| Definition | Klebsiella pneumoniae subsp. pneumoniae MGH 78578 chromosome, complete genome. |
|---|---|
| Accession | NC_009648 |
| Length | 5,315,120 |
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The map label for this gene is hsdM [C]
Identifier: 152969515
GI number: 152969515
Start: 1081394
End: 1083421
Strand: Direct
Name: hsdM [C]
Synonym: KPN_00958
Alternate gene names: 152969515
Gene position: 1081394-1083421 (Clockwise)
Preceding gene: 152969511
Following gene: 152969516
Centisome position: 20.35
GC content: 56.8
Gene sequence:
>2028_bases ATGAACGAATTTACGGGATCGGCAGCTTCACAGGCTGACTTTATTTGGAAGAATGCGGAAGACCTGTGGGGTGACTTCAA GCATACGGACTTTGGCAAGATCATCTTGCCGTTTACCCTGCTACGCCGTCTGGAGTGTGCGCTGGAGCCGACCCGCGAGG CGGTGAGAGAAGCGCATGACGCTTTCAAGGATGCCGATGTTGAGCTGGATACCATTCTGCGCTCAACCGCTGAATACCCC TTCTACAACACCTCTGAATACTCCCTCGGCACCCTGGGTAGCACCAAGACGCGCCGCAATCTGGAAGACTACATCGCCCT GTTTTCGGATAACGCCCGCGCTATCTTCGAGGAGTTTGAGTTTGGCAATACGGTGATCCGGCTGGAGAAAGCGGGCTTGC TGTATAAGATTTGCCAGAACTTCGCCAAGATCGACCTGCACCCGGACGTGGTGCCGGATCGGGTGATGAGTAACATCTAC GAACACCTGATCCGCCGCTTTGGTGCTGAGGTCAATGAAGGAGCCGAGGACTTCATGACGCCGCGTGACATCGTTCACCT GGCGACCGCATTGCTGCTTGACCCGGATGATGCCCTGTTTGAGGCCAGCCCAGGTTTGATTCGTACCCTGTATGACCCGA CCTGTGGCACGGGTGGCTTCCTCACCGATGCTATGAACCATGTGGGGGACTACGGTAACCGCGACAAGATCCCGCCAGTG CTGGTGCCGCACGGGCAGGAGTTGGAGCCGGAAACCCATGCGGTTTGTGTGGCCGGTATGCTGATCCGCCGTTTGGAGTC GGACCCTGGCCGAGATCTGTCGAAGAACATTCGTCAGGGCAGCACGCTGTCCAACGACCAGTTTGCCGGTGAGCGTTTCC ACTACTGCCTGTCCAATCCGCCTTTCGGCAAGAAATGGGAGAAGGACAAAACCGCTGTCGAAGCGGAACACAAAAAAGGC GAGCTGGGCCGGTTTGGTCCGGGCCTGCCGAAAATTAGCGATGGCTCCATGCTGTTTTTGATGCACCTGGCGAGCAAGCT AGAACTGCCGATCAACGGCGGTGGCCGCGCCGCTATTGTGCTGTCCGGTTCGCCACTGTTTAACGGCGGTGCCGCGTCTG GCGAATCGGAAATCCGCCGTTGGTTGCTGGAAGACGACCTGATTGAAGCCATTGTAGCTCTGCCAACGGATCTGTTCTTC CGCACCAATATCGCCACCTACCTGTGGATTCTGTCCAACAAGAAGCCTCAGGAGCGCAAAGGCAAGGTGCAGTTGATCAA CGCCACCGACCTGTGGACTTCAATCCGCAACGAGGGCAACAAGCGCCGTATTGTCAGCGATGAGCAGCGCCGCCAGATTC TGGACATCTACGCAGCAGGCGAAACCGGTGCGCTTTCCCGGATGCTGGACTACCGTACCTTTGGCTACCGCCGTATCAGG GTCCTGCGCCCGCTGCGCATGACCCTAGAGCTGGATAAGGTGGGTATGGAGCGGTTGGAAGCCGAAGCTGCCTGGGAAAA GCTCTCTGACGCGCATCAGACATTCTGGCGCGAAGCCCTCAAGCCGCTGATCGGGCAAACGCAGCCCTATAGCTGGGCAG AAACCTTTGTTAGCAACTCGATCAAGTCCGATGAAGCCAAGCAGCTCAAGGTCAAATCCAACAAGACATTGATCACCGCG CTAATCAACGCCTTTGGTCACAAAGACCCGAAAGCCGAGCCAGTCACGGATTCAAACGGCGAGCTGGTGCCAGACACAGA TTTAACTGATTACGAGAACGTCCCCTATCTGGAGGACATCGACGACTACTTTGCCCGCGAAGTGCTTCCTCATGTGCCGG ATGCCTGGCTGGATGAGAGCTTTACCGATGCCAGGGATGGTCAATTGGGCCGCGTTGGCTACGAGATCAACTTCAACCGC TTCTTCTACCAGTACCAGCCGCCGCGCAAGCTGCATGATATTGATGAAGACCTGAAGCAGGTAGAAGCCGAGATTGCCGC GCTACTGGCGGAGGTGGCCAGCGAATGA
Upstream 100 bases:
>100_bases TAGCCAAGAATTGAAATCCATCCCCTTTTGTGCAAAATCTGGTTGACATTCGCAGATTGACTACAGTACCATTCTGTGCA AAAGGTGGTTGGAGGCCAGA
Downstream 100 bases:
>100_bases GTCAGTACAAAGCGTATACCTCATACAAAGATTCAGGCGTTGAGTGGATTGGGCAGGTGCCGGAGCATTGGGAGGTGAAA AGGTTACGTCATGTCGGGCG
Product: DNA methylase M, host modification
Products: NA
Alternate protein names: M.MjaXP [H]
Number of amino acids: Translated: 675; Mature: 675
Protein sequence:
>675_residues MNEFTGSAASQADFIWKNAEDLWGDFKHTDFGKIILPFTLLRRLECALEPTREAVREAHDAFKDADVELDTILRSTAEYP FYNTSEYSLGTLGSTKTRRNLEDYIALFSDNARAIFEEFEFGNTVIRLEKAGLLYKICQNFAKIDLHPDVVPDRVMSNIY EHLIRRFGAEVNEGAEDFMTPRDIVHLATALLLDPDDALFEASPGLIRTLYDPTCGTGGFLTDAMNHVGDYGNRDKIPPV LVPHGQELEPETHAVCVAGMLIRRLESDPGRDLSKNIRQGSTLSNDQFAGERFHYCLSNPPFGKKWEKDKTAVEAEHKKG ELGRFGPGLPKISDGSMLFLMHLASKLELPINGGGRAAIVLSGSPLFNGGAASGESEIRRWLLEDDLIEAIVALPTDLFF RTNIATYLWILSNKKPQERKGKVQLINATDLWTSIRNEGNKRRIVSDEQRRQILDIYAAGETGALSRMLDYRTFGYRRIR VLRPLRMTLELDKVGMERLEAEAAWEKLSDAHQTFWREALKPLIGQTQPYSWAETFVSNSIKSDEAKQLKVKSNKTLITA LINAFGHKDPKAEPVTDSNGELVPDTDLTDYENVPYLEDIDDYFAREVLPHVPDAWLDESFTDARDGQLGRVGYEINFNR FFYQYQPPRKLHDIDEDLKQVEAEIAALLAEVASE
Sequences:
>Translated_675_residues MNEFTGSAASQADFIWKNAEDLWGDFKHTDFGKIILPFTLLRRLECALEPTREAVREAHDAFKDADVELDTILRSTAEYP FYNTSEYSLGTLGSTKTRRNLEDYIALFSDNARAIFEEFEFGNTVIRLEKAGLLYKICQNFAKIDLHPDVVPDRVMSNIY EHLIRRFGAEVNEGAEDFMTPRDIVHLATALLLDPDDALFEASPGLIRTLYDPTCGTGGFLTDAMNHVGDYGNRDKIPPV LVPHGQELEPETHAVCVAGMLIRRLESDPGRDLSKNIRQGSTLSNDQFAGERFHYCLSNPPFGKKWEKDKTAVEAEHKKG ELGRFGPGLPKISDGSMLFLMHLASKLELPINGGGRAAIVLSGSPLFNGGAASGESEIRRWLLEDDLIEAIVALPTDLFF RTNIATYLWILSNKKPQERKGKVQLINATDLWTSIRNEGNKRRIVSDEQRRQILDIYAAGETGALSRMLDYRTFGYRRIR VLRPLRMTLELDKVGMERLEAEAAWEKLSDAHQTFWREALKPLIGQTQPYSWAETFVSNSIKSDEAKQLKVKSNKTLITA LINAFGHKDPKAEPVTDSNGELVPDTDLTDYENVPYLEDIDDYFAREVLPHVPDAWLDESFTDARDGQLGRVGYEINFNR FFYQYQPPRKLHDIDEDLKQVEAEIAALLAEVASE >Mature_675_residues MNEFTGSAASQADFIWKNAEDLWGDFKHTDFGKIILPFTLLRRLECALEPTREAVREAHDAFKDADVELDTILRSTAEYP FYNTSEYSLGTLGSTKTRRNLEDYIALFSDNARAIFEEFEFGNTVIRLEKAGLLYKICQNFAKIDLHPDVVPDRVMSNIY EHLIRRFGAEVNEGAEDFMTPRDIVHLATALLLDPDDALFEASPGLIRTLYDPTCGTGGFLTDAMNHVGDYGNRDKIPPV LVPHGQELEPETHAVCVAGMLIRRLESDPGRDLSKNIRQGSTLSNDQFAGERFHYCLSNPPFGKKWEKDKTAVEAEHKKG ELGRFGPGLPKISDGSMLFLMHLASKLELPINGGGRAAIVLSGSPLFNGGAASGESEIRRWLLEDDLIEAIVALPTDLFF RTNIATYLWILSNKKPQERKGKVQLINATDLWTSIRNEGNKRRIVSDEQRRQILDIYAAGETGALSRMLDYRTFGYRRIR VLRPLRMTLELDKVGMERLEAEAAWEKLSDAHQTFWREALKPLIGQTQPYSWAETFVSNSIKSDEAKQLKVKSNKTLITA LINAFGHKDPKAEPVTDSNGELVPDTDLTDYENVPYLEDIDDYFAREVLPHVPDAWLDESFTDARDGQLGRVGYEINFNR FFYQYQPPRKLHDIDEDLKQVEAEIAALLAEVASE
Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]
COG id: COG0286
COG function: function code V; Type I restriction-modification system methyltransferase subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]
Homologues:
Organism=Escherichia coli, GI1790808, Length=321, Percent_Identity=25.5451713395639, Blast_Score=82, Evalue=2e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR022749 - InterPro: IPR003356 - InterPro: IPR002052 - InterPro: IPR002296 [H]
Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]
EC number: =2.1.1.72 [H]
Molecular weight: Translated: 76291; Mature: 76291
Theoretical pI: Translated: 4.84; Mature: 4.84
Prosite motif: PS00092 N6_MTASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNEFTGSAASQADFIWKNAEDLWGDFKHTDFGKIILPFTLLRRLECALEPTREAVREAHD CCCCCCCCCCCHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH AFKDADVELDTILRSTAEYPFYNTSEYSLGTLGSTKTRRNLEDYIALFSDNARAIFEEFE HHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH FGNTVIRLEKAGLLYKICQNFAKIDLHPDVVPDRVMSNIYEHLIRRFGAEVNEGAEDFMT CCCEEEEEECCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCC PRDIVHLATALLLDPDDALFEASPGLIRTLYDPTCGTGGFLTDAMNHVGDYGNRDKIPPV HHHHHHHHHHHHCCCCHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCE LVPHGQELEPETHAVCVAGMLIRRLESDPGRDLSKNIRQGSTLSNDQFAGERFHYCLSNP ECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHCCCCC PFGKKWEKDKTAVEAEHKKGELGRFGPGLPKISDGSMLFLMHLASKLELPINGGGRAAIV CCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEE LSGSPLFNGGAASGESEIRRWLLEDDLIEAIVALPTDLFFRTNIATYLWILSNKKPQERK EECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEEECCCCCCCCC GKVQLINATDLWTSIRNEGNKRRIVSDEQRRQILDIYAAGETGALSRMLDYRTFGYRRIR CCEEEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHCHHHHH VLRPLRMTLELDKVGMERLEAEAAWEKLSDAHQTFWREALKPLIGQTQPYSWAETFVSNS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC IKSDEAKQLKVKSNKTLITALINAFGHKDPKAEPVTDSNGELVPDTDLTDYENVPYLEDI CCCCCHHHEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH DDYFAREVLPHVPDAWLDESFTDARDGQLGRVGYEINFNRFFYQYQPPRKLHDIDEDLKQ HHHHHHHHHCCCCCHHHCCCCCCCCCCCCCEEEEEEEEEEEEEEECCCHHHHHHHHHHHH VEAEIAALLAEVASE HHHHHHHHHHHHHCC >Mature Secondary Structure MNEFTGSAASQADFIWKNAEDLWGDFKHTDFGKIILPFTLLRRLECALEPTREAVREAHD CCCCCCCCCCCHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH AFKDADVELDTILRSTAEYPFYNTSEYSLGTLGSTKTRRNLEDYIALFSDNARAIFEEFE HHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH FGNTVIRLEKAGLLYKICQNFAKIDLHPDVVPDRVMSNIYEHLIRRFGAEVNEGAEDFMT CCCEEEEEECCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCC PRDIVHLATALLLDPDDALFEASPGLIRTLYDPTCGTGGFLTDAMNHVGDYGNRDKIPPV HHHHHHHHHHHHCCCCHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCE LVPHGQELEPETHAVCVAGMLIRRLESDPGRDLSKNIRQGSTLSNDQFAGERFHYCLSNP ECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHCCCCC PFGKKWEKDKTAVEAEHKKGELGRFGPGLPKISDGSMLFLMHLASKLELPINGGGRAAIV CCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEE LSGSPLFNGGAASGESEIRRWLLEDDLIEAIVALPTDLFFRTNIATYLWILSNKKPQERK EECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEEECCCCCCCCC GKVQLINATDLWTSIRNEGNKRRIVSDEQRRQILDIYAAGETGALSRMLDYRTFGYRRIR CCEEEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHCHHHHH VLRPLRMTLELDKVGMERLEAEAAWEKLSDAHQTFWREALKPLIGQTQPYSWAETFVSNS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC IKSDEAKQLKVKSNKTLITALINAFGHKDPKAEPVTDSNGELVPDTDLTDYENVPYLEDI CCCCCHHHEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH DDYFAREVLPHVPDAWLDESFTDARDGQLGRVGYEINFNRFFYQYQPPRKLHDIDEDLKQ HHHHHHHHHCCCCCHHHCCCCCCCCCCCCCEEEEEEEEEEEEEEECCCHHHHHHHHHHHH VEAEIAALLAEVASE HHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8688087 [H]