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The map label for this gene is serS [H]

Identifier: 153933443

GI number: 153933443

Start: 2648030

End: 2649223

Strand: Reverse

Name: serS [H]

Synonym: CLB_2532

Alternate gene names: 153933443

Gene position: 2649223-2648030 (Counterclockwise)

Preceding gene: 153932871

Following gene: 153933595

Centisome position: 68.57

GC content: 25.04

Gene sequence:

>1194_bases
ATGTTTAAGTATTCTATAAAAAATTTAAGAGAAGAAGATAAGAATTTTTTTAAAGATATGATACCGTACTTATCACAGTA
CATTATAAAATATGAGATGAAAGAAGGGGACGTATTTATTTATTGTGATGTAGATAATGAAAATCAGATACGCAATTGTC
TAGATAATCTAATAAATATGATTAATAAAAATATCTTGTCGGAAAAAACTGAAAAAATTAAAACTATAGAAGACTATACT
AGTTATACAACTATTAATCATTCTAATATTTACAATAATCTTGTAAGTAGAGGTGATGTGAGAGAATTAGCAAAAGGATC
TTTTGCTTATAGTGGATTGTTTTTAGATATATATGAATATTTTGAAAGAAAGATTGATGAGTTTGCTTGTTCTAAATTCA
AAAATATAAGAAAAATTGTGTATCCAGATTTGCATTCGATTCAAGATTATATAAAAGGTCGTTATTTTGAAAATTTTCCT
CATTATATGATGTTTCAGACGACATTAAAGAATGATATGAGTGTTTATGAAAAGTTTTCTAAATGTAAATTTGAGTATAA
AAGTATTTTAGATGAAATAAAGACTCCTCAAAATGTTCTTCGGCATGCGGCTTGTGTACCTGTATATTCTTTATTGGAAA
ATGAGATGCTAGATGCAGAAGAAGTGCAAAGTTTTATTGTATCAGGAAAATGCTTTAGAAACGAAGAAGATAATATATTT
GAATTAAGTAGATTGAATGAATTTTATATGAAAGAATTTGTTTTTGTAGGTGATGAAAATGCAGTTAATAAAATGATAGA
AATTTCTAAAGAATTGATTAAATTTTGGGTTGATATATTTAAATTGAATAGTAAATATGAAACTGCAAATGACTCATTTT
TCGCTAATAATTATAAGAAAATGAAATTTTTTCAAATTATAGGTGAATCAAAACAAGAATTTAAAGCCTTTATTCCTGGG
AATAAAAATTACATTGCAGCAAGCTCAATTAATTATCATAGGACTCATTTTTCTAAGGTATATAATATTATAGGTGAAAA
AGGTAATTATTGTTATAGTGCATGTTTTGCATTTGGAATTGAGAGATTAGCTTATGCATTACTATCACAAAAAGGATTGA
ACATTGATAAATGGGATTTTGAAACTATTAAAGAGATAGAAAAATACAGTAAATTAAGGAGTAATGAAAAATGA

Upstream 100 bases:

>100_bases
TATCTATAAAAGAATTTATATTTTTGAGCCTGAAATTAATTATAAAGGAGGATTGGCTTTACAATGTATTAAAACTAATT
GAAGGATGGAGAGGGTTTAA

Downstream 100 bases:

>100_bases
ATTACAATATAGAGGTTAGACGTTGTAAAAGTTGTATTTTACCTGAAGTCCCAGGACATGTAGAGTTAGATAGTAATGGT
ATATGTAATATTTGCAATGG

Product: putative seryl-tRNA synthetase

Products: NA

Alternate protein names: Serine--tRNA ligase; SerRS; Seryl-tRNA(Ser/Sec) synthetase [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MFKYSIKNLREEDKNFFKDMIPYLSQYIIKYEMKEGDVFIYCDVDNENQIRNCLDNLINMINKNILSEKTEKIKTIEDYT
SYTTINHSNIYNNLVSRGDVRELAKGSFAYSGLFLDIYEYFERKIDEFACSKFKNIRKIVYPDLHSIQDYIKGRYFENFP
HYMMFQTTLKNDMSVYEKFSKCKFEYKSILDEIKTPQNVLRHAACVPVYSLLENEMLDAEEVQSFIVSGKCFRNEEDNIF
ELSRLNEFYMKEFVFVGDENAVNKMIEISKELIKFWVDIFKLNSKYETANDSFFANNYKKMKFFQIIGESKQEFKAFIPG
NKNYIAASSINYHRTHFSKVYNIIGEKGNYCYSACFAFGIERLAYALLSQKGLNIDKWDFETIKEIEKYSKLRSNEK

Sequences:

>Translated_397_residues
MFKYSIKNLREEDKNFFKDMIPYLSQYIIKYEMKEGDVFIYCDVDNENQIRNCLDNLINMINKNILSEKTEKIKTIEDYT
SYTTINHSNIYNNLVSRGDVRELAKGSFAYSGLFLDIYEYFERKIDEFACSKFKNIRKIVYPDLHSIQDYIKGRYFENFP
HYMMFQTTLKNDMSVYEKFSKCKFEYKSILDEIKTPQNVLRHAACVPVYSLLENEMLDAEEVQSFIVSGKCFRNEEDNIF
ELSRLNEFYMKEFVFVGDENAVNKMIEISKELIKFWVDIFKLNSKYETANDSFFANNYKKMKFFQIIGESKQEFKAFIPG
NKNYIAASSINYHRTHFSKVYNIIGEKGNYCYSACFAFGIERLAYALLSQKGLNIDKWDFETIKEIEKYSKLRSNEK
>Mature_397_residues
MFKYSIKNLREEDKNFFKDMIPYLSQYIIKYEMKEGDVFIYCDVDNENQIRNCLDNLINMINKNILSEKTEKIKTIEDYT
SYTTINHSNIYNNLVSRGDVRELAKGSFAYSGLFLDIYEYFERKIDEFACSKFKNIRKIVYPDLHSIQDYIKGRYFENFP
HYMMFQTTLKNDMSVYEKFSKCKFEYKSILDEIKTPQNVLRHAACVPVYSLLENEMLDAEEVQSFIVSGKCFRNEEDNIF
ELSRLNEFYMKEFVFVGDENAVNKMIEISKELIKFWVDIFKLNSKYETANDSFFANNYKKMKFFQIIGESKQEFKAFIPG
NKNYIAASSINYHRTHFSKVYNIIGEKGNYCYSACFAFGIERLAYALLSQKGLNIDKWDFETIKEIEKYSKLRSNEK

Specific function: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) [H]

COG id: COG0172

COG function: function code J; Seryl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR002317
- InterPro:   IPR004503 [H]

Pfam domain/function: PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.11 [H]

Molecular weight: Translated: 47256; Mature: 47256

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKYSIKNLREEDKNFFKDMIPYLSQYIIKYEMKEGDVFIYCDVDNENQIRNCLDNLINM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHHH
INKNILSEKTEKIKTIEDYTSYTTINHSNIYNNLVSRGDVRELAKGSFAYSGLFLDIYEY
HHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHH
FERKIDEFACSKFKNIRKIVYPDLHSIQDYIKGRYFENFPHYMMFQTTLKNDMSVYEKFS
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHH
KCKFEYKSILDEIKTPQNVLRHAACVPVYSLLENEMLDAEEVQSFIVSGKCFRNEEDNIF
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHCCCCCCCHH
ELSRLNEFYMKEFVFVGDENAVNKMIEISKELIKFWVDIFKLNSKYETANDSFFANNYKK
HHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHH
MKFFQIIGESKQEFKAFIPGNKNYIAASSINYHRTHFSKVYNIIGEKGNYCYSACFAFGI
HHHHHHHCCCHHHHHEECCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ERLAYALLSQKGLNIDKWDFETIKEIEKYSKLRSNEK
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFKYSIKNLREEDKNFFKDMIPYLSQYIIKYEMKEGDVFIYCDVDNENQIRNCLDNLINM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHHH
INKNILSEKTEKIKTIEDYTSYTTINHSNIYNNLVSRGDVRELAKGSFAYSGLFLDIYEY
HHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHH
FERKIDEFACSKFKNIRKIVYPDLHSIQDYIKGRYFENFPHYMMFQTTLKNDMSVYEKFS
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHH
KCKFEYKSILDEIKTPQNVLRHAACVPVYSLLENEMLDAEEVQSFIVSGKCFRNEEDNIF
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHCCCCCCCHH
ELSRLNEFYMKEFVFVGDENAVNKMIEISKELIKFWVDIFKLNSKYETANDSFFANNYKK
HHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHH
MKFFQIIGESKQEFKAFIPGNKNYIAASSINYHRTHFSKVYNIIGEKGNYCYSACFAFGI
HHHHHHHCCCHHHHHEECCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ERLAYALLSQKGLNIDKWDFETIKEIEKYSKLRSNEK
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]