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The map label for this gene is moeZ [H]

Identifier: 152974026

GI number: 152974026

Start: 188516

End: 189247

Strand: Direct

Name: moeZ [H]

Synonym: Bcer98_0178

Alternate gene names: 152974026

Gene position: 188516-189247 (Clockwise)

Preceding gene: 152974025

Following gene: 152974028

Centisome position: 4.61

GC content: 30.87

Gene sequence:

>732_bases
ATGATTAATTATGATATCCGTTATAGAAGGCAACTTATTATGGAAAGATTTGGGGAAGAAGGACAGAAGAAACTAGGGAA
TGCTAGGGTATTAGTTATTGGAGCTGGAGGCTTAGGTTCACCTATAATTTCATATTTATCTGCAGCTGGAGTAGGTAAAT
TAGGAATAGTAGATCATGATGTAATAGAAGAGAGTAATTTACAACGTCAAATTATACATAAAACATCGTTGTTGAATTAT
CCAAAAGTGAACTCTGCTGAGCGATTTGTAAATGAATTAAATCCCGCAGTTGAAACGGAAGTTTTTCAAATGAAATTAGA
TAAAGAAAAAGCACAACAACTTTTTAAAAATTATGATGTTGTTGTTGATGCAGTTGATAATTTGGAAACTCGTAAAATTA
TTAACGCTGTTTGCTCTGAAAATGACATACCATTTGTGCATGGTAGCATTTCTAATTTTGAGGGTCTTGTTACAACAATT
ACTCCAGATGTTAACCATTGCTATAATTGTATTTTCCCTAATAGTGATTTCGTTCATAAAGGTGAAATAGGTGTAATAGG
AGCGATTCCTGGGATTATTGGATCTATACAAGTATTAGAAGTTATTAAACTTATAGTTGGATTACCAGTTCTGAAAGATG
AAATTTTATATTATAATGGTCTGACACATGATTTGAGAAAGGTTAAAATTAATGTAAAAAGTTGTAATTGTTTTTCTAAA
GAAACTGTATAA

Upstream 100 bases:

>100_bases
AATGGCCAAAGAATTCATCCATTAATGCTTTAGTTGAACGCTTAGTTAACTTAGAAAAAAATATTGAAATAATTGTAGAG
TAAGAGAAGAGGAGAATATA

Downstream 100 bases:

>100_bases
TTAATTTAATATAATTATTGGATGTCACTTGGTCTAAGTATATTCATATACAATTAAATTTTGTTGGATATGGGGTCTAA
TGAAATTATTTATTAAATAT

Product: UBA/THIF-type NAD/FAD binding protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MINYDIRYRRQLIMERFGEEGQKKLGNARVLVIGAGGLGSPIISYLSAAGVGKLGIVDHDVIEESNLQRQIIHKTSLLNY
PKVNSAERFVNELNPAVETEVFQMKLDKEKAQQLFKNYDVVVDAVDNLETRKIINAVCSENDIPFVHGSISNFEGLVTTI
TPDVNHCYNCIFPNSDFVHKGEIGVIGAIPGIIGSIQVLEVIKLIVGLPVLKDEILYYNGLTHDLRKVKINVKSCNCFSK
ETV

Sequences:

>Translated_243_residues
MINYDIRYRRQLIMERFGEEGQKKLGNARVLVIGAGGLGSPIISYLSAAGVGKLGIVDHDVIEESNLQRQIIHKTSLLNY
PKVNSAERFVNELNPAVETEVFQMKLDKEKAQQLFKNYDVVVDAVDNLETRKIINAVCSENDIPFVHGSISNFEGLVTTI
TPDVNHCYNCIFPNSDFVHKGEIGVIGAIPGIIGSIQVLEVIKLIVGLPVLKDEILYYNGLTHDLRKVKINVKSCNCFSK
ETV
>Mature_243_residues
MINYDIRYRRQLIMERFGEEGQKKLGNARVLVIGAGGLGSPIISYLSAAGVGKLGIVDHDVIEESNLQRQIIHKTSLLNY
PKVNSAERFVNELNPAVETEVFQMKLDKEKAQQLFKNYDVVVDAVDNLETRKIINAVCSENDIPFVHGSISNFEGLVTTI
TPDVNHCYNCIFPNSDFVHKGEIGVIGAIPGIIGSIQVLEVIKLIVGLPVLKDEILYYNGLTHDLRKVKINVKSCNCFSK
ETV

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=221, Percent_Identity=41.1764705882353, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI4885649, Length=147, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=5e-15,
Organism=Homo sapiens, GI23510338, Length=172, Percent_Identity=26.7441860465116, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI23510340, Length=172, Percent_Identity=26.7441860465116, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI38045944, Length=169, Percent_Identity=26.0355029585799, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI38045942, Length=166, Percent_Identity=25.9036144578313, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI38045948, Length=167, Percent_Identity=28.7425149700599, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4885585, Length=149, Percent_Identity=27.5167785234899, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI225543285, Length=149, Percent_Identity=27.5167785234899, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI225543288, Length=149, Percent_Identity=27.5167785234899, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI150417996, Length=157, Percent_Identity=24.203821656051, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787048, Length=230, Percent_Identity=35.2173913043478, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI87082356, Length=232, Percent_Identity=34.4827586206897, Blast_Score=145, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17540406, Length=237, Percent_Identity=37.9746835443038, Blast_Score=165, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI193203301, Length=157, Percent_Identity=29.2993630573248, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71984476, Length=168, Percent_Identity=27.3809523809524, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321903, Length=245, Percent_Identity=35.9183673469388, Blast_Score=149, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6320598, Length=171, Percent_Identity=26.9005847953216, Blast_Score=85, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6325323, Length=153, Percent_Identity=30.718954248366, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322639, Length=176, Percent_Identity=25.5681818181818, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24582879, Length=243, Percent_Identity=40.7407407407407, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI28573937, Length=171, Percent_Identity=27.4853801169591, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24660640, Length=150, Percent_Identity=28, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129973, Length=162, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 27029; Mature: 27029

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINYDIRYRRQLIMERFGEEGQKKLGNARVLVIGAGGLGSPIISYLSAAGVGKLGIVDHD
CCCCCHHHHHHHHHHHHCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCHH
VIEESNLQRQIIHKTSLLNYPKVNSAERFVNELNPAVETEVFQMKLDKEKAQQLFKNYDV
HHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHCCCE
VVDAVDNLETRKIINAVCSENDIPFVHGSISNFEGLVTTITPDVNHCYNCIFPNSDFVHK
EEECHHCHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEECCCHHHHEEEECCCCCCEEC
GEIGVIGAIPGIIGSIQVLEVIKLIVGLPVLKDEILYYNGLTHDLRKVKINVKSCNCFSK
CCEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHEECCCCCCEEEEEEEEECCCCCCC
ETV
CCC
>Mature Secondary Structure
MINYDIRYRRQLIMERFGEEGQKKLGNARVLVIGAGGLGSPIISYLSAAGVGKLGIVDHD
CCCCCHHHHHHHHHHHHCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCHH
VIEESNLQRQIIHKTSLLNYPKVNSAERFVNELNPAVETEVFQMKLDKEKAQQLFKNYDV
HHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHCCCE
VVDAVDNLETRKIINAVCSENDIPFVHGSISNFEGLVTTITPDVNHCYNCIFPNSDFVHK
EEECHHCHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEECCCHHHHEEEECCCCCCEEC
GEIGVIGAIPGIIGSIQVLEVIKLIVGLPVLKDEILYYNGLTHDLRKVKINVKSCNCFSK
CCEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHEECCCCCCEEEEEEEEECCCCCCC
ETV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]