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The map label for this gene is walR [H]

Identifier: 153932630

GI number: 153932630

Start: 2539599

End: 2540297

Strand: Reverse

Name: walR [H]

Synonym: CLB_2404

Alternate gene names: 153932630

Gene position: 2540297-2539599 (Counterclockwise)

Preceding gene: 153932022

Following gene: 153933173

Centisome position: 65.75

GC content: 29.61

Gene sequence:

>699_bases
ATGGCTATGGAAAAAATACTTATAGTAGACGATGAAGAACATATATGTGAATTAATAAAATTTAATTTGGAAAATAATAG
TTATAACTGTATTTGTGCTTTGAATGGGATAGAGGCATTAAATATAGCTAAAGAAGAAAAACCAGATTTAATACTTTTAG
ATCTAATGTTACCGGGAATGGATGGATATGAGGTTTGTAAGGAAATAAGGAAAGATAATAATATAGCTACTACCCCTATA
ATAATGATTACAGCTAAAGGAGAGGAATTGGATAAAGTTTTGGGCTTAGAACTAGGAGCGGATGATTATATAACCAAACC
TTTTTCAGTTAGAGAAATGGTAGCTAGAGTAAAAGCGGTACTTAGAAGAAGAACAACCATAAATATAGAATCTAAATCCT
ATATTTTAGGGAATATTGTTGTGGATTTTGAAAAACATTCTCTTACAAAGGCAGGAGAAAAAATAGAACTTACTCTAAAA
GAGTTTGAACTTTTAGAGGTGTTAATAAAGAATAAAGGGAAGGTTATGACAAGAGATTTTTTGCTAGATAGAATATGGGG
ATATGAATACATTGGAGAAACTAGGACTGTAGATGTGCATATAAGGCATTTAAGAAAAAAAATAGAGGATGATGATAAAA
ATCCTAAGTTTATTGAAACTATAAGGGGAATAGGATATAGATTCAATAGTGAATTTTAA

Upstream 100 bases:

>100_bases
ATGTGTAGTTCTGATCCTAAATTTTATTCCTATAGAAAAGAGGGGAATATAGGAAGACAATTTTCCTTTGTATATTTAAA
CAAACAGTAGGAGGGGTACC

Downstream 100 bases:

>100_bases
AAGGTGAAGTTATGAAAAAAAAATTAACATTATCAATACTTATAATTTTAATATTTACATTAACAATAGTATCATCACTT
TTCTTAATAACCATTAATAA

Product: putative phosphate regulon DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MAMEKILIVDDEEHICELIKFNLENNSYNCICALNGIEALNIAKEEKPDLILLDLMLPGMDGYEVCKEIRKDNNIATTPI
IMITAKGEELDKVLGLELGADDYITKPFSVREMVARVKAVLRRRTTINIESKSYILGNIVVDFEKHSLTKAGEKIELTLK
EFELLEVLIKNKGKVMTRDFLLDRIWGYEYIGETRTVDVHIRHLRKKIEDDDKNPKFIETIRGIGYRFNSEF

Sequences:

>Translated_232_residues
MAMEKILIVDDEEHICELIKFNLENNSYNCICALNGIEALNIAKEEKPDLILLDLMLPGMDGYEVCKEIRKDNNIATTPI
IMITAKGEELDKVLGLELGADDYITKPFSVREMVARVKAVLRRRTTINIESKSYILGNIVVDFEKHSLTKAGEKIELTLK
EFELLEVLIKNKGKVMTRDFLLDRIWGYEYIGETRTVDVHIRHLRKKIEDDDKNPKFIETIRGIGYRFNSEF
>Mature_231_residues
AMEKILIVDDEEHICELIKFNLENNSYNCICALNGIEALNIAKEEKPDLILLDLMLPGMDGYEVCKEIRKDNNIATTPII
MITAKGEELDKVLGLELGADDYITKPFSVREMVARVKAVLRRRTTINIESKSYILGNIVVDFEKHSLTKAGEKIELTLKE
FELLEVLIKNKGKVMTRDFLLDRIWGYEYIGETRTVDVHIRHLRKKIEDDDKNPKFIETIRGIGYRFNSEF

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=42.5438596491228, Blast_Score=190, Evalue=5e-50,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=41.4096916299559, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=37.117903930131, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=38.2882882882883, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=36.283185840708, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=38.2222222222222, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=34.070796460177, Blast_Score=150, Evalue=5e-38,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=38.695652173913, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=36.5957446808511, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=35.1351351351351, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=34.2222222222222, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=33.0508474576271, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=32.8828828828829, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=32.0175438596491, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788550, Length=121, Percent_Identity=35.5371900826446, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790299, Length=113, Percent_Identity=32.7433628318584, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788191, Length=107, Percent_Identity=29.9065420560748, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790437, Length=128, Percent_Identity=31.25, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI145693157, Length=105, Percent_Identity=34.2857142857143, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26783; Mature: 26651

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMEKILIVDDEEHICELIKFNLENNSYNCICALNGIEALNIAKEEKPDLILLDLMLPGM
CCCCEEEEEECHHHHHHHHHEECCCCCEEEEEEECCCCEECCCCCCCCCEEEEEEECCCC
DGYEVCKEIRKDNNIATTPIIMITAKGEELDKVLGLELGADDYITKPFSVREMVARVKAV
CHHHHHHHHHHCCCEEECEEEEEEECCHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHH
LRRRTTINIESKSYILGNIVVDFEKHSLTKAGEKIELTLKEFELLEVLIKNKGKVMTRDF
HHHCCEEEECCCCEEEEEEEEEECHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCEEHHHH
LLDRIWGYEYIGETRTVDVHIRHLRKKIEDDDKNPKFIETIRGIGYRFNSEF
HHHHHCCHHHCCCCEEEEHHHHHHHHHHCCCCCCCHHHHHHHHCCEEECCCC
>Mature Secondary Structure 
AMEKILIVDDEEHICELIKFNLENNSYNCICALNGIEALNIAKEEKPDLILLDLMLPGM
CCCEEEEEECHHHHHHHHHEECCCCCEEEEEEECCCCEECCCCCCCCCEEEEEEECCCC
DGYEVCKEIRKDNNIATTPIIMITAKGEELDKVLGLELGADDYITKPFSVREMVARVKAV
CHHHHHHHHHHCCCEEECEEEEEEECCHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHH
LRRRTTINIESKSYILGNIVVDFEKHSLTKAGEKIELTLKEFELLEVLIKNKGKVMTRDF
HHHCCEEEECCCCEEEEEEEEEECHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCEEHHHH
LLDRIWGYEYIGETRTVDVHIRHLRKKIEDDDKNPKFIETIRGIGYRFNSEF
HHHHHCCHHHCCCCEEEEHHHHHHHHHHCCCCCCCHHHHHHHHCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA