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The map label for this gene is lolC [H]

Identifier: 150396142

GI number: 150396142

Start: 991351

End: 992661

Strand: Direct

Name: lolC [H]

Synonym: Smed_0919

Alternate gene names: 150396142

Gene position: 991351-992661 (Clockwise)

Preceding gene: 150396141

Following gene: 150396143

Centisome position: 26.21

GC content: 61.33

Gene sequence:

>1311_bases
ATGACTGCGGCGACGGACGAGCAAGTGCAGGCTGCCGCTCCATCCAGCATACCTTCCGGCCGTCCCTTCTCCGCTTTCGA
GCGTATGGTCGCCTGGCGCTACCTGCGTTCGCGGCGGAAGGAAGCCTTCATCTCGGTCATCGCCGGCTTTTCTTTCATCG
GGATCATGCTCGGGGTCGGAACGCTGATCATCGTCATGGCGGTGATGAACGGCTTCAGAACCGAGCTCATTTCACGCATT
CTCGGCATGAACGGCCATATGATCGTTCAACCGCTGGATGGACCGCTCACAAATTACGCCGATCTCGCCACCAGGTTTTC
CGCCGTTCCCGGCGTCACCATGGCCATTCCGATCGTCGAGGGCCAGGTTCTCGCGCAAGGCTTCGGGGATGCCTCGACGG
GTGCGCTCGTTCGCGGAATACGCGCTGACGACCTCACCAAGCTCAAGTCGGTCTCGGAAAAAATCCAGGCGGGCGACCTC
GTCGGTTTCGCTTCGGGCAGCGGCGTCGCCATCGGCTCGCGCATGGCCGAGCAATTGGGTATCCGCGTGGGCGGGACGAT
CACGCTCACCTCGCCGAACGGCGACGTGACGCCGATGGGCATGAATCCGAGGGTCAAGGGCTATACCGTTTCGGCCATAT
TCGAGATGGGCATGTCGGAATACGACGCGACCATCATCTTCATGCCGCTCGAGGAAGCACAGCTCTATTTCAACGCCGAG
GGCCTCGTCCAGTCGATCGAGCTTTTCGTCGAGCATCCGGATGCCGTCGACACGCTTCGCGAGCCGGTGGAGAAGGCGGC
CGGCCGGCAGATATTCATCACCGACTGGCGCGAACGGAACAGGACGTTCTTTTCCGCGCTCGAGGTGGAGCGGAACGTCA
TGTTCATGATCCTGACGCTCATCGTGCTGGTCGCGGCGCTGAATATCATCTCCGGCCTGATCATGCTGGTGAAGGATAAG
GGCAGTGACATCGCGATCCTCAGGACGATGGGGGCGACCTCCGGCTCGGTGATGCGAATCTTCTTCATGACCGGCGCAGC
CATAGGCGTCACGGGAACGATCGCCGGCGTCGTCCTCGGGGTCGTCGTCTGCCTGAATATCGAATCGATCCGCCAGTTCT
TCTCCTGGGTCTCGGGCGCCACGCTTTTCGATCCGGAGCTTTACTTCCTGAGTCAGCTTCCGGCTGACATGAATGCCGAC
GAGACTGTCACCGTCGTCATCATGGCGCTCGCGCTTTCCTTCCTTGCCACGATCTTCCCGGCCTGGCGCGCCTCGCGCCT
CGATCCGGTGCAGGCCCTGCGGTACGAATAA

Upstream 100 bases:

>100_bases
CGAAGTGAAGGACCGCAAGACCGGTGCGCGAGAGACGATGACAGTCGAAGCGGCGATCAACAAACTGGTCGCGGCGAGAT
AACAGGCGAAGGGATCAATG

Downstream 100 bases:

>100_bases
CAAGGACATCAGCATAAATGAATGCGCGCGTGGCACTGCAGCTCTCCGGCATCGAGCGGCATTATGGCGAGGGCGAAACC
TTCCTGCCGATCCTCAAGGG

Product: LolC/E family lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTAATDEQVQAAAPSSIPSGRPFSAFERMVAWRYLRSRRKEAFISVIAGFSFIGIMLGVGTLIIVMAVMNGFRTELISRI
LGMNGHMIVQPLDGPLTNYADLATRFSAVPGVTMAIPIVEGQVLAQGFGDASTGALVRGIRADDLTKLKSVSEKIQAGDL
VGFASGSGVAIGSRMAEQLGIRVGGTITLTSPNGDVTPMGMNPRVKGYTVSAIFEMGMSEYDATIIFMPLEEAQLYFNAE
GLVQSIELFVEHPDAVDTLREPVEKAAGRQIFITDWRERNRTFFSALEVERNVMFMILTLIVLVAALNIISGLIMLVKDK
GSDIAILRTMGATSGSVMRIFFMTGAAIGVTGTIAGVVLGVVVCLNIESIRQFFSWVSGATLFDPELYFLSQLPADMNAD
ETVTVVIMALALSFLATIFPAWRASRLDPVQALRYE

Sequences:

>Translated_436_residues
MTAATDEQVQAAAPSSIPSGRPFSAFERMVAWRYLRSRRKEAFISVIAGFSFIGIMLGVGTLIIVMAVMNGFRTELISRI
LGMNGHMIVQPLDGPLTNYADLATRFSAVPGVTMAIPIVEGQVLAQGFGDASTGALVRGIRADDLTKLKSVSEKIQAGDL
VGFASGSGVAIGSRMAEQLGIRVGGTITLTSPNGDVTPMGMNPRVKGYTVSAIFEMGMSEYDATIIFMPLEEAQLYFNAE
GLVQSIELFVEHPDAVDTLREPVEKAAGRQIFITDWRERNRTFFSALEVERNVMFMILTLIVLVAALNIISGLIMLVKDK
GSDIAILRTMGATSGSVMRIFFMTGAAIGVTGTIAGVVLGVVVCLNIESIRQFFSWVSGATLFDPELYFLSQLPADMNAD
ETVTVVIMALALSFLATIFPAWRASRLDPVQALRYE
>Mature_435_residues
TAATDEQVQAAAPSSIPSGRPFSAFERMVAWRYLRSRRKEAFISVIAGFSFIGIMLGVGTLIIVMAVMNGFRTELISRIL
GMNGHMIVQPLDGPLTNYADLATRFSAVPGVTMAIPIVEGQVLAQGFGDASTGALVRGIRADDLTKLKSVSEKIQAGDLV
GFASGSGVAIGSRMAEQLGIRVGGTITLTSPNGDVTPMGMNPRVKGYTVSAIFEMGMSEYDATIIFMPLEEAQLYFNAEG
LVQSIELFVEHPDAVDTLREPVEKAAGRQIFITDWRERNRTFFSALEVERNVMFMILTLIVLVAALNIISGLIMLVKDKG
SDIAILRTMGATSGSVMRIFFMTGAAIGVTGTIAGVVLGVVVCLNIESIRQFFSWVSGATLFDPELYFLSQLPADMNADE
TVTVVIMALALSFLATIFPAWRASRLDPVQALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=391, Percent_Identity=29.923273657289, Blast_Score=174, Evalue=9e-45,
Organism=Escherichia coli, GI1787360, Length=419, Percent_Identity=30.7875894988067, Blast_Score=161, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 47052; Mature: 46920

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAATDEQVQAAAPSSIPSGRPFSAFERMVAWRYLRSRRKEAFISVIAGFSFIGIMLGVG
CCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLIIVMAVMNGFRTELISRILGMNGHMIVQPLDGPLTNYADLATRFSAVPGVTMAIPIVE
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEC
GQVLAQGFGDASTGALVRGIRADDLTKLKSVSEKIQAGDLVGFASGSGVAIGSRMAEQLG
CHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHCC
IRVGGTITLTSPNGDVTPMGMNPRVKGYTVSAIFEMGMSEYDATIIFMPLEEAQLYFNAE
CEECCEEEEECCCCCEEECCCCCCCCCEEHHHHHHHCCHHCCCEEEEEECHHHHEEECHH
GLVQSIELFVEHPDAVDTLREPVEKAAGRQIFITDWRERNRTFFSALEVERNVMFMILTL
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECHHHCCHHHHHHHHHHHHHHHHHHHH
IVLVAALNIISGLIMLVKDKGSDIAILRTMGATSGSVMRIFFMTGAAIGVTGTIAGVVLG
HHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCEEEEEHHCCHHHHHHHHHHHHHH
VVVCLNIESIRQFFSWVSGATLFDPELYFLSQLPADMNADETVTVVIMALALSFLATIFP
HHHHHCHHHHHHHHHHHCCCEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AWRASRLDPVQALRYE
HHHCCCCCHHHHHCCC
>Mature Secondary Structure 
TAATDEQVQAAAPSSIPSGRPFSAFERMVAWRYLRSRRKEAFISVIAGFSFIGIMLGVG
CCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLIIVMAVMNGFRTELISRILGMNGHMIVQPLDGPLTNYADLATRFSAVPGVTMAIPIVE
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEC
GQVLAQGFGDASTGALVRGIRADDLTKLKSVSEKIQAGDLVGFASGSGVAIGSRMAEQLG
CHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHCC
IRVGGTITLTSPNGDVTPMGMNPRVKGYTVSAIFEMGMSEYDATIIFMPLEEAQLYFNAE
CEECCEEEEECCCCCEEECCCCCCCCCEEHHHHHHHCCHHCCCEEEEEECHHHHEEECHH
GLVQSIELFVEHPDAVDTLREPVEKAAGRQIFITDWRERNRTFFSALEVERNVMFMILTL
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECHHHCCHHHHHHHHHHHHHHHHHHHH
IVLVAALNIISGLIMLVKDKGSDIAILRTMGATSGSVMRIFFMTGAAIGVTGTIAGVVLG
HHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCEEEEEHHCCHHHHHHHHHHHHHH
VVVCLNIESIRQFFSWVSGATLFDPELYFLSQLPADMNADETVTVVIMALALSFLATIFP
HHHHHCHHHHHHHHHHHCCCEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AWRASRLDPVQALRYE
HHHCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]