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The map label for this gene is hipO [H]

Identifier: 152969523

GI number: 152969523

Start: 1096243

End: 1097409

Strand: Direct

Name: hipO [H]

Synonym: KPN_00966

Alternate gene names: 152969523

Gene position: 1096243-1097409 (Clockwise)

Preceding gene: 152969522

Following gene: 152969525

Centisome position: 20.62

GC content: 53.38

Gene sequence:

>1167_bases
ATGAATCAGCAACAGCTAAAGCAGCAGCTTATCGCCTGGCGTCACTATTTGCATGCCCATCCGGAAAGCGCCTTCGAGGA
GCAGAATACTTCACGGTTTATTGCCGAAAAGCTCGAAGCTATGGGCATTGAGGTGCACCGCGATATTGGCAAAACCGGGG
TGGTGGGGAGATTGAAATGCGGCGACGGGAAGGGCGTTATCGCTATTCGTGCCGATATCGATGCCATTCAATTGACCGAA
CAGGGAGACTGGTCTTACCGCTCCATGACCGCCGAGCGGATGCACGGCTGCGGACATGATGGTCATACCTGCATTGCGCT
GGGCGCGGCGCAGTTGCTATTGCAGCGGCAGAATTTTAACGGCACGGTCTGCTTTGTTTTTCAGCCTGCTGAGGAACCTG
GCTATGGCGCCAGAGCGATGATGGACGATGGCGTTATTGAACGCTTTGGCATAGAGGAAATCTACGGTCTGCATAATATG
CCGGGTATGAAAGCCGGGACTATCGCCACGCGAGTCGGTGGCATTATGGCCAGTGAAGATAACTTTATTATTCGTATTAA
AGGGCAGGGAGCGCATGCGGCGCGGCCGCATATGGCGAAAGATCCGCTGGTCATTGCGGCGGAAATCATCCTGGCTTTGC
AGACAATTGTTTCGCGAAATGTTGATCCGAACGTGCCAGCGGTCATTTCCTGTACTGAACTGCACACCGATGGCATCCGC
AATGCGATTCCGACGCACGTCGAAATCAAAGGGGATACGCGCAGCTTTGCACCGGAGGTGCAGATGCTGCTCGAAGAACG
AATGCGTACCATTAGCGAAGCGATTTGCGCGATGCACGGTGCGACGTGCCAGTTCAGCTATACCCATGAATTTGCGCCAA
CGGTGAACTGGCAGCAATGCGTTGATGTAGCGGTCACCGCTGCGATTAACGTGGTAGGGGCTGAGAAGGTGGACGGCAAC
GTCGCACAGATGATGATTTCGGAGGATTTTGGCGCTTTTCTGCAAAAAATCCCCGGCTGTTTCATCTTTTTAGGCAACGG
CGATAGTTCAGATGCTCAGGGCAATACACCGTTGCATAATGCCTGCTACGACTTTAATGATGAGATATTGCTAACTGGCG
CGGAGTATTTTGCCGAGGTCGTCAGAGCCCGTTTGCCGCAGGAGTGA

Upstream 100 bases:

>100_bases
ACATAGCGCAGCCAAAGATCTGATTGCTGGCGCCAATGTGCTGCTGCAGGTGGTTTTACAGCGCGCCCAGCGTATGGACT
AATGTTTACAGGAGCAGAGA

Downstream 100 bases:

>100_bases
TATTGATTGGCCCGATAGCAGAATGCCGTCGGGCCATGTTTTTTAGCTTGCCTTTTTAATCGGCGGCAGGTCGAAAGCCT
CGCGCAGGGCGCGGACGAAG

Product: putative peptidase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNQQQLKQQLIAWRHYLHAHPESAFEEQNTSRFIAEKLEAMGIEVHRDIGKTGVVGRLKCGDGKGVIAIRADIDAIQLTE
QGDWSYRSMTAERMHGCGHDGHTCIALGAAQLLLQRQNFNGTVCFVFQPAEEPGYGARAMMDDGVIERFGIEEIYGLHNM
PGMKAGTIATRVGGIMASEDNFIIRIKGQGAHAARPHMAKDPLVIAAEIILALQTIVSRNVDPNVPAVISCTELHTDGIR
NAIPTHVEIKGDTRSFAPEVQMLLEERMRTISEAICAMHGATCQFSYTHEFAPTVNWQQCVDVAVTAAINVVGAEKVDGN
VAQMMISEDFGAFLQKIPGCFIFLGNGDSSDAQGNTPLHNACYDFNDEILLTGAEYFAEVVRARLPQE

Sequences:

>Translated_388_residues
MNQQQLKQQLIAWRHYLHAHPESAFEEQNTSRFIAEKLEAMGIEVHRDIGKTGVVGRLKCGDGKGVIAIRADIDAIQLTE
QGDWSYRSMTAERMHGCGHDGHTCIALGAAQLLLQRQNFNGTVCFVFQPAEEPGYGARAMMDDGVIERFGIEEIYGLHNM
PGMKAGTIATRVGGIMASEDNFIIRIKGQGAHAARPHMAKDPLVIAAEIILALQTIVSRNVDPNVPAVISCTELHTDGIR
NAIPTHVEIKGDTRSFAPEVQMLLEERMRTISEAICAMHGATCQFSYTHEFAPTVNWQQCVDVAVTAAINVVGAEKVDGN
VAQMMISEDFGAFLQKIPGCFIFLGNGDSSDAQGNTPLHNACYDFNDEILLTGAEYFAEVVRARLPQE
>Mature_388_residues
MNQQQLKQQLIAWRHYLHAHPESAFEEQNTSRFIAEKLEAMGIEVHRDIGKTGVVGRLKCGDGKGVIAIRADIDAIQLTE
QGDWSYRSMTAERMHGCGHDGHTCIALGAAQLLLQRQNFNGTVCFVFQPAEEPGYGARAMMDDGVIERFGIEEIYGLHNM
PGMKAGTIATRVGGIMASEDNFIIRIKGQGAHAARPHMAKDPLVIAAEIILALQTIVSRNVDPNVPAVISCTELHTDGIR
NAIPTHVEIKGDTRSFAPEVQMLLEERMRTISEAICAMHGATCQFSYTHEFAPTVNWQQCVDVAVTAAINVVGAEKVDGN
VAQMMISEDFGAFLQKIPGCFIFLGNGDSSDAQGNTPLHNACYDFNDEILLTGAEYFAEVVRARLPQE

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=435, Percent_Identity=26.2068965517241, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787598, Length=192, Percent_Identity=34.375, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 42495; Mature: 42495

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQQLKQQLIAWRHYLHAHPESAFEEQNTSRFIAEKLEAMGIEVHRDIGKTGVVGRLKC
CCHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEE
GDGKGVIAIRADIDAIQLTEQGDWSYRSMTAERMHGCGHDGHTCIALGAAQLLLQRQNFN
CCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCC
GTVCFVFQPAEEPGYGARAMMDDGVIERFGIEEIYGLHNMPGMKAGTIATRVGGIMASED
CEEEEEEECCCCCCCCCHHHHCCCHHHHHCHHHHHHCCCCCCCCCCHHHHHHCCEEECCC
NFIIRIKGQGAHAARPHMAKDPLVIAAEIILALQTIVSRNVDPNVPAVISCTELHTDGIR
CEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHH
NAIPTHVEIKGDTRSFAPEVQMLLEERMRTISEAICAMHGATCQFSYTHEFAPTVNWQQC
HCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHH
VDVAVTAAINVVGAEKVDGNVAQMMISEDFGAFLQKIPGCFIFLGNGDSSDAQGNTPLHN
HHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHH
ACYDFNDEILLTGAEYFAEVVRARLPQE
CCCCCCCCEEEECHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNQQQLKQQLIAWRHYLHAHPESAFEEQNTSRFIAEKLEAMGIEVHRDIGKTGVVGRLKC
CCHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEE
GDGKGVIAIRADIDAIQLTEQGDWSYRSMTAERMHGCGHDGHTCIALGAAQLLLQRQNFN
CCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCC
GTVCFVFQPAEEPGYGARAMMDDGVIERFGIEEIYGLHNMPGMKAGTIATRVGGIMASED
CEEEEEEECCCCCCCCCHHHHCCCHHHHHCHHHHHHCCCCCCCCCCHHHHHHCCEEECCC
NFIIRIKGQGAHAARPHMAKDPLVIAAEIILALQTIVSRNVDPNVPAVISCTELHTDGIR
CEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHH
NAIPTHVEIKGDTRSFAPEVQMLLEERMRTISEAICAMHGATCQFSYTHEFAPTVNWQQC
HCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHH
VDVAVTAAINVVGAEKVDGNVAQMMISEDFGAFLQKIPGCFIFLGNGDSSDAQGNTPLHN
HHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHH
ACYDFNDEILLTGAEYFAEVVRARLPQE
CCCCCCCCEEEECHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]