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The map label for this gene is kdsB

Identifier: 152969502

GI number: 152969502

Start: 1065295

End: 1066041

Strand: Direct

Name: kdsB

Synonym: KPN_00945

Alternate gene names: 152969502

Gene position: 1065295-1066041 (Clockwise)

Preceding gene: 152969501

Following gene: 152969503

Centisome position: 20.04

GC content: 61.31

Gene sequence:

>747_bases
ATGAGTTTCGTGGTCATTATTCCTGCGCGTTTCGCCTCCACGCGCCTGCCGGGAAAACCACTGCAGGACATTAATGGTAA
GCCGATGATTGTCCATGTGCTGGAGCGCGCTCGCGAATCCGGCGCGGATCGCATTATTGTCGCCACCGATCACGAAGATG
TCGCCCGGGCGGTTGAAGCCGCCGGCGGCGAGGTCTGTATGACCCGCGCCGACCATCAGTCCGGCACCGAACGGCTGGCG
GAAGTGGTGGAAAAGTGCGCGTTCAGCGATGACACCATTATCGTCAATATTCAGGGCGATGAGCCGATGATCCCCCCGGC
GATTGTCCGCCAGGTGGCGGAGAATCTGGCTGCCAGCAGCAGCGGAATGGCGACGCTGGCGGTACCGATCCATGATGCGG
AAGAGGCGTTTAACCCGAATGCGGTCAAAGTGGTGATGGATGCCAAGGGTTACGCGCTCTATTTCTCCCGCGCGACTATT
CCCTGGGATCGCGATCGCTTTGCCCAATCCCGCGAGACCATCGGTGACTCCCTGCTGCGTCACATCGGCATCTATGGCTA
TCGCGCCGGCTTTATCCGCCGCTATGTCAGCTGGGCGCCGAGCCCGCTGGAGCAGATTGAAATGCTCGAGCAGCTGCGAG
TGCTGTGGTATGGCGAGAAAATCCATGTCGCCGTGGCGGCGGAAGTGCCCGGCACCGGCGTGGATACCCCGGAAGATCTG
GAGCGCGTCCGCGCTGAGCTGCGTTAG

Upstream 100 bases:

>100_bases
TTATTTGCAAACTTGATAGCCTGGCGTTTCCGCTGCGCGACGGTATCCCGGTGCTGCTGGAGACAGAGGCGCGTCCGCTG
GCGCTAGAAGAGAGTCACTC

Downstream 100 bases:

>100_bases
TCCTCTGTCCCCTCCTTGCTGGAGGGGATATCCCCGTCGGTTTTTCGCTTTTTTTACCCCTTTTTGATCTTATCCGATGA
CAACCCAGGTGCGGGCGCTC

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MSFVVIIPARFASTRLPGKPLQDINGKPMIVHVLERARESGADRIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLA
EVVEKCAFSDDTIIVNIQGDEPMIPPAIVRQVAENLAASSSGMATLAVPIHDAEEAFNPNAVKVVMDAKGYALYFSRATI
PWDRDRFAQSRETIGDSLLRHIGIYGYRAGFIRRYVSWAPSPLEQIEMLEQLRVLWYGEKIHVAVAAEVPGTGVDTPEDL
ERVRAELR

Sequences:

>Translated_248_residues
MSFVVIIPARFASTRLPGKPLQDINGKPMIVHVLERARESGADRIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLA
EVVEKCAFSDDTIIVNIQGDEPMIPPAIVRQVAENLAASSSGMATLAVPIHDAEEAFNPNAVKVVMDAKGYALYFSRATI
PWDRDRFAQSRETIGDSLLRHIGIYGYRAGFIRRYVSWAPSPLEQIEMLEQLRVLWYGEKIHVAVAAEVPGTGVDTPEDL
ERVRAELR
>Mature_247_residues
SFVVIIPARFASTRLPGKPLQDINGKPMIVHVLERARESGADRIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAE
VVEKCAFSDDTIIVNIQGDEPMIPPAIVRQVAENLAASSSGMATLAVPIHDAEEAFNPNAVKVVMDAKGYALYFSRATIP
WDRDRFAQSRETIGDSLLRHIGIYGYRAGFIRRYVSWAPSPLEQIEMLEQLRVLWYGEKIHVAVAAEVPGTGVDTPEDLE
RVRAELR

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=248, Percent_Identity=88.7096774193548, Blast_Score=461, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_KLEP7 (A6T710)

Other databases:

- EMBL:   CP000647
- RefSeq:   YP_001334611.1
- ProteinModelPortal:   A6T710
- SMR:   A6T710
- STRING:   A6T710
- GeneID:   5339799
- GenomeReviews:   CP000647_GR
- KEGG:   kpn:KPN_00945
- eggNOG:   COG1212
- HOGENOM:   HBG637773
- OMA:   FSRAPLP
- ProtClustDB:   PRK05450
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 27333; Mature: 27202

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVVIIPARFASTRLPGKPLQDINGKPMIVHVLERARESGADRIIVATDHEDVARAVEA
CCEEEEECCCHHCCCCCCCCHHCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHH
AGGEVCMTRADHQSGTERLAEVVEKCAFSDDTIIVNIQGDEPMIPPAIVRQVAENLAASS
CCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCC
SGMATLAVPIHDAEEAFNPNAVKVVMDAKGYALYFSRATIPWDRDRFAQSRETIGDSLLR
CCCEEEEEEECCHHHHCCCCEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
HIGIYGYRAGFIRRYVSWAPSPLEQIEMLEQLRVLWYGEKIHVAVAAEVPGTGVDTPEDL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHH
ERVRAELR
HHHHHHCC
>Mature Secondary Structure 
SFVVIIPARFASTRLPGKPLQDINGKPMIVHVLERARESGADRIIVATDHEDVARAVEA
CEEEEECCCHHCCCCCCCCHHCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHH
AGGEVCMTRADHQSGTERLAEVVEKCAFSDDTIIVNIQGDEPMIPPAIVRQVAENLAASS
CCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCC
SGMATLAVPIHDAEEAFNPNAVKVVMDAKGYALYFSRATIPWDRDRFAQSRETIGDSLLR
CCCEEEEEEECCHHHHCCCCEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
HIGIYGYRAGFIRRYVSWAPSPLEQIEMLEQLRVLWYGEKIHVAVAAEVPGTGVDTPEDL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHH
ERVRAELR
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA