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The map label for this gene is yafC [C]

Identifier: 152969607

GI number: 152969607

Start: 1202757

End: 1203449

Strand: Direct

Name: yafC [C]

Synonym: KPN_01052

Alternate gene names: 152969607

Gene position: 1202757-1203449 (Clockwise)

Preceding gene: 152969604

Following gene: 152969610

Centisome position: 22.63

GC content: 65.37

Gene sequence:

>693_bases
ATGCTGATTGAGGCCGAGGCGGCGCAGCAGGCGGTCGAGACGCTGCGCGCCGAGCCGCGCGGTAGCGTCAGGATCACCTG
TCCGGTCACCTTGCTGCATGTCCATATCGGACCGATGCTGGCGCGATTTATGGCGCGCTATCCTGGGGTAACGCTGCATC
TTGAGGCGACCAACCGCCGGGTGGATGTGGTCGGGGAGGGCATTGATGTGGCGATCCGCGTCCGTCCCCGGCCCATCGAG
GATAGCGACCTGGTGATGCGCGTGCTGGCGGACCGCGGGCACCGGCTGGTGGCCAGCCCGGATCTCATTTCCCGGCTCGG
ACGTCCGCAGGCGCCGTCCGAGCTGAGCGCCTGGCCGGGCCTCAGCCTGGGTGCGAACAAGCATCAGCATAAATGGCAGC
TCACCGGGCCCGGGGGAGCGAGAGCGGAAGTGTATTTCACGCCGCGAATGGTGACCACCGATATGCTGGCGCTGCGCGAG
GCGGCGATGGCCGGCGTAGGCGTGGTGCAGCTTCCTTTATTAATGGTGCGCGATCAGCTGGCGTCAGGTGAATTAGAGGT
GGTTCTGGACGAGTGGCAGCCGCGGCGGGAAGTGATCCATGCGGTATTTGCCTCACGGCGCGGGCTGCTGCCCTCCGTCA
GGGCGCTGGTGGACTACCTCAGTGAAGAGTATCAGCGGATGGAGGAAGATTGA

Upstream 100 bases:

>100_bases
GCAACTCGAGGAGCGGTTGGGCGTGCGTTTGATTCAGCGAACCACCCGTCAGTTCGCGGTCACCGAGGTCGGGCAGACCT
TTTATCAGCATTGCAAAGCG

Downstream 100 bases:

>100_bases
TGGGTAGGCAGAGGTTTTTTGTCGGAACTCATATGTGAAAAGCGTCCGTACTTTTTCACGCACTCTTCGCAATCGCGTAG
GCTCGTGAAAGATTGCTCAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MLIEAEAAQQAVETLRAEPRGSVRITCPVTLLHVHIGPMLARFMARYPGVTLHLEATNRRVDVVGEGIDVAIRVRPRPIE
DSDLVMRVLADRGHRLVASPDLISRLGRPQAPSELSAWPGLSLGANKHQHKWQLTGPGGARAEVYFTPRMVTTDMLALRE
AAMAGVGVVQLPLLMVRDQLASGELEVVLDEWQPRREVIHAVFASRRGLLPSVRALVDYLSEEYQRMEED

Sequences:

>Translated_230_residues
MLIEAEAAQQAVETLRAEPRGSVRITCPVTLLHVHIGPMLARFMARYPGVTLHLEATNRRVDVVGEGIDVAIRVRPRPIE
DSDLVMRVLADRGHRLVASPDLISRLGRPQAPSELSAWPGLSLGANKHQHKWQLTGPGGARAEVYFTPRMVTTDMLALRE
AAMAGVGVVQLPLLMVRDQLASGELEVVLDEWQPRREVIHAVFASRRGLLPSVRALVDYLSEEYQRMEED
>Mature_230_residues
MLIEAEAAQQAVETLRAEPRGSVRITCPVTLLHVHIGPMLARFMARYPGVTLHLEATNRRVDVVGEGIDVAIRVRPRPIE
DSDLVMRVLADRGHRLVASPDLISRLGRPQAPSELSAWPGLSLGANKHQHKWQLTGPGGARAEVYFTPRMVTTDMLALRE
AAMAGVGVVQLPLLMVRDQLASGELEVVLDEWQPRREVIHAVFASRRGLLPSVRALVDYLSEEYQRMEED

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=237, Percent_Identity=28.6919831223629, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1789639, Length=224, Percent_Identity=25.4464285714286, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1787128, Length=213, Percent_Identity=23.4741784037559, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI87081978, Length=214, Percent_Identity=29.4392523364486, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789440, Length=183, Percent_Identity=27.8688524590164, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI145693193, Length=202, Percent_Identity=26.7326732673267, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787589, Length=224, Percent_Identity=24.5535714285714, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 25543; Mature: 25543

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIEAEAAQQAVETLRAEPRGSVRITCPVTLLHVHIGPMLARFMARYPGVTLHLEATNRR
CEECHHHHHHHHHHHHCCCCCCEEEEECCEEEHHHHHHHHHHHHHHCCCEEEEEECCCCE
VDVVGEGIDVAIRVRPRPIEDSDLVMRVLADRGHRLVASPDLISRLGRPQAPSELSAWPG
EEEEECCEEEEEEECCCCCCHHHHHHHHHHHCCCEEEECCHHHHHCCCCCCCCHHHCCCC
LSLGANKHQHKWQLTGPGGARAEVYFTPRMVTTDMLALREAAMAGVGVVQLPLLMVRDQL
CCCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ASGELEVVLDEWQPRREVIHAVFASRRGLLPSVRALVDYLSEEYQRMEED
CCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLIEAEAAQQAVETLRAEPRGSVRITCPVTLLHVHIGPMLARFMARYPGVTLHLEATNRR
CEECHHHHHHHHHHHHCCCCCCEEEEECCEEEHHHHHHHHHHHHHHCCCEEEEEECCCCE
VDVVGEGIDVAIRVRPRPIEDSDLVMRVLADRGHRLVASPDLISRLGRPQAPSELSAWPG
EEEEECCEEEEEEECCCCCCHHHHHHHHHHHCCCEEEECCHHHHHCCCCCCCCHHHCCCC
LSLGANKHQHKWQLTGPGGARAEVYFTPRMVTTDMLALREAAMAGVGVVQLPLLMVRDQL
CCCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ASGELEVVLDEWQPRREVIHAVFASRRGLLPSVRALVDYLSEEYQRMEED
CCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]