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The map label for this gene is 150396128

Identifier: 150396128

GI number: 150396128

Start: 976968

End: 978635

Strand: Direct

Name: 150396128

Synonym: Smed_0905

Alternate gene names: NA

Gene position: 976968-978635 (Clockwise)

Preceding gene: 150396127

Following gene: 150396129

Centisome position: 25.83

GC content: 62.35

Gene sequence:

>1668_bases
ATGGCGCAGAATGAAGAATTGGTGTTCCTGCCGCTTGGCGGGGTGGGCGAAATAGGCATGAATCTTGGCCTCTACGGCTA
TGGACGGCCGGGCAGCCGCCAATGGATCATGGTCGATTGCGGAGTGACTTTCCCCGGCCCGGATCTGCCCGGGGTCGATC
TGGTCCTGCCTGACATCGCGTTTCTGGCCGAAGAACGCCGCAACCTCAAGGCGATCATTATCACGCATGCGCATGAGGAT
CATTACGGAGCCTTGAACGATCTGTGGCCCGGCTTGAACGTTCCCGTTTACGCCTCGCCGTTCACCGCGGGCATGCTGGA
GGCAAAGCGGGCATTCGAAAAGTCTCGCAGCGAAATCCCGATTACGATCTTCAAGCAGGGCGACCGCATAAATGTCGGAC
CCTTCAGCGTCGAAGCCGTTGGGGTCAATCATTCGATCCCTGAGCCGATGGCGCTCATCATCCGCACGCAGCTCGGTACC
GTTGTGCACACGGGCGACTGGAAGATCGACCTCGAGCCTTCGCTCGGCCCCTTGACCGACGAGAAGCGGCTTCGTCAGAT
CGGTGAGGAAGGCGTACTCGCGCTCATCTGCGATTCGACCAATGCCTTGCGCGAAGGCGTATCGCCCTCCGAACGGCAGG
TCTCCGAAAGCCTCTCCAAGATCATCGCCGACGCCGAGGGCCGGGTCGGGATCACCACCTTCTCCTCCAATGTCGGGCGC
ATCCGTTCGGTTGCCCAAGCGGCGGAGGCCGCGGGCCGGGAGGTGCTCCTGCTCGGCAGCTCGATGAAGCGCGTCGTCGA
CGTTGCCCGGGACGTCGGGCTGATGGAAGGGCTGAGACCATTTCTGGCCGAAGACGAGTTCGGCTACATCCCGCGCGACA
AGGTCGTGGTCATCCTGACGGGCAGCCAGGGAGAGCCGCGCGCGGCGCTTGCCAAGATCGCCCGTGACGAGATGCGCAAC
GTGGCCTTCTCGGCCGGCGACACGATCGTCTTTTCCTCGCGCACGATCCCGGGCAATGAAAAGGCGATCAACGATATCAA
GAACGGGCTGATCGAGCAGGGCATTCACATCATCACGGATAGTGAGGCGCTCGTGCATGTGTCCGGTCACCCGCGGCGCA
ACGAGCTCCAGCAGATGTACCAATGGGTCAAGCCGCAAATCGTCGTGCCGGTGCATGGCGAGGCCGCGCATCTGACGGCG
CATGCGGAGCTTGCACTGCAATCGGGCATCCCGAGCGTCCCGAGACTGCGCAATGGCGAAATGCTACGGCTCGCGCCGGG
ACCGGCGGAAGTCGTCGACCAAGCACCTCACGGGCGCATCTACAAGGACGGCACCCTCATCGGTGACTTCGAAGAGATGG
GCATCGGCGAGCGCCGCAAGCTCTCTTTTGCCGGTCACGTCTCCGTCAGTGTCGTGCTCGACAACCGCTACGACTTCCTG
GGCGATCCGGATGTCGTCCCGATCGGGCTCCCCGAATATGATGACGAGGGAGAGTCGATGGAGGATACGCTCTATGATGC
GGTTCTCGGAGCGGTGGAAAGCATTCCCCGGGCAAAGCGGAAGGACCTCGCCATGCTGCAGGAAGCCGTTCGCCGCGCCG
TACGCAGCACCGCCAATCAGGTCTGGGGCAAGAAGCCGGTCGTCACCGTGTTTGTCACGAAGGTCTGA

Upstream 100 bases:

>100_bases
GACGGCCGGCTTATACTCGACACTGGTTCCGGACCGCCGCAAACCATTGCGGCCGGCGACGTATTTTTTGGATGATTAAA
AAGTAAAGGCGCATCACGAC

Downstream 100 bases:

>100_bases
TCTGGGGCTTGGGTCCGTCCGGGCCGTGCGTCCTGACGCAGGAAGTGGAGCGTGCGATGTTGGGAAAAGTGAACCACGTG
GCAATCGCGGTGCCGGATCT

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MAQNEELVFLPLGGVGEIGMNLGLYGYGRPGSRQWIMVDCGVTFPGPDLPGVDLVLPDIAFLAEERRNLKAIIITHAHED
HYGALNDLWPGLNVPVYASPFTAGMLEAKRAFEKSRSEIPITIFKQGDRINVGPFSVEAVGVNHSIPEPMALIIRTQLGT
VVHTGDWKIDLEPSLGPLTDEKRLRQIGEEGVLALICDSTNALREGVSPSERQVSESLSKIIADAEGRVGITTFSSNVGR
IRSVAQAAEAAGREVLLLGSSMKRVVDVARDVGLMEGLRPFLAEDEFGYIPRDKVVVILTGSQGEPRAALAKIARDEMRN
VAFSAGDTIVFSSRTIPGNEKAINDIKNGLIEQGIHIITDSEALVHVSGHPRRNELQQMYQWVKPQIVVPVHGEAAHLTA
HAELALQSGIPSVPRLRNGEMLRLAPGPAEVVDQAPHGRIYKDGTLIGDFEEMGIGERRKLSFAGHVSVSVVLDNRYDFL
GDPDVVPIGLPEYDDEGESMEDTLYDAVLGAVESIPRAKRKDLAMLQEAVRRAVRSTANQVWGKKPVVTVFVTKV

Sequences:

>Translated_555_residues
MAQNEELVFLPLGGVGEIGMNLGLYGYGRPGSRQWIMVDCGVTFPGPDLPGVDLVLPDIAFLAEERRNLKAIIITHAHED
HYGALNDLWPGLNVPVYASPFTAGMLEAKRAFEKSRSEIPITIFKQGDRINVGPFSVEAVGVNHSIPEPMALIIRTQLGT
VVHTGDWKIDLEPSLGPLTDEKRLRQIGEEGVLALICDSTNALREGVSPSERQVSESLSKIIADAEGRVGITTFSSNVGR
IRSVAQAAEAAGREVLLLGSSMKRVVDVARDVGLMEGLRPFLAEDEFGYIPRDKVVVILTGSQGEPRAALAKIARDEMRN
VAFSAGDTIVFSSRTIPGNEKAINDIKNGLIEQGIHIITDSEALVHVSGHPRRNELQQMYQWVKPQIVVPVHGEAAHLTA
HAELALQSGIPSVPRLRNGEMLRLAPGPAEVVDQAPHGRIYKDGTLIGDFEEMGIGERRKLSFAGHVSVSVVLDNRYDFL
GDPDVVPIGLPEYDDEGESMEDTLYDAVLGAVESIPRAKRKDLAMLQEAVRRAVRSTANQVWGKKPVVTVFVTKV
>Mature_554_residues
AQNEELVFLPLGGVGEIGMNLGLYGYGRPGSRQWIMVDCGVTFPGPDLPGVDLVLPDIAFLAEERRNLKAIIITHAHEDH
YGALNDLWPGLNVPVYASPFTAGMLEAKRAFEKSRSEIPITIFKQGDRINVGPFSVEAVGVNHSIPEPMALIIRTQLGTV
VHTGDWKIDLEPSLGPLTDEKRLRQIGEEGVLALICDSTNALREGVSPSERQVSESLSKIIADAEGRVGITTFSSNVGRI
RSVAQAAEAAGREVLLLGSSMKRVVDVARDVGLMEGLRPFLAEDEFGYIPRDKVVVILTGSQGEPRAALAKIARDEMRNV
AFSAGDTIVFSSRTIPGNEKAINDIKNGLIEQGIHIITDSEALVHVSGHPRRNELQQMYQWVKPQIVVPVHGEAAHLTAH
AELALQSGIPSVPRLRNGEMLRLAPGPAEVVDQAPHGRIYKDGTLIGDFEEMGIGERRKLSFAGHVSVSVVLDNRYDFLG
DPDVVPIGLPEYDDEGESMEDTLYDAVLGAVESIPRAKRKDLAMLQEAVRRAVRSTANQVWGKKPVVTVFVTKV

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 60372; Mature: 60241

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQNEELVFLPLGGVGEIGMNLGLYGYGRPGSRQWIMVDCGVTFPGPDLPGVDLVLPDIA
CCCCCCEEEEECCCCCHHCCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHH
FLAEERRNLKAIIITHAHEDHYGALNDLWPGLNVPVYASPFTAGMLEAKRAFEKSRSEIP
HHHHHCCCCEEEEEEECCCCCCCCHHHCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCC
ITIFKQGDRINVGPFSVEAVGVNHSIPEPMALIIRTQLGTVVHTGDWKIDLEPSLGPLTD
EEEEECCCEEECCCEEEEEEECCCCCCCCHHHHEEHHCCCEEECCCEEEEECCCCCCCCC
EKRLRQIGEEGVLALICDSTNALREGVSPSERQVSESLSKIIADAEGRVGITTFSSNVGR
HHHHHHCCCCCEEEEEECCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHH
IRSVAQAAEAAGREVLLLGSSMKRVVDVARDVGLMEGLRPFLAEDEFGYIPRDKVVVILT
HHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
GSQGEPRAALAKIARDEMRNVAFSAGDTIVFSSRTIPGNEKAINDIKNGLIEQGIHIITD
CCCCCCHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEC
SEALVHVSGHPRRNELQQMYQWVKPQIVVPVHGEAAHLTAHAELALQSGIPSVPRLRNGE
CCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCEEEEHHHHHHHHCCCCCCCCCCCCC
MLRLAPGPAEVVDQAPHGRIYKDGTLIGDFEEMGIGERRKLSFAGHVSVSVVLDNRYDFL
EEEECCCCHHHHCCCCCCCEEECCCEEECHHHCCCCCCEEEEEECCEEEEEEEECCCCCC
GDPDVVPIGLPEYDDEGESMEDTLYDAVLGAVESIPRAKRKDLAMLQEAVRRAVRSTANQ
CCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VWGKKPVVTVFVTKV
HCCCCCEEEEEEEEC
>Mature Secondary Structure 
AQNEELVFLPLGGVGEIGMNLGLYGYGRPGSRQWIMVDCGVTFPGPDLPGVDLVLPDIA
CCCCCEEEEECCCCCHHCCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHH
FLAEERRNLKAIIITHAHEDHYGALNDLWPGLNVPVYASPFTAGMLEAKRAFEKSRSEIP
HHHHHCCCCEEEEEEECCCCCCCCHHHCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCC
ITIFKQGDRINVGPFSVEAVGVNHSIPEPMALIIRTQLGTVVHTGDWKIDLEPSLGPLTD
EEEEECCCEEECCCEEEEEEECCCCCCCCHHHHEEHHCCCEEECCCEEEEECCCCCCCCC
EKRLRQIGEEGVLALICDSTNALREGVSPSERQVSESLSKIIADAEGRVGITTFSSNVGR
HHHHHHCCCCCEEEEEECCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHH
IRSVAQAAEAAGREVLLLGSSMKRVVDVARDVGLMEGLRPFLAEDEFGYIPRDKVVVILT
HHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
GSQGEPRAALAKIARDEMRNVAFSAGDTIVFSSRTIPGNEKAINDIKNGLIEQGIHIITD
CCCCCCHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEC
SEALVHVSGHPRRNELQQMYQWVKPQIVVPVHGEAAHLTAHAELALQSGIPSVPRLRNGE
CCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCEEEEHHHHHHHHCCCCCCCCCCCCC
MLRLAPGPAEVVDQAPHGRIYKDGTLIGDFEEMGIGERRKLSFAGHVSVSVVLDNRYDFL
EEEECCCCHHHHCCCCCCCEEECCCEEECHHHCCCCCCEEEEEECCEEEEEEEECCCCCC
GDPDVVPIGLPEYDDEGESMEDTLYDAVLGAVESIPRAKRKDLAMLQEAVRRAVRSTANQ
CCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VWGKKPVVTVFVTKV
HCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]