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The map label for this gene is ilvE [H]

Identifier: 150395809

GI number: 150395809

Start: 634388

End: 635269

Strand: Direct

Name: ilvE [H]

Synonym: Smed_0585

Alternate gene names: 150395809

Gene position: 634388-635269 (Clockwise)

Preceding gene: 150395803

Following gene: 150395811

Centisome position: 16.77

GC content: 63.27

Gene sequence:

>882_bases
ATGGCCGTCGATACATCCCCCCGATCCACCACCTGGACCTATGTCGACGGCGAATGGCTTGCCGGCAACCCGCCGCTGAT
CGGCCCGACATCCCATGCGATGTGGCTCGGTTCGACGGTATTCGATGGCGCGCGCTGGTTCGATGGCATCGCGCCGGATC
TGGATCTCCATTGCCGGCGCGTCAACCGATCCGCCGAAGCCTTGGGTCTAAGGCCGACGATGACCGCCCAGGCGATCGAG
GCACTCGCCTGGGAAGGCGTGAAGAAGTTCGACGGGCAGACGGCCATCTACGTGAAGCCGATGTATTGGGGCGAGCACGG
CTCCTGGAGCGTCGTTGCGGTGGACCCTGAATCCACACGCTTCGCGCTTTGCCTGTTCGAGGCGCCAATGGGCAACGGCC
ATGCCGGCTCGTCACTGACGCTGTCGCCTTTCCGGCGACCAACGGTCGAATGCATGCCGACGGACGCCAAGGCCGGCTGC
CTTTATCCGAACAATGCCCGTATCCTCAATGAGGCTCGCTCGCGCGGTTTCGACAATGCTCTGGTGCGCGATATGCTCGG
CAACATCGCCGAGACCGGCTCCTCCAATATCTTCATGGTGAGGGACGGCGTCGTCTTCACGCCGGCCGCCAACAAGACCT
TTCTCGCCGGTATCACCCGCTCGCGCGTGATGGACCTTCTGCGCGAGGCAGGTCTCCAAGTGATCGAGACCGACTTGACC
ATGGCCGATTTCGAGGCGGCCGACGAGATCTTCACCTCGGGCAACTATTCCAAAGTGCTGCCCGTCACCCGTATCGAGCA
GCGCGAGCTGCAGGCCGGCCCGGTGACGGGCAAGGCGCGAGATCTTTATATGGACTGGGCGCACACAACCGGACGCCGAT
AG

Upstream 100 bases:

>100_bases
GGCTCCAGATTGGACGCCATGACATTTTTTGATGTACGCATTCACCCTCATGCTGTTCTTTCCGGCTAGAGCGGAAGTGT
TCAATGAGAAGGAGACGCCG

Downstream 100 bases:

>100_bases
TCTCGCTTGTTCTCTATCGTTACGGCTCGAAGGGACGCACGACGACGTCGGGCGACGAGCGCGTGTTCGGACCATGATAG
ACCGCTTCGACATTGTTCCC

Product: aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MAVDTSPRSTTWTYVDGEWLAGNPPLIGPTSHAMWLGSTVFDGARWFDGIAPDLDLHCRRVNRSAEALGLRPTMTAQAIE
ALAWEGVKKFDGQTAIYVKPMYWGEHGSWSVVAVDPESTRFALCLFEAPMGNGHAGSSLTLSPFRRPTVECMPTDAKAGC
LYPNNARILNEARSRGFDNALVRDMLGNIAETGSSNIFMVRDGVVFTPAANKTFLAGITRSRVMDLLREAGLQVIETDLT
MADFEAADEIFTSGNYSKVLPVTRIEQRELQAGPVTGKARDLYMDWAHTTGRR

Sequences:

>Translated_293_residues
MAVDTSPRSTTWTYVDGEWLAGNPPLIGPTSHAMWLGSTVFDGARWFDGIAPDLDLHCRRVNRSAEALGLRPTMTAQAIE
ALAWEGVKKFDGQTAIYVKPMYWGEHGSWSVVAVDPESTRFALCLFEAPMGNGHAGSSLTLSPFRRPTVECMPTDAKAGC
LYPNNARILNEARSRGFDNALVRDMLGNIAETGSSNIFMVRDGVVFTPAANKTFLAGITRSRVMDLLREAGLQVIETDLT
MADFEAADEIFTSGNYSKVLPVTRIEQRELQAGPVTGKARDLYMDWAHTTGRR
>Mature_292_residues
AVDTSPRSTTWTYVDGEWLAGNPPLIGPTSHAMWLGSTVFDGARWFDGIAPDLDLHCRRVNRSAEALGLRPTMTAQAIEA
LAWEGVKKFDGQTAIYVKPMYWGEHGSWSVVAVDPESTRFALCLFEAPMGNGHAGSSLTLSPFRRPTVECMPTDAKAGCL
YPNNARILNEARSRGFDNALVRDMLGNIAETGSSNIFMVRDGVVFTPAANKTFLAGITRSRVMDLLREAGLQVIETDLTM
ADFEAADEIFTSGNYSKVLPVTRIEQRELQAGPVTGKARDLYMDWAHTTGRR

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=291, Percent_Identity=28.5223367697594, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 32167; Mature: 32036

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVDTSPRSTTWTYVDGEWLAGNPPLIGPTSHAMWLGSTVFDGARWFDGIAPDLDLHCRR
CCCCCCCCCCEEEEECCEEECCCCCCCCCCCCCEEECCHHHCCHHHHCCCCCCHHHHHHH
VNRSAEALGLRPTMTAQAIEALAWEGVKKFDGQTAIYVKPMYWGEHGSWSVVAVDPESTR
HCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCEEEEEECCCCCE
FALCLFEAPMGNGHAGSSLTLSPFRRPTVECMPTDAKAGCLYPNNARILNEARSRGFDNA
EEEEEEECCCCCCCCCCCEEECCCCCCCEEEECCCCCCCEECCCCHHHHHHHHHCCCCHH
LVRDMLGNIAETGSSNIFMVRDGVVFTPAANKTFLAGITRSRVMDLLREAGLQVIETDLT
HHHHHHHHHHHCCCCCEEEEECCEEECCCCCCEEEEHHHHHHHHHHHHHCCCEEEECCCC
MADFEAADEIFTSGNYSKVLPVTRIEQRELQAGPVTGKARDLYMDWAHTTGRR
HHHHHHHHHHHCCCCCEEECCCCHHHHHHHCCCCCCCCCCEEEEEHHHCCCCC
>Mature Secondary Structure 
AVDTSPRSTTWTYVDGEWLAGNPPLIGPTSHAMWLGSTVFDGARWFDGIAPDLDLHCRR
CCCCCCCCCEEEEECCEEECCCCCCCCCCCCCEEECCHHHCCHHHHCCCCCCHHHHHHH
VNRSAEALGLRPTMTAQAIEALAWEGVKKFDGQTAIYVKPMYWGEHGSWSVVAVDPESTR
HCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCEEEEEECCCCCE
FALCLFEAPMGNGHAGSSLTLSPFRRPTVECMPTDAKAGCLYPNNARILNEARSRGFDNA
EEEEEEECCCCCCCCCCCEEECCCCCCCEEEECCCCCCCEECCCCHHHHHHHHHCCCCHH
LVRDMLGNIAETGSSNIFMVRDGVVFTPAANKTFLAGITRSRVMDLLREAGLQVIETDLT
HHHHHHHHHHHCCCCCEEEEECCEEECCCCCCEEEEHHHHHHHHHHHHHCCCEEEECCCC
MADFEAADEIFTSGNYSKVLPVTRIEQRELQAGPVTGKARDLYMDWAHTTGRR
HHHHHHHHHHHCCCCCEEECCCCHHHHHHHCCCCCCCCCCEEEEEHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA