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The map label for this gene is atoC [H]

Identifier: 153931019

GI number: 153931019

Start: 2496715

End: 2498469

Strand: Reverse

Name: atoC [H]

Synonym: CLB_2362

Alternate gene names: 153931019

Gene position: 2498469-2496715 (Counterclockwise)

Preceding gene: 153931211

Following gene: 153934307

Centisome position: 64.67

GC content: 28.09

Gene sequence:

>1755_bases
ATGAATAGTTCTATAGAATTAATTTACACTGTAAAAAATGTAATGAAGACAGATTTTATAAAAGTATTTAAAAATGAAGC
AATATCATCTGCCTTCAATAAAATGGCTAAACTTTATAAAGATGAAGTTCTTATAGTAGATGAAGATGATAATATTATAG
GTATATTTACTAAAAATGATTTATATAAATTGGAAAACCAGGGCAAAAAATTTAGTGATAACTTAGAAAATTATATAAAA
AGAGATGTAATAACAATTTCTGAAGAAAAGTCAATTATTTCTGCAAGAAATATAATGGTTAAAAATAAAATAGAAAGATT
ACCTATAGTACATAATAGAAAAATAATAGGGATAGTACATTTAGACGATTTAAATAATGAACTATACACAAATGTAGAAG
AATTATATGTTCTTCAGGATAGAATTTTGGAGAATATGCATGAAGCAGTATGTATAACAAATAACAAAGGTGTAGTAATA
TATTGGAATAAAAGTTCAGAAGACCTCTATGGTGTGAAGAGACAGGAGATAATAGGTAAATATTTAGGGGCTTTTTTCCC
AAATGCTTTAATATTAAAAGTTTTGAAAAATCCTAGAAAAATAACTAATGTAAACAATGAACCTTCTCCTGGAAAAACTG
TTATATTAAGTGCAGTACCTATATTTAATAGTAAAAACAAATTGATAGCAGTGGCTTCTACAGATAGAGATATAACAGAG
GTAATATCTTTATCTAAGGAACTTATGCAGGAAAAAAAGAAGGTGGAATTTTTTGAAAGTGCCTATAAAAAGGAAATAGC
TTCAAATTATAGTTTTTCCTCTATTATAGGTAAAAGTCAAAAGATAATAGAAAACATTGCTATAGCTAAAAAAGTAGCGC
CTACCTCTGCTAGTGTTCTTATTACAGGAGAAAGTGGAACAGGAAAAGAGGTTTTTGCAAAAGCTATACATAAAGCTAGT
GGAAGAACTGGAAACTTTGTAGCTATAAACTGTAGTGCTATACCTGAAAATCTTTTTGAAAGTGAATTGTTTGGTTATGT
AGGAGGAACTTTTACAGGCTCATTAAAAGAAGGGAAAATAGGTAAATTTGAATTTGCGAACAATGGTACTTTATTTTTAG
ATGAAATAGGAGACATGCCACTTAGTATGCAAGCAAAACTTTTAAGAGTTTTGCAAGATGGTGTGGTTTACAGAATAGGA
AGTCAAAAAGGTACAAAGGTTAATTGTAGAATTTTAGCTGCCACTAATAGAGACTTACAATCTATGATAAAGGAAAACAC
CTTTAGAGAAGACCTATTTTATAGATTTGCAGTAGTACATATAGAGTTACCTCCATTAAGGGAAAGAAGAGATGATATTA
AAGATTTTATAGACTTATTTATAAACCAAATATCAGAAAAGGAAGGTATAAAGATAAATACAATAGATAAAGAGGTTTAT
GACATTTTATGTTCTTATAAATGGGAAGGAAATATAAGGCAATTGAAAAATGTAGTGGAGAGGATGGTAGTTTTATCGAC
CAATGGAGAAGTAACAATATCTTCCGTTCCTAACCATATAGTGCAGGATGTAGAAGAAATTGAAGGGGAATCTCATCACA
GATATGATTTAAATGAAGTAGTTAAAAATACAGAAAAAAAGATAATAAAGGAAGTAATGGAAATAACCAAAGGCAATAAA
AAGAAAGCAGCGGAAATACTTAATATAAAAAGAAGTACTTTATATTATAAATTAAATCAGTATGATTTAATTTAA

Upstream 100 bases:

>100_bases
ATTAATTATGTTAAAATATATATATACTATATGATACCATAAACACAGCTTGCTATACAGAAATCTATATTATATTTATG
GTACATTGGAGGAATATAAG

Downstream 100 bases:

>100_bases
ATTTAAAAAAATTGATTTATTTGTATAATGTTAAAAAGTTTAAAGTATAATAAGTATAATAAATAAATATGGCTTTTTAT
ATAACATATTGTTATTGACA

Product: sensory box sigma-54 dependent transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MNSSIELIYTVKNVMKTDFIKVFKNEAISSAFNKMAKLYKDEVLIVDEDDNIIGIFTKNDLYKLENQGKKFSDNLENYIK
RDVITISEEKSIISARNIMVKNKIERLPIVHNRKIIGIVHLDDLNNELYTNVEELYVLQDRILENMHEAVCITNNKGVVI
YWNKSSEDLYGVKRQEIIGKYLGAFFPNALILKVLKNPRKITNVNNEPSPGKTVILSAVPIFNSKNKLIAVASTDRDITE
VISLSKELMQEKKKVEFFESAYKKEIASNYSFSSIIGKSQKIIENIAIAKKVAPTSASVLITGESGTGKEVFAKAIHKAS
GRTGNFVAINCSAIPENLFESELFGYVGGTFTGSLKEGKIGKFEFANNGTLFLDEIGDMPLSMQAKLLRVLQDGVVYRIG
SQKGTKVNCRILAATNRDLQSMIKENTFREDLFYRFAVVHIELPPLRERRDDIKDFIDLFINQISEKEGIKINTIDKEVY
DILCSYKWEGNIRQLKNVVERMVVLSTNGEVTISSVPNHIVQDVEEIEGESHHRYDLNEVVKNTEKKIIKEVMEITKGNK
KKAAEILNIKRSTLYYKLNQYDLI

Sequences:

>Translated_584_residues
MNSSIELIYTVKNVMKTDFIKVFKNEAISSAFNKMAKLYKDEVLIVDEDDNIIGIFTKNDLYKLENQGKKFSDNLENYIK
RDVITISEEKSIISARNIMVKNKIERLPIVHNRKIIGIVHLDDLNNELYTNVEELYVLQDRILENMHEAVCITNNKGVVI
YWNKSSEDLYGVKRQEIIGKYLGAFFPNALILKVLKNPRKITNVNNEPSPGKTVILSAVPIFNSKNKLIAVASTDRDITE
VISLSKELMQEKKKVEFFESAYKKEIASNYSFSSIIGKSQKIIENIAIAKKVAPTSASVLITGESGTGKEVFAKAIHKAS
GRTGNFVAINCSAIPENLFESELFGYVGGTFTGSLKEGKIGKFEFANNGTLFLDEIGDMPLSMQAKLLRVLQDGVVYRIG
SQKGTKVNCRILAATNRDLQSMIKENTFREDLFYRFAVVHIELPPLRERRDDIKDFIDLFINQISEKEGIKINTIDKEVY
DILCSYKWEGNIRQLKNVVERMVVLSTNGEVTISSVPNHIVQDVEEIEGESHHRYDLNEVVKNTEKKIIKEVMEITKGNK
KKAAEILNIKRSTLYYKLNQYDLI
>Mature_584_residues
MNSSIELIYTVKNVMKTDFIKVFKNEAISSAFNKMAKLYKDEVLIVDEDDNIIGIFTKNDLYKLENQGKKFSDNLENYIK
RDVITISEEKSIISARNIMVKNKIERLPIVHNRKIIGIVHLDDLNNELYTNVEELYVLQDRILENMHEAVCITNNKGVVI
YWNKSSEDLYGVKRQEIIGKYLGAFFPNALILKVLKNPRKITNVNNEPSPGKTVILSAVPIFNSKNKLIAVASTDRDITE
VISLSKELMQEKKKVEFFESAYKKEIASNYSFSSIIGKSQKIIENIAIAKKVAPTSASVLITGESGTGKEVFAKAIHKAS
GRTGNFVAINCSAIPENLFESELFGYVGGTFTGSLKEGKIGKFEFANNGTLFLDEIGDMPLSMQAKLLRVLQDGVVYRIG
SQKGTKVNCRILAATNRDLQSMIKENTFREDLFYRFAVVHIELPPLRERRDDIKDFIDLFINQISEKEGIKINTIDKEVY
DILCSYKWEGNIRQLKNVVERMVVLSTNGEVTISSVPNHIVQDVEEIEGESHHRYDLNEVVKNTEKKIIKEVMEITKGNK
KKAAEILNIKRSTLYYKLNQYDLI

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=345, Percent_Identity=43.768115942029, Blast_Score=287, Evalue=1e-78,
Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=43.3021806853583, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1790299, Length=368, Percent_Identity=36.1413043478261, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI1789087, Length=318, Percent_Identity=40.8805031446541, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI87082117, Length=369, Percent_Identity=37.940379403794, Blast_Score=237, Evalue=2e-63,
Organism=Escherichia coli, GI1790437, Length=345, Percent_Identity=40.2898550724638, Blast_Score=236, Evalue=4e-63,
Organism=Escherichia coli, GI1788905, Length=311, Percent_Identity=39.5498392282958, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1786524, Length=333, Percent_Identity=36.3363363363363, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI87082152, Length=292, Percent_Identity=39.3835616438356, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1787583, Length=316, Percent_Identity=36.0759493670886, Blast_Score=212, Evalue=5e-56,
Organism=Escherichia coli, GI87081872, Length=305, Percent_Identity=37.7049180327869, Blast_Score=208, Evalue=8e-55,
Organism=Escherichia coli, GI87081858, Length=412, Percent_Identity=26.2135922330097, Blast_Score=159, Evalue=7e-40,
Organism=Escherichia coli, GI1789828, Length=300, Percent_Identity=31, Blast_Score=144, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 66385; Mature: 66385

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSIELIYTVKNVMKTDFIKVFKNEAISSAFNKMAKLYKDEVLIVDEDDNIIGIFTKND
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCC
LYKLENQGKKFSDNLENYIKRDVITISEEKSIISARNIMVKNKIERLPIVHNRKIIGIVH
HHHHHCCCCHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHCCEEECCEEEEEEE
LDDLNNELYTNVEELYVLQDRILENMHEAVCITNNKGVVIYWNKSSEDLYGVKRQEIIGK
ECCCCCHHHCCHHHHHHHHHHHHHHHHHEEEEECCCEEEEEECCCCCCHHCCHHHHHHHH
YLGAFFPNALILKVLKNPRKITNVNNEPSPGKTVILSAVPIFNSKNKLIAVASTDRDITE
HHHHHCCHHHHHHHHHCCHHHCCCCCCCCCCCEEEEEEEEEECCCCCEEEEECCCCHHHH
VISLSKELMQEKKKVEFFESAYKKEIASNYSFSSIIGKSQKIIENIAIAKKVAPTSASVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCEEE
ITGESGTGKEVFAKAIHKASGRTGNFVAINCSAIPENLFESELFGYVGGTFTGSLKEGKI
EECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEECCCCCCCC
GKFEFANNGTLFLDEIGDMPLSMQAKLLRVLQDGVVYRIGSQKGTKVNCRILAATNRDLQ
CEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEEECCHHHH
SMIKENTFREDLFYRFAVVHIELPPLRERRDDIKDFIDLFINQISEKEGIKINTIDKEVY
HHHHHCCHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHH
DILCSYKWEGNIRQLKNVVERMVVLSTNGEVTISSVPNHIVQDVEEIEGESHHRYDLNEV
HHHHCCCCCCCHHHHHHHHHHHEEEECCCCEEEECCCHHHHHHHHHHCCCCCCCCCHHHH
VKNTEKKIIKEVMEITKGNKKKAAEILNIKRSTLYYKLNQYDLI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEECCCCCC
>Mature Secondary Structure
MNSSIELIYTVKNVMKTDFIKVFKNEAISSAFNKMAKLYKDEVLIVDEDDNIIGIFTKND
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCC
LYKLENQGKKFSDNLENYIKRDVITISEEKSIISARNIMVKNKIERLPIVHNRKIIGIVH
HHHHHCCCCHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHCCEEECCEEEEEEE
LDDLNNELYTNVEELYVLQDRILENMHEAVCITNNKGVVIYWNKSSEDLYGVKRQEIIGK
ECCCCCHHHCCHHHHHHHHHHHHHHHHHEEEEECCCEEEEEECCCCCCHHCCHHHHHHHH
YLGAFFPNALILKVLKNPRKITNVNNEPSPGKTVILSAVPIFNSKNKLIAVASTDRDITE
HHHHHCCHHHHHHHHHCCHHHCCCCCCCCCCCEEEEEEEEEECCCCCEEEEECCCCHHHH
VISLSKELMQEKKKVEFFESAYKKEIASNYSFSSIIGKSQKIIENIAIAKKVAPTSASVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCEEE
ITGESGTGKEVFAKAIHKASGRTGNFVAINCSAIPENLFESELFGYVGGTFTGSLKEGKI
EECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEECCCCCCCC
GKFEFANNGTLFLDEIGDMPLSMQAKLLRVLQDGVVYRIGSQKGTKVNCRILAATNRDLQ
CEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEEECCHHHH
SMIKENTFREDLFYRFAVVHIELPPLRERRDDIKDFIDLFINQISEKEGIKINTIDKEVY
HHHHHCCHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHH
DILCSYKWEGNIRQLKNVVERMVVLSTNGEVTISSVPNHIVQDVEEIEGESHHRYDLNEV
HHHHCCCCCCCHHHHHHHHHHHEEEECCCCEEEECCCHHHHHHHHHHCCCCCCCCCHHHH
VKNTEKKIIKEVMEITKGNKKKAAEILNIKRSTLYYKLNQYDLI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]