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The map label for this gene is hisK [H]

Identifier: 153932622

GI number: 153932622

Start: 2622088

End: 2622855

Strand: Reverse

Name: hisK [H]

Synonym: CLB_2512

Alternate gene names: 153932622

Gene position: 2622855-2622088 (Counterclockwise)

Preceding gene: 153933335

Following gene: 153933551

Centisome position: 67.89

GC content: 25.65

Gene sequence:

>768_bases
ATGTTTGATACACATTTACATACAGAGTTTTCTACAGATTCTAAAATGACCATAGGTGAAGCTATAAAGGCTTCTAAAGA
TAATGATTTAGGTATAATAGTAACAGAACATATGGATCTAGGATTAAAGGATGAAAATAAATTTTGTTTTCATGTACCTT
CTTATTTTGAAAAGTATAATGAATATAGAAACAATAAATTACTTTTAGGTATAGAATTAGGAATGGAAAAAGATCTTATA
GAAGAAGGAAAAGAAGTAATTAATAGTGGGGAATTTGATTATGTAATAGGTTCCATTCATTTAATAGATAAAGTTGATTT
ATATTTAGATGAATTTTATAAGGATAAAAGTAAAGAGGAAGCTTTTCATATTTATTTTAGAAATATGAGACATAATTTAG
AAAAATATGATTTTGTAGATAGTCTAGGGCATATAGATTATATTTCAAGATATGCCAATTATGAAGACCCTGACATAAAT
TATGATATTTTTAAAGAGGATATAGATGAAGTTTTAAGGGTTATAGTAGAAAAGGAAAAATCTATGGAAATCAATACAAG
GAGATTAAATCATAAAAGGGCTGCGGAAAATTTAGTTAAAATATATAAAAGATTTTATGAACTAGGAGGAAGAACAGTTA
CATTAGGTTCTGATTCTCATAATGCTAAAGATATAGGAAATAGATTGAGCTTTGGAAAAGAAATTGCGGATTATTGCAAT
TTAAAGGTTGTATATTATAAAAATAGAAAGCCTGAATATGATAAATAG

Upstream 100 bases:

>100_bases
AAACTCCTAAGAATTCTGTTAATAAGCTTCAGAGGGAGTAAAAACTCCCTCTGAAGCTTAGAAATCTGTTTATATTGAAT
ATTATAAAAGAGGTGGGAAA

Downstream 100 bases:

>100_bases
GATTGATTAGAGAGTATGCATCTTAAAATTAAATCTATTTTCAGATTACATTTTTCAAAGACTAGAATTTATCCGATGAC
TACCCGCTCTAATACTCCCA

Product: histidinol-phosphatase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MFDTHLHTEFSTDSKMTIGEAIKASKDNDLGIIVTEHMDLGLKDENKFCFHVPSYFEKYNEYRNNKLLLGIELGMEKDLI
EEGKEVINSGEFDYVIGSIHLIDKVDLYLDEFYKDKSKEEAFHIYFRNMRHNLEKYDFVDSLGHIDYISRYANYEDPDIN
YDIFKEDIDEVLRVIVEKEKSMEINTRRLNHKRAAENLVKIYKRFYELGGRTVTLGSDSHNAKDIGNRLSFGKEIADYCN
LKVVYYKNRKPEYDK

Sequences:

>Translated_255_residues
MFDTHLHTEFSTDSKMTIGEAIKASKDNDLGIIVTEHMDLGLKDENKFCFHVPSYFEKYNEYRNNKLLLGIELGMEKDLI
EEGKEVINSGEFDYVIGSIHLIDKVDLYLDEFYKDKSKEEAFHIYFRNMRHNLEKYDFVDSLGHIDYISRYANYEDPDIN
YDIFKEDIDEVLRVIVEKEKSMEINTRRLNHKRAAENLVKIYKRFYELGGRTVTLGSDSHNAKDIGNRLSFGKEIADYCN
LKVVYYKNRKPEYDK
>Mature_255_residues
MFDTHLHTEFSTDSKMTIGEAIKASKDNDLGIIVTEHMDLGLKDENKFCFHVPSYFEKYNEYRNNKLLLGIELGMEKDLI
EEGKEVINSGEFDYVIGSIHLIDKVDLYLDEFYKDKSKEEAFHIYFRNMRHNLEKYDFVDSLGHIDYISRYANYEDPDIN
YDIFKEDIDEVLRVIVEKEKSMEINTRRLNHKRAAENLVKIYKRFYELGGRTVTLGSDSHNAKDIGNRLSFGKEIADYCN
LKVVYYKNRKPEYDK

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 30140; Mature: 30140

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDTHLHTEFSTDSKMTIGEAIKASKDNDLGIIVTEHMDLGLKDENKFCFHVPSYFEKYN
CCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEECHHHHHHHH
EYRNNKLLLGIELGMEKDLIEEGKEVINSGEFDYVIGSIHLIDKVDLYLDEFYKDKSKEE
HHCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCH
AFHIYFRNMRHNLEKYDFVDSLGHIDYISRYANYEDPDINYDIFKEDIDEVLRVIVEKEK
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
SMEINTRRLNHKRAAENLVKIYKRFYELGGRTVTLGSDSHNAKDIGNRLSFGKEIADYCN
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHC
LKVVYYKNRKPEYDK
EEEEEEECCCCCCCC
>Mature Secondary Structure
MFDTHLHTEFSTDSKMTIGEAIKASKDNDLGIIVTEHMDLGLKDENKFCFHVPSYFEKYN
CCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEECHHHHHHHH
EYRNNKLLLGIELGMEKDLIEEGKEVINSGEFDYVIGSIHLIDKVDLYLDEFYKDKSKEE
HHCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCH
AFHIYFRNMRHNLEKYDFVDSLGHIDYISRYANYEDPDINYDIFKEDIDEVLRVIVEKEK
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
SMEINTRRLNHKRAAENLVKIYKRFYELGGRTVTLGSDSHNAKDIGNRLSFGKEIADYCN
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHC
LKVVYYKNRKPEYDK
EEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]