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The map label for this gene is mnaA

Identifier: 151222227

GI number: 151222227

Start: 2232165

End: 2233295

Strand: Reverse

Name: mnaA

Synonym: NWMN_2015

Alternate gene names: 151222227

Gene position: 2233295-2232165 (Counterclockwise)

Preceding gene: 151222228

Following gene: 151222226

Centisome position: 77.57

GC content: 34.57

Gene sequence:

>1131_bases
TTGATGAAAAAGATTATGACCATATTTGGAACAAGACCCGAAGCCATAAAGATGGCTCCTTTAGTTAAAGCTTTGGAACA
AGAAAAAATGCTCGAGCCAATTGTTGTTGTTACAGCACAGCATAGAGAAATGCTTGATTCAGTATTAAGTACCTTTGAAA
TCAAACCAAAATACGATTTGAATATTATGAAATCAGGACAGACACTTTCTGAGATAACTTCTAAATCAATCACTCAATTA
GAACAAGTGATTCAATTAGAAAAACCAGACATGGTACTTGTACATGGTGATACGATGACGACATTTGCAGGTGGTTTAGC
GGCATTTTATAACCAAGTGCCGATTGGACACGTTGAAGCAGGGCTTAGAAGTTATGATAAATATTCACCTTTTCCAGAAG
AGGTGAATAGACAATTAGTTGGTGTATTAGCTGACTTACATTTTGCACCTACTAAAAATGCTGCATCGCATTTGTTAAGT
GAAGGGAAATATTCAGAAAGTGTTGTTGTCACTGGTAATACTGCGATTGATGCTATGAAATATACAGTTGATGACAATTA
TAAATCTAACATCATGGATAAATACCATGACAAAAAATTCATTCTTATGACAGCACACCGACGAGAAAATATCGGGAAAC
CCATGGAAAATATATTTAAAGCGGTTAGACGCTTAATAGATGAGTATACTGATTTAGCACTGGTATATCCAATGCATAAA
AACCCGAAAGTTCGAGAGGTGGCTCAAAAGATTTTAGGTAGTCATGACAGAATTGAATTGATTGAACCTTTGGACGTAGT
AGATTTCCATAATTTTGCTAAAAAATCTTATTTTATTTTGACAGATTCAGGTGGAATTCAGGAAGAAGCGCCATCATTTA
ATAAGCCAGTTTTAGTTTTGCGAAGTGTTACAGAACGTCCTGAAGGTGTTGAAGCTGGCACATTAAAAGTCATTGGAACA
AATAAGCAAAATGTGTATCAAGCTGCAAAAGAATTAATCGATGATGAGAGATTATATCATCAAATGTCTGAAGCATCTAA
TCCTTACGGTGATGGATTTGCTTCAGAAAGAATAGTTAATCATATTAAGTATTATTTGAATTTAATCACTGAAAAACCAA
GCGATTTCTGA

Upstream 100 bases:

>100_bases
TTGATGAAAAGCTAAATGACAAAGCATATATCACACCAGGGTTAGGCGACGCTGGAGATAGATTGTTTGGTACTAAATAG
AAGAATCGGAGATAAGTAGT

Downstream 100 bases:

>100_bases
GGAAAATAGACTTTTTGTCTAATTGTGTCTAAATTGTGTCTAACTATGCTTATTTTTTTACAACAATTTGAATAGAATTG
ACACCACAAATCGCCTATAT

Product: UDP-GlcNAc 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MMKKIMTIFGTRPEAIKMAPLVKALEQEKMLEPIVVVTAQHREMLDSVLSTFEIKPKYDLNIMKSGQTLSEITSKSITQL
EQVIQLEKPDMVLVHGDTMTTFAGGLAAFYNQVPIGHVEAGLRSYDKYSPFPEEVNRQLVGVLADLHFAPTKNAASHLLS
EGKYSESVVVTGNTAIDAMKYTVDDNYKSNIMDKYHDKKFILMTAHRRENIGKPMENIFKAVRRLIDEYTDLALVYPMHK
NPKVREVAQKILGSHDRIELIEPLDVVDFHNFAKKSYFILTDSGGIQEEAPSFNKPVLVLRSVTERPEGVEAGTLKVIGT
NKQNVYQAAKELIDDERLYHQMSEASNPYGDGFASERIVNHIKYYLNLITEKPSDF

Sequences:

>Translated_376_residues
MMKKIMTIFGTRPEAIKMAPLVKALEQEKMLEPIVVVTAQHREMLDSVLSTFEIKPKYDLNIMKSGQTLSEITSKSITQL
EQVIQLEKPDMVLVHGDTMTTFAGGLAAFYNQVPIGHVEAGLRSYDKYSPFPEEVNRQLVGVLADLHFAPTKNAASHLLS
EGKYSESVVVTGNTAIDAMKYTVDDNYKSNIMDKYHDKKFILMTAHRRENIGKPMENIFKAVRRLIDEYTDLALVYPMHK
NPKVREVAQKILGSHDRIELIEPLDVVDFHNFAKKSYFILTDSGGIQEEAPSFNKPVLVLRSVTERPEGVEAGTLKVIGT
NKQNVYQAAKELIDDERLYHQMSEASNPYGDGFASERIVNHIKYYLNLITEKPSDF
>Mature_376_residues
MMKKIMTIFGTRPEAIKMAPLVKALEQEKMLEPIVVVTAQHREMLDSVLSTFEIKPKYDLNIMKSGQTLSEITSKSITQL
EQVIQLEKPDMVLVHGDTMTTFAGGLAAFYNQVPIGHVEAGLRSYDKYSPFPEEVNRQLVGVLADLHFAPTKNAASHLLS
EGKYSESVVVTGNTAIDAMKYTVDDNYKSNIMDKYHDKKFILMTAHRRENIGKPMENIFKAVRRLIDEYTDLALVYPMHK
NPKVREVAQKILGSHDRIELIEPLDVVDFHNFAKKSYFILTDSGGIQEEAPSFNKPVLVLRSVTERPEGVEAGTLKVIGT
NKQNVYQAAKELIDDERLYHQMSEASNPYGDGFASERIVNHIKYYLNLITEKPSDF

Specific function: Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine, a precursor of the teichoic acid linkage unit [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=369, Percent_Identity=50.6775067750677, Blast_Score=358, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 42544; Mature: 42544

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKIMTIFGTRPEAIKMAPLVKALEQEKMLEPIVVVTAQHREMLDSVLSTFEIKPKYDL
CHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHEECCCCCCC
NIMKSGQTLSEITSKSITQLEQVIQLEKPDMVLVHGDTMTTFAGGLAAFYNQVPIGHVEA
EEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHH
GLRSYDKYSPFPEEVNRQLVGVLADLHFAPTKNAASHLLSEGKYSESVVVTGNTAIDAMK
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHEE
YTVDDNYKSNIMDKYHDKKFILMTAHRRENIGKPMENIFKAVRRLIDEYTDLALVYPMHK
EEECCCHHHHHHHHHCCCEEEEEECHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCC
NPKVREVAQKILGSHDRIELIEPLDVVDFHNFAKKSYFILTDSGGIQEEAPSFNKPVLVL
CCCHHHHHHHHHCCCCCEEHCCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEEEE
RSVTERPEGVEAGTLKVIGTNKQNVYQAAKELIDDERLYHQMSEASNPYGDGFASERIVN
EHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
HIKYYLNLITEKPSDF
HHHHHHHHHHCCCCCC
>Mature Secondary Structure
MMKKIMTIFGTRPEAIKMAPLVKALEQEKMLEPIVVVTAQHREMLDSVLSTFEIKPKYDL
CHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHEECCCCCCC
NIMKSGQTLSEITSKSITQLEQVIQLEKPDMVLVHGDTMTTFAGGLAAFYNQVPIGHVEA
EEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHH
GLRSYDKYSPFPEEVNRQLVGVLADLHFAPTKNAASHLLSEGKYSESVVVTGNTAIDAMK
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHEE
YTVDDNYKSNIMDKYHDKKFILMTAHRRENIGKPMENIFKAVRRLIDEYTDLALVYPMHK
EEECCCHHHHHHHHHCCCEEEEEECHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCC
NPKVREVAQKILGSHDRIELIEPLDVVDFHNFAKKSYFILTDSGGIQEEAPSFNKPVLVL
CCCHHHHHHHHHCCCCCEEHCCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEEEE
RSVTERPEGVEAGTLKVIGTNKQNVYQAAKELIDDERLYHQMSEASNPYGDGFASERIVN
EHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
HIKYYLNLITEKPSDF
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8126437; 12107153; 9384377 [H]