Click here to switch to the map view.

The map label for this gene is tolC [C]

Identifier: 152969552

GI number: 152969552

Start: 1141691

End: 1143127

Strand: Direct

Name: tolC [C]

Synonym: KPN_00995

Alternate gene names: 152969552

Gene position: 1141691-1143127 (Clockwise)

Preceding gene: 152969551

Following gene: 152969553

Centisome position: 21.48

GC content: 51.7

Gene sequence:

>1437_bases
ATGCGTCTATTTCAAAAAAAAGGGATGGTCAGCGTTTACAGCTGCAGCACTATTTTCCTGTCAATCTGCGTGGTATTAAC
GGTTGACGCAGAGGAGCTTTCTTTTCCGCCCACCAGCATCAGCACCCAGAGGTTAAACGATACTCAGCAGGTCGCCGGTT
ATAGCGAAGAGCTTATCAACCCTGAAAGTCATCTTGCCGGTCCACTGGATATAGCTACCGCAGTAAAATCAGCAGTCAAT
TGGCATCCTGCTATCAATCAACAGGTGAGTAAACTTCAGGAGCAGGTGCAAAAAGTGGATGTAGCGAAAGCCAAATATTA
TCCGCAGGTTAATGCGGGTATGAATAATGGGTACAGTAACACCTACTCTGATTCTGGATATTCCCCCTCATTAGTTGTCT
CTGTTTCGCAAATGCTGTACGACTTTGGCAAAGTCTCCAGTTCGGTGAGAGCGGCGGACGCTGCCGTTGCCCAACAGCAG
GCGATGGTCATGCTTAATATCGATCAGGTGGCTCATGATACCGCGGGTGCAGTGGTACAGCTGCAAGGTTATCAAAAGCT
CGTGAAAATAGCCCAGGCCCAGGTCGATTCGTTAAAGCATATTGGCGATCTTATTCGCCAGCGCAACGACGCCGGGGCGA
CATCGCTTTCTGATGTTGTGCAGACGGATACCCGCGTTGAGGGTGCGCAGGCGACGCTTATCCAGTATCAGGCAGCGCTT
GAGCGCTGGAAGGCAACGCTGGCGACGTATCTTGGTCTCGGAAGTATTACCTCCGTAACCGAAAGCGTACCGCAGGCTAT
GGATGCCGCCTGCGCCGTTAGTAAAATCGATTATCGAACCGTACCAGCGGTGCTCGCCGCTTTGGCCCAAGCTACACAGG
CACAAGCCCAGGTAGATAATGCCACCGCGCAAATGTTGCCTACAATCTCGCTGGAACCTCAGGTAACGCATTACCTCAAT
GATAATTACGCCAACAGCGCGGTATTAAATAAAACGCAGTATTCGGCATGGGTCAAAGTAGAAATGCCGATCTACCAGGG
CGGCGCGCTAACGGCTTCCCGCGAAGCGGCGCAGCAAACGCTATCTGCGGCGAATGCCGGGATCAGAAACGCGCAACTCG
ATGCCAGCCAGAAGTTGAGCGCCTCCCGCGACGAGGCGGTAAACCTGAAACAATCTATCGCCATCCAGCGCCGCCAGCAA
TTGCTTGGCGAACAAACCCGCGCCCTGTATCAGGATCAATATTTACAGCTCGGCACGCGTCCGTTACTCGACCTGCTTAA
CGTCGATCAGGAAATTTATCAGGCGCAATTTAATCAGGTATTAACTGAAGCGCAACTGCGAAATCTGGAACTGGACTGTC
TGTTCAGTACAGGGAAAATGCGCGCCGTTTTTGCTCTGGATAACCAAAGAATTCAGGGCGTGGAGATTCGACCATGA

Upstream 100 bases:

>100_bases
GGAAAAACCAATCGGGGAACGACGGGCTATCGTTAAATAAAAAGAATGATGCGGAAAGAGTATATCCATATTTTCAGTTT
GCTTTCTGAAGGGTAATTTT

Downstream 100 bases:

>100_bases
GCGAACAACCCCAGCGCAGCGATATTCCGCATTTACAGGATTGGGCTAACGCTATGGCTTTTGTCGCCAGCCATTATCGG
CAAAGTTACTCACCGGGGAC

Product: putative outer membrane efflux protein

Products: NA

Alternate protein names: Outer Membrane Efflux Protein; Outer Membrane Efflux SS; Type I Secretion Protein; Outer Membrane Protein; Outer Membrane Transport Protein Type I Secretion; Outer Membrane Efflux Protein Type I Secretion Protein; HAS ABC Exporter Outer Membrane Component; Outer Membrane Export Protein; Type I Secretion Outer Membrane Protein; Type I Secretion Outer Membrane Protein lC Family; HAS ABC Exporter Outer Membrane Component Protein; RND Efflux Transporter

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MRLFQKKGMVSVYSCSTIFLSICVVLTVDAEELSFPPTSISTQRLNDTQQVAGYSEELINPESHLAGPLDIATAVKSAVN
WHPAINQQVSKLQEQVQKVDVAKAKYYPQVNAGMNNGYSNTYSDSGYSPSLVVSVSQMLYDFGKVSSSVRAADAAVAQQQ
AMVMLNIDQVAHDTAGAVVQLQGYQKLVKIAQAQVDSLKHIGDLIRQRNDAGATSLSDVVQTDTRVEGAQATLIQYQAAL
ERWKATLATYLGLGSITSVTESVPQAMDAACAVSKIDYRTVPAVLAALAQATQAQAQVDNATAQMLPTISLEPQVTHYLN
DNYANSAVLNKTQYSAWVKVEMPIYQGGALTASREAAQQTLSAANAGIRNAQLDASQKLSASRDEAVNLKQSIAIQRRQQ
LLGEQTRALYQDQYLQLGTRPLLDLLNVDQEIYQAQFNQVLTEAQLRNLELDCLFSTGKMRAVFALDNQRIQGVEIRP

Sequences:

>Translated_478_residues
MRLFQKKGMVSVYSCSTIFLSICVVLTVDAEELSFPPTSISTQRLNDTQQVAGYSEELINPESHLAGPLDIATAVKSAVN
WHPAINQQVSKLQEQVQKVDVAKAKYYPQVNAGMNNGYSNTYSDSGYSPSLVVSVSQMLYDFGKVSSSVRAADAAVAQQQ
AMVMLNIDQVAHDTAGAVVQLQGYQKLVKIAQAQVDSLKHIGDLIRQRNDAGATSLSDVVQTDTRVEGAQATLIQYQAAL
ERWKATLATYLGLGSITSVTESVPQAMDAACAVSKIDYRTVPAVLAALAQATQAQAQVDNATAQMLPTISLEPQVTHYLN
DNYANSAVLNKTQYSAWVKVEMPIYQGGALTASREAAQQTLSAANAGIRNAQLDASQKLSASRDEAVNLKQSIAIQRRQQ
LLGEQTRALYQDQYLQLGTRPLLDLLNVDQEIYQAQFNQVLTEAQLRNLELDCLFSTGKMRAVFALDNQRIQGVEIRP
>Mature_478_residues
MRLFQKKGMVSVYSCSTIFLSICVVLTVDAEELSFPPTSISTQRLNDTQQVAGYSEELINPESHLAGPLDIATAVKSAVN
WHPAINQQVSKLQEQVQKVDVAKAKYYPQVNAGMNNGYSNTYSDSGYSPSLVVSVSQMLYDFGKVSSSVRAADAAVAQQQ
AMVMLNIDQVAHDTAGAVVQLQGYQKLVKIAQAQVDSLKHIGDLIRQRNDAGATSLSDVVQTDTRVEGAQATLIQYQAAL
ERWKATLATYLGLGSITSVTESVPQAMDAACAVSKIDYRTVPAVLAALAQATQAQAQVDNATAQMLPTISLEPQVTHYLN
DNYANSAVLNKTQYSAWVKVEMPIYQGGALTASREAAQQTLSAANAGIRNAQLDASQKLSASRDEAVNLKQSIAIQRRQQ
LLGEQTRALYQDQYLQLGTRPLLDLLNVDQEIYQAQFNQVLTEAQLRNLELDCLFSTGKMRAVFALDNQRIQGVEIRP

Specific function: Required For Proper Expression Of Outer Membrane Protein Genes Such As Ompf, Nmpc, Protein 2, Hemolysin, Colicin V, Or Colicin E1. May Be Specialized For Signal Sequence Independent, Extracellular Secretion In Gram-Negative Bacteria. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Outer Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 52070; Mature: 52070

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLFQKKGMVSVYSCSTIFLSICVVLTVDAEELSFPPTSISTQRLNDTQQVAGYSEELIN
CCCCHHCCCEEEEHHHHHHHHHHHHHEECHHHHCCCCCCCCHHHCCCHHHHCCCHHHHCC
PESHLAGPLDIATAVKSAVNWHPAINQQVSKLQEQVQKVDVAKAKYYPQVNAGMNNGYSN
CHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
TYSDSGYSPSLVVSVSQMLYDFGKVSSSVRAADAAVAQQQAMVMLNIDQVAHDTAGAVVQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHCCCCCEEE
LQGYQKLVKIAQAQVDSLKHIGDLIRQRNDAGATSLSDVVQTDTRVEGAQATLIQYQAAL
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
ERWKATLATYLGLGSITSVTESVPQAMDAACAVSKIDYRTVPAVLAALAQATQAQAQVDN
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ATAQMLPTISLEPQVTHYLNDNYANSAVLNKTQYSAWVKVEMPIYQGGALTASREAAQQT
HHHHHCCCCCCCCCHHHHHCCCCCCHHHCCCCCCCEEEEEEECEECCCCCCHHHHHHHHH
LSAANAGIRNAQLDASQKLSASRDEAVNLKQSIAIQRRQQLLGEQTRALYQDQYLQLGTR
HHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
PLLDLLNVDQEIYQAQFNQVLTEAQLRNLELDCLFSTGKMRAVFALDNQRIQGVEIRP
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEECCCCCCCEECCC
>Mature Secondary Structure
MRLFQKKGMVSVYSCSTIFLSICVVLTVDAEELSFPPTSISTQRLNDTQQVAGYSEELIN
CCCCHHCCCEEEEHHHHHHHHHHHHHEECHHHHCCCCCCCCHHHCCCHHHHCCCHHHHCC
PESHLAGPLDIATAVKSAVNWHPAINQQVSKLQEQVQKVDVAKAKYYPQVNAGMNNGYSN
CHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
TYSDSGYSPSLVVSVSQMLYDFGKVSSSVRAADAAVAQQQAMVMLNIDQVAHDTAGAVVQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHCCCCCEEE
LQGYQKLVKIAQAQVDSLKHIGDLIRQRNDAGATSLSDVVQTDTRVEGAQATLIQYQAAL
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
ERWKATLATYLGLGSITSVTESVPQAMDAACAVSKIDYRTVPAVLAALAQATQAQAQVDN
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ATAQMLPTISLEPQVTHYLNDNYANSAVLNKTQYSAWVKVEMPIYQGGALTASREAAQQT
HHHHHCCCCCCCCCHHHHHCCCCCCHHHCCCCCCCEEEEEEECEECCCCCCHHHHHHHHH
LSAANAGIRNAQLDASQKLSASRDEAVNLKQSIAIQRRQQLLGEQTRALYQDQYLQLGTR
HHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
PLLDLLNVDQEIYQAQFNQVLTEAQLRNLELDCLFSTGKMRAVFALDNQRIQGVEIRP
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEECCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA