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The map label for this gene is ntdR [H]

Identifier: 152976784

GI number: 152976784

Start: 3124925

End: 3126016

Strand: Reverse

Name: ntdR [H]

Synonym: Bcer98_3082

Alternate gene names: 152976784

Gene position: 3126016-3124925 (Counterclockwise)

Preceding gene: 152976785

Following gene: 152976783

Centisome position: 76.49

GC content: 34.07

Gene sequence:

>1092_bases
TTGAATTTTCCCCATATTTTTGTTCACCTCGTTTATAATAGATGTAAAACTTACAATATACTGTACATTCTGAAATGTAT
CACAGATCAAGGGGGAATTACCATTTCTACCATTGAAGATATTGCGAAGTTAGCTGGAGTATCAAAAGCGACGGTTTCTC
GAGTACTCAATCGTCATCCTTATGTCCGTCCAGAATTGCGGGCAAGGGTAGAAGCAATTATTGAGGAACAAAACTATGTA
CCAATAGCAACGGCTAAAGATTTGAGGCGTCTTCAAACAAATTTAGTTGGTGTAGTTGTTCCAAATATATATCATCCTTT
TTTTAGCCAGTTAATTCAAGAATTAAGTTATATATTAAAAAAAGATCATTACGATATTGTGATTTTACAGTCAAATTATG
AGATGGATAAGGAGAGAGAATTTTTACACTACATTAAGACGAAAAAATTAGATGCATTAATTTTTATGACACTTTCGTTA
CCGATTGGAGAAGTAGAAGAGGCAATGCACTTCGGGAAAATTGTTATTTGTAATGAACATGTTGAAACAGAAAAGATTTG
TACAGTTCAATTTAATGAAGAGTTAGCGGGATATATGGGAACGAAACATTTGATTGAAAAAGGATATACAAGGATAGGTT
TTTGTTACGATACATTAAAAAGTAAAGCACAGCGCCAAAGGTATAAAGGTTATAAAAGAGCATTAAAGGAATATGGCCTA
CAGTTACAGCAAGAATGGGTGTTTTCAAACTGTTTTGAATTAAAGGATGGAGAAAAGGTGATATATAGTATTTCCTCCAT
GCGCGATATTCCAGATGCAATCTTTACAGGTAGTGATGAAATAGCTGCAGGTATGATTATGACAGCACAACGATTACATA
TTCATGTTCCACAAGATTTAGGAGTGATTGGATTTGATAATCAACCTCTTTCAATGATTATGACTCCTAACATAACAACA
ATACAGACATCTATTAGAAGCATGGCCCAACATTCAATTTTTTTATTGCACAAACAGTCGCGAAAAGAACATGTACAGCA
AATCCGATTGCCAGTTGCGATAATAGAAAGAGAATCTACAAGAAGGAGGTAG

Upstream 100 bases:

>100_bases
ATAAAGGCAGCATAGAGATTTAGTTCCTCTGCACCACGTTTATCATTTGCAGTATGAAAAGCAACTTGCTTTTCCCTCAA
TAACTTCTTTCTGTTAAAAG

Downstream 100 bases:

>100_bases
TAGTATGTTTCATACAGATCGTTTGCAGTTTCGGAAATATACAATGGCTGATTTAGACTTTTATGCTTCGTTATGGGGAA
ATGAAAAAGTAATGCGCTAT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MNFPHIFVHLVYNRCKTYNILYILKCITDQGGITISTIEDIAKLAGVSKATVSRVLNRHPYVRPELRARVEAIIEEQNYV
PIATAKDLRRLQTNLVGVVVPNIYHPFFSQLIQELSYILKKDHYDIVILQSNYEMDKEREFLHYIKTKKLDALIFMTLSL
PIGEVEEAMHFGKIVICNEHVETEKICTVQFNEELAGYMGTKHLIEKGYTRIGFCYDTLKSKAQRQRYKGYKRALKEYGL
QLQQEWVFSNCFELKDGEKVIYSISSMRDIPDAIFTGSDEIAAGMIMTAQRLHIHVPQDLGVIGFDNQPLSMIMTPNITT
IQTSIRSMAQHSIFLLHKQSRKEHVQQIRLPVAIIERESTRRR

Sequences:

>Translated_363_residues
MNFPHIFVHLVYNRCKTYNILYILKCITDQGGITISTIEDIAKLAGVSKATVSRVLNRHPYVRPELRARVEAIIEEQNYV
PIATAKDLRRLQTNLVGVVVPNIYHPFFSQLIQELSYILKKDHYDIVILQSNYEMDKEREFLHYIKTKKLDALIFMTLSL
PIGEVEEAMHFGKIVICNEHVETEKICTVQFNEELAGYMGTKHLIEKGYTRIGFCYDTLKSKAQRQRYKGYKRALKEYGL
QLQQEWVFSNCFELKDGEKVIYSISSMRDIPDAIFTGSDEIAAGMIMTAQRLHIHVPQDLGVIGFDNQPLSMIMTPNITT
IQTSIRSMAQHSIFLLHKQSRKEHVQQIRLPVAIIERESTRRR
>Mature_363_residues
MNFPHIFVHLVYNRCKTYNILYILKCITDQGGITISTIEDIAKLAGVSKATVSRVLNRHPYVRPELRARVEAIIEEQNYV
PIATAKDLRRLQTNLVGVVVPNIYHPFFSQLIQELSYILKKDHYDIVILQSNYEMDKEREFLHYIKTKKLDALIFMTLSL
PIGEVEEAMHFGKIVICNEHVETEKICTVQFNEELAGYMGTKHLIEKGYTRIGFCYDTLKSKAQRQRYKGYKRALKEYGL
QLQQEWVFSNCFELKDGEKVIYSISSMRDIPDAIFTGSDEIAAGMIMTAQRLHIHVPQDLGVIGFDNQPLSMIMTPNITT
IQTSIRSMAQHSIFLLHKQSRKEHVQQIRLPVAIIERESTRRR

Specific function: Positively regulates the ntdABC operon and negatively regulates its own transcription. Binds to NTD to induce ntdABC transcription [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=331, Percent_Identity=31.1178247734139, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790369, Length=313, Percent_Identity=29.3929712460064, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787948, Length=330, Percent_Identity=28.4848484848485, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1788474, Length=295, Percent_Identity=28.8135593220339, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789202, Length=297, Percent_Identity=28.2828282828283, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1789068, Length=303, Percent_Identity=25.4125412541254, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787580, Length=316, Percent_Identity=27.8481012658228, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1786540, Length=342, Percent_Identity=25.1461988304094, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI48994940, Length=318, Percent_Identity=23.5849056603774, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1790715, Length=322, Percent_Identity=24.8447204968944, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787906, Length=233, Percent_Identity=23.6051502145923, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786268, Length=292, Percent_Identity=23.2876712328767, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790689, Length=329, Percent_Identity=23.1003039513678, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 42055; Mature: 42055

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFPHIFVHLVYNRCKTYNILYILKCITDQGGITISTIEDIAKLAGVSKATVSRVLNRHP
CCCHHHHHHHHHHHCCCCHHEEEEEECCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHCCC
YVRPELRARVEAIIEEQNYVPIATAKDLRRLQTNLVGVVVPNIYHPFFSQLIQELSYILK
CCCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHC
KDHYDIVILQSNYEMDKEREFLHYIKTKKLDALIFMTLSLPIGEVEEAMHFGKIVICNEH
CCCCEEEEEECCCCCCHHHHHHHHHHHHCHHEEEEEEECCCHHHHHHHHHCCEEEEECCC
VETEKICTVQFNEELAGYMGTKHLIEKGYTRIGFCYDTLKSKAQRQRYKGYKRALKEYGL
CCCCEEEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
QLQQEWVFSNCFELKDGEKVIYSISSMRDIPDAIFTGSDEIAAGMIMTAQRLHIHVPQDL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHCCCCHHHHHHHEEEEEEEEECCCCC
GVIGFDNQPLSMIMTPNITTIQTSIRSMAQHSIFLLHKQSRKEHVQQIRLPVAIIEREST
CEEEECCCCCEEEECCCCHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHCCHHEEECHHH
RRR
CCC
>Mature Secondary Structure
MNFPHIFVHLVYNRCKTYNILYILKCITDQGGITISTIEDIAKLAGVSKATVSRVLNRHP
CCCHHHHHHHHHHHCCCCHHEEEEEECCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHCCC
YVRPELRARVEAIIEEQNYVPIATAKDLRRLQTNLVGVVVPNIYHPFFSQLIQELSYILK
CCCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHC
KDHYDIVILQSNYEMDKEREFLHYIKTKKLDALIFMTLSLPIGEVEEAMHFGKIVICNEH
CCCCEEEEEECCCCCCHHHHHHHHHHHHCHHEEEEEEECCCHHHHHHHHHCCEEEEECCC
VETEKICTVQFNEELAGYMGTKHLIEKGYTRIGFCYDTLKSKAQRQRYKGYKRALKEYGL
CCCCEEEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
QLQQEWVFSNCFELKDGEKVIYSISSMRDIPDAIFTGSDEIAAGMIMTAQRLHIHVPQDL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHCCCCHHHHHHHEEEEEEEEECCCCC
GVIGFDNQPLSMIMTPNITTIQTSIRSMAQHSIFLLHKQSRKEHVQQIRLPVAIIEREST
CEEEECCCCCEEEECCCCHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHCCHHEEECHHH
RRR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]