375838926, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87082230, Length=260, Percent_Identity=31.9230769230769, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787363, Length=317, Percent_Identity=25.8675078864353, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87081733, Length=321, Percent_Identity=24.6105919003115, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790522, Length=271, Percent_Identity=25.4612546125461, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI87082127, Length=178, Percent_Identity=25.8426966292135, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33551; Mature: 33551

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKYVVGVDLGGTKIYTALVDLDGNIIKEKNVKTEASKGELDVLYKIINTIDNVIEGVN
CCCCEEEEEECCCCEEEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
LEEIKAIGIGSPGPLDAKEGIIISSSNLPFENFSLVQPIKDKYNIPTYLDNDANVATLAE
HHHEEEEECCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCCEECCCCCHHHHHH
FMFGKGKGTQNMIYVTASTGIGAGAIINSRIYRGNTGNALEIGHTTVMKDGPNCGCGNKG
HHHCCCCCCCEEEEEEECCCCCCCCEECCEEEECCCCCEEEECCEEEEECCCCCCCCCCH
CAESLGSGTAIMKKAKEVCKNNGETSLKKYDNLTAKEVFEEAKKGDKLSKEVLEFCLSYL
HHHHHCCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
GITVANIINTFDPEMVVIGGGVINGGEIVCDIINREVKNRCWKAIRDNCKITKAKLAGKA
HHHHHHHHHCCCCCEEEEECCEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCC
GVLGAAALAITESKN
CHHHHEEEEEECCCC
>Mature Secondary Structure
MNKKYVVGVDLGGTKIYTALVDLDGNIIKEKNVKTEASKGELDVLYKIINTIDNVIEGVN
CCCCEEEEEECCCCEEEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
LEEIKAIGIGSPGPLDAKEGIIISSSNLPFENFSLVQPIKDKYNIPTYLDNDANVATLAE
HHHEEEEECCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCCEECCCCCHHHHHH
FMFGKGKGTQNMIYVTASTGIGAGAIINSRIYRGNTGNALEIGHTTVMKDGPNCGCGNKG
HHHCCCCCCCEEEEEEECCCCCCCCEECCEEEECCCCCEEEECCEEEEECCCCCCCCCCH
CAESLGSGTAIMKKAKEVCKNNGETSLKKYDNLTAKEVFEEAKKGDKLSKEVLEFCLSYL
HHHHHCCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
GITVANIINTFDPEMVVIGGGVINGGEIVCDIINREVKNRCWKAIRDNCKITKAKLAGKA
HHHHHHHHHCCCCCEEEEECCEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCC
GVLGAAALAITESKN
CHHHHEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]