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The map label for this gene is yciR [C]

Identifier: 150395798

GI number: 150395798

Start: 622989

End: 625307

Strand: Direct

Name: yciR [C]

Synonym: Smed_0574

Alternate gene names: 150395798

Gene position: 622989-625307 (Clockwise)

Preceding gene: 150395796

Following gene: 150395799

Centisome position: 16.47

GC content: 61.92

Gene sequence:

>2319_bases
TTGGCAGACAAGACGTCCCGCAGCATCCGTTATGCCGACCTGAACGCGGGCGACAATGCGGAAACGCGCCGGCTGATCGA
TGCCGGCAATCGCCTCGCCGACGAAGTCGCACGCCTGTTTCCGTCTCAGCCGGATATTGCCGACCGCCACTATTGGCTCG
AGGCGATGATCAACCACGTCCCGGACTACATCTATGCCAAGGACACGGAGGGCCGTTTCCTGATCGCCAATGAGGTGACG
GTCGCCGACAATGGCCTCGAAAGCCTGCAGGATCTCGTCGGCAAGACCGATTTCGATCTGCATCCGCATGAATTTGCCCA
GGCGGTCGCTGGTACGGAGCGGCGTGTGCTGGAGACCGGCGAACCGATTTTTGGTATCGAGGAACGTGCGATCGTCACGA
AGGGCCGCGACCGTTGGCTCATGACCTCGAAAGTGCCCTTGCGGAGCAAGAGCGGAAAGATCATCGGCATCGTCGGCATC
TCGCGTGACATCACCGATCGGAAGTCGGCGGAGCGCCTGCTCGAAGGGCAGGCCCGGTTATTGGAAATGATAGCCAAGGG
CAAGCCGCTGACCGAATTCTTCAACGAGCTGGTGCTGCTGATCGAGGCACTTCTTCCCGGTATCAAAGGCTCTATCCTGC
TTTTGTCCGAAGACGGCCGGCATCTCCTGCACGGCGCTGCTCCCAGCCTCGACCGGGCGTATAGCGCTGCTGTTCATGCG
TTGGAAATAGGCCCGAATGCGGGCTCTTGCGGAACGGCCGCCTGGCGCGGCGAACAGGTCATCGTCTCCGATGTCTACGC
CGACCCGCTCTGGGCGGACTACGCTCTTCTCCTGAAATCTTCCGGTCTCCGTTCCTGCTGGTCCACGCCCATCCTGTCGC
GCGAGCGCAAGGTGCTCGGCACATTCGCGCTCTACGCACATGAGGTCGCAACCCCTTGCGAGCAGGAGCAGGAACTGATT
GCCATGGCCGCTCACCTCGCCGGAATCGCCATCGAGCGCAAGCGGGCGGAGGACCGTATCAGTTTCTTGGCCCACCATGA
CGCCTTGACGGGCCTGCCGAACCGCGTCCTTTTTGAAGAGCAGGTCGACGGCATGCTCGAGGAGATCCGCGAGCGGGACC
AATGCGCCGTGCTCGCCTTTCTCGACCTCGACAATTTCAAACTGATCAACGACAGCCTTGGCCACGCGGCAGGTGATGAG
CTCCTGAAAGCCGTCGCAGGGCGCATGCGGGCCTCCGTGCGGAAAGCCGATTTTGTCGTGCGCGTCGGCGGCGACGAGTT
CATCATTCTCCTGAACGGGTTGCCGAAGGAGCGGGATATCGTGCTGTCGCGGCTTGAGGACATCCGCTCTGCAATCGCCA
TGCCGCTGCAGTTGCAGGGCCGCTCCCTGCAGGTCAGCTGCAGCATGGGAGTGGCTTGCTTCCCCAACCAGGGAAGAACG
GCGGGTGAACTGCTCGCCAACGCCGACATGGCCATGTACCGCGCCAAGGAACTCGGCCGCGACAACATACAGGTCTTTAC
CGAGGAGATGGCGGCAAGAGCTCATGAAAGACTCCAATGGCAGGAGGAGCTTCGTGAGGCACTTGCGGGGGAGGAGTTCC
TGCTGCATTTCCAGCCGCAGATGAATCTCGGCACCGGGCGCATCTTCGCGGCGGAGGCACTGTTGCGTTGGAACCACCCG
GTGCGCGGCATCATCTCGCCTTCGGTGTTCATCCCGCTCGCCGAGGAGACCGGGCTTATCGTGCCGATCGGAGACTGGGC
GCTGCGTGCCGCCTGTCGCCAGCTGAAGGCCTGGCAGGATGCCGGCCTGCCACCGCTGATCATCAGCGTCAATGTTTCCG
CTCGGCAGTTCCGCGAACGCAACTGGGCATCGCGGGTGGCGGAAATTCTGAAGGAGACCGGGCTCGAGGCCCGTTACCTC
GAGCTCGAGCTCACCGAGAGTCTCATCATGCAGGACGTGCCGGGGGCAATCGCCACAATGCACGCGCTGGAAGCGATCGG
CGTTCACCTTGCGATCGATGATTTCGGGACGGGCTATTCCAGCCTCAGTGCGCTTAAGCGCTTTCCGGTACGCCGTCTGA
AAATCGACCGGTCCTTCGTTACGGACATTCCGCTCGATGCCGACGACATGGCGATCACGTCCGCCATTATCTCGCTTGCA
CAGAAGCTCGGCCTGCGTGTGATCGCCGAGGGTGTCGAGAGCGAGGCGCAGGTCGAGTTTCTCCAGAAGGCCGGCTGCGA
CGAAATCCAAGGCTATTTCTTCAGCCGTCCTTTGTCGGCCGAGGCTTTCGAAAGCCTGCTTTCCTCCGCGCGGCCGTAA

Upstream 100 bases:

>100_bases
GTTCTTCCGCAACCTTCAGACGATTTTTCGCAGTCGAGTTTAGGGAAGCATAACCTCTTTCCGCTAAACCTGCGCGAGCG
CCGCTCCTCGGAGGTTTAGC

Downstream 100 bases:

>100_bases
TCCGGTCGCCGGCTGAAACCGGCAGTTGCGGAATGTGGTGTCAGTATTGTGATCTGAAGTTTGCTGACACAGGTGCCGCT
CCGGCCGTAAATGCAAACTG

Product: PAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 772; Mature: 771

Protein sequence:

>772_residues
MADKTSRSIRYADLNAGDNAETRRLIDAGNRLADEVARLFPSQPDIADRHYWLEAMINHVPDYIYAKDTEGRFLIANEVT
VADNGLESLQDLVGKTDFDLHPHEFAQAVAGTERRVLETGEPIFGIEERAIVTKGRDRWLMTSKVPLRSKSGKIIGIVGI
SRDITDRKSAERLLEGQARLLEMIAKGKPLTEFFNELVLLIEALLPGIKGSILLLSEDGRHLLHGAAPSLDRAYSAAVHA
LEIGPNAGSCGTAAWRGEQVIVSDVYADPLWADYALLLKSSGLRSCWSTPILSRERKVLGTFALYAHEVATPCEQEQELI
AMAAHLAGIAIERKRAEDRISFLAHHDALTGLPNRVLFEEQVDGMLEEIRERDQCAVLAFLDLDNFKLINDSLGHAAGDE
LLKAVAGRMRASVRKADFVVRVGGDEFIILLNGLPKERDIVLSRLEDIRSAIAMPLQLQGRSLQVSCSMGVACFPNQGRT
AGELLANADMAMYRAKELGRDNIQVFTEEMAARAHERLQWQEELREALAGEEFLLHFQPQMNLGTGRIFAAEALLRWNHP
VRGIISPSVFIPLAEETGLIVPIGDWALRAACRQLKAWQDAGLPPLIISVNVSARQFRERNWASRVAEILKETGLEARYL
ELELTESLIMQDVPGAIATMHALEAIGVHLAIDDFGTGYSSLSALKRFPVRRLKIDRSFVTDIPLDADDMAITSAIISLA
QKLGLRVIAEGVESEAQVEFLQKAGCDEIQGYFFSRPLSAEAFESLLSSARP

Sequences:

>Translated_772_residues
MADKTSRSIRYADLNAGDNAETRRLIDAGNRLADEVARLFPSQPDIADRHYWLEAMINHVPDYIYAKDTEGRFLIANEVT
VADNGLESLQDLVGKTDFDLHPHEFAQAVAGTERRVLETGEPIFGIEERAIVTKGRDRWLMTSKVPLRSKSGKIIGIVGI
SRDITDRKSAERLLEGQARLLEMIAKGKPLTEFFNELVLLIEALLPGIKGSILLLSEDGRHLLHGAAPSLDRAYSAAVHA
LEIGPNAGSCGTAAWRGEQVIVSDVYADPLWADYALLLKSSGLRSCWSTPILSRERKVLGTFALYAHEVATPCEQEQELI
AMAAHLAGIAIERKRAEDRISFLAHHDALTGLPNRVLFEEQVDGMLEEIRERDQCAVLAFLDLDNFKLINDSLGHAAGDE
LLKAVAGRMRASVRKADFVVRVGGDEFIILLNGLPKERDIVLSRLEDIRSAIAMPLQLQGRSLQVSCSMGVACFPNQGRT
AGELLANADMAMYRAKELGRDNIQVFTEEMAARAHERLQWQEELREALAGEEFLLHFQPQMNLGTGRIFAAEALLRWNHP
VRGIISPSVFIPLAEETGLIVPIGDWALRAACRQLKAWQDAGLPPLIISVNVSARQFRERNWASRVAEILKETGLEARYL
ELELTESLIMQDVPGAIATMHALEAIGVHLAIDDFGTGYSSLSALKRFPVRRLKIDRSFVTDIPLDADDMAITSAIISLA
QKLGLRVIAEGVESEAQVEFLQKAGCDEIQGYFFSRPLSAEAFESLLSSARP
>Mature_771_residues
ADKTSRSIRYADLNAGDNAETRRLIDAGNRLADEVARLFPSQPDIADRHYWLEAMINHVPDYIYAKDTEGRFLIANEVTV
ADNGLESLQDLVGKTDFDLHPHEFAQAVAGTERRVLETGEPIFGIEERAIVTKGRDRWLMTSKVPLRSKSGKIIGIVGIS
RDITDRKSAERLLEGQARLLEMIAKGKPLTEFFNELVLLIEALLPGIKGSILLLSEDGRHLLHGAAPSLDRAYSAAVHAL
EIGPNAGSCGTAAWRGEQVIVSDVYADPLWADYALLLKSSGLRSCWSTPILSRERKVLGTFALYAHEVATPCEQEQELIA
MAAHLAGIAIERKRAEDRISFLAHHDALTGLPNRVLFEEQVDGMLEEIRERDQCAVLAFLDLDNFKLINDSLGHAAGDEL
LKAVAGRMRASVRKADFVVRVGGDEFIILLNGLPKERDIVLSRLEDIRSAIAMPLQLQGRSLQVSCSMGVACFPNQGRTA
GELLANADMAMYRAKELGRDNIQVFTEEMAARAHERLQWQEELREALAGEEFLLHFQPQMNLGTGRIFAAEALLRWNHPV
RGIISPSVFIPLAEETGLIVPIGDWALRAACRQLKAWQDAGLPPLIISVNVSARQFRERNWASRVAEILKETGLEARYLE
LELTESLIMQDVPGAIATMHALEAIGVHLAIDDFGTGYSSLSALKRFPVRRLKIDRSFVTDIPLDADDMAITSAIISLAQ
KLGLRVIAEGVESEAQVEFLQKAGCDEIQGYFFSRPLSAEAFESLLSSARP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=438, Percent_Identity=39.4977168949772, Blast_Score=311, Evalue=1e-85,
Organism=Escherichia coli, GI87081921, Length=486, Percent_Identity=32.7160493827161, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI226510982, Length=479, Percent_Identity=31.9415448851775, Blast_Score=215, Evalue=8e-57,
Organism=Escherichia coli, GI1790496, Length=243, Percent_Identity=35.8024691358025, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI87081980, Length=259, Percent_Identity=35.9073359073359, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1786507, Length=244, Percent_Identity=35.655737704918, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI1787055, Length=295, Percent_Identity=32.8813559322034, Blast_Score=136, Evalue=7e-33,
Organism=Escherichia coli, GI1788502, Length=249, Percent_Identity=32.1285140562249, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87081845, Length=239, Percent_Identity=33.0543933054393, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87081743, Length=249, Percent_Identity=33.7349397590361, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788849, Length=438, Percent_Identity=26.4840182648402, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788381, Length=187, Percent_Identity=36.3636363636364, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI87082096, Length=419, Percent_Identity=26.2529832935561, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1786584, Length=175, Percent_Identity=32.5714285714286, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI87081881, Length=173, Percent_Identity=38.150289017341, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI87081977, Length=248, Percent_Identity=29.0322580645161, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1787262, Length=169, Percent_Identity=31.9526627218935, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1788956, Length=155, Percent_Identity=35.4838709677419, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI145693134, Length=134, Percent_Identity=36.5671641791045, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87082007, Length=172, Percent_Identity=32.5581395348837, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI87081974, Length=91, Percent_Identity=37.3626373626374, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1787816, Length=171, Percent_Identity=29.2397660818713, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1787802, Length=172, Percent_Identity=27.3255813953488, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1787410, Length=221, Percent_Identity=26.6968325791855, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787056, Length=163, Percent_Identity=32.5153374233129, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789650, Length=488, Percent_Identity=20.6967213114754, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788085, Length=166, Percent_Identity=27.1084337349398, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 85300; Mature: 85169

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50113 PAC ; PS00639 THIOL_PROTEASE_HIS ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKTSRSIRYADLNAGDNAETRRLIDAGNRLADEVARLFPSQPDIADRHYWLEAMINHV
CCCCCCCCEEEEECCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
PDYIYAKDTEGRFLIANEVTVADNGLESLQDLVGKTDFDLHPHEFAQAVAGTERRVLETG
CCCEEEECCCCCEEEEECEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHCC
EPIFGIEERAIVTKGRDRWLMTSKVPLRSKSGKIIGIVGISRDITDRKSAERLLEGQARL
CCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
LEMIAKGKPLTEFFNELVLLIEALLPGIKGSILLLSEDGRHLLHGAAPSLDRAYSAAVHA
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHCCCCCHHHHHHHHHHE
LEIGPNAGSCGTAAWRGEQVIVSDVYADPLWADYALLLKSSGLRSCWSTPILSRERKVLG
EEECCCCCCCCCCCCCCCEEEEEHHHCCCHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHH
TFALYAHEVATPCEQEQELIAMAAHLAGIAIERKRAEDRISFLAHHDALTGLPNRVLFEE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
QVDGMLEEIRERDQCAVLAFLDLDNFKLINDSLGHAAGDELLKAVAGRMRASVRKADFVV
HHHHHHHHHHCCCCEEEEEEEECCCCEEECHHCCCCHHHHHHHHHHHHHHHHHHHCCEEE
RVGGDEFIILLNGLPKERDIVLSRLEDIRSAIAMPLQLQGRSLQVSCSMGVACFPNQGRT
EECCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCEEECCCCCCH
AGELLANADMAMYRAKELGRDNIQVFTEEMAARAHERLQWQEELREALAGEEFLLHFQPQ
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
MNLGTGRIFAAEALLRWNHPVRGIISPSVFIPLAEETGLIVPIGDWALRAACRQLKAWQD
CCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHHH
AGLPPLIISVNVSARQFRERNWASRVAEILKETGLEARYLELELTESLIMQDVPGAIATM
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCHHHHHH
HALEAIGVHLAIDDFGTGYSSLSALKRFPVRRLKIDRSFVTDIPLDADDMAITSAIISLA
HHHHHHCEEEEEECCCCCHHHHHHHHHCCHHHEEECHHHHCCCCCCCHHHHHHHHHHHHH
QKLGLRVIAEGVESEAQVEFLQKAGCDEIQGYFFSRPLSAEAFESLLSSARP
HHHHHHHHHHHCCHHHHHHHHHHCCCHHHCCHHHCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
ADKTSRSIRYADLNAGDNAETRRLIDAGNRLADEVARLFPSQPDIADRHYWLEAMINHV
CCCCCCCEEEEECCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
PDYIYAKDTEGRFLIANEVTVADNGLESLQDLVGKTDFDLHPHEFAQAVAGTERRVLETG
CCCEEEECCCCCEEEEECEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHCC
EPIFGIEERAIVTKGRDRWLMTSKVPLRSKSGKIIGIVGISRDITDRKSAERLLEGQARL
CCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
LEMIAKGKPLTEFFNELVLLIEALLPGIKGSILLLSEDGRHLLHGAAPSLDRAYSAAVHA
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHCCCCCHHHHHHHHHHE
LEIGPNAGSCGTAAWRGEQVIVSDVYADPLWADYALLLKSSGLRSCWSTPILSRERKVLG
EEECCCCCCCCCCCCCCCEEEEEHHHCCCHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHH
TFALYAHEVATPCEQEQELIAMAAHLAGIAIERKRAEDRISFLAHHDALTGLPNRVLFEE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
QVDGMLEEIRERDQCAVLAFLDLDNFKLINDSLGHAAGDELLKAVAGRMRASVRKADFVV
HHHHHHHHHHCCCCEEEEEEEECCCCEEECHHCCCCHHHHHHHHHHHHHHHHHHHCCEEE
RVGGDEFIILLNGLPKERDIVLSRLEDIRSAIAMPLQLQGRSLQVSCSMGVACFPNQGRT
EECCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCEEECCCCCCH
AGELLANADMAMYRAKELGRDNIQVFTEEMAARAHERLQWQEELREALAGEEFLLHFQPQ
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
MNLGTGRIFAAEALLRWNHPVRGIISPSVFIPLAEETGLIVPIGDWALRAACRQLKAWQD
CCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHHH
AGLPPLIISVNVSARQFRERNWASRVAEILKETGLEARYLELELTESLIMQDVPGAIATM
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCHHHHHH
HALEAIGVHLAIDDFGTGYSSLSALKRFPVRRLKIDRSFVTDIPLDADDMAITSAIISLA
HHHHHHCEEEEEECCCCCHHHHHHHHHCCHHHEEECHHHHCCCCCCCHHHHHHHHHHHHH
QKLGLRVIAEGVESEAQVEFLQKAGCDEIQGYFFSRPLSAEAFESLLSSARP
HHHHHHHHHHHCCHHHHHHHHHHCCCHHHCCHHHCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]