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The map label for this gene is 150398630

Identifier: 150398630

GI number: 150398630

Start: 3651152

End: 3652870

Strand: Direct

Name: 150398630

Synonym: Smed_3444

Alternate gene names: NA

Gene position: 3651152-3652870 (Clockwise)

Preceding gene: 150398629

Following gene: 150398631

Centisome position: 96.54

GC content: 62.48

Gene sequence:

>1719_bases
ATGGTTGAAGCGTCAGAGAAGAGCCGGGAAGATGCTTCGTCCGGCAGCCTGCAGGCTGCCGCCGGTTTTGTCCGCGACTA
TCTTCGCCGACCGTTCAGCTTTTATCTGATCTCGCTGCTGCTCATTGCCATCATACCGCCCTTCATTTTTTCCTTTGTGA
TCCTGCAGCGCAATTTGGACGCGCAGAGAGAGGAGGTCACCTCTCTGCTGCGAGCCTCGACCGGATCGGTCACACGGATC
GTCGAGCGTGAAGTCGACGGCATGCTGACGACGCTCCGGGTGCTGGCGAAATCCGGCGCGGTGGATCTCGCCGATATGCA
AGGACTATACGAGCGGGCGTCGGTCGCGTTGGCGGACACCGATTCCCACCTGATCATCGTCGACAGCAAGCACGATCTCC
TTCTGAGTACCCGCGTTGCCTTCGGCACGCCGCTGGGGCGTGCGTCGGATCCGGAAGTCGAGCTCGCCTTGCAAAGTACG
GCCCCGCTCGTTTCGGGCGTATTCCCCGCCGAAATGGGAAAGGGCTGGGTGTTCACGGTCTATCTTCCGGTGACGACGCC
TGACGGAAAAAAATATCTGCTGGGGCTGAGGCAGGACGCCGAGCGAATGACGAGGGCCGTCAATCGCGATACGCTCTCGC
CGGGGTGGAATGCCGCGCTCGTCGACGGCAAGGGCAGGGTGATCGTTTCCTCGGACGCGGCGGTGAAATCCGGCGATCCG
TTCTTCCTCGATGAATTGCCGTTGATCAGCATCGGTGTCAGCAATATCAGCGCCCGCGGCGTCGACTATCGCGTCGCGTC
GGAGTTTTCAGTGGTGACCGGCTGGCGCATCGTCGCCTGGGCACCGAGTGAGATCGTCGATCAGCCGATGCTCTGGTCGT
TCGTCTGGCTCTCCTTCGGTGGGATCATCTTTGCAAGCATCGCGGTCGCCGGTTCTTTGACCATTGCGCGGCTGCTAACA
CAGGGCGTCCGCTTACTGGCAATGGATGCCCGGCGGCTGGGCGCGGGCGAGCCCGTCGAACCGCGCCGTTACGTGATCAC
CGAAGTCGAAGCGGTGTCCACCGCCCTCGCAAGCGCTGCGACCGCCCGCACCAAAGCCGAAAGTGAAATCCGTCTCCTGA
TGCGGGAGGTTGCGCATCGGGCGAAGAATCAGCTCACCGTCATCCAGTCCATGCTGGCGCAGTCGGCCAACTCGGCGGAG
GATCCTTCGGATTTCGTGGAGGCGTTCAGAAAGCGTCTTGCCGGCCTTGCACGCTCGACCGACCTTATGGTGGCGAATGC
GGCCAACGGAGTGGATTTCAGCGAGCTCGTGCGCAACCAGCTTCAGCCGTTCATGCCGGCCGAATCCGATCGTGTCGTGC
TCAGCGGACCCGTCCTGCGGCTGGACTCGCAGATGGCGCAGACCCTCGGTATGGCGCTGCATGAACTGGCCACCAATGCC
ATCAAGCATGGAGCGCTCGCCAACCAGACCGGCATGATCAGGATTGCCTGGACGGTGTCGGACGGGGCGATCGAAATCAG
CTGGCGCGAGAGCGGCGCCGATATTGTCGCGCCTTCAGGGCAAAAGTCTCGCAGGGGGTTCGGTACGGTCGTGCTGGAGC
GCATGCTCGGCATGGCGCTGCGTGCCGAGCTCGAACGGACCATGCATGCCGATGGCATCGAATGGCGGATACGCATTCCC
CGCGACGAGGATGCCGCCGCGCGTGAGGCAGACAGTTGA

Upstream 100 bases:

>100_bases
CCCGCAAGCCGCGCGCGGGAAAAAGATTCGGGCGGCAGGCTTGAGGCACACGGCATGCCGTTTCGATGGAAGCGGCAGAG
ATGGGCAAGAGGCGGTACCT

Downstream 100 bases:

>100_bases
GGGGCAGTTCGCCGCCTGGAAAACCACCTGAAATGGCGCCGTGGCATCCGCCCGCAATCGAAAGTCACGTCAGGCCGGGG
GCGGCCCCGCTCACGCGGTT

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 572; Mature: 572

Protein sequence:

>572_residues
MVEASEKSREDASSGSLQAAAGFVRDYLRRPFSFYLISLLLIAIIPPFIFSFVILQRNLDAQREEVTSLLRASTGSVTRI
VEREVDGMLTTLRVLAKSGAVDLADMQGLYERASVALADTDSHLIIVDSKHDLLLSTRVAFGTPLGRASDPEVELALQST
APLVSGVFPAEMGKGWVFTVYLPVTTPDGKKYLLGLRQDAERMTRAVNRDTLSPGWNAALVDGKGRVIVSSDAAVKSGDP
FFLDELPLISIGVSNISARGVDYRVASEFSVVTGWRIVAWAPSEIVDQPMLWSFVWLSFGGIIFASIAVAGSLTIARLLT
QGVRLLAMDARRLGAGEPVEPRRYVITEVEAVSTALASAATARTKAESEIRLLMREVAHRAKNQLTVIQSMLAQSANSAE
DPSDFVEAFRKRLAGLARSTDLMVANAANGVDFSELVRNQLQPFMPAESDRVVLSGPVLRLDSQMAQTLGMALHELATNA
IKHGALANQTGMIRIAWTVSDGAIEISWRESGADIVAPSGQKSRRGFGTVVLERMLGMALRAELERTMHADGIEWRIRIP
RDEDAAAREADS

Sequences:

>Translated_572_residues
MVEASEKSREDASSGSLQAAAGFVRDYLRRPFSFYLISLLLIAIIPPFIFSFVILQRNLDAQREEVTSLLRASTGSVTRI
VEREVDGMLTTLRVLAKSGAVDLADMQGLYERASVALADTDSHLIIVDSKHDLLLSTRVAFGTPLGRASDPEVELALQST
APLVSGVFPAEMGKGWVFTVYLPVTTPDGKKYLLGLRQDAERMTRAVNRDTLSPGWNAALVDGKGRVIVSSDAAVKSGDP
FFLDELPLISIGVSNISARGVDYRVASEFSVVTGWRIVAWAPSEIVDQPMLWSFVWLSFGGIIFASIAVAGSLTIARLLT
QGVRLLAMDARRLGAGEPVEPRRYVITEVEAVSTALASAATARTKAESEIRLLMREVAHRAKNQLTVIQSMLAQSANSAE
DPSDFVEAFRKRLAGLARSTDLMVANAANGVDFSELVRNQLQPFMPAESDRVVLSGPVLRLDSQMAQTLGMALHELATNA
IKHGALANQTGMIRIAWTVSDGAIEISWRESGADIVAPSGQKSRRGFGTVVLERMLGMALRAELERTMHADGIEWRIRIP
RDEDAAAREADS
>Mature_572_residues
MVEASEKSREDASSGSLQAAAGFVRDYLRRPFSFYLISLLLIAIIPPFIFSFVILQRNLDAQREEVTSLLRASTGSVTRI
VEREVDGMLTTLRVLAKSGAVDLADMQGLYERASVALADTDSHLIIVDSKHDLLLSTRVAFGTPLGRASDPEVELALQST
APLVSGVFPAEMGKGWVFTVYLPVTTPDGKKYLLGLRQDAERMTRAVNRDTLSPGWNAALVDGKGRVIVSSDAAVKSGDP
FFLDELPLISIGVSNISARGVDYRVASEFSVVTGWRIVAWAPSEIVDQPMLWSFVWLSFGGIIFASIAVAGSLTIARLLT
QGVRLLAMDARRLGAGEPVEPRRYVITEVEAVSTALASAATARTKAESEIRLLMREVAHRAKNQLTVIQSMLAQSANSAE
DPSDFVEAFRKRLAGLARSTDLMVANAANGVDFSELVRNQLQPFMPAESDRVVLSGPVLRLDSQMAQTLGMALHELATNA
IKHGALANQTGMIRIAWTVSDGAIEISWRESGADIVAPSGQKSRRGFGTVVLERMLGMALRAELERTMHADGIEWRIRIP
RDEDAAAREADS

Specific function: Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light. Once ejected from an infected animal host, sunlight acts as an environmental signal that increases the virulence of the bacterium, preparing it for infection o

COG id: COG3920

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR011102 [H]

Pfam domain/function: PF07536 HWE_HK; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62080; Mature: 62080

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEASEKSREDASSGSLQAAAGFVRDYLRRPFSFYLISLLLIAIIPPFIFSFVILQRNLD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AQREEVTSLLRASTGSVTRIVEREVDGMLTTLRVLAKSGAVDLADMQGLYERASVALADT
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCEEEEEC
DSHLIIVDSKHDLLLSTRVAFGTPLGRASDPEVELALQSTAPLVSGVFPAEMGKGWVFTV
CCEEEEEECCCCEEEEEHHHHCCCCCCCCCCCEEEEECCCCCHHHCCCHHHCCCCEEEEE
YLPVTTPDGKKYLLGLRQDAERMTRAVNRDTLSPGWNAALVDGKGRVIVSSDAAVKSGDP
EEEEECCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCC
FFLDELPLISIGVSNISARGVDYRVASEFSVVTGWRIVAWAPSEIVDQPMLWSFVWLSFG
CEECCCCEEEEECCCCCCCCCCEEECCCCEEEECCEEEEECCHHHHCCCHHHHHHHHHHH
GIIFASIAVAGSLTIARLLTQGVRLLAMDARRLGAGEPVEPRRYVITEVEAVSTALASAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEHHHHHHHHHHHHHH
TARTKAESEIRLLMREVAHRAKNQLTVIQSMLAQSANSAEDPSDFVEAFRKRLAGLARST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
DLMVANAANGVDFSELVRNQLQPFMPAESDRVVLSGPVLRLDSQMAQTLGMALHELATNA
CEEEEECCCCCCHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
IKHGALANQTGMIRIAWTVSDGAIEISWRESGADIVAPSGQKSRRGFGTVVLERMLGMAL
HHHCCCCCCCCEEEEEEEECCCEEEEEEECCCCCEECCCCCCCCCHHHHHHHHHHHHHHH
RAELERTMHADGIEWRIRIPRDEDAAAREADS
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MVEASEKSREDASSGSLQAAAGFVRDYLRRPFSFYLISLLLIAIIPPFIFSFVILQRNLD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AQREEVTSLLRASTGSVTRIVEREVDGMLTTLRVLAKSGAVDLADMQGLYERASVALADT
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCEEEEEC
DSHLIIVDSKHDLLLSTRVAFGTPLGRASDPEVELALQSTAPLVSGVFPAEMGKGWVFTV
CCEEEEEECCCCEEEEEHHHHCCCCCCCCCCCEEEEECCCCCHHHCCCHHHCCCCEEEEE
YLPVTTPDGKKYLLGLRQDAERMTRAVNRDTLSPGWNAALVDGKGRVIVSSDAAVKSGDP
EEEEECCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCC
FFLDELPLISIGVSNISARGVDYRVASEFSVVTGWRIVAWAPSEIVDQPMLWSFVWLSFG
CEECCCCEEEEECCCCCCCCCCEEECCCCEEEECCEEEEECCHHHHCCCHHHHHHHHHHH
GIIFASIAVAGSLTIARLLTQGVRLLAMDARRLGAGEPVEPRRYVITEVEAVSTALASAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEHHHHHHHHHHHHHH
TARTKAESEIRLLMREVAHRAKNQLTVIQSMLAQSANSAEDPSDFVEAFRKRLAGLARST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
DLMVANAANGVDFSELVRNQLQPFMPAESDRVVLSGPVLRLDSQMAQTLGMALHELATNA
CEEEEECCCCCCHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
IKHGALANQTGMIRIAWTVSDGAIEISWRESGADIVAPSGQKSRRGFGTVVLERMLGMAL
HHHCCCCCCCCEEEEEEEECCCEEEEEEECCCCCEECCCCCCCCCHHHHHHHHHHHHHHH
RAELERTMHADGIEWRIRIPRDEDAAAREADS
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA