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The map label for this gene is mrpE [H]

Identifier: 150395835

GI number: 150395835

Start: 660550

End: 661026

Strand: Direct

Name: mrpE [H]

Synonym: Smed_0611

Alternate gene names: 150395835

Gene position: 660550-661026 (Clockwise)

Preceding gene: 150395834

Following gene: 150395836

Centisome position: 17.47

GC content: 59.33

Gene sequence:

>477_bases
ATGAAGTTCCTGCTGACCAACGTAATTTTCACGCTGATCTGGGGAGCAATCAGCGCCAGCTTCACGCCCGCGAACCTATT
GCTGGGCTTCGCAGCCGGCGCCCTGTCGCTCTGGCTGATCCGACGGGAGCTGCGCCCGGTGACTTATCCGTTGAGGCCCT
TGCGGCTTCTGCTGCTCGCATTGCTGTTTTTCAGGGAGTTGGCGATCTCCGCAACCAAGGTCGCGATCCGGGTTCTGCGT
CCGAATATGGAACTGAAGCCCGGGATTTTTGCCTATCCGCTCGCGGTTAACAGTGATTTCGAGATAACGCTGCTCGCCAA
CCTGATCACACTGACGCCGGGAACTCTGTCGGTGGATGTCTCCGAAGATCGCAAGACCCTCTATGTACATGCGCTCGATT
GCGCCGATCCGGCAGCCTTGCGGCGAGACATTGCCGGCGGCTTCGAGCGCCGAATCCGGGAGGCCTTCGAACGATGA

Upstream 100 bases:

>100_bases
TCTACCCCGAGCCGCTGCTTGCGATGATCCAGAACGCGGCGGCTGGTCTGGCCGAGCCCTCCGCTTACCTGAATTCAGTC
TTTCCCGCCGGAGGTCCGCA

Downstream 100 bases:

>100_bases
CGCCCGCTGCAGTTCTGAGCACGGCTTCGGGCCTGGCGCTCGTGCTCCTCTCTCTGGCGCTGCTGATGACGGTGCTGCGC
ATTGTTCGCGGGCCAACACT

Product: putative monovalent cation/H+ antiporter subunit E

Products: NA

Alternate protein names: Mrp complex subunit E; Multiple resistance and pH homeostasis protein E [H]

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MKFLLTNVIFTLIWGAISASFTPANLLLGFAAGALSLWLIRRELRPVTYPLRPLRLLLLALLFFRELAISATKVAIRVLR
PNMELKPGIFAYPLAVNSDFEITLLANLITLTPGTLSVDVSEDRKTLYVHALDCADPAALRRDIAGGFERRIREAFER

Sequences:

>Translated_158_residues
MKFLLTNVIFTLIWGAISASFTPANLLLGFAAGALSLWLIRRELRPVTYPLRPLRLLLLALLFFRELAISATKVAIRVLR
PNMELKPGIFAYPLAVNSDFEITLLANLITLTPGTLSVDVSEDRKTLYVHALDCADPAALRRDIAGGFERRIREAFER
>Mature_158_residues
MKFLLTNVIFTLIWGAISASFTPANLLLGFAAGALSLWLIRRELRPVTYPLRPLRLLLLALLFFRELAISATKVAIRVLR
PNMELKPGIFAYPLAVNSDFEITLLANLITLTPGTLSVDVSEDRKTLYVHALDCADPAALRRDIAGGFERRIREAFER

Specific function: Mrp complex is a Na(+)/H(+) antiporter involved in Na(+) excretion and Na(+) resistance [H]

COG id: COG1863

COG function: function code P; Multisubunit Na+/H+ antiporter, MnhE subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002758 [H]

Pfam domain/function: PF01899 MNHE [H]

EC number: NA

Molecular weight: Translated: 17681; Mature: 17681

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLLTNVIFTLIWGAISASFTPANLLLGFAAGALSLWLIRRELRPVTYPLRPLRLLLLA
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LLFFRELAISATKVAIRVLRPNMELKPGIFAYPLAVNSDFEITLLANLITLTPGTLSVDV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEHHHHHHHHCCCCEEEEEE
SEDRKTLYVHALDCADPAALRRDIAGGFERRIREAFER
CCCCEEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MKFLLTNVIFTLIWGAISASFTPANLLLGFAAGALSLWLIRRELRPVTYPLRPLRLLLLA
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LLFFRELAISATKVAIRVLRPNMELKPGIFAYPLAVNSDFEITLLANLITLTPGTLSVDV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEHHHHHHHHCCCCEEEEEE
SEDRKTLYVHALDCADPAALRRDIAGGFERRIREAFER
CCCCEEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11356194 [H]