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The map label for this gene is metA [H]

Identifier: 153934712

GI number: 153934712

Start: 1929759

End: 1930655

Strand: Reverse

Name: metA [H]

Synonym: CLC_1818

Alternate gene names: 153934712

Gene position: 1930655-1929759 (Counterclockwise)

Preceding gene: 153935671

Following gene: 153934727

Centisome position: 51.34

GC content: 24.3

Gene sequence:

>897_bases
ATGGCTTTAATCATAGATAAAAACCTTCCAGCTTACCAAATATTAAAATCTGAAAATATAAATATAATGGATAAATTAAA
TTATAACAAAAATACAAATAAATTAAAACTTATAATATTAAACTTGATGCCTAAAAAAATAGAGGCGGAAACACAAATAC
TAAGAGTCTTATGTAAAAGTTTTATAGATTTAGAGATTACTTTTTTAAAAACTGAAAGTTATAAGAGTAAAAATACAAGC
AATGATCATTTAAATAAATTTTATAAGACTTTTAGTGAAATAAAAAATCATAATTTTCATGGAATGATTATAACCGGTGC
TCCAGTAGAACTTATGGATTTTGAAAGAGTAGATTATTGGGAAGAACTTAAAAATATAATGGATTATTGTAATAAAAAAG
TAAAATCTACTATATTCATATGTTGGGCAGCTCAAGCAGCCTTATACTACTATTATGATATAAATAAGTATTCATTAAAT
AAAAAGCTTTTTGGTGTGTTTCCTCACAAAATAAGTAAAGAAAATTCTTTACTTACTAAAGGTTTTGATGATGAATTTTA
TGTACCCCATTCCAGGTATACTTATACAAGAAAAGAAGATATAAAAAGATGCAAAGATATAGAGATAATTTCCGAATCAG
AAGAGGCAGGATTATATTTAATGCAAAGCAATAATTTTAAAAAAATATTTATATCAGGACACTGTGAATATGACAGGTAT
ACATTATATGAAGAATATATTAGAGATATAAATAAGAATAAGCATATAGACATTCCTAAAAACTATTTTAAAGAAAATAA
TTTAAACAAAAAACCTATAATGAAATGGCGTTGTCATGGAGAAACCTTGTTTTTAAATTGGATACAGTTGCTAGAAAAGT
TATCAAGTGATTCTTAG

Upstream 100 bases:

>100_bases
ATTTAAAAGATAAGCTGGATAGTATACCTAATATTAAAAAATTAAAGGCTACTATAATTTTATTCCATAGCTAAGGGCTA
GTTAGCAAAGGAAATAAAAT

Downstream 100 bases:

>100_bases
GTACAAGTAAAGTTTGCTTAGAATAATTACTGTTGGCATAGACAGGATAAAAATTGATATGTATTCATAATATAATAATT
AAATTTACAACAAAAAATGA

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MALIIDKNLPAYQILKSENINIMDKLNYNKNTNKLKLIILNLMPKKIEAETQILRVLCKSFIDLEITFLKTESYKSKNTS
NDHLNKFYKTFSEIKNHNFHGMIITGAPVELMDFERVDYWEELKNIMDYCNKKVKSTIFICWAAQAALYYYYDINKYSLN
KKLFGVFPHKISKENSLLTKGFDDEFYVPHSRYTYTRKEDIKRCKDIEIISESEEAGLYLMQSNNFKKIFISGHCEYDRY
TLYEEYIRDINKNKHIDIPKNYFKENNLNKKPIMKWRCHGETLFLNWIQLLEKLSSDS

Sequences:

>Translated_298_residues
MALIIDKNLPAYQILKSENINIMDKLNYNKNTNKLKLIILNLMPKKIEAETQILRVLCKSFIDLEITFLKTESYKSKNTS
NDHLNKFYKTFSEIKNHNFHGMIITGAPVELMDFERVDYWEELKNIMDYCNKKVKSTIFICWAAQAALYYYYDINKYSLN
KKLFGVFPHKISKENSLLTKGFDDEFYVPHSRYTYTRKEDIKRCKDIEIISESEEAGLYLMQSNNFKKIFISGHCEYDRY
TLYEEYIRDINKNKHIDIPKNYFKENNLNKKPIMKWRCHGETLFLNWIQLLEKLSSDS
>Mature_297_residues
ALIIDKNLPAYQILKSENINIMDKLNYNKNTNKLKLIILNLMPKKIEAETQILRVLCKSFIDLEITFLKTESYKSKNTSN
DHLNKFYKTFSEIKNHNFHGMIITGAPVELMDFERVDYWEELKNIMDYCNKKVKSTIFICWAAQAALYYYYDINKYSLNK
KLFGVFPHKISKENSLLTKGFDDEFYVPHSRYTYTRKEDIKRCKDIEIISESEEAGLYLMQSNNFKKIFISGHCEYDRYT
LYEEYIRDINKNKHIDIPKNYFKENNLNKKPIMKWRCHGETLFLNWIQLLEKLSSDS

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=289, Percent_Identity=42.2145328719723, Blast_Score=260, Evalue=7e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 35638; Mature: 35506

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALIIDKNLPAYQILKSENINIMDKLNYNKNTNKLKLIILNLMPKKIEAETQILRVLCKS
CEEEEECCCCHHHHHHCCCCCEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHH
FIDLEITFLKTESYKSKNTSNDHLNKFYKTFSEIKNHNFHGMIITGAPVELMDFERVDYW
HCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCCHHCHHH
EELKNIMDYCNKKVKSTIFICWAAQAALYYYYDINKYSLNKKLFGVFPHKISKENSLLTK
HHHHHHHHHHCHHHHHEEEEEEECCEEEEEEEECCEEECCCCEEEECCCCCCCCCCEEEC
GFDDEFYVPHSRYTYTRKEDIKRCKDIEIISESEEAGLYLMQSNNFKKIFISGHCEYDRY
CCCCCEECCCCCEEECCHHHHHHHCCCEEECCCCCCCEEEEECCCEEEEEEECCCCCCHH
TLYEEYIRDINKNKHIDIPKNYFKENNLNKKPIMKWRCHGETLFLNWIQLLEKLSSDS
HHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALIIDKNLPAYQILKSENINIMDKLNYNKNTNKLKLIILNLMPKKIEAETQILRVLCKS
EEEEECCCCHHHHHHCCCCCEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHH
FIDLEITFLKTESYKSKNTSNDHLNKFYKTFSEIKNHNFHGMIITGAPVELMDFERVDYW
HCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCCHHCHHH
EELKNIMDYCNKKVKSTIFICWAAQAALYYYYDINKYSLNKKLFGVFPHKISKENSLLTK
HHHHHHHHHHCHHHHHEEEEEEECCEEEEEEEECCEEECCCCEEEECCCCCCCCCCEEEC
GFDDEFYVPHSRYTYTRKEDIKRCKDIEIISESEEAGLYLMQSNNFKKIFISGHCEYDRY
CCCCCEECCCCCEEECCHHHHHHHCCCEEECCCCCCCEEEEECCCEEEEEEECCCCCCHH
TLYEEYIRDINKNKHIDIPKNYFKENNLNKKPIMKWRCHGETLFLNWIQLLEKLSSDS
HHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA