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The map label for this gene is pabC [H]

Identifier: 152969648

GI number: 152969648

Start: 1244219

End: 1245028

Strand: Direct

Name: pabC [H]

Synonym: KPN_01094

Alternate gene names: 152969648

Gene position: 1244219-1245028 (Clockwise)

Preceding gene: 152969647

Following gene: 152969649

Centisome position: 23.41

GC content: 59.63

Gene sequence:

>810_bases
ATGTTCTTGATAAACGGCGTTGTACAGGACACGTTGGCAGCGAACGATCGCGCCACCCAGTTTGGCGACGGCTGTTTTAC
CACCGCCCGCATCCAGCAAGGGCAGGTTGCGCTACTGGACGCCCATCTGCAGCGTTTGCAGACAACCTGTGAAAAATTAC
ATATCCCATTTAACGACTGGCTGACGCTGAGCGAAGAGATGCAGCGTCTGGCTCGGCCGCACGCGCAGGGCGTGCTCAAG
GTGACTCTCACCCGCGGCGTTGGGGGAAGGGGATACAGTACGGCAGGCTGCGTGTCGCCCACTCGCATTCTCAGCTTCTC
TCCATTCCCGGCGCATTATGCGCGCTGGCGGGAGGAGGGCATTACTCTGACCCAGAGTCCGGTGCCCCTGGGGCGCAACT
CCTGGCTTGCCGGCCTGAAGCACCTTAATCGCCTTGAGCAGGTGCTGATCCGCTCTCATCTTGAGCAGACGGACGCCGAT
GAGGCGCTGGTCCTTGACAGTGACGGGTGGCTTACGGAATGCTGTGCCGCGAATTTATTCTGGCGTCAGGGACGTGATGT
ATTTACTCCGCGACTCGATTATGCCGGGGTCAACGGCATTATGCGGCAGCGCTGTATCGCGCAGCTGGCACCATCGACGT
TTCGCGTTGTCGAAGTGACAGCGCGTCCCGAGACATTGCGGGAGGCCGATGAAGTGCTGATCTGCAATGCGCTGATGCCG
CTGGTGCCGGTTCGCCGCTGGGAGGAGACCACCTGGTCCTCGCGTGAGCTTTACCATTTTTTAGCCCCTTTGTGTGAGCT
GTCTGGTTAG

Upstream 100 bases:

>100_bases
ACAAAAGGCCCGTTCATCGGGCCTTTTTTATTCAGCTTTCTCCCCTTGTTCTCTGCTCTGGGTCCTGACACACTGACCGA
CCAGTGAAAAGGAGTCCTTT

Downstream 100 bases:

>100_bases
TATGAAGAAAATGTTACGTTTTATCCTGTTGCTGGTCGTGCTGTTGGGCATCGCCGCGGCGGCAGGCATGTGGAAGGTAC
GCCAGCTGGCGGACAGCAAG

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MFLINGVVQDTLAANDRATQFGDGCFTTARIQQGQVALLDAHLQRLQTTCEKLHIPFNDWLTLSEEMQRLARPHAQGVLK
VTLTRGVGGRGYSTAGCVSPTRILSFSPFPAHYARWREEGITLTQSPVPLGRNSWLAGLKHLNRLEQVLIRSHLEQTDAD
EALVLDSDGWLTECCAANLFWRQGRDVFTPRLDYAGVNGIMRQRCIAQLAPSTFRVVEVTARPETLREADEVLICNALMP
LVPVRRWEETTWSSRELYHFLAPLCELSG

Sequences:

>Translated_269_residues
MFLINGVVQDTLAANDRATQFGDGCFTTARIQQGQVALLDAHLQRLQTTCEKLHIPFNDWLTLSEEMQRLARPHAQGVLK
VTLTRGVGGRGYSTAGCVSPTRILSFSPFPAHYARWREEGITLTQSPVPLGRNSWLAGLKHLNRLEQVLIRSHLEQTDAD
EALVLDSDGWLTECCAANLFWRQGRDVFTPRLDYAGVNGIMRQRCIAQLAPSTFRVVEVTARPETLREADEVLICNALMP
LVPVRRWEETTWSSRELYHFLAPLCELSG
>Mature_269_residues
MFLINGVVQDTLAANDRATQFGDGCFTTARIQQGQVALLDAHLQRLQTTCEKLHIPFNDWLTLSEEMQRLARPHAQGVLK
VTLTRGVGGRGYSTAGCVSPTRILSFSPFPAHYARWREEGITLTQSPVPLGRNSWLAGLKHLNRLEQVLIRSHLEQTDAD
EALVLDSDGWLTECCAANLFWRQGRDVFTPRLDYAGVNGIMRQRCIAQLAPSTFRVVEVTARPETLREADEVLICNALMP
LVPVRRWEETTWSSRELYHFLAPLCELSG

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=266, Percent_Identity=64.2857142857143, Blast_Score=348, Evalue=2e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 30243; Mature: 30243

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLINGVVQDTLAANDRATQFGDGCFTTARIQQGQVALLDAHLQRLQTTCEKLHIPFNDW
CEEECHHHHHHHHCCCCCCCCCCCCEEEHECCCCCCHHHHHHHHHHHHHHHHCCCCHHHH
LTLSEEMQRLARPHAQGVLKVTLTRGVGGRGYSTAGCVSPTRILSFSPFPAHYARWREEG
HHHHHHHHHHHCHHHCCEEEEEEECCCCCCCCCCCCCCCHHHHEECCCCCHHHHHHHHHC
ITLTQSPVPLGRNSWLAGLKHLNRLEQVLIRSHLEQTDADEALVLDSDGWLTECCAANLF
CEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH
WRQGRDVFTPRLDYAGVNGIMRQRCIAQLAPSTFRVVEVTARPETLREADEVLICNALMP
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHEEHHHHHHH
LVPVRRWEETTWSSRELYHFLAPLCELSG
HHHHHHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFLINGVVQDTLAANDRATQFGDGCFTTARIQQGQVALLDAHLQRLQTTCEKLHIPFNDW
CEEECHHHHHHHHCCCCCCCCCCCCEEEHECCCCCCHHHHHHHHHHHHHHHHCCCCHHHH
LTLSEEMQRLARPHAQGVLKVTLTRGVGGRGYSTAGCVSPTRILSFSPFPAHYARWREEG
HHHHHHHHHHHCHHHCCEEEEEEECCCCCCCCCCCCCCCHHHHEECCCCCHHHHHHHHHC
ITLTQSPVPLGRNSWLAGLKHLNRLEQVLIRSHLEQTDADEALVLDSDGWLTECCAANLF
CEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH
WRQGRDVFTPRLDYAGVNGIMRQRCIAQLAPSTFRVVEVTARPETLREADEVLICNALMP
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHEEHHHHHHH
LVPVRRWEETTWSSRELYHFLAPLCELSG
HHHHHHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644759; 8905232; 9278503; 2071583; 2251281; 10876155 [H]