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The map label for this gene is glpX [H]

Identifier: 153930832

GI number: 153930832

Start: 2678088

End: 2679062

Strand: Reverse

Name: glpX [H]

Synonym: CLB_2558

Alternate gene names: 153930832

Gene position: 2679062-2678088 (Counterclockwise)

Preceding gene: 153933271

Following gene: 153933964

Centisome position: 69.34

GC content: 36.21

Gene sequence:

>975_bases
ATGCTAAATACAGATATTGCTATGGGACTTGCTAGAGTAACAGAAGCAGCAGCGTTAAGTGCATCAAAATTTATGGGTAG
AGGAGACAAAAATGCGGCGGATCAAGCAGCAGTGGATGGCATGCACAAAGCTTTTCAAATAATGCCCATAAGAGGTAAGG
TTGTTATAGGAGAAGGAGAATTAGATGAGGCTCCTATGCTATATATAGGTGAAGAAGTTGGAATTGGTGCAGAGGATATG
GTAGAAATGGATATAGCTGTAGATCCAGTAGATGGAACTAAACTTATAGCAAAGGGTTTAGAAAATGCTATAGCTGTGGT
AGCTATGGGACCTAAAGGAAGTTTATTTCATGCACCAGATATGTATATGAAGAAAATAGCTGTAGGAGCAGGGGCTAAGG
GAGCTATAGATATAAATAAATCCCCTAAAGAGAATATATTAAATGTAGCTAGAGCTCTAAATAAAGATGTAACAGAACTT
ACAGTTATAGTTCAAGAAAGAGATAGACATGATTATATAGTAAAAGATGCAAGAGAAGTAGGCGCTAGAGTTAAGCTTTT
TGGAGAAGGAGATGTAGCAGCAGTATTAGCCTGTGGATTTGAAGATACTGGAGTAGATATAATGATGGGAACCGGTGGAG
CTCCAGAAGGTGTTATAGCAGCAGCTGCCATAAAATGTATGGGCGGTGAAATGCAAGCACAACTTTGTCCAACTAGTCAA
GAAGAAATAGAAAGATGTAAGACTATGGGAATAAAAGATCATGAAGCTATACTTTATATAGATGATTTAGTAAAAAGTGA
TGATGTTTATTTTGCAGCTACAGCTATAACAGATTGTGATTTGTTAAAGGGAGTAGTTTACAATAGAAATGAAAAGGCTA
TTACAAATTCTATAGTTATGAGATCTAAAACTGGTACTATTAGATTTGTTAAAGCTTGTCATAACTTAGCTAAAAGCGCT
ATAGTAGTTGAATAA

Upstream 100 bases:

>100_bases
ATATGATATGCTAATTAAGAGATTTTAATGAAATAAAAGTAAAAAATATATATAAATTATTATTTGTATACAATAAACCA
TAATTTGAGGGGGAAAATAT

Downstream 100 bases:

>100_bases
AATAATCTAAAAAATTAATTTAGTTCTTTAATAATCCTTATATATAAAAAAAAGTATGTATTAAGATGTAGCTCTCTAAT
ACATACTTTTTTGATTTATA

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MLNTDIAMGLARVTEAAALSASKFMGRGDKNAADQAAVDGMHKAFQIMPIRGKVVIGEGELDEAPMLYIGEEVGIGAEDM
VEMDIAVDPVDGTKLIAKGLENAIAVVAMGPKGSLFHAPDMYMKKIAVGAGAKGAIDINKSPKENILNVARALNKDVTEL
TVIVQERDRHDYIVKDAREVGARVKLFGEGDVAAVLACGFEDTGVDIMMGTGGAPEGVIAAAAIKCMGGEMQAQLCPTSQ
EEIERCKTMGIKDHEAILYIDDLVKSDDVYFAATAITDCDLLKGVVYNRNEKAITNSIVMRSKTGTIRFVKACHNLAKSA
IVVE

Sequences:

>Translated_324_residues
MLNTDIAMGLARVTEAAALSASKFMGRGDKNAADQAAVDGMHKAFQIMPIRGKVVIGEGELDEAPMLYIGEEVGIGAEDM
VEMDIAVDPVDGTKLIAKGLENAIAVVAMGPKGSLFHAPDMYMKKIAVGAGAKGAIDINKSPKENILNVARALNKDVTEL
TVIVQERDRHDYIVKDAREVGARVKLFGEGDVAAVLACGFEDTGVDIMMGTGGAPEGVIAAAAIKCMGGEMQAQLCPTSQ
EEIERCKTMGIKDHEAILYIDDLVKSDDVYFAATAITDCDLLKGVVYNRNEKAITNSIVMRSKTGTIRFVKACHNLAKSA
IVVE
>Mature_324_residues
MLNTDIAMGLARVTEAAALSASKFMGRGDKNAADQAAVDGMHKAFQIMPIRGKVVIGEGELDEAPMLYIGEEVGIGAEDM
VEMDIAVDPVDGTKLIAKGLENAIAVVAMGPKGSLFHAPDMYMKKIAVGAGAKGAIDINKSPKENILNVARALNKDVTEL
TVIVQERDRHDYIVKDAREVGARVKLFGEGDVAAVLACGFEDTGVDIMMGTGGAPEGVIAAAAIKCMGGEMQAQLCPTSQ
EEIERCKTMGIKDHEAILYIDDLVKSDDVYFAATAITDCDLLKGVVYNRNEKAITNSIVMRSKTGTIRFVKACHNLAKSA
IVVE

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=330, Percent_Identity=44.8484848484849, Blast_Score=274, Evalue=5e-75,
Organism=Escherichia coli, GI1789298, Length=323, Percent_Identity=42.7244582043344, Blast_Score=240, Evalue=7e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 34435; Mature: 34435

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTDIAMGLARVTEAAALSASKFMGRGDKNAADQAAVDGMHKAFQIMPIRGKVVIGEGE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEEEECCEEEECCCC
LDEAPMLYIGEEVGIGAEDMVEMDIAVDPVDGTKLIAKGLENAIAVVAMGPKGSLFHAPD
CCCCCEEEECCCCCCCHHHHEEEEEEECCCCCHHHHHHHHCCEEEEEEECCCCCEEECCH
MYMKKIAVGAGAKGAIDINKSPKENILNVARALNKDVTELTVIVQERDRHDYIVKDAREV
HHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHEEEEEECCCCCCHHHHHHHHC
GARVKLFGEGDVAAVLACGFEDTGVDIMMGTGGAPEGVIAAAAIKCMGGEMQAQLCPTSQ
CCEEEEEECCCEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCH
EEIERCKTMGIKDHEAILYIDDLVKSDDVYFAATAITDCDLLKGVVYNRNEKAITNSIVM
HHHHHHHHCCCCCCCEEEEEEHHCCCCCEEEEEEECCHHHHHHHHHCCCCCHHHHHHEEE
RSKTGTIRFVKACHNLAKSAIVVE
ECCCCCHHHHHHHHHHHHCCEECC
>Mature Secondary Structure
MLNTDIAMGLARVTEAAALSASKFMGRGDKNAADQAAVDGMHKAFQIMPIRGKVVIGEGE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEEEECCEEEECCCC
LDEAPMLYIGEEVGIGAEDMVEMDIAVDPVDGTKLIAKGLENAIAVVAMGPKGSLFHAPD
CCCCCEEEECCCCCCCHHHHEEEEEEECCCCCHHHHHHHHCCEEEEEEECCCCCEEECCH
MYMKKIAVGAGAKGAIDINKSPKENILNVARALNKDVTELTVIVQERDRHDYIVKDAREV
HHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHEEEEEECCCCCCHHHHHHHHC
GARVKLFGEGDVAAVLACGFEDTGVDIMMGTGGAPEGVIAAAAIKCMGGEMQAQLCPTSQ
CCEEEEEECCCEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCH
EEIERCKTMGIKDHEAILYIDDLVKSDDVYFAATAITDCDLLKGVVYNRNEKAITNSIVM
HHHHHHHHCCCCCCCEEEEEEHHCCCCCEEEEEEECCHHHHHHHHHCCCCCHHHHHHEEE
RSKTGTIRFVKACHNLAKSAIVVE
ECCCCCHHHHHHHHHHHHCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]