Click here to switch to the map view.

The map label for this gene is dacC [H]

Identifier: 152969428

GI number: 152969428

Start: 977437

End: 978639

Strand: Direct

Name: dacC [H]

Synonym: KPN_00871

Alternate gene names: 152969428

Gene position: 977437-978639 (Clockwise)

Preceding gene: 152969426

Following gene: 152969431

Centisome position: 18.39

GC content: 56.53

Gene sequence:

>1203_bases
ATGATGCATGACGCTTTTTCCCTTCGCGGCCTCGCGGCAGGTTGCGCGCTGTTATTTCTTGTCGCACCTGCGGTGCAGGC
TGCGGAACAACTCCCCGACGCCCCTTCAATTGACGCTCGCGCCTGGATCCTGATGGACTATGCCAGCGGGAAGGTGCTCA
GCGAAGGCAATGCCGATGAAAAACTCGACCCGGCCAGTCTGACGAAGATCATGACCAGCTACGTGGTAGGGCAGGCAATA
AAAGCGGGAAAAATCAAACTGACCGATATGGTGACCGTTGGGCGCGATGCCTGGGCGACCGGCAACCCGGCGCTGCGCGG
CTCATCGGTGATGTTCCTCAAGCCTGGCATGCAGGTTTCCGTAGAAGATCTGAACAAAGGGGTCATCATTCAGTCCGGTA
ACGACGCCAGCATTGCGATTGCTGACTACGTAGCGGGCAGCCAGGACGCTTTCGTTAGCCTGATGAACGGCTACGCCAAA
AAAATGGGGCTGACCAACACCACCTTTATGACCGTCCACGGCCTTGACGCGCCGGGGCAGTTCAGCACCGCCCGCGATAT
GGCGCTGCTGACCAAAGCGATGATCCACGACGTACCGGAAGAGTATGCGGTACATAAAGAGAAAGAGTTCACTTTCAATA
AAATTCGCCAGCCGAACCGCAACCGCCTGCTGTGGAGCAGCAACCTCAACGCCGATGGCGTGAAAACCGGGACCACCGCC
GGGGCCGGCTATAACCTCGTCTCCTCGGCCACTCAGGGTGATATGCGTTTGATTGCCGTGGTGCTGGGGACCAAAACCGA
CCGCATTCGCTTTAACGAGTCAGAAAAACTGCTGACCTGGGGCTTCCGCTTCTTTGAAACCGTGACGCCGATTAAACCAG
ATGCCACCTTCGTTACCCAGCGCGTGTGGTTTGGCGATAGCAATGAAGCGAAACTGGGGGCTGGCGAGGCGGGCTCTATC
ACTTTGCCGAAGGGCCAGCTGAAAAACCTGAAAGCCAGCTATACCTTAAATCAGCCACAGCTTACCGCGCCGCTGGAGAA
GGGGCAGGTGGTCGGGACTATCGACTTTAAGCTAAATGATAAAACCATTGAACAGCGTCCGCTGATTGTCATGGAGTCGG
TAAAAGAGGGCGGCTTCTTCAGCCGGATGATCGACTTCGTGCTGATGAAACTGCACGGCTGGTTCGGTAGCTGGTTCTCC
TGA

Upstream 100 bases:

>100_bases
GTTTCTTTAAGGTCATTTGTACGCTTTACTCACCGGTTGCTGCGGCGCGGTCAGAGTGGCGCGGCATATTTTGTTTGGAA
AGGATACTTGGGTGGCTCTT

Downstream 100 bases:

>100_bases
TGCCTGCCCGCGCCCTGCGGGGCGCGGGCAGCGACGCTTCAATACAGTAGGGAAATCTGCTGCGCCTTCGCCAGCGCGAC
CAGCTCATCATCCGGGCAGA

Product: D-alanyl-D-alanine carboxypeptidase fraction C

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MMHDAFSLRGLAAGCALLFLVAPAVQAAEQLPDAPSIDARAWILMDYASGKVLSEGNADEKLDPASLTKIMTSYVVGQAI
KAGKIKLTDMVTVGRDAWATGNPALRGSSVMFLKPGMQVSVEDLNKGVIIQSGNDASIAIADYVAGSQDAFVSLMNGYAK
KMGLTNTTFMTVHGLDAPGQFSTARDMALLTKAMIHDVPEEYAVHKEKEFTFNKIRQPNRNRLLWSSNLNADGVKTGTTA
GAGYNLVSSATQGDMRLIAVVLGTKTDRIRFNESEKLLTWGFRFFETVTPIKPDATFVTQRVWFGDSNEAKLGAGEAGSI
TLPKGQLKNLKASYTLNQPQLTAPLEKGQVVGTIDFKLNDKTIEQRPLIVMESVKEGGFFSRMIDFVLMKLHGWFGSWFS

Sequences:

>Translated_400_residues
MMHDAFSLRGLAAGCALLFLVAPAVQAAEQLPDAPSIDARAWILMDYASGKVLSEGNADEKLDPASLTKIMTSYVVGQAI
KAGKIKLTDMVTVGRDAWATGNPALRGSSVMFLKPGMQVSVEDLNKGVIIQSGNDASIAIADYVAGSQDAFVSLMNGYAK
KMGLTNTTFMTVHGLDAPGQFSTARDMALLTKAMIHDVPEEYAVHKEKEFTFNKIRQPNRNRLLWSSNLNADGVKTGTTA
GAGYNLVSSATQGDMRLIAVVLGTKTDRIRFNESEKLLTWGFRFFETVTPIKPDATFVTQRVWFGDSNEAKLGAGEAGSI
TLPKGQLKNLKASYTLNQPQLTAPLEKGQVVGTIDFKLNDKTIEQRPLIVMESVKEGGFFSRMIDFVLMKLHGWFGSWFS
>Mature_400_residues
MMHDAFSLRGLAAGCALLFLVAPAVQAAEQLPDAPSIDARAWILMDYASGKVLSEGNADEKLDPASLTKIMTSYVVGQAI
KAGKIKLTDMVTVGRDAWATGNPALRGSSVMFLKPGMQVSVEDLNKGVIIQSGNDASIAIADYVAGSQDAFVSLMNGYAK
KMGLTNTTFMTVHGLDAPGQFSTARDMALLTKAMIHDVPEEYAVHKEKEFTFNKIRQPNRNRLLWSSNLNADGVKTGTTA
GAGYNLVSSATQGDMRLIAVVLGTKTDRIRFNESEKLLTWGFRFFETVTPIKPDATFVTQRVWFGDSNEAKLGAGEAGSI
TLPKGQLKNLKASYTLNQPQLTAPLEKGQVVGTIDFKLNDKTIEQRPLIVMESVKEGGFFSRMIDFVLMKLHGWFGSWFS

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=393, Percent_Identity=86.5139949109415, Blast_Score=712, Evalue=0.0,
Organism=Escherichia coli, GI1786851, Length=366, Percent_Identity=62.2950819672131, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI87082022, Length=385, Percent_Identity=47.7922077922078, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI87082054, Length=251, Percent_Identity=26.2948207171315, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 43491; Mature: 43491

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHDAFSLRGLAAGCALLFLVAPAVQAAEQLPDAPSIDARAWILMDYASGKVLSEGNADE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEECCCCCC
KLDPASLTKIMTSYVVGQAIKAGKIKLTDMVTVGRDAWATGNPALRGSSVMFLKPGMQVS
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEE
VEDLNKGVIIQSGNDASIAIADYVAGSQDAFVSLMNGYAKKMGLTNTTFMTVHGLDAPGQ
HHHCCCCEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCC
FSTARDMALLTKAMIHDVPEEYAVHKEKEFTFNKIRQPNRNRLLWSSNLNADGVKTGTTA
CCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHCCCCCCEEEEECCCCCCCCCCCCCC
GAGYNLVSSATQGDMRLIAVVLGTKTDRIRFNESEKLLTWGFRFFETVTPIKPDATFVTQ
CCCCHHHHCCCCCCEEEEEEEECCCCCEEEECCCCCEEHHHHHHHHHCCCCCCCCCEEEE
RVWFGDSNEAKLGAGEAGSITLPKGQLKNLKASYTLNQPQLTAPLEKGQVVGTIDFKLND
EEEECCCCCCEECCCCCCEEECCCHHHHCCEEEEEECCCCEECCCCCCCEEEEEEEEECC
KTIEQRPLIVMESVKEGGFFSRMIDFVLMKLHGWFGSWFS
CCCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMHDAFSLRGLAAGCALLFLVAPAVQAAEQLPDAPSIDARAWILMDYASGKVLSEGNADE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEECCCCCC
KLDPASLTKIMTSYVVGQAIKAGKIKLTDMVTVGRDAWATGNPALRGSSVMFLKPGMQVS
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEE
VEDLNKGVIIQSGNDASIAIADYVAGSQDAFVSLMNGYAKKMGLTNTTFMTVHGLDAPGQ
HHHCCCCEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCC
FSTARDMALLTKAMIHDVPEEYAVHKEKEFTFNKIRQPNRNRLLWSSNLNADGVKTGTTA
CCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHCCCCCCEEEEECCCCCCCCCCCCCC
GAGYNLVSSATQGDMRLIAVVLGTKTDRIRFNESEKLLTWGFRFFETVTPIKPDATFVTQ
CCCCHHHHCCCCCCEEEEEEEECCCCCEEEECCCCCEEHHHHHHHHHCCCCCCCCCEEEE
RVWFGDSNEAKLGAGEAGSITLPKGQLKNLKASYTLNQPQLTAPLEKGQVVGTIDFKLND
EEEECCCCCCEECCCCCCEEECCCHHHHCCEEEEEECCCCEECCCCCCCEEEEEEEEECC
KTIEQRPLIVMESVKEGGFFSRMIDFVLMKLHGWFGSWFS
CCCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]